• Investigative Magnetic Resonance Imaging
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• 제18권3호
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• pp.263-268
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• 2014

신경매독은 스피로헤타(spirochete)인 Treponema pallidum에 의한 뇌와 척수의 드문 감염증이다. 저자들은 53세 남자환자에서 시신경, 삼차신경, 안면신경, 전정와우신경, 중뇌동맥, 후뇌동맥, 척수와 척수막을 침범한 복합적인 수막혈관성, 수막척수염 형태의 신경매독을 경험하여 이를 보고하고자 한다. 본 증례를 통해 뇌수막염과 더불어 뇌신경염, 뇌혈관염이 있고 수막척수염을 동반하는 복합적인 중추신경계 이상 소견이 있어 임상적인 진단이 어려운 경우 신경매독을 감별진단으로 고려하여 영상 소견을 바탕으로 한 빠른 진단이 필요함을 강조하고자 한다.

• Journal of Korean Neurosurgical Society
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• 제46권4호
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• pp.413-416
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• 2009

Since the start of the antibiotic era, syphilis has become rare. However, in recent times, it has tended to be prevalent concomitantly with human immunodeficiency virus (HIV) infection and coinfection in North America and Europe. Now, such cases are expected to increase in elsewhere including Korea. A 40-year-old male patient visited hospital complaining of a headache for about one month. Brain computed tomography and magnetic resonance imaging, showed leptomeninged enhancing mass with edema an right porisylvian region, which was suspected to be glioma. Patient underwent a blood test and was diagnosed with syphilis and acquired immune deficiency syndrome. Partial cortical and subcortical resection were performed after small craniotomy. The dura was thick, adhered to the brain cortex, and was accompanied by hyperemic change of the cortex. The pathologic diagnosis was meningovascular syphilis (MS) in HIV infection. After the operation, the patient was treated with aqueous penicillin G. Thereafter, he had no neurological deficit except intermittent headache. At first, this case was suspected to be glioma, but it was eventually diagnosed as MS in HIV coinfection. At this point the case was judged to be worth reporting.