• Clinical and Experimental Pediatrics
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• 제57권2호
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• pp.75-78
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• 2014

Purpose: This study aimed to investigate the clinical features of macrocephaly at birth in Korea using ultrasonography. Methods: We retrospectively investigated the medical records of full-term birth neonates in Cheil General Hospital & Women's Healthcare Center from January 2000 to June 2012. The following parameters were recorded and analyzed: gestational age, sex, birth weight, height, occipitofrontal circumference (OFC), physical examination, perinatal problems, and ultrasonography results. Macrocephaly was diagnosed when the OFC was greater than two standard deviations, based on the 2007 Korean National Growth Charts. Results: There were 75 neonates with macrocephaly at birth (52 boys and 23 girls), with a mean OFC of $38.1{\pm}0.49cm$. A comparison of the birth weight and height with the OFC value showed that height was correlated with OFC (r=0.35) but birth weight was not correlated with OFC (r=0.06). There were no remarkable findings in 56 cases (75%). Germinal matrix hemorrhage was identified in 10 cases (13%). An enlarged cerebrospinal fluid space was found in 5 cases (6.7%). There were 3 cases of mega-cisterna magna (4%), 1 case of ventriculomegaly, and 1 case of an enlarged interhemispheric space (6 mm) among these patients. In addition, a choroid plexus cyst was seen in 1 case. Mineralizing vasculopathy in both basal ganglia with no evidence of congenital infection was found in 2 cases and an asymptomatic subarachnoid hemorrhage was found in 1 case. Conclusion: Our results indicate that macrocephaly at birth has benign ultrasonography findings and shows a pattern of male dominance.

• Computers and Concrete
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• 제19권1호
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• pp.7-17
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• 2017

In Chinese Design Codes, for super high-rise buildings with complex structural distribution, which are regarded as code-exceeding buildings, elasto-plastic time history analysis is needed to validate the requirement of "no collapse under rare earthquake". In this paper, a 117-story super high-rise building is discussed. It has a height of 597 m and a height-width ratio of 9.5, which have both exceeded the limitations stipulated by the Chinese Design Codes. Mega columns adopted in this structure have cross section area of about $45m^2$ at the bottom, which is infrequent in practical projects. NosaCAD and Perform-3D, both widely used in nonlinear analyses, were chosen in this study, with which two model were established and analyzed, respectively. Elasto-plastic time history analysis was conducted to look into its seismic behavior, emphasizing on the stress state and deformation abilities under intensive seismic excitation.From the comparisons on the results under rare earthquake obtained from NosaCAD and Perform-3D, the overall responses such as roof displacement, inter story drift, base shear and damage pattern of the whole structure from each software show agreement to an extent. Besides, the deformation of the structure is below the limitation of the Chinese Codes, the time sequence and distribution of damages on core tubes are reasonable, and can dissipate certain inputted energy, which indicates that the structure can meet the requirement of "no collapse under rare earthquake".

• 한국산학기술학회논문지
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• 제15권11호
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• pp.6536-6546
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• 2014

본 연구는 스포츠 산업 경쟁력 강화와 생존 전략 마련을 위하여 글로벌 스포츠 시장 트렌드의 미래 변화를 예측하기 위한 것이다. 연구를 위하여 3차에 걸친 델파이 조사에 12개국 21명의 전문가가 참여하여 51개의 미래 예측 의견을 제시하였고, 의견에 대한 참여자들의 수렴을 거쳐 다음과 같은 결론을 얻었다. 첫째, 도핑, 사행 산업 등 윤리적 이슈가 글로벌 시장에 중요한 영향을 미칠 것이다. 둘째, 유소년 스포츠 시장은 지속적으로 성장할 것이다. 셋째, 스포츠는 건강 산업으로서의 중요성이 부각 될 것인데, 특히 저비용 건강 서비스 시장과, 고령인구 대상의 건강 기능 시장이 성장 할 것이다. 넷째, 스포츠 산업의 첨단 기술 /문화 등과의 융 복합은 더욱 가속화 할 것이다. 다섯째, 메가스포츠 이벤트는 다양한 비판적 논란으로 인하여 미래가 불투명해질 것이다. 여섯째, 소셜 미디어 등 신 미디어와 구 미디어의 스포츠에 대한 영향력은 더욱 증대될 것이다. 마지막으로 문화현상으로서의 스포츠시장 글로벌화는 더욱 가속화 될 것이다.

• Asian Pacific Journal of Cancer Prevention
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• 제14권12호
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• pp.7221-7227
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• 2013

Background: Fascin, an actin-bundling protein forming actin bundles including filopodia and stress fibers, is overexpressed in multiple human epithelial cancers including esophageal squamous cell carcinoma (ESCC). Previously we conducted a microarray experiment to analyze fascin knockdown by RNAi in ESCC. Method: In this study, the differentially expressed genes from mRNA expression profilomg of fascin knockdown were analyzed by multiple bioinformatics methods for a comprehensive understanding of the role of fascin. Results: Gene Ontology enrichment found terms associated with cytoskeleton organization, including cell adhesion, actin filament binding and actin cytoskeleton, which might be related to fascin function. Except GO categories, the differentially expressed genes were annotated by 45 functional categories from the Functional Annotation Chart of DAVID. Subpathway analysis showed thirty-nine pathways were disturbed by the differentially expressed genes, providing more detailed information than traditional pathway enrichment analysis. Two subpathways derivated from regulation of the actin cytoskeleton were shown. Promoter analysis results indicated distinguishing sequence patterns and transcription factors in response to the co-expression of downregulated or upregulated differentially expressed genes. MNB1A, c-ETS, GATA2 and Prrx2 potentially regulate the transcription of the downregulated gene set, while Arnt-Ahr, ZNF42, Ubx and TCF11-MafG might co-regulate the upregulated genes. Conclusions: This multiple bioinformatic analysis helps provide a comprehensive understanding of the roles of fascin after its knockdown in ESCC.

• 한국항해항만학회지
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• 제30권3호
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• pp.211-217
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• 2006

최근 세계의 항만은 중국 효과 및 세계 물동량의 지속적인 증가에 따라 항만 체증은 갈수록 심화되고 있다. 선사는 선박의 대형화를 통한 물류비 절감을 위하여 기항지 항만의 축소에 따라 지역 내 항만간의 경쟁은 치열해지고 있다. 항만 체증에 따라 선사는 선박대기시간비율과 재항시간 등의 항만 서비스품질 (QoS : Quality of Service)을 기항지로 선택하는 평가기준으로 활용한다. 본 논문에서는 최근 신성장 산업의 기반 기술로 급부상하고 있는 RFID (Radio Frequence IDentification) 기술을 항만 운영시스템에 활용함으로써 트윈리프트 갠트리크레인 (Twin-lift Gantry Crane)의 하역 생산성의 개선 방안을 제안한다. 본 논문의 목적은 RFID기반의 RTLS(Real Time Location System)을 활용하여 항만 QoS가 보장되는 유비쿼터스 항만(U-Port)의 새로운 비즈니스 모델을 제안하는데 있다.

• 상하수도학회지
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• 제34권5호
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• pp.335-344
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• 2020

Due to global climate change, mega-droughts have occurred frequently. Since long-term droughts make it difficult to secure the water resources, water supply needs to be restricted in a reasonable manner. In the event of limited water supply, the waterworks need to develop a restricted water supply strategy. This study showed that analyzing daily water supply could be used to respond to the first stage of a drought. According to an analysis of Korea's major water authorities, there was about 7~21% of room for daily minimum water supply in case of a drought. Restricting the water supply by lowering pressure is a good strategy for local water authorities with high water leakage rate since leakage is inversely dependent with pressure. For this method, it is necessary to quantify water deficiency and pressure at each node using a simulation. Since DDA-based software is not possible to predict changes in demand at nodes with pressure reduction, WaterGEMS, a PDA software, was used to quantitatively predict water shortages and pressures at each node. Locations where water is deficient need to install booster pumps or to be dispatched with water tank truck and bottled water. Without these support, lowering pressure could not be an option for water works. This paper suggests a method for waterworks to plan a drought by lowering pressure to restrict water supply using daily water supply analysis and PDA based simulation.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제41권
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• pp.41.1-41.6
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• 2019

Backgrounds: The purpose of this study is to discuss the total joint reconstruction surgery for a patient with recurrent ankylosis in bilateral temporomandibular joints (TMJs) using three-dimensional (3D) virtual surgical planning, computer-aided manufacturing (CAD/CAM)-fabricated surgical guides, and stock TMJ prostheses. Case presentation: A 66-year-old female patient, who had a history of multiple TMJ surgeries, complained of severe difficulty in eating and trismus. The 3D virtual surgery was performed with a virtual surgery software (FACEGIDE, MegaGen implant, Daegu, South Korea). After confirmation of the location of the upper margin for resection of the root of the zygoma and the lower margin for resection of the ankylosed condyle, and the position of the fossa and condyle components of stock TMJ prosthesis (Biomet, Jacksonville, FL, USA), the surgical guides were fabricated with CAD/CAM technology. Under general anesthesia, osteotomy and placement of the stock TMJ prosthesis (Biomet) were carried out according to the surgical planning. At 2 months after the operation, the patient was able to open her mouth up to 30 mm without complication. Conclusion: For a patient who has recurrent ankylosis in bilateral TMJs, total joint reconstruction surgery using 3D virtual surgical planning, CAD/CAM-fabricated surgical guides, and stock TMJ prostheses may be an effective surgical treatment option.

• Journal of Radiation Protection and Research
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• 제41권2호
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• pp.81-86
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• 2016

Background: For positron emission tomography (PET) application, cadmium zinc telluride (CZT) has been investigated by several institutes to replace detectors from a conventional system using photomultipliers or Silicon-photomultipliers (SiPMs). The spatial and energy resolution in using CZT can be superior to current scintillator-based state-of-the-art PET detectors. CZT has been under development for several years at the Korea Atomic Energy Research Institute (KAERI) to provide a high performance gamma ray detection, which needs a single crystallinity, a good uniformity, a high stopping power, and a wide band gap. Materials and Methods: Before applying our own grown CZT detectors in the prototype PET system, we investigated preliminary research with a developed discrete type data acquisition (DAQ) system for coincident events at 128 anode pixels and two common cathodes of two CZT detectors from Redlen. Each detector has a $19.4{\times}19.4{\times}6mm^3$ volume size with a 2.2 mm anode pixel pitch. Discrete amplifiers consist of a preamplifier with a gain of $8mV{\cdot}fC^{-1}$ and noise of 55 equivalent noise charge (ENC), a $CR-RC^4$ shaping amplifier with a $5{\mu}s$ peak time, and an analog-to-digital converter (ADC) driver. The DAQ system has 65 mega-sample per second flash ADC, a self and external trigger, and a USB 3.0 interface. Results and Discussion: Characteristics such as the current-to-voltage curve, energy resolution, and electron mobility life-time products for CZT detectors are investigated. In addition, preliminary results of gamma ray imaging using 511 keV of a $^{22}Na$ gamma ray source were obtained. Conclusion: In this study, the DAQ system with a CZT radiation sensor was successfully developed and a PET image was acquired by two sets of the developed DAQ system.

• 콘크리트학회논문집
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• 제28권2호
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• pp.129-139
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• 2016

대형 PC기둥의 양중부하를 줄이고 접합부의 구조일체성을 개선하기 위한 대안으로서, 중공 PC기둥이 사용될 수 있다. 본 연구에서는 PC부의 생산성과 구조일체성을 개선한 새로운 중공 PC기둥을 개발하였다. PC부를 제작하기 위하여 구조용 골형플레이트를 내부영구거푸집과 수평 관통철근을 사용하였다. 제안된 PC기둥의 내진성능을 검증하기 위하여, 1/2 스케일의 기둥 실험체 4개에 대하여 일정 축력에서 반복 횡가력실험을 수행하였다. 실험 변수로는 횡철근 간격, 강섬유 사용여부, 그리고 PC부의 두께가 고려되었다. 실험 결과, 제안된 PC기둥은 외곽 PC부의 취성적인 파괴 없이 우수한 하중재하능력과 변형능력을 보이는 것으로 나타났다. PC부에 횡철근을 촘촘히 배근하거나 강섬유를 사용할 경우, PC 콘크리트의 탈락을 제한하여 변형능력을 증가시킬 수 있었다.

• 한국지반환경공학회 논문집
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• 제10권3호
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• pp.29-36
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• 2009

본 논문에서는 초고층 건축물이 풍화대지반에 위치하여 대구경 현장타설 말뚝기초로 지지되고 있는 사례를 분석하였다. 본 논문에서 제시한 말뚝기초의 설계 사례는 "예비설계-검증시험-예비설계의 보완"의 3단계를 거쳐 말뚝기초의 설계를 완성한 대표적인 사례로 볼 수 있으며, 검증시험으로 2회의 양방향 고유압 말뚝재하시험이 수행되었다. 이와 같은 설계절차를 준수할 경우 말뚝기초의 경제적인 설계를 수행할 수 있으며, 이를 통하여 말뚝기초 공사비의 대폭적인 절감을 이룰 수 있을 것이다.