• Title/Summary/Keyword: MegaStudy

Search Result 471, Processing Time 0.024 seconds

Clinical features of macrocephaly at birth in Korea

  • Jeong, Goun;Kim, Minkyun;Han, Byoung Hee
    • Clinical and Experimental Pediatrics
    • /
    • v.57 no.2
    • /
    • pp.75-78
    • /
    • 2014
  • Purpose: This study aimed to investigate the clinical features of macrocephaly at birth in Korea using ultrasonography. Methods: We retrospectively investigated the medical records of full-term birth neonates in Cheil General Hospital & Women's Healthcare Center from January 2000 to June 2012. The following parameters were recorded and analyzed: gestational age, sex, birth weight, height, occipitofrontal circumference (OFC), physical examination, perinatal problems, and ultrasonography results. Macrocephaly was diagnosed when the OFC was greater than two standard deviations, based on the 2007 Korean National Growth Charts. Results: There were 75 neonates with macrocephaly at birth (52 boys and 23 girls), with a mean OFC of $38.1{\pm}0.49cm$. A comparison of the birth weight and height with the OFC value showed that height was correlated with OFC (r=0.35) but birth weight was not correlated with OFC (r=0.06). There were no remarkable findings in 56 cases (75%). Germinal matrix hemorrhage was identified in 10 cases (13%). An enlarged cerebrospinal fluid space was found in 5 cases (6.7%). There were 3 cases of mega-cisterna magna (4%), 1 case of ventriculomegaly, and 1 case of an enlarged interhemispheric space (6 mm) among these patients. In addition, a choroid plexus cyst was seen in 1 case. Mineralizing vasculopathy in both basal ganglia with no evidence of congenital infection was found in 2 cases and an asymptomatic subarachnoid hemorrhage was found in 1 case. Conclusion: Our results indicate that macrocephaly at birth has benign ultrasonography findings and shows a pattern of male dominance.

Elasto-plastic time history analysis of a 117-story high structure

  • Wu, Xiaohan;Li, Yimiao;Zhang, Yunlei
    • Computers and Concrete
    • /
    • v.19 no.1
    • /
    • pp.7-17
    • /
    • 2017
  • In Chinese Design Codes, for super high-rise buildings with complex structural distribution, which are regarded as code-exceeding buildings, elasto-plastic time history analysis is needed to validate the requirement of "no collapse under rare earthquake". In this paper, a 117-story super high-rise building is discussed. It has a height of 597 m and a height-width ratio of 9.5, which have both exceeded the limitations stipulated by the Chinese Design Codes. Mega columns adopted in this structure have cross section area of about $45m^2$ at the bottom, which is infrequent in practical projects. NosaCAD and Perform-3D, both widely used in nonlinear analyses, were chosen in this study, with which two model were established and analyzed, respectively. Elasto-plastic time history analysis was conducted to look into its seismic behavior, emphasizing on the stress state and deformation abilities under intensive seismic excitation.From the comparisons on the results under rare earthquake obtained from NosaCAD and Perform-3D, the overall responses such as roof displacement, inter story drift, base shear and damage pattern of the whole structure from each software show agreement to an extent. Besides, the deformation of the structure is below the limitation of the Chinese Codes, the time sequence and distribution of damages on core tubes are reasonable, and can dissipate certain inputted energy, which indicates that the structure can meet the requirement of "no collapse under rare earthquake".

Market Trends Prediction of the Sports Industry (글로벌 스포츠 산업 트렌드 예측)

  • Kim, Hun-Il
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.15 no.11
    • /
    • pp.6536-6546
    • /
    • 2014
  • The aim of this study was to predict the global sports market trend to make developmental and strategic marketing planning for governments, enterprises and scholars. By participating in Delphi, 21 professionals from 12 countries came up with 51 foresights. In addition, the following 7 final results emerged after 3 rounds of discussion. First, integrity issues (e.g., doping and gambling) will increase in the sports industry. Second, the market of youth sports will continue to grow worldwide. Third, the health-oriented sports service will growth, particularly for seniors or people with less wealth. Fourth, the convergence with high-technology, culture and leisure activity will be accelerated. Fifth, mega sports events will receive increasing scrutiny and criticism. Sixth, the leverage of new media (e.g., social media) as well as old media (e.g., TV and magazines) will expand in the sports industry. Finally, globalization, which is similar to the culture phenomenon, will be accelerated in the sports industry.

Comprehensive Bioinformation Analysis of the MRNA Profile of Fascin Knockdown in Esophageal Squamous Cell Carcinoma

  • Wu, Bing-Li;Luo, Lie-Wei;Li, Chun-Quan;Xie, Jian-Jun;Du, Ze-Peng;Wu, Jian-Yi;Zhang, Pi-Xian;Xu, Li-Yan;Li, En-Min
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.14 no.12
    • /
    • pp.7221-7227
    • /
    • 2013
  • Background: Fascin, an actin-bundling protein forming actin bundles including filopodia and stress fibers, is overexpressed in multiple human epithelial cancers including esophageal squamous cell carcinoma (ESCC). Previously we conducted a microarray experiment to analyze fascin knockdown by RNAi in ESCC. Method: In this study, the differentially expressed genes from mRNA expression profilomg of fascin knockdown were analyzed by multiple bioinformatics methods for a comprehensive understanding of the role of fascin. Results: Gene Ontology enrichment found terms associated with cytoskeleton organization, including cell adhesion, actin filament binding and actin cytoskeleton, which might be related to fascin function. Except GO categories, the differentially expressed genes were annotated by 45 functional categories from the Functional Annotation Chart of DAVID. Subpathway analysis showed thirty-nine pathways were disturbed by the differentially expressed genes, providing more detailed information than traditional pathway enrichment analysis. Two subpathways derivated from regulation of the actin cytoskeleton were shown. Promoter analysis results indicated distinguishing sequence patterns and transcription factors in response to the co-expression of downregulated or upregulated differentially expressed genes. MNB1A, c-ETS, GATA2 and Prrx2 potentially regulate the transcription of the downregulated gene set, while Arnt-Ahr, ZNF42, Ubx and TCF11-MafG might co-regulate the upregulated genes. Conclusions: This multiple bioinformatic analysis helps provide a comprehensive understanding of the roles of fascin after its knockdown in ESCC.

A Study on RFID Based Biz-Model for QoS Guarantee for Container Terminals (RFID를 활용한 컨테이너터미널의 QoS 보장을 위한 비즈니스 모델 연구)

  • Park Doo-Jin;Park Jin-Hee;Kim Hyun;Nam Ki-Chan
    • Journal of Navigation and Port Research
    • /
    • v.30 no.3 s.109
    • /
    • pp.211-217
    • /
    • 2006
  • In recent years, the pileup of world ports is deepening as time goes by due to China effect and continuous increase of world trade volume. The shipping companies try to reduce their shipping cost by using mega vessels in the ports. Shipping companies consider most of the ships turnaround time as a critical factor when selecting a calling port for reducing cost. This paper will suggest how we can guarantee terminal QoS like ship waiting time ratio and ship residing time applying RFID(Radio Frequence IDentification) technology, raising up rapidly as a fundamental solution of new growing industry to port information system. Also, lead time of whole port logistics can be decreased for reduction of loading & discharging time and result from productivity improvement of Twin-lift G/C(Gantry Crane} as applying RFID technology to terminal operation. The purpose of this paper suggests that the new business model of U-Port which port QoS can be guaranteed using RFID based RTLS technology.

Pressure restricted water supply method during drought using a computer simulation and daily water supply analysis (시뮬레이션과 1일 급수량 분석을 이용한 갈수기 감압에 의한 제한급수 방법)

  • Nam, Youngwook;Kim, Kyungsu;Hyun, Inhwan;Kim, Dooil
    • Journal of Korean Society of Water and Wastewater
    • /
    • v.34 no.5
    • /
    • pp.335-344
    • /
    • 2020
  • Due to global climate change, mega-droughts have occurred frequently. Since long-term droughts make it difficult to secure the water resources, water supply needs to be restricted in a reasonable manner. In the event of limited water supply, the waterworks need to develop a restricted water supply strategy. This study showed that analyzing daily water supply could be used to respond to the first stage of a drought. According to an analysis of Korea's major water authorities, there was about 7~21% of room for daily minimum water supply in case of a drought. Restricting the water supply by lowering pressure is a good strategy for local water authorities with high water leakage rate since leakage is inversely dependent with pressure. For this method, it is necessary to quantify water deficiency and pressure at each node using a simulation. Since DDA-based software is not possible to predict changes in demand at nodes with pressure reduction, WaterGEMS, a PDA software, was used to quantitatively predict water shortages and pressures at each node. Locations where water is deficient need to install booster pumps or to be dispatched with water tank truck and bottled water. Without these support, lowering pressure could not be an option for water works. This paper suggests a method for waterworks to plan a drought by lowering pressure to restrict water supply using daily water supply analysis and PDA based simulation.

Total joint reconstruction using computer-assisted surgery with stock prostheses for a patient with bilateral TMJ ankylosis

  • Rhee, Seung-Hyun;Baek, Seung-Hak;Park, Sang-Hun;Kim, Jong-Cheol;Jeong, Chun-Gi;Choi, Jin-Young
    • Maxillofacial Plastic and Reconstructive Surgery
    • /
    • v.41
    • /
    • pp.41.1-41.6
    • /
    • 2019
  • Backgrounds: The purpose of this study is to discuss the total joint reconstruction surgery for a patient with recurrent ankylosis in bilateral temporomandibular joints (TMJs) using three-dimensional (3D) virtual surgical planning, computer-aided manufacturing (CAD/CAM)-fabricated surgical guides, and stock TMJ prostheses. Case presentation: A 66-year-old female patient, who had a history of multiple TMJ surgeries, complained of severe difficulty in eating and trismus. The 3D virtual surgery was performed with a virtual surgery software (FACEGIDE, MegaGen implant, Daegu, South Korea). After confirmation of the location of the upper margin for resection of the root of the zygoma and the lower margin for resection of the ankylosed condyle, and the position of the fossa and condyle components of stock TMJ prosthesis (Biomet, Jacksonville, FL, USA), the surgical guides were fabricated with CAD/CAM technology. Under general anesthesia, osteotomy and placement of the stock TMJ prosthesis (Biomet) were carried out according to the surgical planning. At 2 months after the operation, the patient was able to open her mouth up to 30 mm without complication. Conclusion: For a patient who has recurrent ankylosis in bilateral TMJs, total joint reconstruction surgery using 3D virtual surgical planning, CAD/CAM-fabricated surgical guides, and stock TMJ prostheses may be an effective surgical treatment option.

Preliminary Research of CZT Based PET System Development in KAERI

  • Jo, Woo Jin;Jeong, Manhee;Kim, Han Soo;Kim, Sang Yeol;Ha, Jang Ho
    • Journal of Radiation Protection and Research
    • /
    • v.41 no.2
    • /
    • pp.81-86
    • /
    • 2016
  • Background: For positron emission tomography (PET) application, cadmium zinc telluride (CZT) has been investigated by several institutes to replace detectors from a conventional system using photomultipliers or Silicon-photomultipliers (SiPMs). The spatial and energy resolution in using CZT can be superior to current scintillator-based state-of-the-art PET detectors. CZT has been under development for several years at the Korea Atomic Energy Research Institute (KAERI) to provide a high performance gamma ray detection, which needs a single crystallinity, a good uniformity, a high stopping power, and a wide band gap. Materials and Methods: Before applying our own grown CZT detectors in the prototype PET system, we investigated preliminary research with a developed discrete type data acquisition (DAQ) system for coincident events at 128 anode pixels and two common cathodes of two CZT detectors from Redlen. Each detector has a $19.4{\times}19.4{\times}6mm^3$ volume size with a 2.2 mm anode pixel pitch. Discrete amplifiers consist of a preamplifier with a gain of $8mV{\cdot}fC^{-1}$ and noise of 55 equivalent noise charge (ENC), a $CR-RC^4$ shaping amplifier with a $5{\mu}s$ peak time, and an analog-to-digital converter (ADC) driver. The DAQ system has 65 mega-sample per second flash ADC, a self and external trigger, and a USB 3.0 interface. Results and Discussion: Characteristics such as the current-to-voltage curve, energy resolution, and electron mobility life-time products for CZT detectors are investigated. In addition, preliminary results of gamma ray imaging using 511 keV of a $^{22}Na$ gamma ray source were obtained. Conclusion: In this study, the DAQ system with a CZT radiation sensor was successfully developed and a PET image was acquired by two sets of the developed DAQ system.

Cyclic Lateral Loading Test for Cast-In-Place Concrete-Filled Hollow PC Columns Using Permanent Inner form (영구 내부거푸집을 이용한 현장타설 콘크리트 채움중공 PC기둥의 반복횡가력실험)

  • Lee, Ho-Jun;Park, Hong-Gun;Kim, Chang-Soo;Hwang, Hyeon-Jong
    • Journal of the Korea Concrete Institute
    • /
    • v.28 no.2
    • /
    • pp.129-139
    • /
    • 2016
  • Cast-in-place concrete-filled hollow PC (HPC) columns are used to reduce lifting load of heavy-weight PC columns and to improve the structural integrity of joints. In the present study, a new type of HPC column was proposed to improve the productivity and structural integrity of the concrete. To form the hollow PC columns, a permanent inner form was prefabricated using structural deck plates and penetrated lateral bars. Half-scale specimens of four HPC columns were tested under combined axial compression and lateral cyclic loading to evaluate the seismic resistance. In the design of test specimens, various parameters such as the spacing of lateral re-bars, the use of steel fiber, and the thickness of PC cover were considered. The test results showed that the proposed HPC columns generally exhibited satisfactory load-carrying capacity and deformation capacity without brittle failure of PC. If closely spaced hoops or fiber reinforcements are used for PC, the deformation capacity can be improved further by restraining PC spalling.

A Study on the Design Procedure of Mega Foundations for a High-rise Building Using Bi-Directional High Pressure Pile Load Test (BDH PLT) (양방향 고유압 말뚝재하시험(BDH PLT)을 이용한 초고층 건축물의 대구경 현장타설말뚝 설계절차에 관한 연구)

  • Kim, Sung-Ho;Choi, Yongkyu
    • Journal of the Korean GEO-environmental Society
    • /
    • v.10 no.3
    • /
    • pp.29-36
    • /
    • 2009
  • In this paper, a case of a high-rise building supported by a large-diameter drilled shaft socketed in a weathered ground has been studied. The design case of pile foundation presented in this paper could be a representative example of execution of pile design through three(3) design stages of "preliminary design-proof test-supplementary design". As proof test, two(2) BDH PLT (Bi-directional High Pressure Pile Load Test) were performed at the early construction stage. By following the design process of this way, the economic pile design could be carried out and a large amount of construction cost saving could be realized.

  • PDF