• Title/Summary/Keyword: Medicine classification

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Comparison of arch forms between Korean and Japanese in Class I, II, and III malocclusion (한국인과 일본인 부정교합자의 하악 치열궁 헝태 비교)

  • Lee, Chae-Hyung;Mo, Sung-Seo;Kang, Yoon-Goo;Nojima, Kunihiko;Kim, Young-Ho;Kook, Yoon-Ah
    • The korean journal of orthodontics
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    • v.37 no.5
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    • pp.364-375
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    • 2007
  • The purpose of this study was to compare arch dimensions and frequency distribution of arch forms between Korean and Japanese Class I, II, and III malocclusion groups. Methods: The sample consisted of 368 Korean cases (114 Class I, 119 Class II, and 135 Class III malocclusion) and 160 Japanese cases (60 Class I, 50 Class II, and 50 Class III malocclusion). The most facial portion of 13 proximal contact areas was digitized from photocopied images of the mandibular dental arches. Clinical bracket slot points were calculated for each tooth based on mandibular tooth thickness data. Four linear and two proportional measurements were taken. Measurements are statistically analyzed in each malocclusion group. The dental arches were classified into square, ovoid, and tapered forms to determine and compare the frequency distributions between the two ethnic groups. Results: The findings of this study showed that Japanese females in Class I and II groups had a statistically significant narrower mandibular dental arch width compared with the Japanese males, Korean males and Korean females. But in the Class III group, there was no significant difference in the mandibular dental arch size according to the two ethnic groups and genders. Conclusions: The majority of Koreans and Japanese in all the malocclusion groups exhibited square and ovoid arch forms. The most frequent arch forms found in Koreans was square but ovoid for Japanese.

Operative Treatment with Anatomically Preshaped Locking Compression Plate in Distal Fibular Fracture (해부학적 잠김 압박 금속판을 이용한 원위 비골 골절의 치료)

  • Chung, Hyung-Jin
    • Journal of Korean Foot and Ankle Society
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    • v.17 no.2
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    • pp.130-135
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    • 2013
  • Purpose: Preshaped Locking compression plate(LCP) has holes with fixed angle between screw and plate and have advantage firm fixation because it has stability of angular and axial deformity. We evaluated usefulness of LCP after open reduction and internal fixation in distal fibular fracture. Materials and Methods: Between December 2011 and May 2012, 23 patients with fracture of distal fibula were followed up at least 12 months underwent open reduction and internal fixation with LCP. There were 15 males and 8 females with a mean age 39.8(20~69) years. According to Danis-Weber classification, there were 20 cases of type B and 3 cases of type C. There were 13 cases of isolated lateral malleolus fractures, 1 case of bimalleolar fracture, 6 cases of trimalleolar fractures and 3 cases of distal tibia fractures with proximal fibula fracture. Intraoperatively, we assessed whether preshaped LCP fit lateral margin of distal fibula or not and evaluated quality of reduction and postoperative complications. The cases were analyzed by radiological bone union time and clinical results according to the criteria of Meyer Results: Of all cases, complete bone union was achieved and average radiological bone union time was 7.3(6~12) weeks. The clinical results were excellent in 18 cases(78%), good in 5 cases(22%). There were 5 cases of plate with 3 holes, 13 cases of plate with 4 holes, 2 cases of plate with 5 holes, 1 case of plate with 6 holes and 2 cases of plate with 7 holes. The average number of screws at proximal fragement was 2.5 and at distal fragment was 3.5. In 14 cases (60.8 %), we needed re-bending of plate because the distance between plate and lateral cortical margin of distal fibula was more than 5 mm at anteroposterior X-ray after reduction. All cases have anatomical reduction and there were no complications of wound infections. There were no complaint about hardware irritation. Conclusion: At fractures of distal fibula,preshaped LCP had a excellent stability although far cortex was not fixed with screw and bending of plate. And there are less complications of hardware irritation and wound problems. But, Some complement would be needed because there were no complete fitting between precontour of LCP and lateral cortical margin of distal fibula.

Knowledge and Attitudes of Oncology Nurses Toward Cancer Pain Managements (암 병동 간호사의 통증관리에 대한 지식과 태도)

  • Gong, Soung-Wha;Bang, Jji-Yha;Seo, Min-Sook;Hyun, Sin-Sook;Kim, Hee-Jung;Lee, Mi-Ae;Lee, Mi-Ae;You, Hyen-Hee;Her, Jae-Kyoung;Kim, Eun-Ae;Park, Kyung-Sook
    • Korean Journal of Adult Nursing
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    • v.16 no.1
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    • pp.5-16
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    • 2004
  • Purpose: The purpose of this study is to evaluate the knowledge and attitudes of oncology ward nurses toward cancer pain management and to find ways to improve the educational program for nurses. Method: A total of 209 nurses working at the oncology ward of three hospitals in Seoul and a Gyenggi Province. The survey instrument used was the 32-item scale for evaluating nurses knowledge and attitudes originally developed by McCaffery and Ferrell'(1990), that was by Kim'(1997). Result: In terms of the nurses knowledge of pain management, the result showed that the nurses scored an average of 67.8 out of 100 for phamacokinetics of opioids, 84.8 for classification of analgesics, 60.1 for pain assessment, and 70.7 for drug administration. 18.2% of the nurses hesitate to inject the narcotic agent because of concerns regarding the drug's potential side effects. there was significant difference in the knowledge of pain management according to the general characteristics of pain in terms of the nurses age(p=.001), position (p=.016), years of experiences(p=.002), experience of cancer pain education(p=.001). Conclusion: The also showed that nurses working at cancer ward lack knowledge. It is important to provide intensive education to nurses about cancer pain management.

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Association Between the GSTP1 Codon 105 Polymorphism and Gastric Cancer Risk: an Updated Meta-analysis

  • Bao, Li-Dao;Niu, Jian-Xiang;Song, Hui;Wang, Yi;Ma, Rui-Lian;Ren, Xian-Hua;Wu, Xin-Lin
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.8
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    • pp.3687-3693
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    • 2012
  • Objective: The current meta-analysis was performed to address a more accurate estimation of the association between glutathione S-transferase P1 (GSTP1) codon 105 polymorphism and risk of gastric cancer (GC), which has been widely reported with conflicting results. Methods: A comprehensive literature search was conducted to identify all the relevant studies. Fixed or random effect models were selected based on the heterogeneity test. Publication bias was estimated using Begg's funnel plots and Egger's regression test. Results: A total of 20 studies containing 2,821 GC cases and 6,240 controls were finally included in the analyses. Overall, no significant association between GSTP1 polymorphism and GC risk was observed in worldwide populations. However, subgroup analysis stratified by ethnicity showed that GSTP1 polymorphism was significantly associated with increased risk of GC in Asians (G vs. A, OR = 1.273, 95%CI=1.011-1.605; GG vs. AA, OR=2.103, 95%CI=1.197-3.387; GG vs. AA+AG, OR =2.103, 95%CI=1.186-3.414). In contrast, no significant association was found in Caucasians in any genetic models, except for with AG vs. AA (OR=0.791, 95%CI=0.669-0.936). Furthermore, the GSTP1 polymorphism was found to be significantly associated with GC in patients with H. pylori infection and in those with a cardiac GC. Subgroup analysis stratified by Lauren's classification and smoking status showed no significant association with any genetic model. No studies were found to significantly influence the pooled effects in each genetic mode, and no potential publication bias was detected. Conclusion: This meta-analysis suggested that the GSTP1 polymorphism might be associated with increased risk of GC in Asians, while GSTP1 heterozygote genotype seemed to be associated with reduced risk of GC. Since potential confounders could not be ruled out completely, further studies are needed to confirm these results.

Gramene database: A resource for comparative plant genomics, pathways and phylogenomics analyses

  • Tello-Ruiz, Marcela K.;Stein, Joshua;Wei, Sharon;Preece, Justin;Naithani, Sushma;Olson, Andrew;Jiao, Yinping;Gupta, Parul;Kumari, Sunita;Chougule, Kapeel;Elser, Justin;Wang, Bo;Thomason, James;Zhang, Lifang;D'Eustachio, Peter;Petryszak, Robert;Kersey, Paul;Lee, PanYoung Koung;Jaiswal, kaj;Ware, Doreen
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2017.06a
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    • pp.135-135
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    • 2017
  • The Gramene database (http://www.gramene.org) is a powerful online resource for agricultural researchers, plant breeders and educators that provides easy access to reference data, visualizations and analytical tools for conducting cross-species comparisons. Learn the benefits of using Gramene to enrich your lectures, accelerate your research goals, and respond to your organismal community needs. Gramene's genomes portal hosts browsers for 44 complete reference genomes, including crops and model organisms, each displaying functional annotations, gene-trees with orthologous and paralogous gene classification, and whole-genome alignments. SNP and structural diversity data, available for 11 species, are displayed in the context of gene annotation, protein domains and functional consequences on transcript structure (e.g., missense variant). Browsers from multiple species can be viewed simultaneously with links to community-driven organismal databases. Thus, while hosting the underlying data for comparative studies, the portal also provides unified access to diverse plant community resources, and the ability for communities to upload and display private data sets in multiple standard formats. Our BioMart data mining interface enable complex queries and bulk download of sequence, annotation, homology and variation data. Gramene's pathway portal, the Plant Reactome, hosts over 240 pathways curated in rice and inferred in 66 additional plant species by orthology projection. Users may compare pathways across species, query and visualize curated expression data from EMBL-EBI's Expression Atlas in the context of pathways, analyze genome-scale expression data, and conduct pathway enrichment analysis. Our integrated search database and modern user interface leverage these diverse annotations to facilitate finding genes through selecting auto-suggested filters with interactive views of the results.

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Metastatic Axillary Lymph Node Ratio (LNR) is Prognostically Superior to pN Staging in Patients with Breast Cancer -- Results for 804 Chinese Patients from a Single Institution

  • Xiao, Xiang-Sheng;Tang, Hai-Lin;Xie, Xin-Hua;Li, Lai-Sheng;Kong, Ya-Nan;Wu, Min-Qing;Yang, Lu;Gao, Jie;Wei, Wei-Dong;Xie, Xiaoming
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.9
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    • pp.5219-5223
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    • 2013
  • The number of axillary lymph nodes involved and retrieved are important prognostic factors in breast cancer. The purpose of our study was to investigate whether the lymph node ratio (LNR) is a better prognostic factor in predicting disease-free survival (DFS) for breast cancer patients as compared with pN staging. The analysis was based on 804 breast cancer patients who had underwent axillary lymph node dissection between 1999 and 2008 in Sun Yat-Sen University Cancer Center. Optimal cutoff points of LNR were calculated using X-tile software and validated by bootstrapping. Patients were then divided into three groups (low-, intermediate-, and high-risk) according to the cutoff points. Predicting risk factors for relapse were performed according to Cox proportional hazards analysis. DFS was estimated using the Kaplan-Meier method and compared by the log-rank test. The 5-year DFS rate decreased significantly with increasing LNRs and pN. Univariate analysis found that the pT, pN, LNR, molecule type, HER2, pTNM stage and radiotherapy well classified patients with significantly different prognosis. By multivariate analysis, only LNR classification was retained as an independent prognostic factor. Furthermore, there was a significant prognostic difference among different LNR categories for pN2 category, but no apparent prognostic difference was seen between different pN categories in any LNR category. Therefore, LNR rather than pN staging is preferable in predicting DFS in node positive breast cancer patients, and routine clinical decision-making should take the LNR into consideration.

A Study of Parallel Test Among Three ADVIA 2120 System (3대의 ADVIA 2120 System 평행시험에 대한 연구)

  • Chang, Sang-Wu;Cho, Eun-Hae;Kim, Nam-Yong;Chu, Kyung-Bok;Lee, Suk-Jong;Hong, Sung-No;Oh, Jong-Do
    • Korean Journal of Clinical Laboratory Science
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    • v.38 no.1
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    • pp.16-21
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    • 2006
  • Parallel testing means ordering a number of tests at the same time so abnormalities in any of the tests can be found quickly and used in making the diagnosis. This is a good medical strategy to eliminate diseases and it is relatively inexpensive if all the tests are potential sources of information and performed on the same analyzer. In regression, the equation for the straight line is recast as y = bx + a. This change in terminology leads to confusion. Here a is the y-intercept or constant and b is the coefficient or slope of the line. A few more words of caution about regression - as in all of statistics there are certain assumptions: the x value is a true measure, both X and Y distributions are normal, and homoscedasticity, i.e., the variance of y is the same for each value of x. In this study the linearity classification made by different scientists were always in agreement. Typical examples of curves that were considered linear are presented in Fig. 1-5. Because these automated procedures values were usually within five percent of each other the curvature could be easily detected. The plot of the WBC, RBC, hemoglobin, hematocrit and platelet concentrations from approximately 74.4 to $0{\times}10^3/{\mu}L$ and $80.4-0{\times}10^3/{\mu}L$, $5.6-0{\times}10^6/{\mu}L$ and $6.1-0{\times}1106/{\mu}L$, 18.3-0 g/dL and 19.0-0 g/dL, 54.1-0% and 56.8-0% and 642.0 to $0.03{\times}10^3{\mu}L$ and $754.0-0{\times}10^3/{\mu}L$ on the ADVIA 2120 C Versus and A and B typical of an acceptable linear study as shown in Fig. 1-5. The grand mean of R2, intercept and slope is 0.99898, 0.99459 and 1.54626.

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Implementation of Falls Detection System Using 3-axial Accelerometer Sensor (3축 가속도 센서를 이용한 낙상 검출 시스템 구현)

  • Jeon, Ah-Young;Yoo, Ju-Yeon;Park, Geun-Chul;Jeon, Gye-Rok
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.11 no.5
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    • pp.1564-1572
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    • 2010
  • In this study, the falls detection and direction classification system was implemented using 3-axial acceleration signal. The acceleration signals were acquired from the 3-axial accelerometer(MMA7260Q, Freescale, USA), and then transmitted to the computer through USB interface. The implemented system can detect falls using the newly proposed algorithm, and also classify the direction of falls using fuzzy classifier. The 6 subjects was selected for experiment and the accelerometer was attached on each subject's chest. Each subject walked in normal pace for 5 seconds, and then the fall down according to the four direction(front_fall, back_fall, left_fall and right_fall) during at least 2 second. The falls was easily detect using the newly proposed algorithm in this study. The acquired signals were analyzed after 1 second from generating falls. The fuzzy classifier was used to classify the direction of falls. The mean value of the falls detection rate was 94.79%. The classifier rate according to falls direction were 95.83% in case of front falls, 100% incase of back falls, 87.5% in case of left falls, and 95.83% in case of right falls.

The study on toothbrush filaments (칫솔 강모 형태에 관한 연구)

  • Han, Seung-Min;Yang, Seung-Min;Lee, Young-Moo;Ku, Young;Rhyu, In-Chul;Chung, Chong-Pyoung;Choi, Sang-Mook;Han, Soo-Boo
    • Journal of Periodontal and Implant Science
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    • v.32 no.4
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    • pp.857-864
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    • 2002
  • The aim of this study is to investigate the end of filaments of the different toothbrushes in the market through the stereomicroscope and to evaluate the % of rounded-end filaments considered to be acceptable. 9 brands, total 11 type toothbrushes were tested. 2 toothbrushes of each type which is marked as rounded-end filaments were tested. The toothbrushes which are not marked as rounded-end filaments were excluded. The domestic as well as foreign toothbrushes which are familiar to consumers were tested. 2 tufts of each toothbrushes were cut and examined by stereomicroscope using $40{\times}$ magnification. The procedure was carried out with blind-technique, and the digital photographs were taken. Besides the % of rounded-end filaments, total tufts number, material of the tuft, stiffness, and other special characteristics were recorded. By the classification of Silverstone and Featherstone, rounded-end filaments were examined and counted. The results shows that there are different range of rounded-end filaments according to the toothbrush types(17.7%-91.2%). Atman toothbrush has the most rounded-end filaments(91.2%) among the observed toothbrushes, and the Advantage Plus(Ora1-B) has the next(86.75%). E-Clean #411 has the least(17.70%) and E-Clean #410 of the same brand has also low % rounded-end filaments(20.60%). While G.U.M #409(Butler) has 67.90% rounded-end filaments, G.U.M #471 of the Same brand has comparative low 41.83% rounded-end filaments. 4 types of total 11 have the rounded-end filaments over 80%, however other 4 types have under even 50%. Considering that the correct brushing habit with a toothbrush which has rounded-end filaments can protect the gingival injury and tooth abrasion, it is thought that we dentists need to give the correct information about toothbrush to the patients

The Design of Feature Selection Classifier based on Physiological Signal for Emotion Detection (감성판별을 위한 생체신호기반 특징선택 분류기 설계)

  • Lee, JeeEun;Yoo, Sun K.
    • Journal of the Institute of Electronics and Information Engineers
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    • v.50 no.11
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    • pp.206-216
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    • 2013
  • The emotion plays a critical role in human's daily life including learning, action, decision and communication. In this paper, emotion discrimination classifier is designed to reduce system complexity through reduced selection of dominant features from biosignals. The photoplethysmography(PPG), skin temperature, skin conductance, fontal and parietal electroencephalography(EEG) signals were measured during 4 types of movie watching associated with the induction of neutral, sad, fear joy emotions. The genetic algorithm with support vector machine(SVM) based fitness function was designed to determine dominant features among 24 parameters extracted from measured biosignals. It shows maximum classification accuracy of 96.4%, which is 17% higher than that of SVM alone. The minimum error features selected are the mean and NN50 of heart rate variability from PPG signal, the mean of PPG induced pulse transit time, the mean of skin resistance, and ${\delta}$ and ${\beta}$ frequency band powers of parietal EEG. The combination of parietal EEG, PPG, and skin resistance is recommendable in high accuracy instrumentation, while the combinational use of PPG and skin conductance(79% accuracy) is affordable in simplified instrumentation.