• 제목/요약/키워드: Medication Error

검색결과 65건 처리시간 0.022초

천궁(川芎)의 구강투여(口腔投與) 및 약침시술(藥鍼施術)이 흰쥐 MCAO로 유발된 국소뇌허혈(局所腦虛血)에 대(對)한 콜린성 신경보호효과(神經保護效果) 연구(硏究) (Effects of Cnidium of ficinale(CO) extracts through administrated by means of oral and herbal acupuncture method at GB2l acupoint on focal ischemic brain injury induced by MCAO in rats)

  • 김경선;윤대환;홍석;나창수
    • Korean Journal of Acupuncture
    • /
    • 제22권3호
    • /
    • pp.137-156
    • /
    • 2005
  • Objectives : Cnidium officinale(CO) has been used for medication for stroke in the Oriental Medicine. So this study was planned to investigate the effects of CO on the focal ischemia-induced by Middle Cerebral Artery Occlusion(MCAO) in rats Materials and methods : The focal ischemia was induced by MCAO. CO extracts through oral administration and herbal acupuncture at GB2l was carried out during 3 weeks after focal ischemia-induced. Eight-arm radial maze was used for the behavioral task. For the neuroprotective effect of CO, we investigated AchE, ChAT, and NGF-expression by immnohistochemical method. Results : The error rate in the eight-arm radial maze task was significantly decreased in normal group compared to control group on 1-6days, OA-CO1(CO oral administration, 0.8g/kg) group on 1-6days, OA-CO2(CO oral administration, 1.6g/kg) group on 1-3,5,6days, HA-CO1(CO herbal acupuncture, 0.016g/kg) group on 2,3,6days, HA-CO2(CO herbal acupuncture, 0.008g/kg) group on 1-3,5,6days. The rate of correct choice was significantly increased in OA-CO1, HA-CO2. The density of neurons in the hippocampal CA1 was the most increased in OA-CO1, HA-CO1, HA-CO2. The density of ChAT in the hippocampal CA1 was increased in OA-CO1, HA-CO2. The density of ChAT in the hippocampal CA1 was significantly increased in OA-CO1, HA-CO2. The density of NGE in the hippocampal CAI was significantly increased in OA-CO1, OA-CO2, HA-CO2. Conclusions : These results suggest that CO oral administration with 0.8g/kg and CO herbal acupuncture with 0.008g/kg might be used as a regulator of cell death of cholinergic system induced by stroke.

  • PDF

심정격(心正格)의 보혈(補穴), 신정격(腎正格)의 보혈(補穴), 심정격(心正格)의 보혈(補穴) 배신정격(配腎正格)의 보혈(補穴) 및 심정격(心正格) 자침(刺鍼)이 실험적(實驗的) 뇌허혈(腦虛血)에 미치는 영향(影響) (The Effects of Reinforcing Acupoint of Heart JEONGGYEOK, Reinforcing Acupoint of Kidney JEONGGYEOK, Combination of Reinforcing Acupoint of Heart JEONGGYEOK and Kidney JEONGGYEOK, Reinforcing and Reducing Acupoint of Heart JEONGGYEOK on Focal Ischemia Induced by Inserted Intraluminal Filament in MCA of Rats)

  • 황문현;윤대환;나창수
    • Korean Journal of Acupuncture
    • /
    • 제22권4호
    • /
    • pp.43-56
    • /
    • 2005
  • Objectives : The acupuncture has been used as treatment of disease in the oriental medicine. In this study, it was investigated at had an effects of Heart JEONGGYEOK(心正格) of SAAM five evolutive phase acupuncture techniques(舍岩五行鑛法) for appling deficiency in the heart induced by experimental focal ischemia. Materials and methods : The focal ischemia was induced by middle cerebral artery occlusion for 2hours. The groups divided into 6 groups, normal(intactness group), control(no therapy group after ischemia-induced), AT1(reinforcing acupoint of Heart JEONGGYEOK : acupuncture therapy group at LR1, HT9 after ischemia-induced), AT2(reinforcing acupoint of Kidney JEONGGYEOK : acupuncture therapy group at LU8, KI7 after ischemia-induced) AT3(combination of reinforcing acupoint of Heart JEONGGYEOK and Kidney JEONGGYEOK : acupuncture therapy group at LR1, HT9, LU8, KI7 after ischemia-induced) AT4(reinforcing and reducing acupoint of Heart JEONGGYEOK : acupuncture therapy group at LR1, HT9, HT3, KI10 after ischemia-induced), AT4(reinforcing and reducing acupoint of Heart JEONGGYEOK : acupuncture therapy group at LRI, HT9, HT3, KI10 after ischemia-induced). Acupuncture therapy was carried out during 3 weeks after focal ischemia-induced. Eight-arm radial maze was used for the behavioral task and neuropretective effect of acupuncture therapy was observed by Cresyl violet, AchE, ChAT-stain. Results : The error rate in the eight-arm radial maze task was significantly decreased in AT3 group on 3days, in AT1 and AT4 groups on 4days, in AT3 and AT4 groups on 5days compared to the control group. The rate of correct choice was significantly increased AT4 group compared to the control group. The density of neurons in the hippocampal CA1 were significantly increased in all experiment groups, AT1, AT2, AT3 and AT4 groups compared to the control group. The density of AchE in the hippocampal CA1 was significantly increased in AT4 group compared to the control group. The density of ChAT in the hippocampal CA1 were significantly increased in AT1 and AT3 group compared to the control group. Conclusions : These results suggest that reinforcing and reducing acupoint of Heart JEONGGYEOK could be used as a medication for controlling the stroke by deficiency in the heart.

  • PDF

Management of asymptomatic to mild COVID-19 patients with Cheongpebaedok-tang on the telemedical basis: A retrospective observational case series

  • Sung-Woo Kang;Kwan-Il Kim;Mideok Song;Jinhwan Roh;Namhun Cho;Heung Ko;Sung-Se Son;Minjeong Jeong;Jun-Yong Choi;Ojin Kwon;Seojung Ha;Hee-Jae Jung;Beom-Joon Lee
    • 대한한의학회지
    • /
    • 제44권4호
    • /
    • pp.41-58
    • /
    • 2023
  • Objectives: This retrospective observational study aimed to investigate the efficacy and safety of Cheongpebaedok-tang, a traditional Korean herbal medicine, provided via telemedicine to patients with asymptomatic to mild COVID-19 in Korea. Methods: From February to April 2020, a retrospective analysis investigated COVID-19 patients treated via Korean telemedicine. The study involved asymptomatic to mild cases receiving Cheongpebaedok-tang more than three times, along with continuous Korean medicine care in convalescence. Diagnoses and treatment adhered to the telemedicine guidelines of the Association of Korean Medicine, with varied Cheongpebaedok-tang prescriptions based on symptom severity. Symptom evaluation involved a detailed assessment using a 15-item tool at initial and final sessions. Results: The study included 27 patients, with a mean age of 48.7 ± 2.3 years (mean ± standard error). Patients began self-administering oral Cheongpebaedok-tang for an average of 19.4 ± 1.8 days after the date of COVID-19 diagnosis confirmation and continued the medication for 15.8 ± 1.2 days. The reported side effects of the Cheongpebaedok-tang included palpitations (11.1%), insomnia (7.4%), dizziness (3.7%), and diarrhea (3.7%). All side effects disappeared after adjusting the prescription according to standard treatment guidelines. The occurrence of all COVID-19-related adverse symptoms, except fatigue and myalgia, decreased. Fatigue was the most common chronic symptom persisting after 6 months (51.9%), followed by ocular symptoms (37.0%) and sore throat (22.2%). Conclusions: This study implies Cheongpebaedok-tang may offer a potentially safe, symptom-alleviating approach for managing mild COVID-19 cases via telemedicine, although further comprehensive research is warranted.

핵의학과 내에서의 효과적인 고객위험관리: 위험관리 응대 MOT 개발적용 및 홍보동영상 제작 (Effective Customer Risk Management at the Nuclear Medicine Department: Risk Managemont MOT Development Application and Producing Public Relations Film)

  • 함종훈;황재봉;김준호;이귀원
    • 핵의학기술
    • /
    • 제13권3호
    • /
    • pp.110-122
    • /
    • 2009
  • 목적: 최근 의료기관평가제도는 의료의 질에 대한 병원들의 관심을 높게 하고 그것을 향상시키기 위한 활동을 활발히 전개하고 있다. 또한 추가된 항목인 환자의 위험관리에 대해서도 많은 관심을 보이고 있다. 의정부성모병원 핵의학과는 2008년도 PET/CT도입으로 시작된 부서내 리모델링은 과내 구조 및 업무 프로세스에 많은 변화를 가져왔다. 따라서 변경된 구조와 기존의 업무 처리방식은 미처 알지 못하는 위험요인을 내포하게 되었다. 그러므로 영상 검사 과정에서 발생할 수 있는 위험요인을 다각도로 찾고 분석하여, 부서의 특수한 환경에 맞는 위험관리 프로세스와 위험요인 제거업무를 포함한 개선 활동을 목적으로 한다. 실험재료 및 방법: 핵의학과의 새로워진 프로세스를 다각도로 분석하여 첫째, 위험관리 응대메뉴얼을 제작하여 교육후 실제 업무에 적용한다. 결과분석은 전년도 위험사고 발생건수와 개선활동 후 위험사고 발생건수를 비교하였다. 둘째, 위험관리 홍보동영상은 제작 후 검사전 해당 환자에게 상영하였고 그 후 자체 제작된 설문지로 해당 환자 100명에게 만족도 조사를 하였다. 셋째, 위험요소를 개선할 수 있는 시설물 참여형 개선활동을 통해서 위험요소를 제거하였다. 결과: 안전사고 발생건수는 개선활동이후 PET/CT와 감마카메라 영상 검사 모두 검사건수대비 투약오류, 낙상, 충돌 등의 안전사고가 0건으로 조사되었다. 설문조사 결과는 동영상 상영 후 검사진행과정 이해 74%, 불안감해소 81%로 "만족한다"는 결과가 조사되었다. "위험요소에 대해 주의했습니까?" 라는 물음의 경우 PET/CT는 94%, 감마카메라는 89%가 주의했다는 결과로 조사되었다. 개선활동을 통해서 핵의학과내에서의 고객위험관리를 효과적으로 수행할 수 있었다. 결론: 본 개선활동을 통하여 영상 검사 시 산재된 위험요소를 체계적으로 나열하고 분석하는 계기가 되었다. 또한 안전사고에 대처하는 방사선사의 업무방법에서도 기준이 되는 응대메뉴얼을 적용시킨다면 안전사고의 최소화와 안전사고시 체계적인 피드백이 가능함을 알 수 있었다. 위험요소를 알려주는 방법론적인 부분에서도 일상생활에서 쉽게 접할 수 있는 시청각자료로 제공 되었을 때 보다 효과적이였다. 따라서 이런 활동이 지속적이고 세부화 된 업그레이드 작업을 통해서 환자들에게 제작되어 제공된다면 핵의학 검사 이용의 안전성과 편리성에 도움을 줄 수 있으리라 생각된다.

  • PDF

뇌졸중(腦卒中)에 대(大)한 한방치료법(韓方治療法) 연구(硏究)(증치의학(證治醫學)과 사상의학(四象醫學)) 및 한방(韓方), 양방(洋方), 양(洋)·한방(韓方) 협진치료(協診治療) 효과(效果)에 관(關)한 연구(硏究) (The Study on the investigation of oriental medical theraphy(oriental medical theraphy by symptoms and signs and Sasang constitutional medicine)and the each effect of oriental medicine, occidental medicine and both joint control)

  • 김종원;김영균;김법영;이인선;이인선;장경전;권정남;이원외;송창원;박동일
    • 사상체질의학회지
    • /
    • 제10권2호
    • /
    • pp.351-429
    • /
    • 1998
  • The Purpose of Study 1. Inspection of clinical application on TCD to CVA 2. Objective Comparement and analysis about treatment effect of Western-Medicine, Korean Medicine, Cooperative consultation of Korean and Western medicice for CVA The Subject of Study We intended for the eighty six patient of CVA who had been treated in the Oriental Medical Hospital at Dong Eui Medical Center from 1997. 8. I to 1998. 7. 31 1. View of CT, MRI : the patient of Cb infarction 2. Attack Time : The patient who coming hospital falling ill within the early one week The method of study 1. Treat four group of Korean medicine, Constitution medicine, Western medicine, cooperative consultation of Korean medicine and Western medicine. 2. Application of TCD Check the result for three times, immediatly after the attack, two months later, four months later 3. Comparative analysis of each treatment effect by clinical symptoms and pathologic examination 4. The Judgement of the patient The Result From 8/1/1997 to 7/31/1998, We have the following result by clinical analysis intended for CVA 86 patients who had been treated in the Oriental Medical Hospital at Dong Eui Medical Center from 1997. 8. 1 to 1998. 7. 31 in 1. Analysis according to Age The first stage of thirties, forties, seventies is heavier than forties, fifties in improvement and Index of improvement of symptom 2. Analysis according to sex We have no special relation in an average of symptom and improvement, Index improvement 3. Analysis according to Family History We have the better result in first stage and improvement, index improvement when no family history. 4. Analysis according to Past History We have no special relation in past history like hypertension, DM, heart problem 5. Analysis devided two group, above group and under group on the basis of the average in first stage of all patient. We have the better result when the first stage is light, that the first score of barthel index and CNS is high. 6. Analysis of the effect of treatment about Korean medical treatment, Western medical treatment, cooperative treatment. In this study, the highest group of rate of treatment at four contrast groups (Korean medicine, Constitution medicine, Western medicine, cooperative treatment according to dyagnosis and range of treatment was the patient group of doing dyagnosis and method of treatment based on constitution medicine theory. This is that of doing demostation, A-Tx, po-herb-medication according to dyagnosis and treat method of constitution of Lee Je-ma In case of left, the case of dyagnosis any disease according to doctor view but, normal in TCDwas 22-beginning of attack, 20- two weeks later, 11 case-four weeks later in case of right, 15-beginning of attack, 12-two weeks later, 9 case four weeks later. So left vessel compares to right vessel is more interference, in fact more than a 1/2 of the patients of MCA disease can't do dyagnosis. In rate of imparement, the state of pacient improved but there isn't the improved case of result in TCD. 7. In TCD dyagnosis, between the case of inconsus the doctor view specially MCA in brain blood vessel is in large numbers and in total 86's patient, impossible case of dyagnosis according to interferiance of temporal is 21 case. 7. Result study about application of Kreaan medical treatment 1) The impossible patient of observation MCA blood vescular for interference temporal bone happened in large numbers. 2) There is the case having difference result to CT,MRI, MRA result. 3) Because individual difference is large, excluding to ananalogy of symptom. This is normal numerical value that has possibility of being checked as abnormal numerical value 4) there are a lot of cases that the speed of normal part is as similarly measured as that of abnormal part. It means that we cannot judge the disease by this measure 5) It is rare that this measure represent degree of improvement in patient's condition of disease. When we observe patient's condition become better, but we have no case that the result of TCD test better. 6) The result could be appear differently by the technique of the tester or by the experience of the tester 7) In the TCD test, abnormal symptoms is checked at 0 week, but at 2th week, normal symptoms is checked, again at 4th week abnormal is checked. According to the above result, CVA diagnosis is difficult only with TCD, as it appear in diagnosis error check which is suggested in the problem connected to project, for the aged persons who have the worst hardening of part of the cranium (1998. 5. 26 77 of 83 patients is 50s) there is a lot of cases that the measurement is impossible by TCD and the correction of measurement numerical value is decreased, as the age of cerebral infarction is high, TCD is inappropriate to diagnosis equipment through this study.

  • PDF