• Journal of Korean Medical classics
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• v.12 no.2
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• pp.294-315
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• 1999

$\ll$靈樞 動輸$\gg$ explains the way that the Arm Greater um Lung meridian, the Leg lesser urn kidney meridian and the Leg Yang-Myong Stomach meridian are keeping incessant pulsation, and the relation that these three meridians transport ant irrigate around the whole body. And also, when the meridian lines have been obstructed, the ki travels via shortcuts, in the course of spreading outer ki and inner ki around the whole body. Concretely speaking, in the first mapter it is explained the way that the Arm Greater urn Lung meridian pulses incessantly, in the second chapter, it is explained the way that the Leg Yang-Myong stomach meridian pulses incessantly, in the third chapter, the Leg Lesser urn kidney meridian pulses incessantly and in the fourth chapter, the movement of inner and outer ki are explained. But this chapter has many ancient letters and many parts omitted, so it is too hard to understand directly. Therefore we set to work with the view of helping to understand the original text more accurately by the reference of several editions and many commentarists' fruitful researches.

• Journal of Korean Medical classics
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• v.27 no.3
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• pp.67-86
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• 2014

Objectives : In this study, I want to work on efficacious porridges through inquiry into the Jukmiryu(粥穈類) based on the classical literature. It is intended to serve as a basic study to explore the modern-day application of dishes that are good as patient meals or healthy foods for elderly people. Methods : I have taken the original text of Jukmiryu(粥穈類) included in Junsaengpaljeon(遵生八牋) and translated it. Further, I have compared it to those porridges treated in Nonohangeon (老老恒言), a book in geriatrics from Ming Dynasty. Results : Nonohangeon(老老恒言) describes sources and effects of 100 porridges. With recipes too simplified, however, it doesn't provide any practical help. In contrast, Junsaengpaljeon(遵生八牋) presents 40 porridges together with their effects and recipes. It is practically more beneficial, as it provides recipes more specific than Nonohangeon(老老恒言). Conclusions : Jukmiryu(粥穈類) in Junsaengpaljeon(遵生八牋) set great store on the pharmacological effects of food. As it provides detailed description of porridge recipes and ingredients as well as their effects, readers can easily apply them to symptoms. Since individuals may choose what would be appropriate for their own symptoms, it could be helpful in not only providing patient meals and foods for elderly people but also improving dietary practice.

• Interdisciplinary Bio Central
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• v.2 no.2
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• pp.2.1-2.4
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• 2010

Complex diseases, such as stroke and cancer, have two or more genetic influences and are affected by environmental factors, which complicate them. Due to the complex characteristics of these diseases, we must search and study comprehensive literature-based article resources. Some disease-related literature databases have been developed through specialized journal issues or major websites. Most of them, however, are scattered throughout a website, and users encounter difficulties in finding accurate and comprehensive information easily and quickly. We developed StrokeMed, an integrated literature database for stroke and the differentiation of stroke syndrome. The system allows users to explore PubMed search results, categorized by MeSH (Medical Subject Headings), and the differentiation of stroke syndrome in Oriental medicine. StrokeMed collects data from important sites, such as PubMed, Scirus, and Scopus, automatically to maintain higher-quality and updated content. Currently, the system indexes more than 20,000 PubMed abstracts that are related to stroke, stroke etiology, and Oriental medicine. The system provides valuable literature information to the scientific and medical fields in stroke.

• Journal of Microbiology and Biotechnology
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• v.28 no.3
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• pp.454-464
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• 2018

Salivary microbiota alterations can correlate with dental caries development in children, and mechanisms mediating this association need to be studied in further detail. Our study explored salivary microbiota shifts in children and their association with the incidence of dental caries with dentine involvement. Salivary samples were collected from children with caries and their subsequently matched caries-free controls before and after caries development. The microbiota was analyzed by 16S rRNA gene-based high-throughput sequencing. The salivary microbiota was more diverse in caries-free subjects than in those with dental caries with dentine involvement (DC). Although both groups exhibited similar shifts in microbiota composition, an association with caries was found by function prediction. Analysis of potential microbiome functions revealed that Granulicatella, Streptococcus, Bulleidia, and Staphylococcus in the DC group could be associated with the bacterial invasion of epithelial cells, phosphotransferase system, and ${\text\tiny{D}}-alanine$ metabolism, whereas Neisseria, Lautropia, and Leptotrichia in caries-free subjects could be associated with bacterial motility protein genes, linoleic acid metabolism, and flavonoid biosynthesis, suggesting that functional differences in the salivary microbiota may be associated with caries formation. These results expand the current understanding of the functional significance of the salivary microbiome in caries development, and may facilitate the identification of novel biomarkers and treatment targets.

• The Journal of Korean Obstetrics and Gynecology
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• v.20 no.2
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• pp.25-42
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• 2007

Purpose : Uterine leiomyoma (fibroids) are benign smooth muscle tumors originating from the myometrium. These benign neoplasms of monoclonal origin are typically diagnosed during the reproductive years, occurring only after puberty and tending to regress after menopause. In the present study we used Chiljehyangbu-hwan to determine its growth inhibitory effect and apoptosis in human uterine leiomyoma cells. Methods : Primary cultured human uterine leiomyoma cells were treated with Chiljehyangbu-hwan. Cell viability analysis was analyzed by MTS assay and FACS was performed to ascertain the effects Chiljehyangbu-hwan. DNA fragmentation analysis and casapase-3 activity test were done. Expression of apoptosis related proteins were evaluated by Western blot analysis. Results : Cell viability was significantly influenced by Chiljehyangbu-hwan treatment in a dose-dependent manner in leiomyoma cells compare to normal myometrial cells. FACS showed that Chiljehyangbu-hwan induced Sub G1 arrest. DNA fragmentation assay was carried out and apoptosis was detected. Activation of caspase-3, down-regulation of Bcl-2, with concomitant increased expression in Bid and Bax were observed. Chiljehyangbu-hwan treatment of uterine leiomyoma cells resulted in a concentration-dependent cell death induced via the mitochondrial pathway.

• Korean Journal of Oriental Medicine
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• v.8 no.2 s.9
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• pp.17-22
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• 2002

The Purpose of this study was to find the characteristics of the medicine mainly using the Hyangyak(鄕藥) in the early Chosun by analyzing the text in ${\ulcorner}$Hyangyakjipseongbang(鄕藥集成方)${\lrcorner}$ and comparing it with other medical books. To start out this grand investigation, the research was focused on ${\ulcorner}$Sanghanmun(傷寒門)${\lrcorner}$, Vol.5-8 of ${\ulcorner}Hyangyakjipseongbangs{\lrcorner}$. The conclusion made in this study is as follows: 1. All of the prescriptions in ${\ulcorner}Sanghanmun{\lrcorner}$, was made up of the Hangyak listed in ${\ulcorner}$HyangyakBoncho(鄕藥本草)${\lrcorner}$, Vol.76-85 of ${\ulcorner}Hyangyakjipseongbangs{\lrcorner}$ 2. The main purpose of ${\ulcorner}Sanghanmun{\lrcorner}$ was to make sure it was easy to use for people with no medical backgrounds. To have a more specific understanding on the medicine mainly llsing the Hyangyak, further research should be done on how the catergory of the Hangyak changed. This should be done by comparing the books written after the ${\ulcorner}Hyangyakjipseongbangs{\lrcorner}$, and also on the characteristics of the usage of prescriptions in ${\ulcorner}Hyangyakjipseongbangs{\lrcorner}$.

• Journal of the Korean Institute of Oriental Medical Informatics
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• v.18 no.1
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• pp.1-63
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• 2012

Objective : "Huatuoxuanmenneizhaotu" is a Huatuo's about 5~6 century works are estimated to be voted for. Scored the first Anatomical Pictures. Expand your knowledge on the anatomy of the later set the foundation. This books is part of two volumes, which is largely divided into six parts. We have concern on the content and features. Method : Through "Huatuoxuanmenneizhaotu" text translation, we will try to categorize two ways : classifying 1) The first volume of Chapter 1, Pictures 2) The second volume divided into four parts, Chapter 2, Viscera Disease and Chapter 3, Viscera metastasize and Chapter 4, Viscera and Bowel each for metastasize, explained. Result : In consideration against Disease symptom classification, Medicine classification, processing of medicinals examine. Viscera Disease symptom each wind pattern(風證), qi pattern(氣證), heat pattern(熱證), cold pattern(冷證), deficiency pattern(虛證) was classified as. Same method were explained as Viscera into Viscera, as Viscera into Bowel. Viscera Disease also not mentioned in the Bowel Disease symptoms were found to be viewed. Conclusion : These results explain "HuatuoXuanmenNeizhaotu" were really diverse and various.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.12
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• pp.5165-5172
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• 2016

Background: Stomach cancer is one of the five most common cancers in Iran. This study examined the effectiveness of a mobile telephone short-message service (SMS) based-education intervention using Health Belief Model (HBM) variables in improving dietary behavior in terms of stomach cancer prevention among a sample of Iranian female college students. Materials and Methods: In this quasi-experimental study, 124 female college students in the dormitories of Yazd University, Yazd, Iran were randomly selected and assigned to either the intervention (n=62) or the control group (n=62). Information (data) regarding HBM variables and dietary behavior related to stomach cancer prevention was collected by a self-administrated questionnaire. Forty eight messages were designed and sent to the participants' phones in the intervention group during the 48-day intervention period. Two groups were followed-up one month after the intervention delivered via SMS. Results: There were significant differences in HBM variables (except for the perceived severity) and the preventive dietary behaviors for stomach cancer in the intervention group compared to the comparison group following the education intervention delivered via SMS. Conclusions: SMS-delivered nutrition education intervention can be a practical strategy to improve dietary behavior related to stomach cancer prevention.

• Asian Oncology Nursing
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• v.12 no.3
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• pp.237-245
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• 2012

Purpose: The purpose of this study was to identify attributes of the concept of cancer survivorship. Methods: Walker & Avant's concept analysis framework (2005) was used to review the medical & nursing text books, medical and nursing research articles related to cancer survivorship and published from 1985 to 2011. Results: There were nine aspects of the concept of cancer survivorship: A process, liminality, uncertainty, life-changing experience, complexity, unique experience, duality of positive and negative aspects, partnership, and need for support. Antecedents of cancer survivorship were cancer diagnosis and perception as a cancer survivor. Empirical referents of cancer survivorship were survival rate, quality of life, adaptation to the survivorship experience, and health-related hardiness, social support, spirituality, and health behavior. The consequences of cancer survivorship were effects on the physical, psychosocial, spiritual and socio-economic well-being of the patients. Conclusion: This concept analysis of cancer survivorship is expected to contribute to promotion of survivorship care in the clinical field by removing conceptual ambiguity and confirming the true meaning of survivorship care.

• Journal of Korean Medical classics
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• v.25 no.1
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• pp.117-139
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• 2012

Objective : In this study, I would like to emphasize the importance of context in studying quoted verses in "Donguisusebowon". Method : First, methodology applied in researches on "Donguisusebowon" quotations were organized. Next, in order to examine the effects of the aforementioned methodology, several quoted verses were approached in such method. Result : First, the verse, 'In cases of Dry-Feces(大便秘燥), Rheum undulatum Linne(大黃) could be used in the medicinal formulas and treatment, but not Croton tiglium Linne(巴豆)'. In the texts of Shanghanlun(傷寒論), Zhang, Zhongjing(張仲景) prescribed Sammulbaeksan(三物白散) in treating 'Gyeolhyung due to Excessive cold'(寒實結胸), which includes Croton tiglium Linne(巴豆). From this, we can see that Lee, jema's statement in "Donguisusebowon" is false. Conclusion : Lee, jema's mistake was that he accepted Shanghanlun(傷寒論) as quoted in "Donguibogam", instead of the original text, accidently quoting Heo, jun's source of reference.