• Title/Summary/Keyword: Medical radiation

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Running of high patient volume radiation oncology department during COVID-19 crisis in India: our institutional strategy

  • Gupta, Manoj;Ahuja, Rachit;Gupta, Sweety;Joseph, Deepa;Pasricha, Rajesh;Verma, Swati;Pandey, Laxman
    • Radiation Oncology Journal
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    • v.38 no.2
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    • pp.93-98
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    • 2020
  • Purpose: Due to COVID 19 pandemic, the treatment of cancer patients has become a dilemma for every oncologist. Cancer patients are at an increased risk of immunosuppression and have a higher risk to acquire any infection. There are individual experiences from some centers regarding the management of cancer patients during such a crisis. So we have developed our institutional strategy to balance between COVID and cancer management. Materials and Methods: Radiation Oncology departmental meeting was held to prepare a consensus document on Radiotherapy schedules and department functioning during this pandemic. Results: Strategies were taken in form of following areas were steps need to be taken to decrease risk of infection, categorise treatment on the basis of priority, radiotherapy schedules modification, academic meetings and management of COVID positive patient/personnel in Radiation Oncology department. Conclusion: We hope to strike the balance in overcoming both the battles and emerge as winners. Stringent long term follow up will be done for assessing the response or any unforeseen treatment related sequelae.

Study of Radiation Safety Management of Veterinary Hospital in Korea (동물병원 방사선 안전관리체계에 대한 연구)

  • Chae, Soo-young;Choi, Ho-jung;Lee, Young-won
    • Journal of Veterinary Clinics
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    • v.37 no.1
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    • pp.15-22
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    • 2020
  • This study investigated the effectiveness of radiation safety rules in animal hospital and the awareness and behavior of veterinary radiation workers. With the questionnaires, the data was collected from randomly selected veterinarians in animal hospitals and animal medical imaging centers. Collected data were about radiation device, shielding device, regulations, safety management, education, knowledge, behavior and awareness. Frequency, correlation and multiple regression analysis were performed. The medical devices related with radiation in animal hospital were X-ray (59%), CT (15%), fluoroscopy (12%), mobile X-ray (12%) and others (2%). The number of people using radiation shielding device is high. The answers were low on knowing radiation related regulation and receiving radiation protection education. The group with higher knowledge and awareness shows positive correlation with safety behavior. The increase of use of the radiation related medical devices in veterinary hospital causes the increase of radiation exposure risk. This study suggests that radiation safety management system and policies need to be developed to protect radiation workers and give them correct information and consciousness.

Organ Specific Gene Expressions in C57BL6 Mice

  • Majumder, Zahidur Rahman;Lee, Woo-Jung;Kim, Dae-Yong;Jeoung, Doo-Il;Cho, Chul-Koo;Lee, Su-Jae;Bae, Sang-Woo;Lee, Yun-Sil
    • Proceedings of the Korean Nuclear Society Conference
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    • 2004.10a
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    • pp.1211-1211
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    • 2004
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Acute Radiation Syndrome in an Irradiated Minipig Model for Patients with Radiation Exposure

  • Jang, Hyosun;Kim, Joong-sun;Shim, Sehwan;Jang, Won-seok;Lee, Sun-Joo;Myung, Jae Kyung;Lee, Seung-Sook;Park, Sunhoo
    • Journal of Radiation Protection and Research
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    • v.42 no.3
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    • pp.146-153
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    • 2017
  • Background: Acute radiation syndrome (ARS) primarily refers to damage to the hematopoietic system, myeloid system, and gastrointestinal (GI) system caused by radiation exposure. Such damage progresses to become life-threatening. In particular, as the syndrome develops very rapidly-within several hours from radiation exposure-prompt and accurate diagnosis and treatment are needed, as is further research into appropriate diagnostic and treatment modalities. Materials and Methods: Minipigs, which display human-like properties, underwent whole-body irradiation at 2 or 4 Gy (doses causing hematopoietic ARS) or at higher doses of 7 or 12 Gy. Changes in the blood cells and clinical symptoms were analyzed and we performed a necropsy when the animals succumbed to ARS. Results and Discussion: The minipig irradiated with 2 Gy showed a decrease in white blood cells, including neutrophils, lymphocytes, and platelets in the early stages. However, the blood cell counts gradually increased and returned to normal values. The minipig irradiated with 4 Gy succumbed due to hematopoietic ARS. In contrast, the minipigs irradiated with 7 or 12 Gy exhibited clinical symptoms of combined GI damage and hematopoietic syndrome. Moreover, a characteristic pattern of platelet changes was observed in the 7 and 12 Gy irradiated minipigs. Conclusion: The changes in the platelet count caused by radiation exposure observed in minipigs, which are hematologically and pathohistologically similar to humans, suggest that they can be used as a novel diagnostic criterion.