• 전자공학회논문지C
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• 제36C권12호
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• pp.90-97
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• 1999

최근에 컴퓨터를 이용한 영상처리기술 및 고속통신망의 발달과 더불어 하드웨어의 고성능화로 의학분야에서 발생되는 영상들에 대해 분석 및 처리를 자동화하려는 많은 연구가 진행되고 있다. 본 논문에서는 말초혈액영상에서 혈구세포들을 자동으로 분석, 분류 및 카운트하기 위해 다층신경망에 기반한 시스템을 설계 및 구현하였다. 이를 위해 먼저 CDD 카메라가 부착된 현미경으로부터 영상을 입력받아 적혈구와 백혈구 분류를 위한 다양한 특징추출 알고리즘을 적용하였다. 또한, PCA를 적용해 다차원의 특징을 저차원으로 줄여 분류기의 훈련과 인식 시간을 단축시킴으로서 보다 효율적인 분류기 시스템을 구축하였다. 따라서 , 본 논문에서는 제안된 시스템이 실제 임상 병리진단 가이드 시스템에 적용 가능함을 보일 수 있었다.

• 한국빅데이터학회지
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• 제4권2호
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• pp.195-205
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• 2019

LOD(Linked Open Data)는 데이터 공개방식 중에서 가장 우수한 수준으로 평가받고 있으며, 인터넷 상에서 서로 관련있는 데이터를 표준방식으로 연결하여 하나의 거대한 데이터베이스처럼 검색할 수 있도록 한다. 글로벌 환경에서 관련있는 데이터들이 LOD 형태로 구축되는 사례가 증가하고 있으나 국내 보건의료 분야에서 LOD 형태의 데이터 공개는 아직 초보적인 수준에 머물러 있다. 본 논문에서는 한국의학연구논문 데이터와 보건의료 빅데이터 연계 플랫폼 데이터를 중심으로 국내외 관련있는 DB들을 LOD 방식으로 연계하여 서비스하는 LOD 플랫폼 구축사례를 소개한다. 각 DB의 모든 데이터를 LOD로 연계하는 것은 시간과 노력이 많이 필요하며, 기본적으로 민간보다 국가나 공공기관이 담당해야 하는 인프라성 연구이다. 본 연구에서는 각 DB의 일부만을 대상으로 하여 LOD국내외 10개 사이트를 연계하였으며, 이를 통해 사용자는 편리한 방식으로 국내외 여러 기관의 데이터를 연계하여 검색할 수 있게 된다.

• 보건행정학회지
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• 제26권2호
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• pp.107-114
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• 2016

Background: Over the last few decades, because hospitals in South Korea also have undergone dramatic changes, Korean hospitals traditionally have provided specialized health care services in the health care market. Inner Herfindahl-Hirschman Index (IHI) measures hospital caseloads based on patient proportions, independent of patient volumes. However, IHI that rely solely on patient proportions might be problematic for larger hospitals that provide a high number of diagnosis categories, as the patient proportions in each category are naturally relatively smaller in such hospitals. Therefore, recently developed novel measure, category medical specialization (CMS) is based on patient volumes as well as patient proportions. Methods: We examine the distribution of hospital specialization score by hospital size and investigate association between each hospital specialization and length of stay per case and hospital cost per case using Korean National Health Insurance Service-cohort sample data from 2002 to 2013. Results: Our results show that IHI show a decreasing trend according to the number of beds and hospital type but CMS show an increasing trend according to the number of beds and hospital type. Further, inpatients admitted at hospitals with higher IHI and CMS had a shorter length of stay per case (IHI: B=-0.104, p<0.0001; CMS: B=-0.044, p=0.001) and inpatients admitted at hospitals with higher IHI and CMS had a shorter hospital cost per case (IHI: B=-0.110, p=0.002; CMS: B=-0.118, p=<0.0001). Conclusion: This study may help hospital policymakers and hospital administrators to understand the effects of hospital specialization strategy on hospital performance under recent changes in the Korean health care environment.

• Asian Pacific Journal of Cancer Prevention
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• 제17권7호
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• pp.3173-3177
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• 2016

Background: The Ministry of Public Health (MOPH) in Lebanon provides cancer drugs free of charge for uninsured patients who account for more than half the total case-load. Other categories of cancer care are subsidized under more stringent eligibility criteria. MOPH's large database offers an excellent opportunity to analyze the cost of cancer treatment in Lebanon. Materials and Methods: Using utilization and spending data accumulated at MOPH during 2008-2013, the cost to the public budget of cancer drugs was assessed per case and per drug type. Results: The average annual cost of cancer drugs was 6,475$ per patient. Total cancer drug costs were highest for breast cancer, followed by chronic myeloid leukemia (CML), colorectal cancer, lung cancer, and Non-Hodgkin's lymphoma (NHL), which together represented 74% of total MOPH cancer drug expenditure. The annual average cancer drug cost per case was highest for CML ($31,037), followed by NHL ($11,566). Trastuzumab represented 26% and Imatinib 15% of total MOPH cancer drug expenditure over six years. Conclusions: Sustained increase in cancer drug cost threatens the sustainability of MOPH coverage, so crucial for socially vulnerable citizens. To enhance the bargaining position with pharmaceutical firms for drug cost containment in a small market like Lebanon, drug price comparisons with neighboring countries which have already obtained lower prices may succeed in lowering drug costs.

• Asian Pacific Journal of Cancer Prevention
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• 제15권14호
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• pp.5611-5615
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• 2014

Context: Tobacco is the single largest cause of preventable death among adults globally, as it is in India. Despite this alarming situation, there is very minimal inclusion of tobacco in formal education systems, including the medical discipline, in India. Aims: The present study analyzed the extent of integration of tobacco control related content in Masters of Public Health (MPH) curricula of various institutes in India. Materials and Methods: This cross-sectional study was conducted during January 2011 to May 2011 in all colleges of the country offering a MPH course. The colleges were enlisted using various internet search engines (Google Scholar, Pubmed, Medline), other published literature and snowball technique. A 50 items semi-structured questionnaire was designed, posted and e-mailed (followed by hard copy) to the Person-In-Charge of the MPH program. Statistical Analysis: Descriptive statistics were used to profile the tobacco control content in respective institutions. All data entry and analysis was conducted using SPSS (version 16) for windows. Results: The duration of the MPH course was two years in all institutes and had accreditation with some affiliated body. Tobacco related diseases were covered under 'non communicable diseases' section by every institute. However, a mere 41.4% of institute's had faculty who had received specialized training in tobacco control. More coverage was given to health risks and effects of smoking as compared to cessation interventions (5 A's), symptoms of withdrawal and pharmacological treatments. Only 25% of institutes were in process of introducing tobacco courses into their curricula. Lack of expertise and administrative barriers were cited as perceived major problems in inclusion of tobacco control in MPH curricula. Conclusions: It can be concluded that tobacco control is not receiving adequate attention in public health curricula in India. There is a need for coordinated efforts in the area of tobacco control so as to reduce morbidity and mortality from tobacco induced diseases.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제20권4호
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• pp.300-304
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• 1998

Moderns have desire likely to be further good-looking concomitant with a qualitative advancement of the life. With one of this phenomenon, an orthognathic surgery performing at the dept. of oral and maxillofacial surgery have been becoming a more extensively. It's possible to occur many complications during the operations and especially, an excessive bleeding of those may be fatal and so a transfusion is performing for the prevention &management of that. But, because of the rate of increase of an blood-born infection like AIDS via transfusion, nowadays an autologous blood transfusion is interesting to us. We made a comparative study of an amount of blood loss &transfusion using hemoglobin value after classifying the orthognathic surgeries from Feb. '97 to Mar. '98 in single-jaw and doublejaw surgery. And we intended to set a standard against of a routine preoperative cross-matching deciding the amount of predictive homologous blood transfusion according to operative method. Simultaneously, we studied the realization &effectiveness of autologous blood transfusion with some cases, so would like to present. Results: 1. Single-jaw operation can be performed without blood transfusion or with homologous blood transfusion through only blood typing & screening. 2. We commonly transfuse two units of blood with double-jaw operation and an autologous blood transfusion has much more advantage than an homologous blood transfusion. 3. We can reduce charge associated with blood transfusion through precisely preoperative evaluation of patients and proper type of blood transfusion.

• 대한간호학회지
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• 제41권1호
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• pp.101-109
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• 2011

Purpose: This study was done to comparatively analyze the general education curriculum of 4-yr and 3-yr nursing schools in Korea. Methods: Ten university 4-yr nursing schools were selected based on universities in Korean Accreditation Board of Nursing 2010 or "2009 Korea's Best Universities-Top 10" published by Joong-Ang Daily. Ten college 3-yr nursing schools were selected based on colleges in Korean Accreditation Board of Nursing 2010. Results: 1) Generally 4-yr nursing schools maintained the relationships between organizational philosophy/purposes and subjects in the general education curriculum. But 3-yr nursing schools did not. 2) In 4-yr nursing schools there was a relatively higher credits ratio of general education curriculum and selective courses than in 3-yr nursing schools. 3) In 4-yr nursing schools variety of courses was relatively higher than 3-yr nursing schools. 4) In 4-yr nursing schools, operating conditions were relatively better (number of tenure professors, ratio of professors to students, Identification of exclusive organization in charge of the general education curriculum) for the general education curriculum than 3-yr nursing schools. Conclusion: The results identify significant differences in the general education curriculum of 4-yr and 3-yr nursing schools in Korea, indicating that 3-yr nursing schools should make efforts to improve the good quality of general education curriculum.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2014년도 제46회 동계 정기학술대회 초록집
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• pp.434.2-434.2
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• 2014

We observe enhanced pH response of solution-gated field-effect transistors (SG-FET) having 1D-2D hybrid channel of vertical grown ZnO nanorods grown on CVD graphene (Gr). In recent years, SG-FET based on Gr has received a lot of attention for biochemical sensing applications, because Gr has outstanding properties such as high sensitivity, low detection limit, label-free electrical detection, and so on. However, low-defect CVD Gr has hardly pH responsive due to lack of hydroxyl group on Gr surface. On the other hand, ZnO, consists of stable wurtzite structure, has attracted much interest due to its unique properties and wide range of applications in optoelectronics, biosensors, medical sciences, etc. Especially, ZnO were easily grown as vertical nanorods by hydrothermal method and ZnO nanostructures have higher sensitivity to environments than planar structures due to plentiful hydroxyl group on their surface. We prepared for ZnO nanorods vertically grown on CVD Gr (ZnO nanorods/Gr hybrid channel) and to fabricate SG-FET subsequently. We have analyzed hybrid channel FETs showing transfer characteristics similar to that of pristine Gr FETs and charge neutrality point (CNP) shifts along proton concentration in solution, which can determine pH level of solution. Hybrid channel SG-FET sensors led to increase in pH sensitivity up to 500%, compared to pristine Gr SG-FET sensors. We confirmed plentiful hydroxyl groups on ZnO nanorod surface interact with protons in solution, which causes shifts of CNP. The morphology and electrical characteristics of hybrid channel SG-FET were characterized by FE-SEM and semiconductor parameter analyzer, respectively. Sensitivity and sensing mechanism of ZnO nanorods/Gr hybrid channel FET will be discussed in detail.

• 한국정보통신학회논문지
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• 제17권3호
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• pp.533-539
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• 2013

최근 의료 및 생체공학 분야의 액추에이터(actuator)와 센서 및 연료전지로 활용할 수 있는 새로운 재료인 IPMC(Ionic Polymer Metal Composite)에 대한 관심이 높아지고 있다. 이러한 IPMC의 특징은 센서(sensor)와 액추에이터(actuator)의 성질을 동시에 가지는 있는 특이한 성질을 가진 복합재료로서 IPMC에 전압을 가하면 움직임이 생기며, IPMC에 움직임이 발생하면 IPMC 내부에 전압이 충전되는 성질이 있어 모션 센서나 힘 센서로도 활용할 수 있다. 본 논문에서는 이러한 IPMC에 대한 몇 가지 특성을 파악하고 IT 기술인 스마트폰의 연계하여 원격지에서 IPMC의 동작을 제어할 수 있도록 시스템을 구성하였다. 또한, 스마트폰을 기반으로 하여 영상정보를 전송하여 모니터링 하도록 하였다. IPMC의 동작제어는 스마트폰의 블루투스를 이용하여 동작명령을 전송하도록 시스템을 구현하였다. 본 논문의 실험 및 구현으로부터 IPMC 물성에 대한 정확한 분석은 부족하지만 향후 IPMC의 활용에 있어서 IT 기술과의 융합을 통하여 센서, 액추에이터, 연료전지 등과 같은 분야에 적극 활용할 수 있음을 확인할 수 있었다.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1992년도 추계학술대회
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• pp.97-99
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• 1992

After development of order communication system for out-patients using PC and LAN in May 1992, this system had been tested for 2 months. The system also use Host computer(IBM 9221-170) as a data bank and communicats wi th emulation card(3270 emulator. Interlink Inc., Korea). Since September 1992, this system(named YOUSEI-PC) has been running successfully in the Yonsei Cardiovascular Center of the Severance Hospital, Yonsei University College of Medicine. After introducing this system, it enables patients to receive drugs wi thin 30 minutes after prescription and revealed effective system not to reduce waiting time for the patients but also to remove charge-troubling(due to mis-entry of prescription). This system also seems to be effective in terms of office automatism for hospital management. However users, usually physitions, required more friendly and easy system to operate and we thought that the most important one to successfully introduce order communication computer system in the hospital is user interface.