• Asian Pacific Journal of Cancer Prevention
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• v.15 no.2
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• pp.585-588
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• 2014

Colorectal cancer is one of the most prevalent diseases all over the world. Early screening and start of chemotherapy is effective in decreasing mortality. This type of cancer can be controlled to some extent via a healthy diet rich in fruit and vegetables. Ginseng is a plant which has been consumed as a herbal medicine for thousands of years in Asian countries. Several in vitro and in vivo studies have shown that this plant not only reduces the incidence of colorectal cancer, but also improves patient's status by enhancing the effects of chemotherapy drugs. However, further studies are needed to prove this relationship. We briefly review ginseng and its components such as ginsenosides reported anticancer effects and their mechanisms of action. Understanding these relationships may produce insights into chemical and pharmacological approaches for enhancing the chemo preventive effects of ginsenosides and for developing novel anticancer agents.

• The Korean Journal of Emergency Medical Services
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• v.9 no.1
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• pp.133-144
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• 2005

Purpose : The purpose of this study was to explore the structure and characteristics of job values about senior student of EMT Dept. Method : A Q-methodology was used to identify factors in job values. A Q-sample was collected from in-depth and objective interviews and literature reviews. A P-sample was composed of 31 EMT students. Result : Results revealed three factors; Self achievement-oriented, stability-oriented, and aptitude-oriented. The 'self achievement-oriented' factor was characterized by preference of achievement, worth, and activity in choosing occupation. The 'stability-oriented' factor was focused on security of retirement age, pay, compensation, and lifelong job. The 'aptitude-oriented' factor was showed aptitude, interesting in choosing occupation. Conclusion : We evaluated that these results was used as useful data for the development of curriculum and guidance of choosing occupation.

• The Korean Journal of Pain
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• v.31 no.1
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• pp.58-59
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• 2018

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.17
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• pp.7795-7801
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• 2015

The aim of the present research was to establish primary characteristics of electron beams for a Varian 2100C/D linear accelerator with recently developed PRIMO Monte Carlo software and to verify relations between electron energy and dose distribution. To maintain conformity of simulated and measured dose curves within 1%/1mm, mean energy, Full Width at Half Maximum (FWHM) of energy and focal spot FWHM of initial beam were changed iteratively. Mean and most probable energies were extracted from validated phase spaces and compared with related empirical equation results. To explain the importance of correct estimation of primary energy on a clinical case, computed tomography images of a thorax phantom were imported in PRIMO. Dose distributions and dose volume histogram (DVH) curves were compared between validated and artificial cases with overestimated energy. Initial mean energies were obtained of 6.68, 9.73, 13.2 and 16.4 MeV for 6, 9, 12 and 15 nominal energies, respectively. Energy FWHM reduced with increase in energy. Three mm focal spot FWHM for 9 MeV and 4 mm for other energies made proper matches of simulated and measured profiles. In addition, the maximum difference of calculated mean electrons energy at the phantom surface with empirical equation was 2.2 percent. Finally, clear differences in DVH curves of validated and artificial energy were observed as heterogeneity indexes were 0.15 for 7.21 MeV and 0.25 for 6.68 MeV. The Monte Carlo model presented in PRIMO for Varian 2100 CD was precisely validated. IAEA polynomial equations estimated mean energy more accurately than a known linear one. Small displacement of R50 changed DVH curves and homogeneity indexes. PRIMO is a user-friendly software which has suitable capabilities to calculate dose distribution in water phantoms or computerized tomographic volumes accurately.

• Korean Medical Education Review
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• v.20 no.1
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• pp.32-43
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• 2018

Although student research programs have been implemented worldwide, research programs during premedical school have unique characteristics. The purpose of this study is to evaluate factors that influence the effects of premedical school research programs. Eighty second-year premedical students at Pusan National University were included in the study. Effect elements and influential factors were extracted through reference reviews and in-depth individual interviews. A Likert scale questionnaire was developed using the extracted elements and factors, and Cronbach's alpha coefficient was used to analyze the reliability of the survey. The mean value and the standard deviation for each question were calculated to evaluate education effectiveness and learning satisfaction, and the influence of each factor on effect was analyzed using correlation analysis. Students' research skills and knowledge were improved in the short term; however, interest in research or in a career as a researcher did not increase. Student interest, participation, and contributions were important factors. Among professors, passion, considerateness, and teaching method including the level of lesson were influential factors. Implementation of curriculum and support and guidance were influential as well, whereas evaluation system was not a factor. To improve student research programs, several factors that influence education effectiveness and learning satisfaction should be considered.

• Journal of Preventive Medicine and Public Health
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• v.54 no.3
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• pp.182-189
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• 2021

Objectives: This study investigated the relationship between sleep quality during pregnancy and preterm birth. Methods: This longitudinal study was conducted between August 2018 and May 2019. The participants were 150 pregnant women who had been referred to 7 healthcare centers in the city of Qazvin, Iran and met the inclusion criteria. The Petersburg Sleep Quality Index, the Epworth Sleepiness Scale, and 2 questions about daytime sleep status and a demographic questionnaire were administered at 14-18 weeks and 28-32 weeks of gestation. Data were analyzed using the Mann-Whitney test, the Fisher exact test, and univariate and multivariable logistic regression. Results: In the present study, poor sleep quality affected 84.7% of the participants at 14-18 weeks and 93.3% at 28-32 weeks of gestation. The final model for preterm birth prediction incorporated age and the Petersburg Sleep Quality Index score in the second and third trimesters. Preterm birth increased by 14% with each unit increase in age. With each unit increase in the Petersburg Sleep Quality Index score in the second and third trimesters, preterm birth increased by 42% and 28%, respectively, but the p-values of these factors were not significant. Conclusions: Although a significant percentage of pregnant women had poor sleep quality, no significant relationship was found between sleep quality during pregnancy and preterm birth.

• Archives of Plastic Surgery
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• v.49 no.3
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• pp.462-470
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• 2022

Background Reactive oxygen species cause serious damage to the physiological function of tissues. Determination of total antioxidant capacity of skin tissue is one of the determinants of damaged tissue function. Mast cells (MCs) are one of the groups of cells that are invited to the site of injury. The healing process begins with the rapid release of various types of MCs' intermediate factors at the site of injury. Bone marrow mesenchymal stem cell (BMMSC) production and secretion have been shown to regenerate the skin. The aim of this research was to evaluate the wound-healing and antioxidant effects of BMMSCs per MCs. Methods Fifty-four albino Wistar male rats were divided into three groups: (1) nonsurgery, (2) surgery, and (3) surgery + BMMSCs. Groups 2 and 3 were operated with a 3 × 8 cm flap and in group 3, cell injections (7 × 10⁹ cell injection at the time of surgery) were performed. After days 4, 7, and 15, percentage of the surviving tissue, histological characteristics, superoxide dismutase (SOD) activity, and amount of malondialdehyde (MDA) were measured in the groups. For results, Graph Pad Prism 8 software was used, and data were analyzed and compared by analysis of variance and Tukey test. Results BMMSCs' application decreased the amount of MDA, increased SOD activity and survival rate of the flaps, and improved the histological characteristics. Conclusion This study revealed the protective effects BMMSCs alongside MCs against oxidative stress on the survival of the flaps. However, for clinical use, more research is needed to determine its benefits.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.12 no.12
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• pp.5797-5804
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• 2011

Recently, the medical education is undergoing system transition from a medical college to a medical graduate school and introduction of performance test in the doctor license state examination. Therefore, To deal with these challenges, it is needed that medical faculty prepare the education programs for considering student's personal characteristics and improving Clinical performance. So, The purpose of this study was to understand relation among Stress, ego-resilience, self-efficacy and Clinical performance in graduate medical student, and for this study, We conducted a survey of 97 medical graduate school students in D city during the period from August 19st to 20st. 2011. The study found a negative correlation between Stress and Ego-Resilience, a positive correlation of stress with confidence at low region in Self-Efficacy. Ego-Resilience correlates positively with CPX at low region in Clinical performance, Preference for difficulty level of the task at low region in Self-Efficacy correlates negatively with OSCE. OSCE and CPX at low region in Clinical performance are positively correlated. Therefore, Stress reduction of students can improve Self-Efficacy, Furthermore, improve ultimately Clinical performance. According to this study, To improve Clinical performance competence, student's personal characteristics should be considered and education programs for self-efficacy and ego-resilience advancement be reflected in curriculum.

• The Journal of Korean Medicine
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• v.33 no.1
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• pp.121-135
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• 2012

Objectives: This article describes the effectiveness of, and student satisfaction with, the medical interview course. Methods: In the years 2010 and 2011, forty-two students took the medical interview course at the School of Korean Medicine, Pusan National University. The evaluation of the course was conducted using student questionnaires. Results: The students believed that learning medical interview skills was very helpful, and there was an increase in the number of students who thought they could improve their skills by learning the medical interview course contents. Also, they have come to feel that 'building a relationship' is the most important skill in the medical interview process. We used experiential teaching methods such as doctor-patient role-playing, and the students rated that method better than others. In addition, the students responded that the appropriate time to take a medical interview course is in the middle of a clinical practice. They also thought that the current credit value of the course was appropriate. Moreover, the students wanted to add some specific contents about specialized communication skills for Korean medical treatment. Conclusions: The medical interview course received a favorable evaluation from the students who finished the course. Among the course contents, they were most concerned with building the doctor-patient relationship. Also, they preferred experiential teaching methods more than didactic methods. The current timing and credit value of the medical interview class was evaluated as appropriate, and the students felt that communication skills specific to Korean medical treatment need to be taught. Therefore, we conclude the medical interview course is important and is worth considering as an independent course.

• Korean Medical Education Review
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• v.17 no.1
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• pp.39-48
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• 2015

The purpose of this study was to propose a theoretical model for an integrated medical humanities curriculum based on a STEAM (science, technology, engineering, arts, and mathematics) education framework and to provide a guideline for curriculum integration. Three dimensions of integrated curriculum development are competencies, core contents, and elements of integration. Competencies imply the purpose of the medical humanities of a medical school and the exit outcomes of the curriculum. Core contents imply the goals and objectives of the curriculum. We compared the goals and themes of the medical humanities with core attributes of professionalism. Four elements of integration were proposed: units (cases, problem activities, core contents, disciplines/subjects), types (multidisciplinary, interdisciplinary, transdisciplinary), contexts of integration (life cycle of patients, scope of society), and stages of student development (from student to doctor). It is expected that this theoretical model for an integrated medical humanities curriculum can be used as a guideline for curriculum development and an evaluation criterion for instructional designers and subject matter experts.