• Title/Summary/Keyword: Medical Department

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Evolution of Radiological Treatment Response Assessments for Cancer Immunotherapy: From iRECIST to Radiomics and Artificial Intelligence

  • Nari Kim;Eun Sung Lee;Sang Eun Won;Mihyun Yang;Amy Junghyun Lee;Youngbin Shin;Yousun Ko;Junhee Pyo;Hyo Jung Park;Kyung Won, Kim
    • Korean Journal of Radiology
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    • v.23 no.11
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    • pp.1089-1101
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    • 2022

  • Immunotherapy has revolutionized and opened a new paradigm for cancer treatment. In the era of immunotherapy and molecular targeted therapy, precision medicine has gained emphasis, and an early response assessment is a key element of this approach. Treatment response assessment for immunotherapy is challenging for radiologists because of the rapid development of immunotherapeutic agents, from immune checkpoint inhibitors to chimeric antigen receptor-T cells, with which many radiologists may not be familiar, and the atypical responses to therapy, such as pseudoprogression and hyperprogression. Therefore, new response assessment methods such as immune response assessment, functional/molecular imaging biomarkers, and artificial intelligence (including radiomics and machine learning approaches) have been developed and investigated. Radiologists should be aware of recent trends in immunotherapy development and new response assessment methods.

  • https://doi.org/10.3348/kjr.2022.0225 인용 PDF

The First Living-Donor Lobar Lung Transplantation in Korea: a Case Report

  • Choi, Sehoon;Park, Seung-Il;Lee, Geun Dong;Kim, Hyeong Ryul;Kim, Dong Kwan;Jung, Sung-Ho;Yun, Tae-Jin;Kim, In Ok;Choi, Dae-Kee;Choi, In-Cheol;Song, Jong-Min;Hong, Sang-Bum;Shim, Tae Sun;Jo, Kyung-Wook;Lee, Sang-Oh;Do, Kyung-Hyun;Chae, Eun Jin
    • Journal of Korean Medical Science
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    • v.33 no.43
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    • pp.282.1-282.6
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    • 2018

  • Lung transplantation is the only treatment for end-stage lung disease, but the problem of donor shortage is unresolved issue. Herein, we report the first case of living-donor lobar lung transplantation (LDLLT) in Korea. A 19-year-old woman patient with idiopathic pulmonary artery hypertension received her father's right lower lobe and her mother's left lower lobe after pneumonectomy of both lungs in 2017. The patient has recovered well and is enjoying normal social activity. We think that LDLLT could be an alternative approach to deceased donor lung transplantation to overcome the shortage of lung donors.

  • https://doi.org/10.3346/jkms.2018.33.e282 인용 KSCI

Two Cases of Microscopic Polyangiitis with Honeycomb Lung (봉소상 폐(Honeycomb Lung) 소견을 보인 현미경적 다발성 혈관염 2예)

  • Hahn, Hye-Sook;Hwang, Jun-Kyu;Jung, Hyuk-Sang;Song, Suk-Ho;Joo, Kwon-Wook;Park, Gye-Young;Lee, Jong-Ho;Oh, Young-Ha;Lee, Hyoun-Joo
    • Tuberculosis and Respiratory Diseases
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    • v.52 no.5
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    • pp.550-556
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    • 2002

  • Microscopic polyangiitis is a systemic small-vessel vasculitis that is associated primarily with necrotizing glomerulonephritis and pulmonary capillaritis. A recurrent and diffuse alveolar hemorrhage due to pulmonary capillaritis is the main clinical manifestation of lung involvement. Recently, and interstitial lung disease that mimics idiopathic pulmonary fibrosis was reported to be rarely associated with microscopic polyangiitis. Here we report two patients with microscopic polyangiitis who showed a honeycomb lung at the time of the initial diagnosis with a brief review of relevant literature.

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