• Journal of Chest Surgery
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• v.28 no.9
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• pp.872-875
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• 1995

Dumbbell neurogenic tumor is a rare disease, arising about 10 % of mediastinal neurogenic tumor. We report a 31 year old man who was suffered from paresthesia and weakness of lower extremities for about 8 months. Chest x-rays revealed a dumbbell shaped mass shadow in left lower posterior mediastinum. MRI demonstrated a well defined dumbbell shaped mass in the mediastinum of T7 level, including spinal cord compression by the extended tumor into the spinal canal and enlarged intervertebral foramen. The patient underwent one-stage combined resection of the tumor through the thoracotomy and laminectomy, simultaneously. The tumor was confirmed as neurilemmoma. The postoperative course was smooth and uneventful.

• Journal of Chest Surgery
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• v.49 no.3
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• pp.218-220
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• 2016

We report a case of inadvertent hoarseness after surgery for primary pulmonary amyloidosis. A 55-year-old male was transferred to our facility due to a lung mass. Chest computed tomography revealed a solitary pulmonary nodule. Positron emission tomography-computed tomography showed fluorodeoxyglucose uptake in the main mass and in the mediastinal lymph nodes. To confirm the pathology of the mass, wedge resection and thorough lymph node dissection were performed via video-assisted thoracic surgery (VATS). No complications except for hoarseness were observed; hoarseness developed soon after surgery and lasted for 3 months. The main mass was diagnosed as amyloidosis, but this was not found in the lymph nodes. In conclusion, VATS wedge resection for peripheral amyloidosis is a feasible and safe procedure. However, mediastinal lymph node dissection is not recommended unless there is evidence of a clear benefit.

• Journal of Chest Surgery
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• v.23 no.1
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• pp.137-140
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• 1990

This report is an review of 40 cases of mediastinal tumors which were treated surgically in the Department of Thoracic and Cardiovascular Surgery, Chonnam University Hospital from January, 1985 to September, 1989. In this series, male to female sex distribution was 1.35:1 with the male predominant. The main clinical manifestations were chest pain and dyspnea, and there was no definitive symptom in 5 cases [12.5 %]. The most common mediastinal tumor was thymoma, 11 cases [27.5 %], and next common mass was germ cell tumor, 9 cases [22.5 %]. The half of these were malignant. In operating, all of the benign masses were removed.

• Journal of Chest Surgery
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• v.28 no.2
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• pp.209-212
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• 1995

Cystic hygroma is a cystic tumor developed by lymphatic stasis due to congenital blockage of regional lymphatic drainage. It ususally occurs at neck and axilla. However, in some cases of cervical cystic hygroma, cervical portions of the cysts may extend into the mediastinum. We experienced a case of huge cervico-mediastinal cystic tumor in 11 month old girl presenting a large fluctuating neck mass and severe respiratory distress. Surgical resection was done through combined approach of cervical incision and median sternotomy. Pathological diagnosis was confirmed to cervico-mediastinal cystic hygroma.

• Journal of Chest Surgery
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• v.27 no.6
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• pp.497-501
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• 1994

We have experienced a case of primary thymic carcinoma. A 39 year old female patient admitted with incidentally detected mediastinal mass on chest film.The tumor showed invasion to surrounding tissues and the mediastinal lymphadenopathies were also noted. Invasion to contiguous mediastinal structures made complete surgical extirplation impossible and the biposy findings revealed primary thymic carcinoma. Primary thymic carcinoma is a rare neoplasm originating from the thymic epithelial cells. Clinical behavior of the thymic carcinoma is much different from it`s benign counterpart and several pathologic variants were reported.

• Tuberculosis and Respiratory Diseases
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• v.70 no.2
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• pp.165-169
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• 2011

Pheochromocytomas are neuroendocrine tumors of chromaffin cell that originate in the paraganglia of the adrenal medulla. Approximately 10% of pheochromocytomas are found in the extra-adrenal paraganglia and are called paragangliomas. However, cases of middle mediastinal paragangliomas are very rare. In this case, the patient presented with a voice change and a headache. A middle mediastinal soft tissue mass with marked enhancement was detected on computed tomography of the chest. The 24-hour urine catecholamine level was markedly elevated. The middle mediastinal mass was biopsied via mediastinoscopy and the resulting immunohistochemical staining was compatible with a diagnosis of middle mediastinal paraganglioma. The mass was resected surgically and the symptoms were relieved.

• Journal of Chest Surgery
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• v.28 no.12
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• pp.1155-1159
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• 1995

Differentiated thyroid carcinoma is a slow growing tumor with relative good prognosis. But locally advanced thyroid cancer with T4 or N1b is difficult to manage. Between June 1988 and April 1995, we resected 8 advanced thyroid cancers trans-sternally. All patients had direct mediastinal extension [T4 or mediastinal lymph node metastasis [N1b with airway obstruction or dysphagia. We operated all the patients by partial or total sternotomy for mediastinal dissection along with thyroidectomy and radical neck dissection. There were some acceptable morbidities but no operative mortality. Postoperative radioactive iodine therapy was followed without side effects. Follow-up survival period was between 11 months to 81 months with 2 late mortalities [17 month, 30 month . Although definite benefit for routine mediastinal dissection in thyroid cancer has not been established, in locally advanced cases impending airway obstruction or dysphagia who have questionable effect by radioactive iodine therapy alone, aggressive mediastinal mass dissection including lymph node metastasis has the significant role to prevent the patients from suffocation & dysphagia, and to enhance the effect of followed radioactive iodine tharapy.

• Journal of Chest Surgery
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• v.19 no.2
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• pp.347-351
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• 1986

Soft-tissue chondroma was very rare in incidence and thought to be benign. Recently, we operated upon a 13 year-old female with a chondroma of the middle mediastinum, which was incidentally detected in chest X-ray as mediastinal mass, measured about 10x8x7 cm in size and completely resected via thoracotomy.

• Journal of Chest Surgery
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• v.29 no.11
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• pp.1281-1283
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• 1996

We describe the case of a 58-year-old woman who has coexisting intrapulmonary and mediastinal leiomyomas. Initially, she was seen with a single mass in the right lower hilar area in a simple chest roentgenogram. But computed tomography demonstrated another mass in the right posterior mediastinum. Microscopic examination and immunohistochemical staining of the resected specimens showed the characteristics of the leiomyoma.

• Clinical and Experimental Pediatrics
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• v.58 no.3
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• pp.108-111
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• 2015

DiGeorge syndrome is an immunodeficient disease associated with abnormal development of 3rd and 4th pharyngeal pouches. As a hemizygous deletion of chromosome 22q11.2 occurs, various clinical phenotypes are shown with a broad spectrum. Conotruncal cardiac anomalies, hypoplastic thymus, and hypocalcemia are the classic triad of DiGeorge syndrome. As this syndrome is characterized by hypoplastic or aplastic thymus, there are missing thymic shadow on their plain chest x-ray. Immunodeficient patients are traditionally known to be at an increased risk for malignancy, especially lymphoma. We experienced a 7-year-old DiGeorge syndrome patient with mediastinal mass shadow on her plain chest x-ray. She visited Severance Children's Hospital hospital with recurrent pneumonia, and throughout her repeated chest x-ray, there was a mass like shadow on anterior mediastinal area. We did full evaluation including chest computed tomography, chest ultrasonography, and chest magnetic resonance imaging. To rule out malignancy, video assisted thoracoscopic surgery was done. Final diagnosis of the mass which was thought to be malignancy, was lymphoproliferative lesion.