• Title/Summary/Keyword: Median diffusion

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Why Is a b-value Range of 1500-2000 s/mm2 Optimal for Evaluating Prostatic Index Lesions on Synthetic Diffusion-Weighted Imaging?

  • So Yeon Cha;EunJu Kim;Sung Yoon Park
    • Korean Journal of Radiology
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    • v.22 no.6
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    • pp.922-930
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    • 2021
  • Objective: It is uncertain why a b-value range of 1500-2000 s/mm2 is optimal. This study was aimed at qualitatively and quantitatively analyzing the optimal b-value range of synthetic diffusion-weighted imaging (sDWI) for evaluating prostatic index lesions. Materials and Methods: This retrospective study included 92 patients who underwent DWI and targeted biopsy for magnetic resonance imaging (MRI)-suggested index lesions. We generated sDWI at a b-value range of 1000-3000 s/mm2 using dedicated software and true DWI data at b-values of 0, 100, and 1000 s/mm2. We hypothesized that lesion conspicuity would be best when the background (i.e., MRI-suggested benign prostatic [bP] and periprostatic [pP] regions) signal intensity (SI) is suppressed and becomes homogeneous. To prove this hypothesis, we performed both qualitative and quantitative analyses. For qualitative analysis, two independent readers analyzed the b-value showing the best visual conspicuity of an MRI-suggested index lesion. For quantitative analysis, the readers assessed the b-value showing the same bP and pP region SI. The 95% confidence interval (CI) or interquartile range of qualitatively and quantitatively selected optimal b-values was assessed, and the mean difference between qualitatively and quantitatively selected b-values was investigated. Results: The 95% CIs of optimal b-values from qualitative and quantitative analyses were 1761-1805 s/mm2 and 1640-1771 s/mm2 (median, 1790 s/mm2 vs. 1705 s/mm2; p = 0.003) for reader 1, and 1835-1895 s/mm2 and 1705-1841 s/mm2 (median, 1872 s/mm2 vs. 1763 s/mm2; p = 0.022) for reader 2, respectively. Interquartile ranges of qualitatively and quantitatively selected optimal b-values were 1735-1873 s/mm2 and 1573-1867 s/mm2 for reader 1, and 1775-1945 s/mm2 and 1591-1955 s/mm2 for reader 2, respectively. Bland-Altman plots consistently demonstrated a mean difference of less than 100 s/mm2 between qualitatively and quantitatively selected optimal b-values. Conclusion: b-value range showing a homogeneous background signal may be optimal for evaluating prostatic index lesions on sDWI. Our qualitative and quantitative data consistently recommend b-values of 1500-2000 s/mm2.

Background Breast Parenchymal Signal During Menstrual Cycle on Diffusion-Weighted MRI: A Prospective Study in Healthy Premenopausal Women

  • Yeon Soo Kim;Bo La Yun;A Jung Chu;Su Hyun Lee;Hee Jung Shin;Sun Mi Kim;Mijung Jang;Sung Ui Shin;Woo Kyung Moon
    • Korean Journal of Radiology
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    • v.25 no.6
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    • pp.511-517
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    • 2024
  • Objective: To prospectively investigate the influence of the menstrual cycle on the background parenchymal signal (BPS) and apparent diffusion coefficient (ADC) of the breast on diffusion-weighted MRI (DW-MRI) in healthy premenopausal women. Materials and Methods: Seven healthy premenopausal women (median age, 37 years; range, 33-49 years) with regular menstrual cycles participated in this study. DW-MRI was performed during each of the four phases of the menstrual cycle (four examinations in total). Three radiologists independently assessed the BPS visual grade on images with b-values of 800 sec/mm2 (b800), 1200 sec/mm2 (b1200), and a synthetic 1500 sec/mm2 (sb1500). Additionally, one radiologist conducted a quantitative analysis to measure the BPS volume (%) and ADC values of the BPS (ADCBPS) and fibroglandular tissue (ADCFGT). Changes in the visual grade, BPS volume (%), ADCBPS, and ADCFGT during the menstrual cycle were descriptively analyzed. Results: The visual grade of BPS in seven women varied from mild to marked on b800 and from minimal to moderate on b1200 and sb1500. As the b-value increased, the visual grade of BPS decreased. On b800 and sb1500, two of the seven volunteers showed the highest visual grade in the early follicular phase (EFP). On b1200, three of the seven volunteers showed the highest visual grades in EFP. The BPS volume (%) on b800 and b1200 showed the highest value in three of the six volunteers with dense breasts in EFP. Three of the seven volunteers showed the lowest ADCBPS in the EFP. Four of the seven volunteers showed the highest ADCBPS in the early luteal phase (ELP) and the lowest ADCFGT in the late follicular phase (LFP). Conclusion: Most volunteers did not exhibit specific BPS patterns during their menstrual cycles. However, the highest BPS and lowest ADCBPS were more frequently observed in EFP than in the other menstrual cycle phases, whereas the highest ADCBPS was more common in ELP. The lowest ADCFGT was more frequent in LFP.

A Case of Acute Cerebral Motor Cortical Infarction Coincidentally Occurred in Segmental Zoster Paresis (분절성 대상포진마비와 동시에 발병한 급성 뇌운동피질경색 1예)

  • Do, Young Rok;Lee, Dong Kuck
    • Annals of Clinical Neurophysiology
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    • v.7 no.1
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    • pp.31-33
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    • 2005
  • Segmental zoster paresis (SZP) is a clinically rare complication of herpes zoster. But it has not been reported that acute cerebral motor cortical infarction coincidentally occurred in SZP. A 86-year-old woman was admitted due to pain, tingling sensation, and weakness of left arm. She had an acute onset of pain and tingling sensation in left arm at first day, shoulder weakness at second day, and multifocal vesicles at fourth day. Deep tendon reflexes of left arm were decreased than right. Electromyography showed an axonal polyneuropathy at superior trunk level of left brachial plexus. Median and ulnar sensory evoked potential tests were normal. Brain MRI showed a high signal in right primary motor cortex on diffusion weighted image. We report a case of acute cerebral motor cortical infarction coincidentally occurred in SZP.

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Aerosol Losses in a 100L $Tedlar^{(R)}$ Bag

  • Oh, Sewon
    • Journal of Korean Society for Atmospheric Environment
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    • v.20 no.E2
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    • pp.61-68
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    • 2004
  • Aerosol losses in a 100L Tedlar$^{(R)}$ bag were investigated for the aerosols with number median diameter of 0.05 ${\mu}{\textrm}{m}$ and number concentration of 6.4 ${\times}$ 10$^4$ cm$^{-3}$ . Over a 1 hr period, loss of particles in the bag is apparent, and the volume decrease with time is significant. The number concentration, surface area, and volume concentration of the aerosols decreased to 34, 50, and 52% of the initial value in 30 min, respectively. This indicates that deposition to the walls was the main loss process for aerosols in the Tedlar$^{(R)}$ bag. Theoretical calculations showed that coagulations and deposition by diffusion and gravitational sedimentation would not change aerosol characteristics significantly, and the electrical force was the dominant loss process for particles in the Tedlar$^{(R)}$ bag over a 1 hr period.eriod.

A Study of Wind Characteristics around Nuclear Power Plants Based on the Joint Distribution of the Wind Direction and Wind Speed

  • Yunjong Lee
    • Journal of Radiation Industry
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    • v.17 no.3
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    • pp.299-307
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    • 2023
  • Given that toxic substances are diffused by the various movements of the atmosphere, it is very important to evaluate the risks associated with this phenomenon. When analyzing the behavioral characteristics of these atmospheric diffusion models, the main input data are the wind speed and wind direction among the meteorological data. In particular, it is known that a certain wind direction occurs in summer and winter in Korea under the influence of westerlies and monsoons. In this study, synoptic meteorological observation data provided by the Korea Meteorological Administration were analyzed from January 1, 2012 to the end of August of 2022 to understand the regional wind characteristics of nuclear power plants and surrounding areas. The selected target areas consisted of 16 weather stations around the Hanbit, Kori, Wolsong, Hanul, and Saeul nuclear power plants that are currently in operation. The analysis was based on the temperature, wind direction, and wind speed data at those locations. Average, maximum, minimum, median, and mode values were analyzed using long-term annual temperature, wind speed, and wind direction data. Correlation coefficient values were also analyzed to determine the linear relationships among the temperature, wind direction, and wind speed. Among the 16 districts, Uljin had the highest wind speed. The median wind speed values for each region were lower than the average wind speed values. For regions where the average wind speed exceeds the median wind speed, Yeongju, Gochang, Gyeongju, Yeonggwang, and Gimhae were calculated as 0.69 m s-1, 0.54m s-1, 0.45m s-1, 0.4m s-1, and 0.36m s-1, respectively. The average temperature in the 16 regions was 13.52 degrees Celsius; the median temperature was 14.31 degrees and the mode temperature was 20.69 degrees. The average regional temperature standard deviation was calculated and found to be 9.83 degrees. The maximum summer temperatures were 39.7, 39.5, and 39.3 in Yeongdeok, Pohang, and Yeongcheon, respectively. The wind directions and speeds in the 16 regions were plotted as a wind rose graph, and the characteristics of the wind direction and speed of each region were investigated. It was found that there is a dominant wind direction correlated with the topographical characteristics in each region. However, the linear relationship between the wind speed and direction by region varied from 0.53 to 0.07. Through this study, by evaluating meteorological observation data on a long-term synoptic scale of ten years, regional characteristics were found.

The Location of Broadcasting Stations and Spatial Organization of Cable Television in Korea (케이블 TV 방송국의 입지와 공간조직)

  • 한주성
    • Journal of the Korean Geographical Society
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    • v.32 no.2
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    • pp.141-153
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    • 1997
  • In Korea, cable television(CATV) broadcasting has begun in March, 1995. This Paper aims at examining the location of CATV broadcasting station, and demand density(numbers of viewer houshold) of broadcasting area, and at clarifing the factors affecting subscription. The results are as follows: The number of CATV stations is 54 in 1996, and these CATV stations are mainly located in larger cities. The correlation between the number of established or planned CATV station and the number of household is very high. In sphered broadcasting area Permitted in 1997, the location of CATV station is about 73,000 household and 230,000 persons in the minimum values of household and population, and diameter of sphered broadcasting area is 40.6 km in mean. The factors affecting subscription rates of CATV are median age and supply rates of apartment of each dong in Chongju city and each myun in Chongwon county. The correlation between subscription rates of CATV and supply rates of apartment appears higher than correlation between subscription rates and median age other factors based on residual analysis of regression equation are established period of transmission network of CATV and acceptance attitude of dwellers.

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A Study on the Dyadic Sorting method for the Regularization in DT-MRI (Dyadic Sorting 방법을 이용한 DT-MRI Regularization에 관한 연구)

  • Kim, Tae-Hwan;Woo, Jong-Hyung;Lee, Hoon;Kim, Dong-Youn
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.47 no.4
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    • pp.30-39
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    • 2010
  • Since Diffusion tensor from Diffusion Tensor Magnetic Resonance Imaging(DT-MRI) is so sensitive to noise, the principle eigenvector(PEV) calculated from Diffusion tensor could be erroneous. Tractography obtained from PEV could be deviated from the real fiber tract. Therefore regularization process is needed to eliminate noise. In this paper, to reduce noise in DT-MRI measurements, the Dyadic Sorting(DS) method as regularization of the eigenvalue and the eigenvector is applied in the tractography. To resort the eigenvalues and the eignevectors, the DS method uses the intervoxel overlap function which can measure the overlap between eigenvalue-eigenvector pairs in the $3\times3$ pixel. In this paper, we applied the DS method to the three-dimensional volume. We discuss the error analysis and numerical study to the synthetic and the experimental data. As a result, we have shown that the DS method is more efficient than the median filtering methods as much as 79.97%~83.64%, 85.62%~87.76% in AAE, AFA respectively for the corticospinal tract of the experimental data.

Preoperative Prediction of Ductal Carcinoma in situ Underestimation of the Breast using Dynamic Contrast Enhanced and Diffusion-weighted Imaging (역동적 유방 자기공명 영상 및 확산 강조영상을 이용한 관상피내암종 저평가 수술전 예측)

  • Park, Mina;Kim, Eun-Kyung;Kim, Min Jung;Moon, Hee Jung
    • Investigative Magnetic Resonance Imaging
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    • v.17 no.2
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    • pp.101-109
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    • 2013
  • Objective: To investigate roles of dynamic contrast enhanced magnetic resonance (DCE MR) and diffusion-weighted (DW) imaging in preoperative prediction of underestimation of ductal carcinoma in situ (DCIS) ${\geq}2cm$ on US guided core needle biopsy. Materials and Methods: Twenty two patients with DCIS on US-guided 14 gauge core needle biopsy were included. Patients were divided into a group with and without DCIS underestimation based on histopathology. MR images including DCE and DW imaging were obtained with a 3.0-T MR. The lesion type (mass or non-mass), enhancement pattern, peak enhancement, and apparent diffusion coefficient (ADC) values of proven malignant masses were generated using software of CADstream and compared between two groups using Fisher's exact test and Mann Whitney test. Results: Eight patients were in the group with underestimation and 14 patients were in the group without underestimation. The lesion type and enhancement pattern were not different between two groups (P values = 1.000 and 0.613, respectively). The median peak enhancement of lesions with underestimation was 159.5%, higher than 133.5% of those without underestimation, but not significant (P value = 0.413). The median ADC value of lesions with underestimation was $1.26{\times}10^{-3}mm^2/sec$, substantially lower than $1.35{\times}10^{-3}mm^2/sec$ of those without underestimation (P value = 0.094). Conclusion: ADC values had the potential to preoperatively predict DCIS underestimation on US-guided core needle biopsy, although a large prospective series study should be conducted to confirm these results.

A Study on No-line Filter for Image Denoising (영상 잡음제거를 위한 비선형 필터에 관한 연구)

  • Long, Xu;Kim, Nam-Ho
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2013.05a
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    • pp.411-413
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    • 2013
  • Image signal processing is applied in different areas due to diffusion of smart phone, computer, multimedia etc. However, image most is damaged by impulse noise, and the need of denoising technology for improvement of image quality is coming to the fore. The existing methods for denoising such as mean filter and median filter, but they represent poor denoising. Therefore, the removes impulse noise, this paper proposed the modified mean filter algorithm using standard deviation, and as a simulation result, the proposed method showed excellent denoising capabilities to the existing methods.

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Surgical Outcomes of Thalamic Tumors in Children: The Importance of Diffusion Tensor Imaging, Neuro-Navigation and Intraoperative Neurophysiological Monitoring

  • Kim, Jun-Hoe;Phi, Ji Hoon;Lee, Ji Yeoun;Kim, Kyung Hyun;Park, Sung-Hye;Choi, Young Hun;Cho, Byung-Kyu;Kim, Seung-Ki
    • Brain Tumor Research and Treatment
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    • v.6 no.2
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    • pp.60-67
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    • 2018
  • Background Recently, modern technology such as diffusion tensor imaging (DTI), neuro-navigation and intraoperative neurophysiological monitoring (IOM) have been actively adopted for the treatment of thalamic tumors. We evaluated surgical outcomes and efficacy of the aforementioned technologies for the treatment of pediatric thalamic tumors. Methods We retrospectively reviewed clinical data from 37 children with thalamic tumors between 2004 and 2017. There were 44 operations (27 tumor resections, 17 biopsies). DTI was employed in 17 cases, neuro-navigation in 23 cases and IOM in 14 cases. All diagnoses were revised according to the 2016 World Health Organization Classification of Tumors of the Central Nervous System. Progression-free survival (PFS) and overall survival (OS) rates were calculated, and relevant prognostic factors were analyzed. The median follow-up duration was 19 months. Results Fifteen cases were gross total resections (GTR), 6 subtotal resections (STR), and 6 partial resections (PR). Neurological status did not worsen after 22 tumor resections. There were statistically significant differences in terms of the extent of resection between the groups with DTI, neuro-navigation and IOM (n=12, GTR or STR=12) and the group without at least one of the three techniques (n= 15, GTR or STR=9, p=0.020). The mean PFS was $87.2{\pm}38.0$ months, and the mean OS $90.7{\pm}36.1$ months. The 5-year PFS was 37%, and the 5-year OS 47%. The histological grade ($p{\leq}0.001$) and adjuvant therapy (done vs. not done, p=0.016) were significantly related to longer PFS. The histological grade (p=0.002) and the extent of removal (GTR/STR vs. PR/biopsy, p=0.047) were significantly related to longer OS. Conclusion Maximal surgical resection was achieved with acceptable morbidity in children with thalamic tumors by employing DTI, neuro-navigation and IOM. Maximal tumor resection was a relevant clinical factor affecting OS; therefore, it should be considered the initial therapeutic option for pediatric thalamic tumors.