• 한국통신학회논문지
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• 제32권5C호
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• pp.542-549
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• 2007

편미분 방정식을 도입하여 새로운 영상처리 기술을 개발하려는 연구가 활발히 진행 중이며, 특히 확산 방정식을 풀어 잡음 제거, 영상 복원, 에지 검출 및 영상 분할 등에 응용할 수 있는 이미지 확산 알고리즘에 관심이 높다. 본 논문에서는 기존의 비등방성 확산 방식이 결국은 커널 크기가 작은 적응 필터링 방식과 동일한 효과를 낸다는 것을 보이고, 확산 과정에서 선형 필터의 단점을 보완할 수 있도록 가중 미디언(WM, Weighted Median) 필터를 적용한 새로운 확산 기법을 제안하였다. 제안된 WM 필터가 비등방성 커널을 갖도록 필터계수에 대응하는 가중치들을 이미지의 국부적인 변화량에 따라 적응적으로 가변할 수 있는 기법을 제안하였다. 뿐만 아니라 반복 과정에서의 확산 속도를 증가할 수 있도록 커널의 크기를 증가시키기 위한 방안도 제시하였다. 실제 영상을 사용한 실험을 통하여 제안된 방식이 기존의 방식에 비해 잡음 제거 (특히 임펄스성 잡음) 특성이나 에지 보존 특성이 더 우수하다는 것을 보였다. 또한 기존의 방식에 비해 확장된 크기를 갖는 커널을 이용함으로써 확산 속도를 높일 수 있다는 것을 보였다.

• 대한원격탐사학회지
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• 제31권1호
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• pp.21-28
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• 2015

The essential idea of de-noising is referring to neighboring pixels of a center pixel to be updated. Conventional adaptive de-noising filters use local statistics, i.e., mean and variance, of neighboring pixels including the center pixel. The drawback of adaptive de-noising filters is that their performance becomes low when edges are contained in neighboring pixels, while anisotropic diffusion de-noising filters remove adaptively noises and preserve edges considering intensity difference between neighboring pixel and the center pixel. The anisotropic diffusion de-noising filters, however, use only intensity difference between neighboring pixels and the center pixel, i.e., local statistics of neighboring pixels and the center pixel are not considered. We propose a new connectivity function of two adjacent pixels using statistics of neighboring pixels and apply connectivity function to diffusion coefficient. Experimental results using an aerial image corrupted by uniform and Gaussian noises showed that the proposed algorithm removed more efficiently noises than conventional diffusion filter and median filter.

• 콘크리트학회논문집
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• 제15권2호
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• pp.345-351
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• 2003

The transport characteristics of deleterious ions such as chlorides depend on the pore structures of concrete and are the major factors in the durability of concrete structures in subjected to chloride attack such as in marine environments. In this paper, the effect of the pore structure on compressive strength and chloride diffusivity of concrete was investigated. Six types of concretes were tested. The pore volume of concrete containing mineral admixtures increased in the range of 3∼30nm due to micro filling effect of hydrates of the mineral admixtures. There was a good correlation between the median pore diameter, the pore volume above 50nm and compressive strength of concrete, but there was not a significant correlation between the total pore volume and compressive strength. The relationship between compressive strength and chloride diffusivity were not well correlated, however, pore volume above 50nm were closely related to the chloride diffusion coefficient.

• 대한의용생체공학회:의공학회지
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• 제28권6호
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• pp.817-824
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• 2007

Tractography using Diffusion Tensor Magnetic Resonance Imaging (DT-MRI) is a method to determine the architecture of axonal fibers in the central nervous system by computing the direction of the principal eigenvector in the white matter of the brain. However, the fiber tracking methods suffer from the noise included in the diffusion tensor images that affects the determination of the principal eigenvector. As the fiber tracking progresses, the accumulated error creates a large deviation between the calculated fiber and the real fiber. This problem of the DT-MRI tractography is known mathematically as the ill-posed problem which means that tractography is very sensitive to perturbations by noise. To reduce the noise in DT-MRI measurements, a tensor-valued median filter which is reported to be denoising and structure-preserving in fiber tracking, is applied in the tractography. In this paper, we proposed the modified gradient descent method which converges fast and accurately to the optimal tensor-valued median filter by changing the step size. In addition, the performance of the modified gradient descent method is compared with others. We used the synthetic image which consists of 45 degree principal eigenvectors and the corticospinal tract. For the synthetic image, the proposed method achieved 4.66%, 16.66% and 15.08% less error than the conventional gradient descent method for error measures AE, AAE, AFA respectively. For the corticospinal tract, at iteration number ten the proposed method achieved 3.78%, 25.71 % and 11.54% less error than the conventional gradient descent method for error measures AE, AAE, AFA respectively.

• Korean Journal of Radiology
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• 제23권1호
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• pp.60-67
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• 2022

Objective: To categorize multiparametric MRI features of Bacillus Calmette-Guérin (BCG)-related granulomatous prostatitis (GP) and discover potential manifestations for its differential diagnosis from prostate cancer. Materials and Methods: The cases of BCG-related GP in 24 male (mean age ± standard deviation, 66.0 ± 9.4 years; range, 50-88 years) pathologically confirmed between January 2011 and April 2019 were retrospectively reviewed. All patients underwent intravesical BCG therapy followed by a MRI scan. Additional follow-up MRI scans, including diffusion-weighted imaging (DWI), were performed in 19 patients. The BCG-related GP cases were categorized into three: A, B, or C. The lesions with diffusion restriction and homogeneous enhancement were classified as type A. The lesions with diffusion restriction and a poorly enhancing component were classified as type B. A low signal intensity on high b-value DWI (b = 1000 s/mm²) was considered characteristic of type C. Two radiologists independently interpreted the MRI scans before making a consensus about the types. Results: The median lesion size was 22 mm with the interquartile range (IQR) of 18-26 mm as measured using the initial MRI scans. The lesion types were A, B, and C in 7, 15, and 2 patients, respectively. Cohen's kappa value for the inter-reader agreement for the interpretation of the lesion types was 0.837. On the last follow-up MRI scans of 19 patients, the size decreased (median, 5.8 mm; IQR, 3.4-8.5 mm), and the type changed from A or B to C in 11 patients. The lesions resolved in four patients. In five patients who underwent prostatectomy, caseous necrosis on histopathology matched with the non-enhancing components of type B lesions and the entire type C lesions. Conclusion: BCG-related GP demonstrated three imaging patterns on multiparametric MRI. Contrast-enhanced T1-weighted imaging and DWI may play a role in its differential diagnosis from prostate cancer.

• Investigative Magnetic Resonance Imaging
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• 제21권3호
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• pp.154-161
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• 2017

Purpose: To evaluate the diagnostic performance of diffusion-weighted steady-state free precession (DW-SSFP) in comparison to diffusion-weighted echo-planar imaging (DW-EPI) for differentiating the neoplastic and benign osteoporotic vertebral compression fractures. Materials and Methods: The subjects were 40 patients with recent vertebral compression fractures but no history of vertebroplasty, spine operation, or chemotherapy. They had received 3-Tesla (T) spine magnetic resonance imaging (MRI), including both DW-SSFP and DW-EPI sequences. The 40 patients included 20 with neoplastic vertebral fracture and 20 with benign osteoporotic vertebral fracture. In each fracture lesion, we obtained the signal intensity normalized by the signal intensity of normal bone marrow (SI norm) on DW-SSFP and the apparent diffusion coefficient (ADC) on DW-EPI. The correlation between the SI norm and the ADC in each lesion was analyzed using linear regression. The optimal cut-off values for the diagnosis of neoplastic fracture were determined in each sequence using Youden's J statistics and receiver operating characteristic curve analyses. Results: In the neoplastic fracture, the median SI norm on DW-SSFP was higher and the median ADC on DW-EPI was lower than the benign osteoporotic fracture (5.24 vs. 1.30, P = 0.032, and 0.86 vs. 1.48, P = 0.041, respectively). Inverse linear correlations were evident between SI norm and ADC in both neoplastic and benign osteoporotic fractures (r = -0.45 and -0.61, respectively). The optimal cut-off values for diagnosis of neoplastic fracture were SI norm of 3.0 in DW-SSFP with the sensitivity and specificity of 90.4% (95% confidence interval [CI]: 81.0-99.0) and 95.3% (95% CI: 90.0-100.0), respectively, and ADC of 1.3 in DW-EPI with the sensitivity and specificity of 90.5% (95% CI: 80.0-100.0) and 70.4% (95% CI: 60.0-80.0), respectively. Conclusion: In 3-T MRI, DW-SSFP has comparable sensitivity and specificity to DW-EPI in differentiating the neoplastic vertebral fracture from the benign osteoporotic vertebral fracture.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2002년도 하계학술대회 논문집
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• pp.40-42
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• 2002

Electromigration is atomic diffusion driven by a momentum transfer from conducting electrons. With every new generation of intergrated circuits, interconnect line widths have been reduced and current densities in the interconnect have become higher. This leads to an increase in the threat to interconnect reliability due to electromigration. In this paper, we simulated stress evolution with changing temperature, duty factor(ratio of on time and pulse time), frequency under pulsed DC condition. As a result, we predict MTF(median time to failure) and found that exponent n is affected by changing temperature, duty factor.

• 실내환경 및 냄새 학회지
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• 제17권4호
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• pp.362-371
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• 2018

Indoor Volatile organic compounds (VOCs) are classified as known or possible toxicants and odorants. This study characterized VOC levels in 11 homes in an area in the capital of Seoul by using two different methods of VOCs sampling, which are the active sampling using a thermal sorption tube and the passive sampling using a diffusion sampler. When using the active sampling method, the total target VOC concentration ranged from 41.7 to $420.7{\mu}g/m^3$ (mean $230.4{\mu}g/m^3$ ; median $221.8{\mu}g/m^3$) during winter and 21.3 to $1,431.9{\mu}g/m^3$ (mean $340.1{\mu}g/m^3$; median $175.4{\mu}g/m^3$) during summer. When using the passive method, 29.6 to $257.5{\mu}g/m^3$ (mean $81.8{\mu}g/m^3$; median $49.4{\mu}g/m^3$) during winter and 1.2 to $5,131.1{\mu}g/m^3$ (mean $1,758.8{\mu}g/m^3$; median $1,375.1{\mu}g/m^3$) during summer. Forty-nine VOCs were quantified and toluene showed the highest concentration regardless of the season and the sampling method studied. The distribution of VOCs was relatively varied by using the active method. However, it showed a low correlation with indoor environmental factors such as room temperature, humidity and ventilation time. The correlation between indoor environmental factors and VOCs were relatively high in the passive method. In particular, these characteristics were confirmed by principal component analysis.

• 한국산학기술학회논문지
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• 제19권7호
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• pp.36-41
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• 2018

미광증폭장비는 밤과 같이 어두운 환경에서 주로 가시광선 대역의 약한 빛을 증폭시켜 육안으로 관측할 수 있을 정도의 밝기로 만들어주는 장비이다. 이러한 방식은 어느 정도의 약한 빛이 존재하는 환경에서는 그 증폭 효과를 제대로 발휘하여 선명한 영상을 얻을 수 있지만, 달빛조차 존재하지 않는 극 저조도 환경에서는 기본적으로 증폭시킬 빛이 부족하여 출력 영상에 많은 노이즈로 인하여 화면의 선명도가 저하된다. 본 연구에서는 이러한 극 저조도 환경에서 발생하는 미광증폭 장비의 출력 노이즈를 다중 필터와 이방성 확산을 이용하여 화질을 개선하는 방법을 제안하였다. 실험을 위하여 극 저조도 조건에 맞는 환경을 구성한 상태에서 미광증폭장비의 출력 영상을 촬영한 후, 화질 개선을 위한 신호처리를 하였다. 신호처리를 위한 필터의 구성은 영상에 나타나는 주된 노이즈인 점 노이즈 제거와 가우시안 노이즈의 효과적인 제거를 위하여 메디안 필터, 위너 필터를 적용시킨 후 이방성 확산을 이용하였다. 실험 결과 화질이 개선됨을 육안으로 확인할 수 있었고, 정량 지표인 PSNR 및 SSIM으로 비교하여 측정한 방법에서도 모두 개선된 값을 보여주었다.

• Investigative Magnetic Resonance Imaging
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• 제20권2호
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• pp.81-87
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• 2016

Purpose: To analyze the feasibility of three-dimensional (3D) diffusion-weighted (DW) PSIF (reversed FISP [fast imaging with steady-state free precession]) sequence in order to evaluate peripheral nerves in the elbow. Materials and Methods: Ten normal, asymptomatic volunteers were enrolled (6 men, 4 women, mean age 27.9 years). The following sequences of magnetic resonance images (MRI) of the elbow were obtained using a 3.0-T machine: 3D DW PSIF, 3D T2 SPACE (sampling perfection with application optimized contrasts using different flip angle evolution) with SPAIR (spectral adiabatic inversion recovery) and 2D T2 TSE (turbo spin echo) with modified Dixon (m-Dixon) sequence. Two observers used a 5-point grading system to analyze the image quality of the ulnar, median, and radial nerves. The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of each nerve were measured. We compared 3D DW PSIF images with other sequences using the Wilcoxon-signed rank test and Friedman test. Inter-observer agreement was measured using intraclass correlation coefficient (ICC) analysis. Results: The mean 5-point scores of radial, median, and ulnar nerves in 3D DW PSIF (3.9/4.2/4.5, respectively) were higher than those in 3D T2 SPACE SPAIR (1.9/2.8/2.8) and 2D T2 TSE m-Dixon (1.7/2.8/2.9) sequences (P < 0.05). The mean SNR in 3D DW PSIF was lower than 3D T2 SPACE SPAIR, but there was no difference between 3D DW PSIF and 2D T2 TSE m-Dixon in all of the three nerves. The mean CNR in 3D DW PSIF was lower than 3D T2 SPACE SPAIR and 2D T2 TSE m-Dixon in the median and ulnar nerves, but no difference among the three sequences in the radial nerve. Conclusion: The three-dimensional DW PSIF sequence may be feasible to evaluate the peripheral nerves around the elbow in MR imaging. However, further optimization of the image quality (SNR, CNR) is required.