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Does Single Blind Anterior Glenohumeral Steroid Injection Performed by Short Experienced Clinicians Could Provide Clinical Efficacy in Patients with Frozen Shoulder?

  • Hong, Jin Ho;Ryu, Ho Young;Park, Yong Bok;Jeon, Sang Jun;Park, Won Ha;Yoo, Jae Chul
    • Clinics in Shoulder and Elbow
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    • v.17 no.3
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    • pp.102-106
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    • 2014
  • Background: The purpose of this study was to evaluate the effect of single blinded anterior intra-articular corticosteroid injection to the glenohumeral joint performed by short experienced clinicians in frozen state adhesive capsulitis patients. Methods: From March to June of 2013, among the patients who visited the shoulder outpatient clinic due to shoulder pain for 5-6 months and those patient diagnosed as frozen state adhesive capsulitis was selected. The diagnosis were based on base, first the global limitation of range of motion, defined as forward elevation <100, external rotation at side <10, internal rotation less than buttock, and abduction <70. Second, the patients had additional radiologic evaluations showing no major pathologies for such stiffness. Clinical outcome, were performed with pain visual analog scale (PVAS) and functional visual analog scale (FVAS), American Shoulder and Elbow Surgeons Shoulder score (ASES), preinjection and postinjection after 2-4 weeks. Finally 82-patients were enrolled. Mean age of the patients was 55.1 years and mean follow-up duration was 25.17 days. Results: The mean preinjection PVAS was 6.91 and postinjection was 3.11, there was 3.8 decreases from preinjection status (p < 0.001). The mean FVAS score showed 4.26 at preinjection and 6.63 afterwards (p < 0.001). The ASES score showed 27.89 increases after injection (p < 0.001). There were 64-patients (78.04%) who reported more than 3 points of decrease of PVAS, who could be judged as effective treatment. Conclusions: Single anterior glenohumeral steroid injection by short experienced clinicians to the patients with frozen state adhesive capsulitis has shown relatively high efficacy in clinical result evaluated by means of PVAS.

Anti-Platelet Drug Resistance in the Prediction of Thromboembolic Complications after Neurointervention

  • Ryu, Dal-Sung;Hong, Chang-Ki;Sim, Yoo-Sik;Kim, Chang-Hyun;Jung, Jin-Young;Joo, Jin-Yang
    • Journal of Korean Neurosurgical Society
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    • v.48 no.4
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    • pp.319-324
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    • 2010
  • Objective : The aim of this study was to analyze the correlation between thromboembolic complications and anti platelet drugs before and after neurointervention. Methods : Blood samples and radiographic data of patients who received a neurointervention (coil embolization, stent placement or both) were collected prospectively. Rapid platelet function assay-aspirin (RPFA-ASA) was used to calculate aspirin resistance in aspirin reaction units (ARU). For clopidogrel resistance, a P2Y12 assay was used to analyze the percentage of platelet inhibition. ARU > 550 and platelet inhibition < 40% were defined as aspirin and clopidogrel resistance, respectively. Results : Both aspirin and clopidogrel oral pills were administered in fifty-three patients before and after neurointerventional procedures. The mean resistance values of all patients were 484 ARU and < 39%. Ten (17.0%) of 53 patients showed resistance to aspirin with an average of 597 ARU, and 33 (62.3%) of 53 patients showed resistance to clopidogrel with an average of < 26%. Ten patients demonstrated resistance to both drugs, 5 of which suffered a thromboembolic complication after neurointervention (mean values : 640 ARU and platelet inhibition < 23%). Diabetic patients and patients with hypercholesterolemia displayed mean aspirin resistances of 513.7 and 501.8 ARU, and mean clopidogrel resistances of < 33.8% and < 40.7%, respectively. Conclusion : Identifying individuals with poor platelet inhibition using standard regimens is of great clinical importance and may help prevent cerebral ischemic events in the future. Neurointerventional research should focus on ideal doses, timing, choices, safety, and reliable measurements of anti platelet drug therapy, as well as confirming the clinical relevance of aggregometry in cerebrovascular patients.

A study of Gongjin-dan in patients with mild Dementia of Alzheimer type (공진단(供辰丹)이 알츠하이머형 치매 환자에게 미치는 영향)

  • Jang, Ha-Jeong;Sung, Woo-Yong;Lee, Seung-Hyun;Son, Ji-Hyung;Han, Seung-Hea;Jung, Hyo-Chang
    • Journal of Oriental Neuropsychiatry
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    • v.15 no.2
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    • pp.141-148
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    • 2004
  • Objective : This study is designed to assess the effects of Gongjin-dan on cognitive decline of the patients with mild Dementia of Alzheimer Type(DAT). Method : 33 patients with mild DAT were measured by using K-DRS, and after 100 days again. During 100 days the patients with mild DAT were treated with Gongjin-dan. The scores of K-DRS between before and after treatment were analyzed by paired t-Test. Result : 1. the mean age of patients was $70.3{\pm}4.1$ years (range 65 to 84 years) 2. the mean education of patients was $5.5{\pm}5.3$ years 3. the mean K-DRS score of the patients before treatment was $93.2{\pm}12.1$, and the mean K-DRS score of the patients after treatment was $114.7{\pm}14.5$. K-DRS scores after treatment was significantly different with the K-DRS scores before treatment.(t=9.907, r=.573, p<.00l) Conclusion : Treatment with Gongjin-dan for 100 days increased the cognitive ability in patients with mild DAT

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Study on Consumer Exposure to Sun Spray and Sun Cream in South Korea

  • Oh, Mihyun;Kim, Seoyoung;Han, Jieun;Park, Sodam;Kim, Go Un;An, Susun
    • Toxicological Research
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    • v.35 no.4
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    • pp.389-394
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    • 2019
  • When conducting risk assessments of cosmetic ingredients, it is important that reliable exposure information is obtained for cosmetic products. As cosmetics are becoming more diverse, continuous effort must be made to obtain exposure data that reflect their growth and usage trends. The usage pattern of cosmetics, such as the application area and amount used, may differ by product type and also by country. We conducted a survey to compare the amount of sun spray and sun cream used in a usage environment in South Korea. The study was conducted on Haeundae Beach, one of the most popular beaches in South Korea. A total of 1,255 beachgoers participated in this study; 604 and 651 participants used the sun spray and sun cream, respectively, while sunbathing and enjoying water activities on the beach for one day. Exposure was analyzed following a probabilistic method. On comparing all subjects, it was found that the group that used sun spray (mean: 44.52 g/day) used significantly more product (p = 0.000) than those who used sun cream (mean: 20.51 g/day). By analyzing the daily exposure of sun spray and sun cream per unit body weight according to age and gender, the exposure amount of sun spray and sun cream was found to be highest among 2~9 year-old girls (mean for sun spray: 2.51 g/kg/day, p95: 5.50 g/kg/day, mean for sun cream: 0.79 g/kg/day, p95: 1.79 g/kg/day). The amount of sun spray used is approximately twice that of sun cream. Among both the sun spray and sun cream groups, the exposure amount per unit body weight was highest in girls younger than 10. These factors should be considered when conducting risk assessments of sun spray and sun cream.

Comparison of mean platelet volume levels in coronary artery ectasia and healthy people: systematic review and meta-analysis

  • Moghadam, Reza Heidary;Shahmohammadi, Afshar;Asgari, Nader;Azizi, Koorosh;Mansour, Sahar Mehr;Roozbahani, Mohammad
    • BLOOD RESEARCH
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    • v.53 no.4
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    • pp.269-275
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    • 2018
  • Coronary artery ectasia (CAE) is defined as the dilation of a segment of a coronary vessel to at least 1.5 times the diameter of its normal adjacent segment. Mean platelet volume (MPV) plays a role in acute coronary syndromes, with high MPV correlating to poor prognosis for acute thrombotic events and CAE. Several studies investigated the relationship between MPV and CAE, resulting in conflicting results. These results led us to systematically review all studies investigating the relationship between MPV and ectatic heart diseases by performing a meta-analysis study in order to report a unified result. This meta-analysis study investigated all case-control articles examining the relationship between MPV and CAE. All studies in the following databases published until January 31, 2018, were investigated: Science Direct, Scopus, PubMed, Google Scholar, and Web of Science. Following a quality control evaluation, 14 articles, all of which were published following studies performed in Turkey from 2007 to 2016, met the criteria for study inclusion. After pooling the results from all of the articles, a total standardized mean difference (SMD) value of 0.584 (95% CI, 0.219, 0.95) was obtained using the D+L pooled SMD, indicating a significant difference (P=0.002) between the two groups, with higher MPV values in ectatic patients when comparing to healthy individuals. Therefore, increased MPV levels were significantly related to CAE, suggesting that platelets, with their inflammatory and thrombotic activities, play a role in this disease. Therefore, anti-platelet and anti-inflammatory therapies may be effective in treating CAE.

Effects of commercial soils on germination, early growth, and chlorophyll content of Aspilia africana, a medicinal plant

  • Okello, Denis;Komakech, Richard;Kim, Yong-Goo;Rahmat, Endang;Chung, Yuseong;Omujal, Francis;Kang, Youngmin
    • Journal of Plant Biotechnology
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    • v.48 no.2
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    • pp.115-122
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    • 2021
  • Aspilia africana (Pers) C.D.Adams, a plant used for centuries in many African countries to treat diseases such as osteoporosis, malaria, tuberculosis, and diabetes, is of great pharmaceutical interest, yet there is limited scientific literature on its germination and growth. This research paper describes the effects of different commercial soils on the germination, growth, and chlorophyll content of A. africana. The germination parameters assessed included final germination percentage (FGP), mean germination time (MGT), and germination index (GI). Shoot length, leaf number, and fresh and dry weights were some of the parameters used to assess A. africana growth. The FGP was low and did not vary significantly; the MGT was 7 ~ 10 days; and the GI was significantly higher in PPS soil at 4.61 ± 0.332 days. Aspilia africana plants in HS:PPS soil showed the best overall growth, producing the highest mean leaf number (18.00 ± 1.129), longest mean shoot length (202.43 ± 13.451 mm), and highest mean fresh and dry weights (7.08 ± 1.061 g and 0.629 ± 0.112 g, respectively). The highest chlorophyll content in leaves of A. africana under HS:PPS conditions suggested a higher photosynthetic potential of plants in this soil. The best growth performance of A. africana in the HS:PPS soil could be attributed to a higher amount of certain mineral nutrients such as nitrogen, potassium, and phosphorus in the HS:PPS soil compared to the other soil categories. It is unclear why the FGP of A. africana was low and we recommend an exclusive study to investigate this further.

Effect on the Center of Pressure of Vision, Floor Condition, and the Height of Center of Mass During Quiet Standing

  • Kim, Seung-su;Lim, Kitaek;Choi, Woochol Joseph
    • Physical Therapy Korea
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    • v.28 no.2
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    • pp.154-160
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    • 2021
  • Background: Theoretically, balance is affected by the height of center of mass (COM) during quiet standing. However, no one examined this in humans with variables derived from the center of pressure (COP). Objects: We have conducted balance experiment to measure COP data during quiet standing, in order to examine how the COP measures were affected by the height of COM, vision, floor conditions, and gender. Methods: Twenty individuals stood still with feet together and arms at sides for 30 seconds on a force plate. Trials were acquired with three COM heights: 1% increased or decreased, and not changed, with two vision conditions: eyes closed (EC) and eyes open (EO), and with two floor conditions: unstable (foam pad) and stable (force plate) floor. Outcome variables included the mean distance, root mean square distance, total excursion, mean velocity, and 95% confidence circle area. Results: All outcome variables were associated with the COM height (p < 0.0005), vision (p < 0.0005), and floor condition (p < 0.003). The mean velocity and 95% confidence circle area were 5.7% and 21.8% greater, respectively, in raised COM than in lowered COM (24.6 versus 23.2 mm/s; 1,013.4 versus 832.3 mm2). However, there were no interactions between the COM height and vision condition (p > 0.096), and between the COM height and floor condition (p > 0.183) for all outcome variables. Furthermore, there was no gender difference in all outcome variables (p > 0.186). Conclusion: Balance was affected by the change of COM height induced by a weight belt in human. However, the effect was not affected by vision or floor condition. Our results should inform the design of balance exercise program to improve the outcome of the balance training.

Pre-study of Validation of the Children's Eating Behaviour Questionnaire in Korean Children (한국어판 아동식습관 설문지(Korean Children's Eating Behaviour Questionnaire, K-CEBQ)의 타당화 예비연구)

  • Lee, Min-Jeong;Chang, Gyu-Tae;Han, Yun-Jeong
    • The Journal of Pediatrics of Korean Medicine
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    • v.23 no.1
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    • pp.127-140
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    • 2009
  • Objectives In this study, we obtained Korean version of CEBQ (Children's Eating Behaviour Questionnaire) and verify whether it is reliable or not. Methods Total 106 parents completed this questionnaire, and we gathered children's BMI data and examined the relationship between children's BMI and mean scale scores. Results 1. This study results confirmed the theorectical factor structure, with acceptable internal reliability and between-subscale correlations. 2. There are significant mean scale scores difference between anorexia group and control group. 3. There are significant relations between children's BMI and mean scale scores. Conclusions The results support the use of the CEBQ as a phsychometrically sound tool for assessing children's eating behaviours in Korean children.

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Study on the Role Conflict and Professional Attitude of Health Center Nurses (보건소 간호사의 역할갈등과 전문직 태도에 관한 일 연구)

  • Yu, Su-Ok
    • The Korean Nurse
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    • v.29 no.1
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    • pp.72-83
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    • 1990
  • The purpose of this study was to identify role conflict and professional attitude of Health Center nurses for health nursing administration. The data were obtained from 151 nurses of 7 Health Centers in S from July 15 to July 22 1989 using the questiennaires which consisted of 2 scales of role conflict and profess" ional attitude. The data were analyzed by percentage, mean, t-test, ANOVA and Cronbach's $\alpha$ reliability test. The results were as follows. 1) Institutional factor had the highest mean score for the degree of role conflict. The relationship between the degree of role conflict and general characteristics was found to be statistically significant for duty position. (F=2.61, p<.05) 2) Professional educational level had the highest mean score for the professional attitude. The relationship between professional attitude and general characteristics was found to be statistically significant for educational background. (F=4.91, p<.00l), p<.00l)

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Molecular Dynamics Simulations for Transport Coefficients of Liquid Argon : New Approaches

  • Lee, Song-Hi;Park, Dong-Kue;Kang, Dae-Bok
    • Bulletin of the Korean Chemical Society
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    • v.24 no.2
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    • pp.178-182
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    • 2003
  • The stress and the heat-flux auto-correlation functions in the Green-Kubo formulas for shear viscosity and thermal conductivity have non-decaying long-time tails. This problem can be overcome by improving the statistical accuracy by N (number of particles) times, considering the stress and the heat-flux of the system as properties of each particle. The mean square stress and the heat-flux displacements in the Einstein formulas for shear viscosity and thermal conductivity are non linear functions of time since the quantities in the mean square stress and the heat-flux displacements are not continuous under periodic boundary conditions. An alternative to these quantities is to integrate the stress and the heat-flux with respect to time, but the resulting mean square stress and heat-flux displacements are still not linear versus time. This problem can be also overcome by improving the statistical accuracy. The results for transport coefficients of liquid argon obtained are discussed.