• 제목/요약/키워드: Maxillary sinus aspergillosis

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상악동 국균증의 임상적 특성 (CLINICAL CHARACTERIZATION OF THE MAXILLARY SINUS ASPERGILLOSIS)

  • 최희수;윤정훈;김형준;차인호
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제27권3호
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    • pp.271-275
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    • 2001
  • Nine cases of maxillary sinus aspergillosis during a period from February of 1992 to June of 2000 were investigated to analyze the clinical, radiologic and pathologic features. Maxillary sinus aspergillosis is rare disease, but it was increasing tendency with overuse antibiotics, steroid hormones, and anticancer agents. Aspergillosis of the maxillary sinus may occur as a chronic disease in an otherwise healthy person. The clinical features of maxillary sinus aspergillosis were similar to the non-fungal, chronic sinusitis. Intrasinus calcification is known to be a characteristic feature of maxillary sinus aspergillosis. It is suggested that excess root filling materials containing zinc oxide in the maxillary sinus could favour the formation of a local, non-invasive maxillary sinus aspergillosis. And this "dental" model of pathogenensis of maxillary sinus aspergillosis is an alternative to the widely accepted concept of spore inhalation and "aero-genic" pathogenensis of maxillary sinus aspergillosis. The radical surgery such as Caldwell-Luc operation was one of the most effective treatment modalities. Our results of this study indicate that maxillary sinus aspergillosis might occur mainly in healthy individuals rather than debilitating patients. It could efficiently treated with radical surgery alone without the antifungal agents. 4 cases were suspected to be related with teeth extraction and endodontic treatment. There were no recurrence in all cases.

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협부 연부조직을 직접 침습한 상악동 아스페르길루스증 (Direct Aspergillosis Invasion to the Anterior Wall of the Maxillary Sinus: A Case Report)

  • 이중호;이소영;오득영;김상화;이종원;안상태
    • Archives of Plastic Surgery
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    • 제38권5호
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    • pp.691-694
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    • 2011
  • Purpose: With an increase in the population of immunocompromised patients, the incidence of maxillary sinus aspergillus infection has also escalated. Maxillary sinus aspergillosis is generally extended to the sinus antrum, base or thin orbital wall and ethmoid air cell region. We experienced a case of maxillary sinus aspergillosis which was extended directly to the soft tissue of the cheek. Methods: A 46-year-old man with acute myelogenous leukemia was consulted for the defect of the anterior wall of the maxillary sinus, and cheek. Radiologic and histologic findings were consistent with invasive maxillary sinus aspergillosis. The otolaryngology department performed debridement via endoscopic sinus surgery first. Coverage of the resulting defect in the anterior wall of the maxillary sinus and its inner layer was undergone by the plastic and reconstructive surgery department, using a pedicled superficial temporal fascia flap and a split thickness skin graft. The remaining skin defect of the cheek was covered with a local skin flap. Results: The patient went through an uneventful recovery. There was no recurrence during 6 months of follow-up. Conclusion: Maxillary sinus aspergillosis usually involves the orbit or the gingiva but in some cases it may directly invade soft tissues of the cheek. Such an atypical infection extending into the cheek may lead to a large soft tissue defect requiring coverage. Thus, any undiagnosed soft tissue defect involving the cheek or maxillofacial area, especially in immunocompromised patients, should be evaluated for aspergillosis. We present this rare case, with a review of the related literature.

상악동에 발생한 국균증의 치험2례 (TWO CASES REPORT OF MAXILLARY SINUS ASPERGILLOSIS)

  • 김수민;여환호;김영균;김수관;조재오
    • Maxillofacial Plastic and Reconstructive Surgery
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    • 제18권4호
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    • pp.726-733
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    • 1996
  • Aspergillosis of the maxillary sinus was rare disease, but it was increasing tendency with overuse antibiotics, streoid hormones, and anticanncerous agents. The clinical features and X-ray findings are similar to chronic suppurative paranasal sinusitis. Aspergillosis of the maxillary siuses may occur as a chronic diseae in an otherwise healthy person. This infection is usually confined to a single paranasal sinus, the maxillary antrum, though it can involve the orbit and may initiate with findings of proptosis and decreased vision. The disease is characterized by a wide range of initial symptoms, and should be considered as a possible diagnosis in sinusitis refractory to antibiotics and antral lavage. The choice of treatment of this disease is radical surgery and adjunctive systemic antifungal therapy. We experienced a case of right maxillary sinus aspergillosis in a 34 years old male who has dull pain on Rt. zygoma area, and a case of left maxillary sinus aspergillosis in a 30 years old male who had been suffered from nasal stiffness and frontal headache for 3-4 years. We reported two cases with review of literature.

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상악동 국균증의 치험 2례 (CASE REPORT : MAXILLARY SINUS ASPERGILLOSIS)

  • 장용욱;송경호;정진원;이슬기;김좌영;송상훈;양병은;김성곤
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제34권4호
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    • pp.480-484
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    • 2008
  • The incidence of aspergillosis infections in the maxillary sinus has increased recently, because of overuse of antibiotics, steroids, anticancer agents, immunosuppressant, antimetabollites, and uncontrolled diabetes mellitus. The clinical features of maxillary sinus aspergillosis include pain, swelling and foul odor nasal excretion. This needs to be differentiated from bacterial maxillary sinusitis, and surgical treatment with antifungal agents are suggested. Recently, we treated two patients with maxillary sinus aspergillosis surgically (Caldwell Luc operation) and with antifungal agents(itraconazole). The results were satisfactory so we report these cases with literature review.

상악동내 국균증과 편평상피세포암의 동시발생 증례: 조직학적 연구 및 문헌고찰 (Squamous cell carcinoma occurring with aspergillosis in the maxillary sinus: a case report and histological study)

  • 변준호;이정희;노규진;박봉욱
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제36권2호
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    • pp.125-127
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    • 2010
  • The coexistence of aspergillosis and squamous cell carcinoma (SCC) in the maxillary sinus was very rare. To our knowledge, this is the second report of coexistent SCC and aspergillosis in the maxillary sinus. A 58-year-old man underwent surgery for unilateral maxillary sinus infection with oroantral fistula. In the surgical specimen, SCC and aspergillosis were co-detected with routine and immunohistochemical stainings. Moreover, human papillomavirus 18 (HPV-18) was detected by polymerase chain reaction in the sinus specimen. The patient was re-operated with subtotal maxillectomy and has been followed up for two years without any evidence of recurrence or metastasis. Although it is not understood how aspergillosis could induce carcinoma formation, the chronic inflammation caused by prolonged fungal infection might be carcinogenic. Moreover, HPV-16 and -18 were another causative pathogens of SCC in the head and neck region. We recommend careful examination, including preoperative cytology, in patients with maxillary sinus fungal infections because of the potential for cancer development.

상악동에 발생한 aspergilloma에 대한 증례보고 (Aspergilloma of the maxillary sinus: report of a case)

  • 강주한;유재정;김규태;최용석;황의환
    • Imaging Science in Dentistry
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    • 제40권4호
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    • pp.187-189
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    • 2010
  • Aspergilloma of the paranasal sinus is a non-invasive form of aspergillosis, most often in the maxillary sinus. This case presents an 86-year-old female with aspergilloma of the left maxillary sinus. The patient's chief complaint was intermittent pain on the left maxillary first premolar area. A radiopacification of the left maxillary sinus was observed on the panoramic radiograph. Cone-beam computed tomography revealed complete radiopacification of the left maxillary sinus and scattered multiple radiopaque mass inside the lesion. Biopsy was performed under local anesthesia. On microscopic examination, numerous fungal hyphae, which branch at acute angle, were observed. The diagnosis was made as an aspergilloma based on the histopatholgic examination.

원발성 상악동 국균증 치험예 (A CASE REPORT OF PRIMARY MAXILLARY SINUS ASPERGILLOSIS)

  • 오승환;김여갑;류동목;이상철
    • Maxillofacial Plastic and Reconstructive Surgery
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    • 제13권4호
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    • pp.462-467
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    • 1991
  • Aspergillus is a fungus of Ascomycetes class that occurs world wide and found in many of the molds on foods, frutis, grains and plants. Its ubiquitous spores, present in dust, enter the respiratory system of man, where, under proper condition, they become pathogenic. We present a case of primary maxillary sinus aspergillosis developed from a 52-year old male patient when has oroantral fistula after extraction of maxillary Lt. 1st molar tooth. The treatment composed with Caldwell-Luc's operation, Oro-antral fistula closure and associated anit-fungal treatment with Amphoatrisin B.

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Maxillary sinus aspergilloma of odontogenic origin: Report of 2 cases with cone-beam computed tomographic findings and review of the literature

  • Torul, Damla;Yuceer, Ezgi;Sumer, Mahmut;Gun, Seda
    • Imaging Science in Dentistry
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    • 제48권2호
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    • pp.139-145
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    • 2018
  • Aspergilloma of the maxillary sinus is considered rare in immunocompetent patients, but a considerable increase has recently been seen in the incidence of reported cases. Dental procedures involving the antral region are thought to predispose individuals to this form of aspergillosis. Because aspergilloma shares similar clinical features with other sinus pathologies, its diagnosis may be delayed. Thus, an early diagnosis confirmed by a histopathological examination plays a crucial role in the adequate management of aspergilloma. This article provides a concise review of the reported cases of aspergilloma associated with dental procedures and reports 2 new cases of aspergilloma in middle-aged female patients, with a presentation of their cone-beam computed tomographic findings.

당뇨 및 간경변 환자의 상악동과 폐에서 발생한 침윤성 국균증의 치험례 (INVASIVE ASPERGILLOSIS OF THE MAXILLARY ANTRUM AND LUNG IN A PATIENT WITH DIABETES MELLITUS AND LIVER CIRRHOSIS)

  • 김일규;이성준;하수용;주영채;신용운
    • Maxillofacial Plastic and Reconstructive Surgery
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    • 제13권4호
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    • pp.456-461
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    • 1991
  • This is a case report of invasive aspergillosis of the right maxillary antrum and the left lung in a 43 year-old male patient with diabetes mellitus and liver cirrhosis. The results were as follows. 1. Invasive aspergilliosis should be considered in compromised patients who have nasal symptomatology, infraorbital swelling and pain. 2. Invasive aspergillosis is a rapidly progressive mycotic infection of the sinus which may extend to the orbit, nasal cavity and cheek. 3. Surgical intervention is particularly urgent in orbital aspergillosis in patient in whom the eyesight is still preserved. 4. Diagnosis depends upon pathological demonstration of tissue invasion by organism with the typical morphology of aspergillus species. 5. Long-term antifungal drugs should be administrated postoperatively in pathint with invasive aspergillosis.

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인간유두종바이러스 감염과 연관된 구강내 편평상피세포암; 문헌고찰 및 증례보고 (ORAL SQUAMOUS CELL CARCINOMA ASSOCIATED WITH HUMAN PAPILLOMAVIRUS INFECTIONS; TWO CASES REPORT AND REVIEW OF THE LITERATURE)

  • 변준호;박봉욱;이정희;노규진;김종렬
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • 제33권5호
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    • pp.548-553
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    • 2007
  • Several investigators have shown that human papillomavirus(HPV) appear to play an etiologic role in oral and paranasal sinus carcinoma. It was known that 15-25% of head and neck squamous cell carcinoma(SCC) showed HPV-positive infection. Among them, HPV 16 was the most common type but HPV 18 was observed only 2-4% of HPV-positive head and neck cancers. In recent, we treated uncommon 2 oral SCC cases that associated with HPV infection. One is a case of tongue SCC after bone marrow transplantation(BMT), and the other is a case of SCC occurring with aspergillosis in the maxillary sinus. After surgery, HPV 16 and 18 were detected in the surgical specimens by the histological and polymerase chain reaction(PCR) examination. In this report, we present these cases with a review of literature.