• 제목/요약/키워드: Matter of care

검색결과 166건 처리시간 0.03초

Dust particles-induced intracellular Ca2+ signaling and reactive oxygen species in lung fibroblast cell line MRC5

  • Lee, Dong Un;Ji, Min Jeong;Kang, Jung Yun;Kyung, Sun Young;Hong, Jeong Hee
    • The Korean Journal of Physiology and Pharmacology
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    • 제21권3호
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    • pp.327-334
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    • 2017
  • Epidemiologic interest in particulate matter (PM) is growing particularly because of its impact of respiratory health. It has been elucidated that PM evoked inflammatory signal in pulmonary epithelia. However, it has not been established $Ca^{2+}$ signaling mechanisms involved in acute PM-derived signaling in pulmonary fibroblasts. In the present study, we explored dust particles PM modulated intracellular $Ca^{2+}$ signaling and sought to provide a therapeutic strategy by antagonizing PM-induced intracellular $Ca^{2+}$ signaling in human lung fibroblasts MRC5 cells. We demonstrated that PM10, less than $10{\mu}m$, induced intracellular $Ca^{2+}$ signaling, which was mediated by extracellular $Ca^{2+}$. The PM10-mediated intracellular $Ca^{2+}$ signaling was attenuated by antioxidants, phospholipase blockers, polyADPR polymerase 1 inhibitor, and transient receptor potential melastatin 2 (TRPM2) inhibitors. In addition, PM-mediated increases in reactive oxygen species were attenuated by TRPM2 blockers, clotrimazole (CLZ) and N-(p-amylcinnamoyl) anthranilic acid (ACA). Our results showed that PM10 enhanced reactive oxygen species signal by measuring DCF fluorescence and the DCF signal attenuated by both TRPM2 blockers CLZ and ACA. Here, we suggest functional inhibition of TRPM2 channels as a potential therapeutic strategy for modulation of dust particle-mediated signaling and oxidative stress accompanying lung diseases.

신생아 중환자실을 퇴원하는 고위험 환아에서 순차적인 뇌초음파 검사 후 시행한 자기 공명 영상의 유용성 (Usefulness of Magnetic Resonance Imaging after Serial Cranial Ultrasound in the Neonates Graduating Neonatal Intensive Care Unit)

  • 김지혜
    • Investigative Magnetic Resonance Imaging
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    • 제12권2호
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    • pp.170-177
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    • 2008
  • 목적 : 순차적인 뇌초음파 검사 후 신생아 중환자실을 퇴원하는 고위험 환아에서 시행한 자기 공명 영상의 유용성을 알아보고자 하였다. 대상 및 방법 : 총 121명의 신생아에서 시행한 412 초음파와 121 자기공명 영상을 후향적으로 분석하여 초음파 검사에서 발견된 뇌병변과 자기 공명영상에서 발견된 병변을 비교하였다. 뇌병변은 배아기질 출혈 및 뇌실 내 출혈, 그 밖의 여러 출혈과 뇌실질 손상을 중심으로 비교 분석하였다. 결과 : 총 242개의 측뇌실 중 30뇌실의 배아기질 출혈 (GMH)을 초음파로 진단하였고 자기공명영상으로 7개의 GMH를 추가로 진단할 수 있었으며 46개 뇌실의 출혈 (IVH)을 추가로 진단하였다. 출혈의 1/2/3/4 등급은 초음파에서 각각 24/8/13/0 뇌실에서 진단하였고 자기공명영상에서 3/49/10/2 뇌실에서 진단하였다. 그 외에 자기공명영상에서 대뇌 출혈 (4예), 소뇌 출혈(4예), 경막하 및 지주막하 출혈 (8예), 미만성 백질 신호강도 변화 (72예), 조직손실이 없는 작은 실질 병변 (4예), 뇌연화증 (2예), 그리고 뇌실확장 (5예)이 추가로 발견되었다. 결론 : 자기공명영상은 초음파 검사 후 두개강내 출혈과 뇌실질 손상을 추가적으로 진단하는 유용한 검사였으며 특히 뇌실 출혈과 백질 손상의 진단에 우수한 반면 배아기질 출혈은 초음파 추적검사가 더 유용할 것으로 생각한다.

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새로운 건강보험 보장성 강화 대책 1부: 뇌 MRI, 뇌혈관/경부혈관 MRA, 두경부 MRI 급여 확대 (A New Healthcare Policy in Korea Part 1: Expanded Reimbursement Coverage of Brain MRI, Brain/Neck MRA, and Head and Neck MRI by National Health Insurance)

  • 김은희
    • 대한영상의학회지
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    • 제81권5호
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    • pp.1053-1068
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    • 2020
  • 문재인 정부의 새로운 건강보험 보장성 강화 대책에 따라 2018년부터 뇌 MRI, 뇌혈관/경부혈관 MRA, 두경부 MRI 급여가 확대되어 시행 중이다. 2018년 10월부터 2020년 4월까지 개정되어 현재 시행 중인 MRI 급여와 관련된 '요양급여의 적용기준 및 방법에 관한 세부사항'을 중심으로 정리해 보았다. 이 종설은 MRI 요양급여체계, 두통, 어지럼증 환자의 급여기준조정, 뇌 MRI, 뇌혈관/경부혈관 MRA, 두경부 MRI의 급여기준, 표준영상, 판독소견서 등을 포함하였다. 이 글을 통해 영상의학과 전문의가 보험 영역에서도 전문적인 지식을 갖추어 영상의학과 전문의의 전문성을 확보하고, 소속병원에서 주도적인 역할을 하는데 도움이 되고자 한다. MRI 급여화 확대 정책이 진행 중으로 관련 보건복지부의 세부고시가 개정될 수 있다. 따라서 MRI와 보험과 관련된 사안을 지속적으로 업데이트하는 것이 요망된다.

일부 농촌지역의 일차의료이용실태와 그 관련요인에 관한 연구 (A Study on Status of Utilization and The Related Factors of Primary Medical Care in a Rural Area)

  • 위자형
    • 농촌의학ㆍ지역보건
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    • 제20권2호
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    • pp.157-168
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    • 1995
  • This study was carried out, through analyzing the annual reports(year of 1973-1993) on health status of Su Dong-Myun, and specific survey data of 332 households(Su Dong-Myun 209, Byul Nae-Myun 123), located in Nam Yang Ju-Si, Kyung Gi-Do, from July 20 to July 31, 1995, to find out more effective means for primary medical care in a rural area. The results were as fellows : 1. Number of population in Su Dong-Myun was 5,419 in 1973, 4,591(the lowest) in 1987 and 5,707 in 1995. In the composition rate of population, "0-14" of age group showed markedly decreasing tendency from 43.1% in 1975, to 19.1% in 1995, however "65 and over" markedly in creasing tendency form 5.3% in 1975 to 9.8% in 1995. 2. Annual utilization rate per 1,000 inhabitants in Su Dong-Myun showed markedly increasing tendency from 1973 to 1977 such as 343 in 1973, 540 in 1975, 900 in 1977. However, since 1979, the rate showed rapidly decreasing tendency, such as 846 in 1979, 519 in 1985, 190 in 1991 and 1993. 3. The morbid household rate per year was 53.6% of respondents and the rate per 15 days was 48.2%. In disease classification rate of morbid household per year, Arthralgia & Neuralgia was the highest rate(33.9%) and gastro-intestinal disorder(19.3%), Cough(11,9%), Hypertension(7.8%), Accident(3.2%) in next order. 4. In the utilizing facilities for Primary Medical Care, Medical facilities was showed the highest rate(58.1% of respondents) and Pharmacy and Drug Shp(33.1%), Tradition Method(4.0%) in next order. In the Medical facilities, General private clinic was showed the highest rate(34.3%) and specific private Clinic(22.3%), Hospital(19.0%), Health (Sub)center(16.3%), Nurse practitioner (3.3%), Oriental hospital and clinic(2.7%) in next order. 5. Experience rate, utilizing health subcenter was 51.8% of the respondents, and it was 55.0% in Su Dong-Myun and 46.3% in Byul Nae-Myun. In utilization times of health subcenter, times-rate showed next orders such as 1-2 times/6months(31.6%), 1-2 times/year (22.1%), 1-2 times/months(19.2%), 1-2 times/3months(15.6%). 6. In objectives, visiting Health Subcenter, Medical Care was the highest rate(59.8% of the respondents) and health control(23.3%) was in next order. In Medical Care, Primary Care by general physician was higher rate(51.1%) almost all. In the Health control, Immunization too was high rate(18.0%) in health control activities. 7. The reasons rate, utilizing health subcenter showed next order, such as distance to Medical facilities(33.0% of the respondents), Medical Cost(28.1%), Simple process of consultation (10.8%), Effectiveness of cure(7.6%), Function of primary medical care(7.0%) and Attitude of physician(6.5%). 8. In the affecting factors to utilization of primary medical facilities, medical needs was showed the highest rate(29.5% of the respondents) and medical cost(15.4%), distance to medical facilities(14.2%), traffic vehicle(14.2%) and farm work(6.9%) in next order. 9. In the priority between 'daily farm work,' and 'primary medical care', only 46.4% of respondents answered that primary health care is more important than the daily farm work The 22.6% of respondents answered 'daily farm work', and the 12.3% answered 'the equal of the both'. 10. In the criterion of medical facilities choice, medical knowledge and technical quality was showed the highest rate(56.3%), distance or time to medical facilities(10.9%), sincerity and kindness of physician(9.4%), medical cost(8.7%) and traffic vehicle(6.5%) in next order 11. In the advise for improvement of health subcenter function, the 36.1% of respondents answered that 'enforcement of medical personnel and equipment' was required, and then 'improved medical technology'(25.5%), 'good attitude of physician'(14.9%), 'improved medical system'(13.3%), 'enforced drug'(6.7%) in next order. 12. The study on affecting factors to utilization of primary medical facilities was very difficult subject to systematize the analyzed results, due to a prejudice of protocol planner, surveyer and respondent, and variety and overlapping of subject matter.

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치과내원환자들의 의료기관 선택 및 의료서비스 불만요인에 관한 연구 - 서울, 경기, 인천지역을 중심으로 - (A study on patients' choices over dental clinics and factors of complaint against medical service -focused on Seoul, Kyoungi, and Incheon areas)

  • 유은미;김선경;황윤숙
    • 한국치위생학회지
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    • 제8권1호
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    • pp.93-105
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    • 2008
  • In order to provide basic information to help dental medical service with supplying gratifying service for patients. the survey is conducted on the patients who frequently visited dental clinics located in the areas such as Seoul, Kyoungi, and Incheon from May of 2006 to June. The survey results are as following : 1. Judged from the factors to make patients choose one dental clinic over another. the low cost of treatment accounts for 32.8%. and followed by physician's academic background / career experiences with 20.5%. In case of recommending to their acquaintances, physician's proficiency in treatment is ranked high as 56.7%. 2. For most desirable facilities for dental hospitals. the results indicate that cutting-edge medical equipment holds 46.7% and followed by a comfortable waiting room with 32.8%. 3. Examined the questions of what patients are most satisfied with dental clinics. 43.1% of respondents point out kind and detailed explanation. 14.1% also responds to constant care after the treatment. This result suggests that after-care and detailed explanation also play an important role in dental care as well as the treatment itself. 4. For desirable services in the waiting room. 28.5% of the respondents choose a selection of magazines and newspaper and 18.7% say that they want to converse with the staff. As to how long can wait with patience. 38.2% of the participants agree on as long as 20 minutes. 5. Among unsatisfactory sources against dental clinics while visiting, the high cost of the treatment is scored high as 34.1% and followed by a long waiting time with 22.1%. The figure points to the fact that dental medical clinics should consider these two factors to solve in the future. In case where patients find the treatment discontent and they are asked what to do, 36.4% of the respondents respond that they go to a different hospital without saying anything. As to the enquiry about how the complains should be dealt, 46.% wishes that the matter should be taken care immediately upon complaining, 21.8% suggests that they like to feel understood and acceptable when presenting complaints.

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해외 의료케어 전문 영상과 국내 의료케어 영상 비교분석에 관한 연구 (A Study on the Comparative Analysis of Overseas Medical Care Video and Domestic Medical Care Video)

  • 조현경
    • 문화기술의 융합
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    • 제7권4호
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    • pp.415-420
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    • 2021
  • 의료 케어 분야가 다각도로 발전되어가고 있는 상황에서 의료 홍보 영상분석은 중요한 의미를 지닌다. 경쟁력 향상의 문제로 중요성을 있으며 AI 시스템의 가속화 시대는 의료 케어가 가장 선두에 있는 분야이기도 하다. 이에 따른 홍보와 광고 및 설명에 대한 영상의 중요성은 매우 중요하며 기업의 이미지를 전환 시킬 수 있는 중요한 방향이기도 하다. 본 연구에서는 AI 의료 브랜드들의 전문 영상에 대한 비교분석을 중심으로 해외 메이져 회사 2개, 스트라이커와 힐롬 (Stryker, Hill-rom)의 회사와 국내 선두기업 1개(나인벨)의 영상을 중심으로 영상에서의 디자인 특징과 차이점 등을 비교하였고, 그에 따른 세부 파트 분석과 섹션 분석을 하였다. 영상 편집의 기술적 부분 분석으로, 트렌제이션 방식 및 인포 그래픽들을 고찰하였다. 심층 비교는 AI 의료 영상의 영상 색상 톤과 영상 배색 관계에 대한 차이점과 같은점들을 비교 분석하였다. 영상 이미지 결정 부분에 있어서 구체적인 분석은 각 영상들의 영상 인트로 부분과 제품 설명 영상 부분들의 구체적 장면을 가지고, 홍보 디자인에서 나타나고 있는 차별화된 요소들을 비교 연구하였다.

A Case Note on the Medical Negligence of Traditional Chinese Herbal Medicine in the UK

  • Lee, Hai Woong
    • 대한예방한의학회지
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    • 제18권3호
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    • pp.105-115
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    • 2014
  • Objective : Traditional medicine (TM) has been playing its role in national healthcare system and it is taken as complementary and alternative medicine (CAM) from the viewpoint of modern Western medicine. In the UK, not a few practitioners of Traditional Chinese Medicine (TCM) are working as CAM practitioners using herbal medicine and acupuncture therapy. Cases of dispute in the TCM practice are not rare these days because patients who take TCM service are increasing by year. Method : In the UK, dispute cases of the Traditional Medicine of East Asia can be found these days, however, it is hard to find a reported court case. A medical dispute case of TCM will be analysed to see the legal management and the resolving principle in the alternative medicine practice with some cases of Korean Medicine (KM) being discussed. Results : The usual pattern of clinical negligence can be discussed from the points of a duty of care, breach of that duty by negligence, and the harm to the patient from that breach of duty. The judge followed this procedure In this case to discuss the claims. The department of health proposed to introduce regulation to provide the reasonable quality in TCM practice, and the governmental system would be essential to regulate both the TCM practice and practitioners. Conclusion : The dispute case of traditional Chinese herbal medicine (TCHM) practice is important for the clinical negligence in TCHM practice. Judging the negligence of a TCHM practitioner involves the conventional negligence principle in tort law, and the TCHM practitioners are required to keep up with the up-to-date information on the related medical specialty. The reasoning is almost the same as that shown in the court case of Korea. The TCHM practice in the UK needs to be under the regulation by the government. The standard of care we expect of a TCHM practitioner is a further matter to discuss from the healthcare and social viewpoints.

사료 내 새우가용성추출물(shrimp soluble extract) 첨가가 흰다리새우(Litopenaeus vannamei)의 성장, 면역력 및 소화율에 미치는 영향 (Effects of Dietary Supplementation of Shrimp Soluble Extract on Growth Performance, Innate Immunity and Digestibility of Pacific White Shrimp Litopenaeus vannamei)

  • 고대현;신재형;김민기;이초롱;김성삼;박건현;이경준
    • 한국수산과학회지
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    • 제54권3호
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    • pp.287-292
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    • 2021
  • This study was conducted to evaluate the effects of dietary supplementation with shrimp soluble extract (SSE) on growth performance, feed utilization, innate immunity and digestibility of Pacific white shrimp Litopenaeus vannamei. A basal diet (Con) was formulated and three other diets were prepared with SSE supplementation at different levels of 1, 2 and 4% (designated as SSE1, SSE2 and SSE4, respectively). Triplicate groups of shrimp (1.20±0.01 g) were fed one of the experimental diets for 6 weeks. At the end of the feeding trial, growth performance and feed utilization of the shrimp were significantly improved by dietary supplementation of SSE4 compared to those of shrimp fed the Con diet. Shrimp fed SSE4 diet had significantly higher phagocytic activity than shrimp fed the Con diet. Dietary supplementation of SSE improved the protein and dry matter digestibility of shrimp. These results indicate that SSE can be used as a functional additive in the diets for Pacific white shrimp.

영아 쌍둥이 육아 경험에서 어머니가 인식하는 어려움에 대한 질적연구 (A Qualitative Study on Self-perceived Child-rearing Difficulties among Mothers with Infant Twins)

  • 변경애;김은주
    • 한국보육지원학회지
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    • 제9권6호
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    • pp.267-288
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    • 2013
  • 본 연구는 쌍둥이 출산이 증가하는 시대의 흐름에 따라 쌍둥이 자녀를 양육하는 어머니의 육아고충과 어려움에 대한 심층적인 이해를 도모하고, 이에 따른 적절한 지원책을 모색하고자 하는데 목적이 있다. 이를 위해 P시에 거주하며 영아 쌍둥이를 양육하는 어머니 6명을 대상으로, 2012년 12월부터 2013년 8월까지 두 차례의 심층면담을 실시하였다. 연구결과 첫째, 영아 쌍둥이 육아경험에서 어머니가 인식하는 자녀가 겪는 어려움으로는 욕심도 사랑도 나누어야 하는 아이들, 환경의 제약을 받는 아이들, 태생 자체가 약한 아이들로 나타났다. 둘째, 영아 쌍둥이 육아경험에서 어머니가 인식하는 본인의 어려움은 아플 시간도 없는 엄마, 몸도 마음도 쓸쓸한 엄마, 경제적 부담을 힘들어 하는 엄마로 나타났다. 이를 위해 쌍둥이에 대한 사회적 인식의 변화와 정서적, 경제적 지원 시스템이 구축되어야 할 것을 제안한다. 본 연구의 결과는 향후 쌍둥이 육아지원의 활성화를 돕는 기초자료가 될 수 있을 것이다.

일상생활활동과 삶의 질에 대한 치매노인과 요양보호사의 지각 차이에 대한 연구 (Study of Difference on Activities of Daily Living and Quality of Life of Dementia Patients Reported by Dementia Patients and Caregivers)

  • 송민선;최찬헌
    • 동의생리병리학회지
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    • 제26권3호
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    • pp.386-391
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    • 2012
  • The purposes of this study were to investigate the difference on activities of daily living(ADL), instrumental activities daily of living(IADL) and quality of life of aged woman with dementia reported by aged woman with dementia and caregivers. From December 2009 to February 2010, 64 subjects in the institutionalized aged woman with dementia, 22 caregivers were surveyed through structured questionnaires. There was no difference ADL and quality of life of aged woman with dementia reported by aged woman with dementia and caregivers. But, there was significant differences in IADL. Also, ADL was positively related to IADL in aged woman with dementia and caregivers. ADL and IADL were negatively related to quality of life in aged woman with dementia and caregivers. In daily activity and life quality, there is no difference recognized by aged woman with dementia and caregivers. So it's not matter for the nursery to recognize the demand of the aged woman with dementia and to care them. It is necessary to study the elderly with dementia at home, and to compare the patients in accordance with severity.