• The Korean Journal of Community Living Science
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• v.16 no.4
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• pp.71-81
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• 2005

The purpose of this research was to delineate the effect of maternal parenting stress and verbal abuse on emotional maladjustment behaviors in children. The sample consisted of 542 pairs of fifth/sixth graders and seventh/eighth graders, and their mothers. The major findings of the research were as follows: First, looking at the correlation between the mother's age/education level and the maternal parenting stress level, the maternal parenting stress level factor showed differences correlating to the mother's education level. Second, looking at the correlation between the mother's age/education level and the verbal abuse, the verbal abuse factor showed differences correlating to the mother's age/education level. Third, looking at the correlation between the maternal parenting stress level and the verbal abuse, the verbal abuse factor showed differences correlating to the maternal parenting stress level. Forth, the result of multiple regression analysis on the effects of the maternal parenting stress and verbal abuse on the children's emotional maladjustment behaviors indicated that verbal abuse was the significant contributing factor.

• Korean Journal of Child Studies
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• v.34 no.6
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• pp.77-96
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• 2013

The purpose of this study was to examine the relationships among mother's psychological characteristics(self-esteem, self-efficacy, and depression), parenting related factors(maternal parenting stress and mother's knowledge on infant development), maternal parenting style, and two-year-old infants' development. The participants consisted of 1735 mothers and their two-year old infants selected from a sample of the 3rd Panel Study of Korean Children(PSKC) by the Korea Institute of Child Care and Education(KICCE), conducted in 2010. Data were analyzed by means of a Structural Equation Model(SEM) to identify the structure and relationships among the various factors. The significance of direct and indirect effects to test the mediating effect of maternal parenting style were identified via bootstrapping. The results indicated that maternal parenting style most definitely mediated the relationship among the mother's psychological characteristics(self-esteem and self-efficacy), parenting related factors(maternal parenting stress and mother's knowledge on Infant development) and the development of their two-year-old infants.

• The Korean Journal of Physiology
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• v.11 no.2
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• pp.63-66
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• 1977

Motor vehicles are the major source of environmental air pollution through the combustion of lead-containing gasolines. People who live in the areas with heavy traffic usually have the higher blood lead levels. This study was to investigate the lead level between the maternal blood and their infants cord blood. Immediatly after Placental delivary, the sampls of cord blood and maternal venous blood were obtained randomly from 14 infants whose mothers had spent their entire pregnancy in Seoul. Lead concentration was determined by the dithizone method. The results obtained were summarized as follows: 1. Hemoglobin, Hct and RBC were significantly higher in cord blood than in the maternal blood, by 36%, 54.9%, 36.9% respectively. 2. MCV in cord blood was higher than that in maternal blood by 13.8%. But MCH and MCHC were lower than those in maternal blood, by 9.7%, 3.3% respectively. The differences were statistically significant. 3. Lead concentration of cord blood $(23.93\;{\mu}g%)$ was higher than that in maternal blood $(21.93\;{\mu}%)$ by 9.1%.

• Korean Journal of Community Nutrition
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• v.3 no.4
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• pp.565-573
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• 1998

Iron deficiency anemia in pregnant women has been of great concern because of its negative effects on the outcomes of pregnancy. Much of evidence has shown that there are associations between pregnancy outcomes and maternal iron status. Maternal iron status might affect pregnancy outcomes through the iron status of the cord blood. In this study, we divided 91 subjects into two groups : the anemic and the normal groups. The groups were classified according to their hemoglobin(Hb) and hematocrit(Hct) values of the maternal blood in the third trimester of the pregnancies. We determined the parameters for the iron status of the cord blood and then analyzed the correlations between these parameters and the pregnancy outcomes. Mothers in the anemic group had a significantly higher parity number and a lower dietary score as well as a shorter duration of iron supplements consumed compared to those in the normal group. Maternal Hb values in the third trimester had positive correlations with the infant's head and chest circumferences, and the Hct values related positively to the infant's chest circumferences. On the other hand, Hb concentrations of the cord blood had positive correlations with the infant's height and head and chest circumferences. The Hct values of the cord blood had positive correlations with gestational periods and the cord lengths. These results suggest that the maternal iron status might influence fetal development through the iron status of the cord blood.

• Women's Health Nursing
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• v.12 no.3
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• pp.231-239
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• 2006

Purpose: This study was done to investigate differences in maternal role confidence and parenting stress according to the infant's feeding method. Method: The participants were 257 mothers of infants aged 5$\sim$7 months. 145 breast-feeding mothers and 112 bottle-feeding mothers participated. The Maternal Role Confidence Scale and Parenting Stress Index(PSI) were used. Results: The score of maternal role confidence of breast-feeding mothers (3.28) was significantly higher than that of bottle-feeding mothers(2.84). In addition, the parenting stress level of breast-feeding mothers(1.80) was lower than that of bottle-feeding mothers(2.97). However, the scores of maternal role confidence and the parenting stress level were not different according to the mother's and infant's personality characteristics. There was a significant negative correlation between the score of maternal role confidence and parenting stress levels(r=-.55, p<.001). Conclusion: Breast feeding mothers had more confidence of their maternal role, and a lower parenting stress level. Therefore, nurses must encourage infant mothers to breast feed since it is the best option for mothers as well as infants.

• International Journal of Advanced Culture Technology
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• v.9 no.3
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• pp.16-22
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• 2021

This study was phenomenological analysis of maternal nursing of online practice experience. The study participants were students in between the ages of 20 to 25 who participated in the online practice of maternal nursing and conducted to a total of three interviews until the meaning were no longer derived. The data collection period was from May 26 to June 5, 2021, and analysis was conducted simultaneously with the datas have collected. The collected data were analyzed using the Giorgi's Phenomenological Analysis Method, and the study resulted in five categories (Opportunity to repeat, Systematic Scenarios, Immediate nursing intervention feedback, Beneficial hands-on experience, Different case experiences), 11 subcomponents, and 21 Semantic units. Based on the results of this study, the following conclusions were obtained. In maternal nursing, nursing students could experience more systematic and diverse case online than experiences throughout clinical practice, and achievement was also increased in theory learning for online practice. In other words, the online practice of maternal nursing was suitable for various content compositions that could not be experienced in clinical practice, but it is deemed urgent to have a program in Korean suitable for Korean culture. In future studies, this researcher hope to produce a maternal nursing practice program in Korean.

• Genes and Genomics
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• v.40 no.12
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• pp.1339-1349
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• 2018

Cerebral palsy (CP) is a non-progressive neurological disease, of which susceptibility is linked to genetic and environmental risk factors. More and more studies have shown that CP might be caused by multiple genetic factors, similar to other neurodevelopmental disorders. Due to the high genetic heterogeneity of CP, we focused on investigating related molecular pathways. Ten children with CP were collected for whole-exome sequencing by next-generation sequencing (NGS) technology. Customized processes were used to identify potential pathogenic pathways and variants. Three pathways (axon guidance, transmission across chemical synapses, protein-protein interactions at synapses) with twenty-three genes were identified to be highly correlated with CP. This study showed that the three pathways associated with CP might be the molecular mechanism of pathogenesis. These findings could provide useful clues for developing pathway-based pharmacotherapies. Further studies are required to confirm potential roles for these pathways in the pathogenesis of CP.

• Research in Community and Public Health Nursing
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• v.32 no.1
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• pp.116-129
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• 2021

Purpose: This study aimed to investigate the maternal health effects of internet-based education interventions on parturients during the postpartum period through a systematic review of randomized controlled trials. Methods: An electronic literature search of the Cochrane Library, CINAHL, EMBASE, Eric, PsycINFO, PubMed, RISS, and KISS databases was performed, using the combination of keywords such as 'parenthood education', '*natal education', '*birth intervention', 'internet-based intervention', 'randomized controlled trial'. The inclusion criteria were peer-reviewed papers in English regarding randomized controlled trials of internet-based postnatal education interventions. Educational interventions were delivered through any web, mobile, eHealth, mHealth, virtual reality, short message service, or social networking service platform. Quality appraisal was performed using the Risk of Bias 2 (RoB 2) for randomized controlled trials. Nine articles were yielded, and the intervention effects were analyzed. Results: Internet-based education interventions during the postpartum period affect maternal self-efficacy, postpartum depression, and successive breastfeeding; however, they do not affect maternal satisfaction and parenting confidence. Conclusion: This study demonstrated that internet-based education interventions affect maternal health status in terms of psychological, emotional, and physical wellness. Therefore, maternal health care professionals can utilize remote education using the internet or mobile-based interventions during the postpartum period.

• Child Health Nursing Research
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• v.20 no.4
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• pp.247-254
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• 2014

Purpose: Maternal-fetal attachment in a pregnant woman is important for her health and for her child's emotional stability. This study was done to identify the contribution of maternal fatigue, social support, and Taegyo to maternal-fetal attachment based on a survey of pregnant women. Methods: The study was a descriptive correlation study. Participants were 211 from two women's health clinic centers. Data were analyzed using t-test, ANOVA, Pearson correlation coefficients and stepwise multiple regression. Results: Mean scores for maternal-fetal attachment, Taegyo, maternal fatigue, and social support were 93.74 (range 25-125), 64.76 (17-85), 24.12 (10-40), and 54.43 (22-132), respectively. There were significant differences in maternal-fetal attachment according to parity, breast feeding experience, and putting prenatal education into practice. Multiple regression analysis showed that the key determinants of maternal-fetal attachment, were Taegyo (${\beta}$=.67), maternal fatigue (${\beta}$=.21), and social support (${\beta}$=.13), and these explained 55% of the total variance of attachment. Conclusion: The results suggest a need to encourage Taegyo in prenatal management program and provide methods for fatigue resolution and promotion of social support.

• Journal of Microbiology and Biotechnology
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• v.33 no.9
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• pp.1213-1227
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• 2023

Fetal growth restriction (FGR) is a prevalent obstetric condition. This study aimed to investigate the role of Toll-like receptor 9 (TLR9) in regulating the inflammatory response and gut microbiota structure in FGR. An FGR animal model was established in rats, and ODN1668 and hydroxychloroquine (HCQ) were administered. Changes in gut microbiota structure were assessed using 16S rRNA sequencing, and fecal microbiota transplantation (FMT) was conducted. HTR-8/Svneo cells were treated with ODN1668 and HCQ to evaluate cell growth. Histopathological analysis was performed, and relative factor levels were measured. The results showed that FGR rats exhibited elevated levels of TLR9 and myeloid differentiating primary response gene 88 (MyD88). In vitro experiments demonstrated that TLR9 inhibited trophoblast cell proliferation and invasion. TLR9 upregulated lipopolysaccharide (LPS), LPS-binding protein (LBP), interleukin (IL)-1β and tumor necrosis factor (TNF)-α while downregulating IL-10. TLR9 activated the TARF3-TBK1-IRF3 signaling pathway. In vivo experiments showed HCQ reduced inflammation in FGR rats, and the relative cytokine expression followed a similar trend to that observed in vitro. TLR9 stimulated neutrophil activation. HCQ in FGR rats resulted in changes in the abundance of Eubacterium_coprostanoligenes_group at the family level and the abundance of Eubacterium_coprostanoligenes_group and Bacteroides at the genus level. TLR9 and associated inflammatory factors were correlated with Bacteroides, Prevotella, Streptococcus, and Prevotellaceae_Ga6A1_group. FMT from FGR rats interfered with the therapeutic effects of HCQ. In conclusion, our findings suggest that TLR9 regulates the inflammatory response and gut microbiota structure in FGR, providing new insights into the pathogenesis of FGR and suggesting potential therapeutic interventions.