• Title/Summary/Keyword: Material Filling

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Bone Formation Effect of the RGD-bioconjugated Mussel Adhesive Proteins Composite Hydroxypropyl Methylcellulose Hydrogel Based Nano Hydroxyapatite and Collagen Membrane in Rabbits

  • Kim, Dong-Myong;Kim, Hyun-Cho;Yeun, Chang-Ho;Lee, Che-Hyun;Lee, Un-Yun;Lim, Hun-Yu;Chang, Young-An;Kim, Young-Dae;Choi, Sung-Ju;Lee, Chong-Suk;Cha, Hyung Joon
    • Journal of Marine Bioscience and Biotechnology
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    • v.7 no.2
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    • pp.58-70
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    • 2015
  • Injectable RGD-bioconjugated Mussel Adhesive Proteins (RGD-MAPs) composite hydroxypropyl methylcellulose (HPMC) hydrogels provide local periodontal tissue for bone filling in periodontal surgery. Previously we developed a novel type of injectable self-supported hydrogel (2 mg/ml of RGD-MAPs/HPMC) based porcine nano hydroxyapatite (MPH) for dental graft, which could good handling property, biodegradation or biocompatibility with the hydrogel disassembly and provided efficient cell adhesion activity and no inflammatory responses. Herein, the aim of this work was to evaluate bone formation following implantation of MPH and collagen membrane in rabbit calvarial defects. Eight male New Zealand rabbits were used and four circular calvarial defects were created on each animal. Defects were filled with different graft materials: 1) collagen membrane, 2) collagen membrane with MPH, 3) collagen membrane with bovine bone hydroxyapatite (BBH), and 4) control. The animals were sacrificed after 2 and 8 weeks of healing periods for histologic analysis. Both sites receiving MPH and BBH showed statistically increased augmented volume and new bone formation (p < 0.05). However, there was no statistical difference in new bone formation between the MPH, BBH and collagen membrane group at all healing periods. Within the limits of this study, collagen membrane with MPH was an effective material for bone formation and space maintaining in rabbit calvarial defects.

The Primary Structure Controlled Mineralization in Weolseong Diatreme, Southern Korea (월성(月城) 다이아튜림의 층준(層準)에 따른 광화(鑛化) 현상(現狀))

  • Park, Ki-Hwa;Oh, Mihn-Soo
    • Economic and Environmental Geology
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    • v.20 no.1
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    • pp.19-34
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    • 1987
  • The Nokdong As-Zn deposit, located 28 km south of Kyeongju City, Southern Korea, has been investigated by a deep drilling programme. The mineralized zone is roughly 290m long and 180m wide at surface and is hosted in a pipe diatreme infilled with poor to well bedded felsic volcaniclastics. The diatreme was formed by explosive volcanic activity, of probably early Tertiary age, subsequent hydrothermal alteration and mineralization took place concurrently within stratigraphic layers in diatreme. Coarse volcaniclastics in the center part of the diatreme, together with complex systems of fracturing, acted as pathways for late hydrothermal fluids which caused alteration of volcanic material to sericite, chlorite and carbonate and precipitated ore minerals, quartz and calcite in the voids. Porosity and permeability were key factors in determining which portions of the layered diatreme were mineralized. The lower part of certain layers retained a relatively high porosity and were extensively mineralized. Metallic mineralization, consisting mostly of pyirte, sphalerite and arsenopyrite, is found as disseminations, tuff-breccia filling and veins.

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Microscopic Study of Sangdong Tungsten Ore Deposit, Korea (상동중석광상(上東重石鑛床)의 현미경적(顯微鏡的) 연구(硏究))

  • Lee, Dai Sung;Kim, Suh-Woon
    • Economic and Environmental Geology
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    • v.2 no.1
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    • pp.1-12
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    • 1969
  • In the Sangdong Mine area, Taebaegsan series (Pre-Cambrian) and Chosun System (Cambro-ordovician) are widely distributed. The Chosun System consists of Yangdug Series (Jangsan Quartzite and Myobong Slate) and The Great Limestone Series (Pungchon Limestone, Shesong Shale, Hwajeol Formation and Dongjeom Quartzite). The mineralized zone containing the main ore body of the Sangdong Mine was developed in the Myobong Slate formation. The result of the field and microscopic study on the mineral paragenesis and it's wall rock alteration in the tungsten ore deposit shows the following features. The orogenic movements of the Post-Chosun System in the Hambaeg Geosyncline are closely related to the tungsten ore deposition in the area, the ore minerals are composed mainly of scheelite, powelite molybdenite and sulfide minerals, and gangue minerals are hornblende, diopside, garnet, quartz, phlogopite, tremolite, biotite, muscovite, fluorite, etc., main ore body was enriched by scheelite bearing quartz vein filling into interstices of formerly mineralized zones, and the minor faults, faults of N $60^{\circ}-70^{\circ}W$, $45^{\circ}-60^{\circ}NE$ and joints, which were formed at the end of the mineralization and the slate. Country rock of the ore body was altered into the following several zones from the outside to the inside; lowgrade recrystalline aureole, silicified sericite zone, and diopside-hornblende zone. Under the microscopic observation of 195 samples taken from throughout ore body can be classified into 10 different groups by their mineral paragenesis as shown in table 2. The garnet-diopside group is primary skarn and it shows gradational change to the groups of later stage by the successive processes of metasomatism. From the stage of quartz-bearing group, the dissemination of scheelite is seen. The crystallization of scheelite in the bed started with the quartz deposition and continued to the last stage when quartz vein intruded into the main ore body. In the field and the under ground investigation a durable limestone bed in thickeness about 20 meters and their remnants in ore body are observed and under microscope calcite remnants are recognized. Hence it is posturated that the ore material moved up through the faults, shear zones or feather cracks and was assimilated with the interbeded limestone, after that the body was affected by the successive differentiated ore solution by gradational increasing in $SiO_2$, $K_2O$ and $H_2O$. Evidently this ore deposit shows the features resulted from pyrometasomatic processes.

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Two Cases of Silicone-induced Pulmonary Embolism (Silicon 주사후 발생한 폐색전증 2예)

  • Jung, Bock-Hyun;Suh, Young-Ill;Lee, Jae-Myoung;Song, Sook-Hee;Kim, Ho-Joong;Lee, Myoung-Koo;Hyun, In-Gyu;Jung, Ki-Suck;Shin, Hyung-Sick
    • Tuberculosis and Respiratory Diseases
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    • v.40 no.5
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    • pp.610-615
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    • 1993
  • Silicone (polydimethylsiloxane) has widely been used in breast augmentation and other cosmetic procedures. Despite the stability of its chemical nature, local and systemic adverse reactions associated with silicone have been reported. There were several patients who suffered from pulmonary embolism associated with injection of silicone. Silicone-induced pneumonitis and sudden death after subcutaneous injection of silicone has been also described. However, there is no case in the literature of clinically diagnosed silicone-induced pulmonary embolism in Korea. We experienced 2 women who developed respiratory symptoms after illicit subcutaneous injection of silicone for the purpose of colporrhaphy. One patient was admitted because of dyspnea, chest pain, hemoptysis and bilateral pulmonary infiltration after repeated injection of silicone. Pulmonary function test initially showed severe restrictive pattern and transbronchial lung biopsy disclosed numerous oil-like material filling the alveolar septal capillaries and macrophages. High resolution C. T., bronchoalveolar lavage, transbronchial lung biopsy and pulmonary angiogram disclosed abnormalities compatible with silicone fluid-induced pulmonary embolism. The other patient expired shortly after arrival in the emergency room. It is suggested that illicit injecion of silicone fluid carries serious respiratory problems and can induce pulmonary embolism followed by acute respiratory failure.

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Effect of Calcium Hydroxide on the Microhardness of Root Dentin of Primary Tooth (수산화칼슘 근관충전제의 적용이 유치 치근상아질의 미세경도에 미치는 영향)

  • Jun, Saeromi;Kim, Jong-Bin;Yoo, Seung-Hoon
    • Journal of the korean academy of Pediatric Dentistry
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    • v.40 no.3
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    • pp.177-184
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    • 2013
  • Calcium hydroxide mixture medicaments can nearly be considered to be the ideal primary tooth filling material. However, long-term application of calcium hydroxide combinations as an intra canal medicament softens dentin. The aim of this study was to evaluate the effect of calcium hydroxide on the microhardness of root dentin of primary tooth. For the study, 60 extractedprimary incisors were divided into 3 groups (no medicament, calcium hydroxide/iodorform mixture, and calcium hydroxide/distilled water mixture). After the cleansing and shaping of canals, calcium hydroxide medicaments were applied and stored for different periods of time (1, 7, 30, 90 days). The root was horizontally sectioned into 2 mm thick specimens and the microhardness was measured using Vickers microhardness tester. The results were as follows : Root dentin microhardness of primary teeth decreased with long term exposure to calcium hydroxide medicaments according to the experimental period and showed statistically significance (p < 0.05). Root dentin microhardness of primary tooth filled with calcium hydroxide mixed with distilled water showed more decrease than filled with Vitapex and showed statistically significance (p < 0.05). Root dentin microhardness of a control group without exposure to calcium hydroxide decreased according to the experimental period and showed statistically significance (p < 0.05).

Physical Properties Analysis for Automated Process Design of Solar Salts (천일염 자동화 공정설계를 위한 물리적특성 분석)

  • Kim, Hoon;Kim, Woong;Lee, Hyo-Jae;Han, Jae-Woong
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.11 no.4
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    • pp.408-413
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    • 2018
  • In this paper, the particle size, bulk density, friction coefficient and angle of repose were measured for the automatic processing of solar salt, which was classified with 5 levels of moisture content (16.5, 13.2, 8.2, 4.9, 3.7%). Average diameter was 1.98~1.60mm according to moisture content, and bulk density increased with increasing moisture content. As a result of measuring the coefficient of dynamic friction, the maximum value was shown in the stainless steel plate according to the material, and ABS plate and acrylic plate were lower in the order. Movement occurred at the moisture content of 8.2% or less, and the empty angle of repose was increased and the filling angle of repose was decreased as the moisture content increased.

A study on development of CRM by means of XRF analysis for fine ceramic ($BaTiO_3$) (티탄산바륨 소재의 XRF 분석용 CRM 개발에 관한 연구)

  • Kim, Young Man;Jeong, Chan Yee;Lim, Chang Ho;Song, Taek Yong;Lee, Dong Soo
    • Analytical Science and Technology
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    • v.9 no.4
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    • pp.382-391
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    • 1996
  • In this study, 12 different chemical species of fine ceramic($BaTiO_3$) were synthesized as the standard materials for the fast and accurate measurements of X-ray fluorescence spectrometry. Samples were diluted to sixteen times with the filling compound ($Li_2B_4O_7+LiBO_2$) in order to remove the matrix effect, and to get the convenient storage and homogeneity of ingredients. The matrix effects among the ingredients were corrected by the empirical coefficient method based on the Lucas-Tooth and Price model. The standard curve on 12 standard materials containing 15 elements were obtained by using X-ray fluorescence spectrometry at three different laboratories. The correlation factors of BaO, PbO, SrO, $Fe_2O_3$, $La_2O_3$, $SnO_2$, ZnO, $ZrO_2$, CaO indicated the relati vely good agreement over 0.995 among the three different laboratories. $SiO_2$ and $Al_2O_3$ showed the poor linearity because of their low fluorescence intensities.

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A study on the development of SRM for XRF analysis of PZT[$Pb(ZrTi)O_3$] (PZT[$Pb(ZrTi)O_3$]의 XRF 분석용 SRM 개발에 관한 연구)

  • Kim, Young Man;Jeong, Chan Yee;Lim, Chang Ho;Choi, Beom Suk
    • Analytical Science and Technology
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    • v.10 no.6
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    • pp.439-444
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    • 1997
  • Twelve kinds (1set) standard materials of chemical ingredients of lead zirconate titanate[$Pb(ZrTi)O_3$] have been developed in order to determine fast and accurate measurement of X-ray fluorescence spectrometry. Especially, we used diluted(ahout sixteen times) filling compound($Li_2B_4O_7/LiBO_2=4/1$) to consider removal effect of matrix, storage convenience, and homogenous characteristics. As a result from the four different laboratories, we obtained extremly good agreement about the standard curve on twelve standard materials which containing eleven elements, PbO, $ZrO_2$, $TiO_2$, SrO, $WO_3$, $La_2O_3$, $Cr_2O_3$, MgO, $Nb_2O_5$, and $MnO_2$. The correlation factor of standard curve was over 0.998. However, ZnO has relatively low correlation factor, 0.977, because the concentration was 10ppm lower than other original materials. This analysis reveals that ZnO has shown the poor linearity as well as low fluorescence intensity. In present work, XRF standard materials are useful for determining a rapid and accurate results for major and minor elements concentration among PZT.

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Applicability of Particle Crushing Model by Using PFC (PFC를 이용한 입자 파쇄 모델의 적용성 연구)

  • Jeong, Sun-Ah;Kim, Eun-Kyung;Lee, Seok-Won
    • Journal of the Korean Geosynthetics Society
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    • v.9 no.1
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    • pp.47-57
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    • 2010
  • Granular soils having a large particle size have been used as a filling material in the construction of foundation, harbor, dam, and so on. Consequently, the shear behavior of this granular soil plays a key role in respect of stability of structures. For example, soil particle crushing occurring at the interface between structure and soil and/or within soil mass can cause a disturbance of ground characteristics and consequently induce issues in respect of stability of structures. In order to investigate the shear behavior according to an existence and nonexistence of particle crushing, numerical analyses were conducted by using the DEM (Discrete Element Method)-based software program PFC2D (Particle Flow Code). By dividing soil particle bonding model into crushing model and noncrushing model, total four particle bonding models were simulated and their results were compared. Noncrushing model included one ball model and clump model, and crushing model included cluster model and Lobo-crushing model. The combinations of soil particle followed the research results of Lobo-Guerrero and Vallejo (2005) which were composed of eight circles. The results showed that the friction angle was in order of clump model > cluster model > one ball model. The particle bonding model compared to one ball model and noncrushing model compared to crushing model showed higher shear strength. It was also concluded that the model suggested by Lobo-Guerrero and Vallejo (2005) is not appropriate to simulate the soil particle crushing.

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A Study on the Development of Large Aluminum Flange Using Casting/Forging Process (주조/단조 기술을 이용한 대형 알루미늄 플랜지 개발에 관한 연구)

  • Bae, Won-Byeong;Wang, Sin-Il;Seo, Myeong-Gyu;Jo, Jong-Rae
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.25 no.9
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    • pp.1438-1443
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    • 2001
  • The significance of the casting/forging process for reducing the production cost of large components is being noted in these days. This casting/forging process is a method of forging a workpiece preformed by casting into the final shape. In this study, the casting/forging process has been applied in manufacturing a large aluminum flange in order to reduce press capacity and material cost. Firstly, a hot compression test was performed with cast cylindrical billets in order to determine the optimum forging condition of the aluminum flange. The optimum range of forging temperature of Al 5083 was from 420$\^{C}$ to 450$\^{C}$. The suitable strain rate was 1.5 sec(sup)-1. The deformation amount of a preform of a preform in a forging process is a key role in the mechanical properties of casting/forging products. In order to find the change of mechanical properties according to effective stain of cast aluminum billets, a hot upsetting test were performed with rectangular blocks and then a uniaxial tensile test was performed with specimens cut from the upsetted billets. The tensile strength and the elongation of cast/upsetted aluminum billets were increased largely until the effective strain was 0.7. FE analysis was performed to determine the configurations of case preform and die for an aluminum flange. In the FE analysis, the forging load-limit was fixed 1500ton for low equipment cost. The cast preform was designed so that the effective stain around the neck of a flange exceeded 0.7. From the result of FE analysis, optimal configurations of the cast preform and the die were designed for a large flange. The filling and solidification analysis for a sound cast-preform was carried out with MAGMA soft. In the forging experiment for an aluminum flange, it was confirmed that the optimal configuration of the cast preform predicted by FE analysis was very useful. The cast/forged products using designed preform were made perfectly without any defects.