• 대한두경부종양학회지
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• 제38권1호
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• pp.49-52
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• 2022

Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) is a low-grade B-cell lymphoma that typically follows an indolent clinical course. It occurs in a variety of mucosal linings extranodal tissue, most commonly in the stomach. Other commonly involved sites include other parts of the gastrointestinal tract, thyroid, salivary gland, lung, lacrimal gland, synovium, dura mater, breast, skin, and eyes. It occurs very rarely in the buccal mucosa. A 50-year-old man came to the clinic while presenting a 5-month history of right-sided buccal mass. The incisional biopsy did not confirm the diagnosis of the lesion. He underwent complete excision of buccal mass for the diagnosis and treatment. The final pathology confirmed MALT lymphoma immunohistochemically. After surgery, he received radiotherapy with 30.6 Gy. There is no recurrence for 8 months after treatment. Herein we report a rare case of buccal MALT lymphoma with a review of the literature.

• Journal of Korean Dental Science
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• 제9권1호
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• pp.35-41
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• 2016

Langerhans cell histiocytosis (LCH) is characterized by proliferation of histiocyte-like cells (Langerhans cell histiocytes) with characteristic Birbeck granules, accompanied by other inflammatory cells. Treatments of LCH include surgery, chemotherapy, and radiotherapy. One of the representative forms of chemotherapy is intralesional injection of steroids. Surgical treatment in the form of simple excision, curettage, or even ostectomy can be performed depending on the extent of involvement. Radiotherapy is suggested in case of local recurrence, or a widespread lesion. This article shows the case of repetitively recurrent LCH of a 56-year-old man who had been through surgical excision and had to have marginal mandibulectomy and radiotherapy when the disease recurred. After the first recurrence occurred, lesions involved the extensive part of the mandible causing pathologic fracture, so partial mandibular bone resection was performed from the right molar area to the left molar area followed by the excision of the surrounding infected soft tissues. The resected mandibular bone was reconstructed with a segment of fibula osteomyocutaneous free flap and overdenture prosthesis supported by osseointegrated implants.

• Radiation Oncology Journal
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• 제11권2호
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• pp.411-419
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• 1993

A total of 44 patients with extremity soft tissue sarcomas had received conservative surgery and radiation therapy in the Department of Radiation Oncology, Yonsei Cancer Center, Yonsei University College of Medicine between Jan. 1980 and Dec. 1990. Initial surgical treatment consisted of intracapsular excision in 33 patients $(75\%),$ marginal excision in 9 patients, and wide excision in two patients. Total radiation doses were between 40Gy and 65Gy (median 60 Gy). Median follow-up period was 47 months. Overall actuarial 5-year survival rate was $76.9\%$ and 5-year recurrence free survival rate was $39.3\%.$ There was no statistically significant prognostic factors but the 5-year survival rates tended to be decreased in the patients with high grade tumors and treated with narrow surgical extent. Sixteen patients recurred during fellow-up (16/31, $51.6\%).$ The incidence of initial local recurrence was $22.6\%$ (7/31) and distant metastasis was $29\%(9/31).$ Of the 7 who did not have metastasis at diagnosis of local recurrence, 5 were submitted to a salvage treatment. All of them achieved local control and distant metastasis appeared in three of them. In conclusion, conservative surgery and radiation therapy in the patients with extremity soft tissue sarcomas was the effective treatment modality.

• 대한골관절종양학회지
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• 제7권1호
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• pp.20-27
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• 2001

목적 : 건초에서 생긴 거대세포종은 수부에서 발생하는 종양 중 두 번째로 흔하나 절제술 후에 재발이 드물지 않으며 국내에서의 연구는 많지 않다. 이에, 저자들은 완관절부를 포함한 수부에 생기는 건초의 거대세포종의 임상적 특성과 수술적 치료후 결과를 분석하여 문헌고찰과 함께 보고하고자 한다. 대상 및 방법 : 1991년부터 1998년까지 수부에서 발생한 종물로 절제생검술을 시행받은 환자 중 조직병리학적으로 건초의 거대세포종으로 진단받은 총 38명, 41예에 대해 성별, 나이, 증상, 증상발현기, 종양이 발생한 부위, 발생한 건, 크기, 다발성 여부, 양측성 여부, 방사선학적 소견 및 골 침범, 재발여부 등에 대해 분석하였으며, 추시기간은 평균 13.1개월(5~40개월)이었다. 결과 : 38명 중 여자에서 29명으로 빈발하였고, 발생연령은 6세에서 66세까지 다양하였으나 50대에서 12례로 가장 호발하였으며 평균연령은 40.1세였다. 지배수지와 비지배수지의 발생경향은 비슷하였고(17례:21례), 모두 일측성이었다. 신전건(17례)보다 굴곡건(24례)에서 더 호발하였으며 증상발현기는 2개월에서 120개월(평균 23.4개월)이었다. 증상으로 대부분 무통성 종물을 호소하였으나, 5례에서 압통, 36례에서 운동장애, 5례에서 압박에 의한 신경증상을 호소하기도 하였다. 재발을 주소로 내원한 경우가 3례였다. 부위별 발생빈도는 수지에서 36례, 수장부에서 3례, 완관절부위 장측에서 2례 순으로 빈발하였으며, 수지별 발생빈도는 인지에서 14례(34%)로 가장 많았고, 엄지가 10례(24%), 중지는 9례, 환지는 5례, 소지는 3례의 빈도순을 보였다. 수지상 발생부위는 원위지골간 관절부 및 중위지골부에서 20례(48.8%), 근위지골 및 근위지골간 관절부가 9례, 중수지절관절부가 7례 순으로 호발하였다. 방사선학적 소견상 연부조직에 방사선 비투과적인 균일한 연부조직 음영을 보이고 있었고 3명에서 피질골 미란을 보였다. 37명에서 종양은 단발성 병변이었으나 이 중 4명에서 다엽상으로 넓게 분포하였고, 1명에서 다발성 병변을 보였다. 변연부 절제술후 재발된 경우가 2명으로 재발율은 5.1%였다. 결론 : 수부에서 발생한 건초의 거대 세포종은 호발조건으로 50대, 여성, 인지, 굴곡건, 수지 원위부를 추정해 볼 수 있었으며, 불완전한 변연부 절제술을 시행하거나, 수술 후 재발한 경우, 다발성, 다엽상 소견을 보인 경우 재발이 잘 되므로 이 경우 광범위 절제술이 필요할 것으로 사료된다.

• 대한골관절종양학회지
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• 제16권1호
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• pp.21-26
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• 2010

목적: 발생 빈도가 드문 골연골종(증)에서 기인한 속발성 연골육종의 임상적, 방사선학적, 조직병리학적 소견과 더불어 수술적 치료의 결과를 알아보기 위하여 본 연구를 시행하였다. 대상 및 방법: 1992년 1월 1일부터 2004년 12월 31일까지 골연골종(증)에서 발생한 속발성 연골육종에 대해 수술적 치료를 받은 14명을 대상으로 환자들의 임상기록, 단순 방사선 및 전산화 단층촬영/자기공명영상, 병리조직 슬라이드를 후향적으로 조사하였다. 남성 9명, 여성 5명이었으며, 평균 나이는 34세(14-75세)였다. 평균 추시 기간은 54개월이었다. 결과: 모든 환자에서 소아기나 사춘기 전, 후부터 종괴를 가지고 있었으며, 방사선학적 소견은 종양의 표면이 불규칙하거나 경계가 불분명하거나, 분산된 무기질 침착 소견을 동반한 골파괴 음영 및 점상 석회화를 동반한 연부조직 종괴가 관찰되었다. 자기공명영상소견은 상기 방사선학적 소견을 반영하는 불균등신호 강도(inhomogeneous signal)의 불규칙한 경계를 지닌 종괴가 보이며, 연골모(cartilage cap)의 두께가 2예를 제외하고는 모두 1 cm 이상으로 두꺼웠다. 수술적 치료는 10명에서 광범위절제술, 3명에서 변연절제술 그리고 1명에서 절단술을 시행하였다. 결론: 골연골종(증)에서 드물기는 하나 속발성 연골육종이 발생할 수 있으므로, 임상적, 방사선학적 그리고 조직병리학적 소견을 종합적으로 이해하고 주의 깊게 추시 관찰 하여, 조기에 광범위 절제술을 시행할 경우 좋은 치료결과를 기대할 수 있을 것으로 사료된다.

• 대한골관절종양학회지
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• 제1권1호
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• pp.1-6
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• 1995

Giant cell tumors are primary bone tumors originating from non-osteoblastic connective tissue. The sites of involvement were commonly distal femur, proximal tibia, proximal humerus, distal radius and others (including os calcis, ilium and sacrum). Giant cell tumor located around knee joint has been difficult to treat because of local recurrence following curettage with or without bone graft. Although primary resections reduce recurrence of the lesion, the joint function will be markedly impaired. Marginal excision was very often complicated by a loss of joint integrity since all the giant cell tumors occupy juxtaarticular positions. Techniques involving physical adjuncts(high speed burr and electric cauterization) have been used in the hope of decreasing the rate of local recurrence and avoiding the morbidity of primary resection. A meticulous clinical, radiological and histological evaluation is needed to choose the correct treatment, keeping in mind the possibility of recurrence after each treatment modality.

• 대한골관절종양학회지
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• 제2권1호
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• pp.116-119
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• 1996

The solitary osteochondroma is a hamartoma of the skeleton which derives from an aberrant subperiosteal germ of the fertile cartilage. Osteochondromas, which are uncommon in the hand can occur at the distal end of the proximal and middle phalanx away from the epiphyseal plate region. We experienced a rare case of solitary osteochondroma arising from distal end of fifth proximal phalanx of hand, and limiting the active motion of proximal interphalangeal joint. The patient was treated by marginal excision and tumor showed characteristic microscopic findings of osteochondroma.

• 대한족부족관절학회지
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• 제19권3호
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• pp.132-135
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• 2015

We experienced a rare case of parosteal lipoma, which located on the periosteum of the foot 4th metatarsus. A 22-year-old woman visited the hospital with painful mass in her foot. Based on the assessment of plain radiographs, computed tomography scan, and magnetic resonance image, it was suspected as lipoma. Marginal excision was performed and parosteal lipoma was confirmed histologically. Any local recurrence and complications were not observed in 2 years after surgery.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제38권4호
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• pp.240-244
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• 2012

Myofibroblastic sarcoma is a rare tumor that mostly develops in the soft tissues of the head and neck. Within the oral cavity, a tongue lesion is the most common. A myofibroblastic sarcoma tends to recur locally instead of metastasizing. We encountered a myofibroblastic sarcoma of the mandible of a 9-year-old male and performed mass excision and additional marginal alveolectomy. So far, there is neither recurrence nor metastasis. We report this case because of the uncommon location of this tumor type and its surgical approach compared to other forms of sarcomas.

• 대한두경부종양학회지
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• 제24권2호
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• pp.197-199
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• 2008

Myoepithelioma is composed predominantly or exclusively of myoepithelial cells. It is most frequently located in parotid gland, the palate and the breasts. It accounts for less than l% of all salivary gland tumors. Surgical excision which accompany a marginal amount of uninvolved tissue is curative. We report a case of parotid gland myoepithelioma treated by surgery.