• Korean Journal of Biological Psychiatry
• /
• v.22 no.4
• /
• pp.149-154
• /
• 2015

Mood disorder is a common psychiatric illness with a high lifetime prevalence in the general population. Many prescribed antidepressants modulate monoamine neurotransmitters including serotonin, norepinephrine and dopamine. There has been greater focus on the major excitatory neurotransmitter in the human brain, glutamate, in the pathophysiology and treatment of major depressive disorder (MDD). Recently, ketamine, an N-methyl-D-aspartate receptor antagonist, has received attention and has been investigated for clinical trials and neurobiological studies. In this article, we will review the clinical evidence for glutamatergic dysfunction in MDD, the progress with ketamine as a rapidly acting antidepressant, and other N-methyl-D-aspartate receptor antagonist for treatment-resistant depression.

• Journal of Electrochemical Science and Technology
• /
• v.10 no.2
• /
• pp.231-243
• /
• 2019

The methanolic extracts of the leaves and stem of the plant Lepidagathis keralensis were evaluated for anticorrosion behavior against mild steel in 1M HCl. Corrosion inhibition studies were done by gravimetric method, electrochemical impedance spectroscopy and potentiodynamic polarization methods. Surface morphology of mild steel in the presence and absence of inhibitors were studied using SEM analysis. UV-Vis studies were also done to evaluate the mechanism of inhibition. Both the extracts showed good inhibition efficiency which increased with increase in concentration of the inhibitor and decreased with increase in temperature. The mechanism of inhibition was explained by adsorption which obeyed Langmuir adsorption isotherm. Thermodynamic calculations revealed a combination of both physisorption and chemisorption of the inhibitor on the surface of mild steel. The extracts behaved as mixed type inhibitors as determined by polarization studies. Quantum chemical studies on Phenoxyethene, one of the major components in the leaf extract of the plant was also carried out to support the experimental results.

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.44 no.4
• /
• pp.465-482
• /
• 2024

The global use of groundwater in coastal areas has increased. Events such as seawater intrusion (SWI) are expected to increase along with the acceleration of natural disasters owing to environmental changes such as climate change, resulting in large-scale damage worldwide. Current trends in the research of coastal groundwater and related natural disasters include testing and verifying technologies using major case studies from individual countries. We identified global research trends in coastal groundwater, related these trends to changing environments and climate, and confirmed the qualitative and quantitative growth of these studies. This study describes the theoretical background and techniques for coastal groundwater analysis and details regional-scale SWI indicators based on analytical and numerical studies. This review highlights recent technologies that consider uncertainty and promotes discussions on field data obtained using new technologies. Finally, the research findings and trends for a regional coastal aquifer in Korea are discussed to describe recent SWI approaches for groundwater resources.

• Journal of the Korean earth science society
• /
• v.41 no.4
• /
• pp.391-404
• /
• 2020

This study identified and examined earth science education department programs in Korea. Major courses provided by 11 universities and their course requirements were analyzed, and the main research results are as follows. First, many basic courses, other major requisite, and elective courses are provided in geology, astronomy, and atmospheric science. oceanography, geophysics, earth environmental science, and natural disaster and energy resources had fewer major requisite courses provided in addition to basic courses, and few elective courses were offered. Second, many courses in science education focused on earth science, while others focused on general science and there were few courses that covered education theory regarding the specific subject. Third, science course application requirements emphasized the understanding of science in general or of earth science specifically. From the above results, additional studies are proposed to reflect on the current state and supplement these programs.

• Journal of the Korean earth science society
• /
• v.44 no.2
• /
• pp.161-168
• /
• 2023

While numerous previous studies investigated the provenance and tectonic history of the Gyeongsang Supergroup, less are known about other Cretaceous strata in South Korea. This study presents preliminary results from petrographic analysis of the Cretaceous Icheonri Formation distributed in Gijang-gun, Busan. Based on the immature texture and composition of the Icheonri sediments, we interpret that they were derived from weakly denudated Cretaceous arc volcanoes developed along the eastern margin of the Asian continent, with limited weathering and transport. Additionally, the presence of chrome spinel grains in the sediments suggests the existence of ultramafic bodies exposed in their provenance. Further studies will advance our understanding of the tectonic developments in the southeastern Gyeongsang Basin, and facilitate a comprehensive correlation between the Icheonri Formation and the Gyeongsang Supergroup.

• Journal of Ginseng Research
• /
• v.45 no.3
• /
• pp.420-432
• /
• 2021

Background: Many ginsenosides have been shown to be efficacious for major depressive disorder (MDD), which is a highly recurrent disorder, through several preclinical studies. We aimed to review the literature assessing the antidepressant effects of ginsenosides on MDD animal models, to establish systematic scientific evidence in a rigorous manner. Methods: We performed a systematic review on the antidepressant effects of ginsenoside evaluated in in vivo studies. We searched for preclinical trials from inception to July 2019 in electronic databases such as Pubmed and Embase. In vivo studies examining the effect of a single ginsenoside on animal models of primary depression were included. Items of each study were evaluated by two independent reviewers. A meta-analysis was conducted to assess behavioral changes induced by ginsenoside Rg1, which was the most studied ginsenoside. Data were pooled using the random-effects models. Results: A total of 517 studies were identified, and 23 studies were included in the final analysis. They reported on many ginsenosides with different antidepressant effects and biological mechanisms of action. Of the 12 included articles assessing ginsenoside Rg1, pooled results of forced swimming test from 9 articles (mean difference (MD): 20.50, 95% CI: 16.13-24.87), and sucrose preference test from 11 articles (MD: 28.29, 95% CI: 22.90-33.69) showed significant differences compared with vehicle treatment. The risk of bias of each study was moderate, but there was significant heterogeneity across studies. Conclusion: These estimates suggest that ginsenosides, including ginsenoside Rg1, reduces symptoms of depression, modulates underlying mechanisms, and can be a promising antidepressant.

• Journal of the Korean Society for Library and Information Science
• /
• v.10
• /
• pp.71-120
• /
• 1983

In this study, a model curriculum for the Library and Information Science programs in Junior Colleges is presented by comparing those curricula of the Republic of Korea, the United States of America, England and Japan. In Korea, 80 credits are required for graduate of Junior College and 60 credits of that total credits are for major courses. At Toshokan Danki Daikagu in Japan, 73 credits are opened for the Department of Library Science and 87 credits for the Department of Library and Information Science respectively. In the United States of America, 30 credits for major courses out of 90 total credits are opened at Lansing Community College and 24 credits for major courses out of 60-64 credits at Mesa Community College distinctively. On the basis of the various analyses, the following principles are applied in designning the model curriculum; (1) Possibly 3 credits per subject are assigned, (2) Major credits for graduate are 60-64 credits including possible optional subjects, (3) 20 percents of those 60-64 credits shall be applied for electives, so that 72-78 credits are assigned for major, (4) In order to combine theory and practice, and to select practice areas as required major, the ratio between required and elective must be adjusted, (5) In order to avoid duplication of subject, adequate individuality must be provided, (6) The Information Science areas must be dealt with in Library Science since computer systems are being rapidly adopted in libraries and the education for resources of materials and foreign languages are also important for successful fulfillment of mediator's roles between materials and users. Therefore the following model curriculum is suggested; 31 credits in 11 subjects for required major, 46 credits in 18 subjects for electives in major, total 77 credits for 29 subjects are established, and it includes such areas as material organization, foreign languages, resources of materials, library management, information science, fundamental studies, services and practice.

• Journal of Trauma and Injury
• /
• v.35 no.2
• /
• pp.71-75
• /
• 2022

Trauma care is evolving throughout the world to meet the demand resulting from rapidly increasing rates of mortality and morbidity related to external injuries. The State Major Trauma Service was designated to Royal Perth Hospital in 2004 to provide comprehensive care for trauma patients in Western Australia (WA), which is the largest state by area in the country. The State Major Trauma Unit, which was established in 2008, functions as a level I center and admits over 1,000 major trauma patients per year, making it the second busiest trauma center in Australia. The importance of recording data related to trauma was identified by the trauma service in WA to inspire higher standards of patient care and injury prevention. In 1994, the service established a trauma registry, which has undergone significant changes over the last two decades. The current State Trauma Registry is linked to a statewide database called the Data Linkage System. The linked data are available for policy development, quality assurance, and research. This article discusses the evolution of the trauma service and the registry database in the WA health system. The State Trauma Registry has enormous potential to contribute to research and quality improvement studies along with its ability to link with other databases.

• Korean Journal of Child Studies
• /
• v.31 no.4
• /
• pp.111-124
• /
• 2010

The major purpose of this study was to explore mediating effects of narcissism between perceived popularity and aggression in adolescence. The subjects who participated in this study were 783 middle school students based in Busan. The results indicated that perceived popularity and narcissism were positively correlated to overt and relational aggression. The effects of perceived popularity on overt and relational aggression was perfectly mediated by narcissism. Athletic and fighting abilities were more important for boys' perceived popularity, but active involvement in social activity and appearance were more important for girls' perceived popularity. It was further observed that having a good sense of humour was the most important determinant of perceived popularity, irrespective of gender.

• Physical Therapy Korea
• /
• v.29 no.2
• /
• pp.131-139
• /
• 2022

Background: Shoulder impingement syndrome, a major cause of shoulder pain, involves weakness of the scapular retractor muscles. The major scapular retractor muscles are the middle trapezius and rhomboid major muscles; however, the latter is excluded in most studies. Objects: We aimed to measure the thickness of the middle trapezius and rhomboid major muscles using an ultrasonic diagnostic imaging system while performing four different shoulder retraction exercises and comparing the thicknesses and ratio of the thicknesses of these muscles. Methods: The thickness of the middle trapezius and rhomboid major muscles was measured in 24 healthy adults using ultrasound. Muscle thickness was measured three times in the Reference posture and four times while performing four different exercises that involved scapular retraction. The averages and standard deviations of the measured muscle thicknesses were obtained and compared. The ratio of muscle thickness and rate of changes in muscle thickness between the reference posture and the four exercises were compared. Results: For both, male (n = 10) and female (n = 14), there was a significant difference in the thickness of the middle trapezius muscle between the reference posture and the four exercises (p < 0.05) and in the thickness of the middle trapezius and rhomboid major muscles between male and female (p < 0.05); however, there was no significant difference in the ratio of the thicknesses of these muscles. Although a significant difference in the rate of change in muscle thickness during the four exercises was noted, there was no significant difference in the ratio of change in muscle thickness. Conclusion: This study demonstrates the ratio of the thicknesses of the middle trapezius and rhomboid major muscles and the rate of change in their thickness during exercises involving scapular retraction in healthy people in their 20s-30s.