• Korean Journal of Veterinary Service
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• v.19 no.1
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• pp.1-29
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• 1996

This study was conducted to elucidate the pathogenesis of Aujeszky's disease virus(ADV) by histopathologic examination. The first Korean ADV Isolate, which was isolated from piglets with clinical signs of Aujeszky's disease in Yangsan(YS) county, Kyungnam province, was inoculated into 32 days old piglets with a dose of $10^{5.9}$$TCID_{50}/ml$ through intranasal or intramuscular route. These piglets were sacrificed at intervals of every 24hrs for 8 days. The virulence of YS strain was determined by the observation of clinical signs, gross findings, and histopathologic changes in tissues. The virus recovery test was performed from brain, spleen, lung and tonsil in cell culture. The pathogenesis of YS strain was determined by the observation of histopathologlc lesions in CNS and neuronal tracts. The major clinical signs were fever, anorexia, dyspnea, constipation, tremor, ataxia, circling movement, hindleg paralysis and salivation. The clinical signs were more severe in piglets of the group inoculated intranasally than those of the intramuscularly inoculated gorup. Lymphocytopenia was detected on day 5 to day 6 postinoculation (PI). The ADV was recovered from the tissue homogenates of tonsil, lung, spleen and cerebrum in cell culture. The highest virus titer was detected from tonsil between day 6 and day 7 PI. Reddish sublobar consolidation foci were scattered in the apical and cardiac lobes of lung. Although yellowish necrotic foci were detected in tonsil and liver, hemorrhagic lesions were mainly observed in heart, kidney and lymph nodes. Histopathologically, degeneration and necrosis of nerve cells, nonsuppurative meningoe-ncephalitis, nodular gliosis and perivascular cuffings were observed in CNS. Multifocal fibronecrotic foci were observed in lung, liver, lymph nodes and spleen. The major pathologic changes were detected in the midbrain, pons and medulla oblongata. Eosinophilic intranuclear inclusion bodies were mainly observed in epithelia and /or macrophages of tonsil, liver, lung, spleen and submandibular lymph nodes, and neurons of brain, respectively. Observation of viral particles at various stages of replication were possible from the endothelial cells of the alveolar capillaries and tonsillar crypt epithelia by transmission electron microscope.

• Journal of agricultural medicine and community health
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• v.23 no.2
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• pp.243-250
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• 1998

This study was analyzed through the reports which published on the subject matter of Su Dong-Myun from 1994 to 1997 and the medical record of patient in Su-Dong Myun health subcenter. The result are as follow: 1. The number of population in Su-Dong Myun(study area) was 5,475 in 1994, 5,707 in 1995, 6,079 in 1996 and 6,253 in 1997. In composition rate of population, "65 and over" of age group only showed markedly increasing tendancy from 9.8% in l995 to 10.2% in 1997. However, the rest of all age group showed decreasing tendancy. 2. Annual utilization rate showed decreasing tendancy, such as 247 in 1994. 203 in 1995, 146 in 1996, and 140 in 1997 per 1000 population. But visiting time is increasing tendency, such as 3.1 in 1994, 2.8 in 1995. 2.4 in 1996 and 3.4 in 1997 per disease case. 3. Age specific annual utilization rate, all age showed decreasing tendancy in the age group of "0-14", "15-44" and "45-64", however showed increasing tendency in the age group of "65 and over" from 1994 to 1997. 4. The major disease were disease of Respiratory system. Gastrointestinal system. Musculoskeletal system and Connective tissue. Skin and Subcutaneous tissue and Circulatory system The disease of Musculoskeletal system and Connective tissue and Circulatory system are increasing.

• Journal of the Korean Society of Tobacco Science
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• v.33 no.1
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• pp.1-7
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• 2011

Major diseases of tobacco plants were surveyed throughout the Korea in 2011. Mosaic, bacterial wilt and hallow stalk were most severe during the harvest season on not only flue-cured tobacco plants but also burley tobacco plants. On flue-cured tobacco plants, mosaic caused by potato virus Y were more severe than those by tobacco mosaic virus or cucumber mosaic virus. The mosaic caused by potato virus Y was severe at Yeongwol and Chungju. On burley tobacco plants, mosaic were more severe at Jeongeup and Gochang than those at Chungnam and Jeonnam. A negative correlation between the mosaic incidence and the precipitation was recognized. On the other hand, there was a positive correlation between the incidence of hallow stalk incidence of flue-cured tobacco plants in harvesting stage and the precipitation during June was recognized significantly.

• Childhood Kidney Diseases
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• v.15 no.1
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• pp.1-13
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• 2011

Hypertension is a major risk factor of atherosclerosis which results in cardiovascular disease, and remains a major health problem worldwide. While children are more likely to have secondary hypertension, recent studies support the theory that the prevalence of essential hypertension in children and adolescents is increasing with the global epidemic of childhood obesity, and close attention is needed. Evaluation of hypertension in the pediatric age group should be guided by the age at presentation, and renal diseases must be considered in every child with hypertension, because of the prevalence of renovascular and renal parenchymal disorders as the etiology in any age group. The majority of children with chronic kidney disease are hypertensive, and many have associated end organ damage. Thus, once hypertension has been confirmed, end organ care as well as pharmacologic therapy must be continued. In renovascular hypertension, as cure could be gained with surgical/endovascular intervention, accurate diagnosis is important and it is recommended that every suspected child should undergo angiography.

• The Plant Pathology Journal
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• v.26 no.3
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• pp.260-263
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• 2010

Scald, caused by Rhynchosporium secalis has been the major yield-reducing factor for barley production during the last decade. In this study, pathogenic groups of R. secalis were identified to obtain a global picture of the assembly of isolates involved in Syrian populations which is essential for the development of scald-resistant barley cultivars. To identify a number of pathogenic groups, 49 isolates collected over ten years from major barley growing areas in Syria were evaluated on five differential barley genotypes. Genotypes presented a continuous range of response from highly susceptible to moderately resistant, but none were immune to the disease. A cluster analysis placed isolates in six distinct differential pathogenic groups. Mean disease rating of 39.24% was the separation point between avirulent and virulent reactions. Isolate Rs46 exhibited distinct differential virulence patterns associated with high frequency across all genotypes. Hence, the data presented here provides crucial information for future selection of isolates to develop durable barley scald resistance.

• Research in Plant Disease
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• v.7 no.1
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• pp.56-59
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• 2001

Stem rot of cacti was found at major cultivating areas including Koyang, Ansung and Eumsung of Korea in 2000. Bipolaris cactivora was consistently isolated from the lesions. The disease occurred on different species of cactus including Cereus peruvianus, C. neopithahaja f. monstruo년, C. tetragonus, Chamaeceresu silestrii, Ch. silvestrii, f. variegata, Gymnocalcium mihanovichii var. friedrichii. G. denudatum var. pentacantha, Hylocereus trigonus and Isolatocereus dumortier. Major symptoms on the cactus species except H. trigohus were almost identical. A rapid rot of the upper portion of the catus stem appeared, and became blackened and somewhat dry. On H. trigonus, the symptom was initially light yellow, water-soaked lesion, turned into light brown and dried to death. According to pathogenicity test, 10 out of 16 cactus species and varieties tested produced identical symptoms as found in the field. However, the fungi did not show pathogenicity to Notocactus scopa, Echinocactus grusonii, Eriocactus leninghausii, Lobivia nealeana, Mammillaria elongata var. intertexta.

• Journal of Chest Surgery
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• v.50 no.2
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• pp.105-109
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• 2017

Coronary arterial involvement in Takayasu arteritis (TA) is not uncommon. Herein, we describe a case of TA with celiac trunk and superior mesenteric artery occlusion combined with coronary artery disease. Bilateral huge internal thoracic arteries (ITAs) and the inferior mesenteric artery provided the major visceral collateral circulation. After percutaneous intervention to the right coronary artery, off-pump coronary artery bypass grafting for the left coronary territory was done using a right ITA graft and its large side branch because of its relatively minor contribution to the visceral collateral circulation.

• Toxicological Research
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• v.32 no.1
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• pp.65-72
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• 2016

Man-made cadmium (Cd) emissions can be transported between environmental matrices and the food chain. Food is the primary source of Cd exposure among general population as a consequence of the bioconcentration of Cd from soil. Chronic Cd exposure has been reported to be associated with chronic kidney disease, osteoporosis, diabetes, cardiovascular disease and cancer. The Joint FAO/WHO Expert Committee on Food Additives (JECFA) established the safe level of Cd intake as provisional tolerable monthly intake (PTMI) of $25{\mu}g/kg\;bw$ in 2010. The major food groups that contribute to the most Cd exposure are rice and grains, shellfish and sea food, meat including edible offal, and vegetables. A number of studies reported the high Cd contaminated levels in foods from polluted areas in Thailand. The results are of high concern since the contaminations occur in foods that are major Cd contributors. Thus, in this review, the current situations of Cd contaminated foods in polluted areas of Thailand are summarized. In addition, the Cd intakes from selected scenarios are estimated to assess the potential health risk to consumers and the suggestions are also included.

• Journal of Navigation and Port Research
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• v.46 no.2
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• pp.145-157
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• 2022

Due to the global epidemic of infectious diseases, it has become important for all industries to respond to the risk of infectious diseases. Ports in each country are also responding to the risk of infectious diseases, but the occurrence of infectious diseases in ports of various countries is causing a lot of damage to the logistics of ports. Korea is in the same situation, and cases of infectious diseases in ports are steadily being announced. Therefore, this paper conducted semi-quantitative Bow-Tie risk assessment by substituting measures to cope with infectious disease risks in Korean ports into actual cases of port infectious diseases in Korea, deriving improvements and suggesting directions. As a result, it was concluded that it was necessary to standardize some of the countermeasures against infectious diseases and develop more countermeasures.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.23 no.1
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• pp.12-16
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• 2023

Patients with inborn metabolic disorder (IMD) show multisystemic manifestations. Heterogenous renal manifestations can develop in IMD patients as well. In this review, the major renal manifestations of IMD and their representative IMDs are described. The major renal manifestations include Fanconi syndrome, renal tubular acidosis, nephrolithiasis, renal cysts and glomerulopathy, and diverse types of IMDs such as carbohydrate metabolism disorders, lysosomal disorders, organic acidemias, mitochondrial disorders, purine and pyrimidine disorders present renal manifestations. Therefore, general and regular renal function evaluation is recommended in addition to specific investigation according to IMD phenotypes.