• The KIPS Transactions:PartC
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• v.11C no.7 s.96
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• pp.1033-1042
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• 2004

According to the arbitration mechanism among the peers in the network, the P2P networking environments can be classified into hybrid P2P networking environments and pure P2P networking environments. In hybrid P2P networking environments, each peer gets continual services from the servers that arc operational most of the time, and so, network isolation does not occur because every peer can always keep connection to the server. In pure P2P networking environments, however, every peer directly connects to another peer without server intervention, and so, network isolation can occur when the per mediating the connection is terminated. In this paper, we propose a scheme for each peer to keep connection information of other peers by maintaining IDs of its neighbor peers, to reconnect to another peers when the mediating peer fails to work. and, for efficiency. to balance the number of connections that should be maintained by each peer. With our mechanism, each pier in the network can continuously maintain connection to the network and get seamless services from other peers. Through the simulation, we ascer-tained that network isolation does not occur in the pure P2P network adopting our mechanism and that our mechanism distributes and balances the connections that are maintained by each peer. We also analyzed the total network traffic and the mean number of hops for the connections made by each peer according to the recommended number of connections that is established at system setup time.

• Korean Journal of Ecology and Environment
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• v.39 no.4 s.118
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• pp.508-515
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• 2006

This study was conducted from July to December 2004, in order to find measures to improve the water quality and the function of pond ecosystems which are often negatively affected by phytoplankton and suspended particle matters. Most of the time, the management of ponds in Korea does not consider the ecological concepts such as self-purification and nutrient recycling. Instead, conventional methods depend on other factors such as fish farming and the function of fountains and waterfalls. Sustainability of pond ecosystems must be studied with the highest emphasis given to water quality. Water discharges of inflow and outflow as well as balance adjustment for different factors must be thoroughly studied. There is a great need for studies on sustainability because it can be realized through the horizontal or vertical balances of an ecosystem. Our current research offers useful information to the academia and public on maintaining sustainability in terms of structure and function of the pond.

• Korean Journal of Applied Biomechanics
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• v.16 no.1
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• pp.55-63
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• 2006

The purpose of this study is to prove the kinematical characteristics of Deff motion, the high bar performance, in terms of flying phases so that we can provide basic sources for improving gymnastic performance. To do this, we selected and analyzed the performance of two athletes who did Deff motion in the high bar competition of male artistic gymnastic in the 22nd Universiade 2003 Daegu. We drew the conclusions from the kinematical factors that were came out through analyzing three-dimensional cinematography of the athletes' movements, by using a high speed video camera. To make a successful performance, a performer releases the bar at a height of a high bar vertically and at a height of 82cm horizontally, and the flying performance should be made without moving forward, as maintaining the proper balance, in order to rise over 118cm high during the flying phase. When the performer is releasing the bar, an increase of the vertical speed in the center of the body and extension of a knee joint and a hip joint contribute to increasing a flying height. And when the moving body is twisted, leaning to left side is caused by the winding movement of a knee joint, which causes an unstable bar grasp. To grasp the bar stably, just before releasing the performer should gain propulsive force from twisting rotation through increasing the speed of shoulder rotation. And before the peak point, the performer should make sure of a body rotation distance over $164^{\circ}$ so that he or she can do an aerial rotary performance smoothly. When grasping the high bar, the center of the body should be above the bar and the angle of shoulder rotation should be maintained close to $540^{\circ}$ simultaneously. he high point performance(S1) has more speed on an ascending phase and less speed on a descending phase than the low point performance (S2). At the peak point, both the rotation angle of the body and that of the shoulder in high point performance are big as well. In conclusion, it is shown that a performer can make a jump toward the high bar easily with the body straight because the performer can hold the upper part of the body erect early in a descending phase.

• KSBB Journal
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• v.28 no.1
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• pp.1-6
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• 2013

Curcumin has diverse anticancer activities that lead to tumor growth inhibition of cancer cells and induction of apoptosis. Curcumin is involved in the regulation of multiple genes via transcription factors including NF-${\kappa}B$, STATs, AP1, and SP. Notch signaling plays critical roles in maintaining the balance between cell proliferation, differentiation and apoptosis, and thereby may contribute to the development of various cancers involving breast cancer. This study was to investigate the effects of curcumin on Notch1 gene expression and to explore the underlying mechanism. Here, we found that curcumin decreased the levels of Notch1 mRNA and protein in MDA-MB-231 human breast cancer cells, along with the downregulation of Sp family genes (Sp1, Sp2, Sp3, and Sp4). The repressive effect of curcumin on Notch1 gene transcription was confirmed by performing Notch1 promoter-driven reporter assay and three Sp-binding sites were identified on Notch1 promoter that may act as curcumin-respose elements. Moreover, treatment with mitramycin A, a specific Sp inhibitor, decreased the levels of Notch1 mRNA and protein in human breast cancer cells. Taken together, our results indicate that Notch1 gene expression is downregulated by curcumin, at least in part, through the suppression of Sp family, which may lead to apoptosis in human breast cancer cells.

• Korean Journal of Community Nutrition
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• v.24 no.6
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• pp.525-534
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• 2019

Objectives: Reduced glucose utilization in the main parts of the brain involved in memory is a major cause of Alzheimer's disease, in which ketone bodies are used as the only and effective alternative energy source of glucose. This study examined the effects of a low-carbohydrate and high-fat (LCHF) diet supplemented with a ketogenic nutrition drink on cognitive function and physical activity in the elderly at high risk for dementia. Methods: The participants of this study were 28 healthy elderly aged 60-91 years showing a high risk factor of dementia or whose Korean Mini-Mental State Examination (K-MMSE) score was less than 24 points. Over 3 weeks, the case group was given an LCHF diet with nutrition drinks consisting of a ketone/non-ketone ratio of 1.73:1, whereas the control group consumed well-balanced nutrition drinks while maintaining a normal diet. After 3 weeks, K-MMSE, body composition, urine ketone bodies, and physical ability were all evaluated. Results: Urine ketone bodies of all case group subjects were positive, and K-MMSE score was significantly elevated in the case group only (p=0.021). Weight and BMI were elevated in the control group only (p<0.05). Grip strength was elevated in all subjects (p<0.01), and measurements of gait speed and one leg balance were improved only in the case group (p<0.05). Conclusions: We suggest that adherence to the LCHF diet supplemented with a ketogenic drink could possibly influence cognitive and physical function in the elderly with a high risk factor for dementia. Further, we confirmed the applicability of this dietary intervention in the elderly based on its lack of any side effects or changes in nutritional status.

• Journal of Korea Port Economic Association
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• v.34 no.2
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• pp.17-30
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• 2018

The regional industry promotion system, which seeks to link the characteristics and resources of the region to its core strategic industry, is spreading the industrial resources in the form of an organic network. The Seosan-Daesan Port is the only port in the Chungcheong provinces that is equipped with international passenger dock and terminal, and it will soon have a ferry service operating to the Longyan port in Rongcheng, China in 2018. The study focuses on effects of the first international ferry operation in the provinces that are being realized with the aim of developing the regional industry. The study also analyzes the ripple effects on the tourism and port industries in the provinces by tapping into the 2013 regional inter-industry table. The analysis shows that the scheduled ferry operation will generate 47,815 million won in production and 23,423 million won in added value for the region's tourism industry. It will also generate total revenue of 12,567 million won for the port industry driven by the locally handled freight containers and the added value. Currently, the Korea-China ferry operation in other regions exhibits greater dependence on the cargo than the passengers. Thus, for the international ferry operation to and from Seosan, generating maximum employment in tourism from the passengers of the international ferry operation will require strategic marketing to attract tourists. At the same time, a steady supply of cargo needs to be sustained by maintaining a balance between import and export cargoes. Furthermore, greater efforts should be made to create more sea routes than other regions or to increase voyages for the purpose of generating more added value.

• Korean Journal of Remote Sensing
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• v.34 no.6_1
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• pp.1025-1032
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• 2018

Snow Cover is a form of precipitation that is defined by snow on the surface and is the single largest component of the cryosphere that plays an important role in maintaining the energy balance between the earth's surface and the atmosphere. It affects the regulation of the Earth's surface temperature. However, since snow cover is mainly distributed in area where human access is difficult, snow cover detection using satellites is actively performed, and snow cover detection in forest area is an important process as well as distinguishing between cloud and snow. In this study, we applied the Normalized Difference Snow Index (NDSI) and the Normalized Difference Vegetation Index (NDVI) to the geostationary satellites for the snow detection of forest area in existing polar orbit satellites. On the rest of the forest area, the snow cover detection using $R_{1.61{\mu}m}$ anomaly technique and NDSI was performed. As a result of the indirect validation using the snow cover data and the Visible Infrared Imaging Radiometer (VIIRS) snow cover data, the probability of detection (POD) was 99.95 % and the False Alarm Ratio (FAR) was 16.63 %. We also performed qualitative validation using the Himawari-8 Advanced Himawari Imager (AHI) RGB image. The result showed that the areas detected by the VIIRS Snow Cover miss pixel are mixed with the area detected by the research false pixel.

• Korean Journal of Clinical Laboratory Science
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• v.53 no.3
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• pp.249-256
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• 2021

Asthma is a chronic inflammatory airway disease. There are many factors including genetic and environmental factors that influence asthma. The mitogen-activated protein kinase (MAPK) pathway is involved in maintaining the T helper cells 1 and 2 (Th1/Th2) balance and plays an important role in the development of asthma. In this study, the correlation between the NDFIP2 gene that regulates the MAPK pathway and asthma was analyzed. The genetic polymorphism of the NDFIP2 gene was analyzed between 193 asthma patients and 3,228 healthy controls in Korea. As a result, 4 single nucleotide polymorphisms (SNPs) showed a significant correlation (P<0.05) and high relative risk with asthma. Among them, rs2783122 of NDFIP2 showed a statistically significant association with asthma (P-value=9.76×10^-6, odds ratio (OR)=1.67, 95% confidence interval (CI)=1.33~2.10). In the SNP imputation on the NDFIP2, 16 SNPs were discovered, and all of them showed significant correlation with asthma and high odds ratio. The genotype-based mRNA expression analysis revealed that the group of minor alleles of rs1408049 showed increased mRNA expression. Increased NDFIP2 expression causes the activation of the MAPK pathway, and this may influence the development of asthma. In conclusion, the polymorphisms of NDFIP2 are associated with asthma development and this can provide the basis for new guidelines for the management of asthma in the Korean population.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.12
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• pp.417-425
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• 2020

Recently, the development of weapons systems in conjunction with the Fourth Industrial Revolution has increased the number of weapon systems that integrate individual commercial systems by actively incorporating the superior fields of private commercial technologies. In the case of such commercial product-based weapons systems, however, the development of ILS elements across all areas, such as technical manual, military field maintenance support equipment, interactive electronic technical manual (IETM), and Computer Based Training (CBT) development, and weapons system Reliability, Availability, Maintainability(RAM) target values, and logistics support analysis (LSA) was requested to expand the level of development by developers. The commercial product-based System Integration (SI) weapon system will be able to complete the comprehensive military balance for complementing and effective maintenance of the military and developers only when the ILS development, which is limited to the essential elements of the required group, Request For Proposal (RFP) and Post-Logistics Support (PLS) directions were applied in the framework of outsourcing maintenance implementation. As a result, by checking the operation status of current weapons systems, the logistics support of commercial product-based weapon systems selected outsourcing as the basic policy that is decided based on the development requirements, focusing on maintaining operation through a rational decision-making process, and presented a plan for applying the development plan to the RFP for the determined core elements and PLS.

• Korean journal of applied entomology
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• v.61 no.1
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• pp.229-238
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• 2022

Animal pollination is an important ecosystem service provided mostly by diverse insect groups such as bees and hover flies. Maintaining agricultural productivity and securing the nutritional balance are closely tied to human wellbeing. This study aimed to estimate the pollination dependent food production in Korean agricultural system. Crop production data were obtained from Korean statistical information service (KOSIS) data of 2015. By implementing pollination dependency, crop production and market price, contribution of insect pollination to crop production increase were estimated from total 71 crops including 12 cereals, 19 fruits, 18 field vegetables, 13 greenhouse vegetables and 9 specialty crops. Mean pollination dependency of all crops were 29.2% and it was higher on fruits, specialty crops and greenhouse vegetables as well, but low (7.5%) in cereal crops. Pollination dependent (PD) production was estimated as 17.8% of total agricultural crop production with the economic value of 6,850 (6,508-7,193) billion won. Especially, PD production of greenhouse vegetables accounted 49.2% followed by fruits of 42.9%. Even specialty crop also showed higher PD production (35.9%). It was obvious that pollination is the vital service for agricultural production as well as nutritional security in Korea. Further protection and enhancing the pollination service were discussed with integrated pollinator-pest management (IPPM) strategies.