• KCI Concrete Journal
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• v.12 no.2
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• pp.85-93
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• 2000

Potentially significant mechanical improvements in tension can be achieved by the incorporation of randomly distributed, short discrete fibers in concrete. The improvements due to the incorporation fibers significantly influence the composite stress - strain ($\sigma$-$\varepsilon$) characteristics. In general incorporating fibers in a plain concrete has relatively small effect on its precracking behavior. It, however, alters its post-cracking behavior quite significantly, resulting in greatly improved ductility, crack controls, and energy absorption capacity (or toughness). Therefore, a thorough understanding the complete tensile stress - strain ($\sigma$-$\varepsilon$) response of fiber reinforced concrete is necessary for proper analysis while using structural components made with fiber reinforced concrete. Direct tensile stress applied to a specimen is in principle the simplest configuration for determining the tensile response of concrete. However, problems associated with testing brittle materials in tension include (i) the problem related to gripping of the specimen and (ii) the problem of ensuring centric loading. Routinely, indirect tension tests for plain concrete, flexural and split-cylinder tests, have been used as simpler alternatives to direct uniaxial tension test. They are assumed to suitable for fiber reinforced concrete since typically such composites comprise 98% by volume of plain concrete. Clearly since the post-cracking characteristics are significantly influenced by the reinforcing parameters and interface characteristics, it would be fundamentally incorrect to use indirect tensile tests for determining the tensile properties of fiber reinforced concrete. The present investigation represents a systematic look at the failure and toughening mechanisms and macroscopic stress - strain ($\sigma$-$\varepsilon$) characteristics of fiber reinforced concrete in the uniaxial tension test. Results from an experimental parametric study involving used fiber quantity, type, and mechanical properties in the uniaxial tension test are presented and discussed.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.36 no.10
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• pp.1283-1288
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• 2012

A process heat exchanger (PHE) in a nuclear hydrogen system is a key component for transferring the considerable heat generated in a very high temperature reactor (VHTR) to a chemical reaction that yields a large quantity of hydrogen. A performance test on a medium-scale PHE prototype made of $Hastelloy^{(R)}$-X is scheduled in a small-scale gas loop at the Korea Atomic Energy Research Institute. In this study, as a preliminary study before carrying out the performance test in the gas loop, high-temperature structural analysis modeling and macroscopic thermal and structural analysis of the medium-scale PHE prototype by imposing the established displacement boundary constraints were carried out under the gas loop test condition. The results obtained in this study will be compared with the performance test results of the medium-scale PHE prototype in the gas loop.

• Journal of Pharmacopuncture
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• v.18 no.3
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• pp.42-48
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• 2015

Objectives: The aim of the study is to investigate both the single-dose intramuscular injection toxicity and the approximate lethal dose of water-soluble Carthami-flos and Cervi cornu parvum pharmacopuncture (WCFC) in male and female Sprague-Dawley (SD) rats. Methods: The study was conducted at Biotoxtech Co. according to the Good Laboratory Practice (GLP) regulation and the toxicity test guidelines of the Ministry of Food and Drug Safety (MFDS) after approval of the Institutional Animal Care and Use Committee. Dosages for the control, high dose, middle dose and low dose groups were 0.5 mL/animal of saline and 0.5, 0.25 and 0.125 mL/animal of WCFC, respectively. WCFC was injected into the muscle of the left femoral region by using a disposable syringe (1 mL, 26 gauge). The general symptoms and mortality were observed 30 minutes, 1, 2, 4, and 6 hours after the first injection and then daily for 14 days after the injection. The body weights of the SD rats were measured on the day of the injection (before injection) and on the third, seventh, and fourteenth days after the injection. Serum biochemical and hematologic tests, necropsy examinations, and histopathologic examinations at the injection site were performed after the observation period. Results: No deaths, abnormal clinical symptoms, or significant weight changes were observed in either male or female SD rats in the control or the test (0.125, 0.25, and 0.5 mL/animal) groups during the observation period. No significant differences in hematology and serum biochemistry and no macroscopic abnormalities at necropsy were found. No abnormal reactions at injection sites were noted on the topical tolerance tests. Conclusion: The results of this single-dose toxicity study show that WCFC is safe, its lethal doses in male and female SD rats being estimated to be higher than 0.5 mL/animal.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.35 no.2
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• pp.191-200
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• 2011

A PHE (Process Heat Exchanger) is a key component of nuclear hydrogen system for massive production of hydrogen; the PHE transfers the very high temperature heat ($950^{\circ}C$) generated from the VHTR (Very High Temperature Reactor) to a chemical reaction. The Korea Atomic Energy Research Institute developed a small-scale gas loop for testing the performance of VHTR components and manufactured a modified PHE prototype for carrying out the testing in the gas loop. In this study, as a part of the evaluation of the high-temperature structural integrity of the modified PHE prototype which is scheduled to test in the gas loop, we carried out high-temperature structural analysis modeling, macroscopic thermal and structural analysis of the PHE prototype under the gas loop test conditions as a precedent study before carrying out the performance test in the gas loop. The results obtained in this study will be used to design the performance test setup for the modified PHE prototype.

• Geomechanics and Engineering
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• v.23 no.2
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• pp.139-149
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• 2020

Piles are widely used in structural foundations of engineering projects. However, the deformation of the soil around the pile caused by driving process has an adverse effect on adjacent existing underground buildings. Many previous studies have addressed related problems in sand and saturated clay. Nevertheless, the failure mechanism of pile driving in unsaturated soil remains scarcely reported, and this issue needs to be studied. In this study, a modeling test system based on particle image velocimetry (PIV) was developed for studying deformation characteristics of pile driving in unsaturated silt with different water contents. Meanwhile, a series of direct shear tests and soil-water characteristic curve (SWCC) tests also were conducted. The test results show that the displacement field shows an apparent squeezing effect under the pile end. The installation pressure and displacement field characteristics are sensitive to the water content. The installation pressure is the largest and the total displacement field is the smallest, for specimens compacted at water content of 11.5%. These observations can be reasonably interpreted according to the relevant unsaturated silt theory derived from SWCC tests and direct shear tests. The variation characteristics of the soil displacement field reflect the macroscopic mechanical properties of the soil around the pile.

• Journal of Environmental Health Sciences
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• v.41 no.6
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• pp.405-411
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• 2015

Objectives: The purpose of this study is to evaluate the optimum conditions for oral mucosal irritation testing using the buccal pouch of hamsters. Methods: Test materials were applied to the buccal pouch of seven-week old male Syrian hamsters (SLC, Japan) four times at one-hour intervals and macroscopic changes were examined at 24 hours after final treatment. After sacrifice, the buccal pouches were removed and prepared for histopathological evaluation. In order to set the exposure time, we performed exposure tests of 5, 12, 18 and 23 minutes using sodium lauryl sulfate (SLS) 1% and set the treatment volume from the test results at 2, 3, or 4 ml treatment using SLS 1%, Triton X-100 1% and ethanol. After setting the experimental conditions, seven groups of materials [sodium lauryl sulfate (SLS) (1%), Triton X-100 (1%), hydrogen peroxide (3%), ethanol (100%), chlorhexidine (0.2%, 2%), phosphate buffer saline (PBS)] were assessed. Results: Experimental conditions of material exposure time were fixed as 18 minutes from the exposure tests of 5, 12, 18 or 23 min using sodium lauryl sulfate (SLS) 1%. Treated volume was set as 4 ml per each pouch from the test results of 2, 3, or 4 ml treatments using SLS 1%, Triton X-100 1% and ethanol. The results in terms of irritation degree were in the order of sodium lauryl sulfate (SLS) (1%) > Triton X-100 (1%) ${\fallingdotseq}$ hydrogen peroxide (3%) > ethanol (100%) ${\fallingdotseq}$ chlorhexidine (0.2%, 2%) > phosphate buffer saline (PBS). Conclusion: From this study, suitable conditions for hamster mucosal irritation testing were suggested and this method was verified through materials commonly used on oral mucosal membranes.

• Korean Journal of Veterinary Research
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• v.57 no.4
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• pp.227-233
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• 2017

To reduce swine production costs, a slaughter check system has been developed in countries with an advanced swine industry. Evaluation of lung lesions in carcasses is a critical part of the slaughter check system. This study was performed to collect background information for use in developing a slaughter check system in Korea. Lung tissues and their gross images were collected from slaughterhouses in Gyeonggi-do, Korea. Scoring of the gross lung lesions was performed on the lung images. Histopathologic examination was conducted to classify the pulmonary lesions as bronchopneumonia or interstitial pneumonia. Scores of the gross lung lesions were significantly different between bronchopneumonia and interstitial pneumonia groups (p < 0.001). A 90% confidence interval of gross lung lesion scores was established for the bronchopneumonia group, and the lesion scoring had a sensitivity of 100% and specificity of 77.3%. The gross lung lesion scoring test was subjected to a diagnostic distinction evaluation by examining the receiver operating characteristic curve and was appraised as having good discrimination for bronchopneumonia. Establishment of a gross lung lesion scoring test for the diagnosis of bronchopneumonia could be valuable as a screening test of macroscopic bronchopneumonia in swine slaughter check system.

• The Journal of Korean Society of Virology
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• v.28 no.4
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• pp.377-382
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• 1998

Hemorrhagic fever with renal syndrome (HFRS), scrub typhus, murine typhus and leptospirosis have been the principal acute febrile diseases in Korea. To evaluate the seroepidemiologic patterns of acute febrile illness, sera collected from 2,423 patients in 1996 were examined for antibodies against Hantaan virus, Orientia tsutsugamushi, Rickettsia typhi, and Borrelia burgdorferi by indirect immunofluorescent antibody technique (IFA) and macroscopic agglutination test for Leptospira interogans. Seropositive cases against Otsutsugamushi, Rickettsia typhi, Leptospira interogans and Hantaan virus were 192 (7.9%), 193 (8.0%), 12 (0.5%) and 324 (13.4%), respectively. Male was more affected in HFRS and murine typhus contrasting to scrub typhus and leptospirosis in female. Most positive cases occurred during October and November for scrub typhus, and during November and December for HFRS. These results showed similar patterns with previous epidemical data for recent couple of years, and possibly implied no significant changes occurred in ecologic situations for acute febrile diseases in Korea.

• Proceedings of the Korean Vacuum Society Conference
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• 2013.02a
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• pp.598-598
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• 2013

The short lifetime of Proton Exchange Membrane Fuel Cell (PEMFC) is the one of the main problems to be solved for commercializing. Especially, the weak adhesion between metal nanoparticles and supports deteriorate the performances of nanocatalysts, therefore, it is considered to be a major failure mechanism. Using force-distance spectroscopy of atomic force microscopy (AFM), we characterized the adhesion between Pt nanoparticles and carbon supports that is crucially related to the durability for membrane fuel cell (MFC) electrode. In our study, force distance curves measured with Pt coated AFM cantilever, mimicking the behavior of corresponding nanoparticles on carbon supports, leads to the adhesion between metal nanoparticles and carbon supports. We found that theadhesion between Pt and HNO3-treated carbon is enhanced by a factor of 4, compared to Pt and bare carbon support, that is consistent with the macroscopic durability test of PEMFC. The higher adhesion between Pt and HNO3-treated carbon can be explained in light of the stronger chemical interaction by C/O functional groups.

• Interaction and multiscale mechanics
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• v.4 no.3
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• pp.187-206
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• 2011

Accurate estimations of pre-failure deformations and post-failure responses of geostructures require that the simulation tool possesses at least three main ingredients: 1) a constitutive model that is able to describe the macroscopic stress-strain-strength behavior of soils subjected to complex stress/strain paths over a wide range of confining pressures and densities, 2) an embedded length scale that accounts for the intricate physical phenomena that occur at the grain size scale in the soil, and 3) a computational platform that allows the analysis to be carried out beyond the development of an initially "contained" failure zone in the soil. In this paper, a two-scale micropolar plasticity model will be used to incorporate all these ingredients. The model is implemented in a finite element platform that is based on the mechanics of micropolar continua. Appropriate finite elements are developed to couple displacement, micro-rotations, and pore-water pressure in form of $u_n-{\phi}_m$ and $u_n-p_m-{\phi}_m$ (n > m) elements for analysis of dry and saturated soils. Performance of the model is assessed in a biaxial compression test on a slightly heterogeneous specimen of sand. The role of micropolar component of the model on capturing the post-failure response of the soil is demonstrated.