• Journal of Communications and Networks
• /
• v.15 no.5
• /
• pp.469-475
• /
• 2013

In this paper, we propose an efficient interference management technique which controls the number of resource blocks (or subcarriers) shared with other cells based on statistical interference levels among cells. The proposed technique tries to maximize average throughput of a femto cell user under a constraint on non-real time control of a femto cell network while guaranteeing a target throughput value of a macro cell user. In our proposed scheme, femto cells opportunistically use resource blocks allocated to other cells if the required average user throughput is not attained with the primarily allocated resource blocks. The proposed method is similar to the underlay approach in cognitive radio systems, but resource block sharing among cells is statistically controlled. For the statistical control, a femto cell sever constructs a table storing average mutual interference among cells and periodically updates the table. This statistical approach fully satisfies the constraint of non-real time control for femto cell networks. Our simulation results show that the proposed scheme achieves higher average femto user throughput than conventional frequency reuse schemes for time varying number of users.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.17 no.12
• /
• pp.2806-2811
• /
• 2013

New technologies such as multi-antenna and small cell were proposed as key technology for the next generation mobile system to cope with the explosively increasing mobile data traffic. In particular, heterogeneous mobile communication network which can improve spatial reuse factor by exploiting macro and small cells simultaneously is attracting attention. However, the heterogeneous network has a problem that the utilization of small cells becomes low because the transmit power of macro base stations is much higher than that of small base stations and then the probability that mobile stations are attached to the macro base stations becomes high. This problem is dominant in uplink. The concept of cell range expansion bias to mitigate the problem was proposed by 3GPP and the corresponding standardization is in progress. In this paper, we analyze the downlink performance of the heterogeneous mobile communication network based on a system level simulator with the cell range expansion bias in terms of average cell spectral efficiency.

• Journal of Periodontal and Implant Science
• /
• v.35 no.4
• /
• pp.1097-1108
• /
• 2005

The present study was to determine the influence of micro-macro biphasic calcium phosphate(MBCP) on proliferation and differentiation of human marrow-derived mesenchymal stem cells. Primary stem cells were cultured from bone marrow and 3-4 passaged cells were used. This study tested the proliferative effects by cell counting. Collagen sythensis, alkaline phosphatase activity, expression of osteocalcin and bone sialoprotein by Western blot analysis were evaluated. The cellular proliferation of ASC was not influenced by MBCP. Collagen synthesis of ASC cultured on MBCP significantly increased at 5th and 7th days(p<0.05). The ALP activity in ASC cultured on MBCP significantly increased at 5th and 7th days(p<0.05). The expression of OC and BSP incresaed in ASC cultured on MBCP. These results suggest that MBCP may stimulates the osteoblastic activity of ASC.

• Journal of the Korean Society for Aeronautical & Space Sciences
• /
• v.35 no.5
• /
• pp.390-396
• /
• 2007

In the present study, we have developed a flapping wing using a smart material to mimic the nature's flyers, birds. The wing consists of composite frames, a flexible PVC film and a surface actuator, and the main wing motions are flapping, twisting and camber motions. To change the camber, a Macro-Fiber Composite(MFC) is used as the surface actuator, and it's structural response is analyzed by the use of piezoelectric-thermal analogy. To measure the lift and thrust simultaneously, a test stand consisting of two load cells is manufactured. Some aerodynamic tests are performed for the wing in a subsonic wind tunnel to evaluate the dynamic characteristics. Experimental results show that the main lift is mostly affected by the forward velocity and the pitch angle, but the thrust is mostly affected by the flapping frequency. The effect of the camber generated by the MFC actuator can produce the sufficient lift increment of up to 24.4% in static condition and 20.8% in dynamic condition.

• Journal of the Institute of Convergence Signal Processing
• /
• v.17 no.1
• /
• pp.1-9
• /
• 2016

In this paper, for the improvement of quality of service(QoS) performance of heterogeneous networks, multi-cell scheduling is proposed. In order to implement the proposed algorithm, for the recognition of the impact on the throughput performance of users, macro-pico-cells that form distributed architecture were proposed. In operating heterogeneous networks, considering the centralized structure, a macro-RRH(Remote Radio Head) deployment scenario was proposed. For interference mitigation of the proposed system, by applying the optional sub-frame, through CQI(Channel Quality Indicator) measurement for each sub-frame period, constraint conditions were measured according to system situations. For the simplification, the pattern of the same ABS muting was assumed. In the above two multi-cell environments, the algorithm of high-speed load balancing maintenance was proposed.

• Toxicological Research
• /
• v.32 no.3
• /
• pp.251-258
• /
• 2016

Mesenchymal stem cells (MSCs) have been identified in multiple types of tissue and exhibit characteristic self-renewal and multi-lineage differentiation abilities. However, the possibility of oncogenic transformation after transplantation is concerning. In this study, we investigated the tumorigenic potential of umbilical cord blood-derived MSCs (hUCB-MSCs) relative to MRC-5 and HeLa cells (negative and positive controls, respectively) both in vitro and in vivo. To evaluate tumorigenicity in vitro, anchorage-independent growth was assessed using the soft agar colony formation assay. hUCB-MSCs and MRC-5 cells formed few colonies, while HeLa cells formed a greater number of larger colonies, indicating that hUCB-MSCs and MRC-5 cells do not have anchorage-independent proliferation potential. To detect tumorigenicity in vivo, hUCB-MSCs were implanted as a single subcutaneous injection into BALB/c-nu mice. No tumor formation was observed in mice transplanted with hUCB-MSCs or MRC-5 cells based on macro- and microscopic examinations; however, all mice transplanted with HeLa cells developed tumors that stained positive for a human gene according to immunohistochemical analysis. In conclusion, hUCB-MSCs do not exhibit tumorigenic potential based on in vitro and in vivo assays under our experimental conditions, providing further evidence of their safety for clinical applications.

• Archives of Pharmacal Research
• /
• v.25 no.6
• /
• pp.895-902
• /
• 2002

Monocytes and macrophages playa major role in defense mechanism of the host response to tumor, in part through the secretion of several potent products and macrophage cytokines. Monocytes and tissue macro phages produce at least two groups of protein mediators of inflammation, interleukin 1 (IL-1) and tumor necrosis factor (TNF). Recent studies emphasizes that TNF and IL-1 modulate the inflammatory function of endothelial cells, leukocytes, and fibroblasts. In this study, our work is directed toward studying the in vitro effects of Korean propolis on the ability to induce cellular and secretory responses in murine macrophage cell line, RAW 264.7. It was found that Water Extract of Korean Propolis (WEP) could activate macro phages by producing cytokines. The production of the macrophage cytokines, IL-1 and TNF-$\alpha$, by RAW 264.7 treated with WEP was examined from 2.5 $\mu\textrm{g}$/ml up to 25 $\mu\textrm{g}$/ml with dose dependent manner. Nitric oxide (NO) production was also increased when cells were exposed to combination of LPS and WEP from 2.5 $\mu\textrm{g}$/ml up to 25 $\mu\textrm{g}$/ml. At high dose of WEP (50 to 100 $\mu\textrm{g}$/ml) used to prescribe for anti-inflammatory and analgesic medicine showed inhibition of NO production in LPS-stimulated macrophage. Besides cytokine production, NO release, surface molecule expression and cell morphologic antigen expression were increased in response to the stimulation by WEP. These results suggested WEP may function through macrophage activation.

• JSTS:Journal of Semiconductor Technology and Science
• /
• v.17 no.2
• /
• pp.167-173
• /
• 2017

In this paper, the characterization of the vertical position of trapped charges in the charge-trap flash (CTF) memory is performed in the novel CTF memory cell with gate-all-around structure using technology computer-aided design (TCAD) simulation. In the CTF memories, injected charges are not stored in the conductive poly-crystalline silicon layer in the trapping layer such as silicon nitride. Thus, a reliable technique for exactly locating the trapped charges is required for making up an accurate macro-models for CTF memory cells. When a programming operation is performed initially, the injected charges are trapped near the interface between tunneling oxide and trapping nitride layers. However, as the program voltage gets higher and a larger threshold voltage shift is resulted, additional charges are trapped near the blocking oxide interface. Intrinsic properties of nitride including trap density and effective capture cross-sectional area substantially affect the position of charge centroid. By exactly locating the charge centroid from the charge distribution in programmed cells under various operation conditions, the relation between charge centroid and program operation condition is closely investigated.

• Journal of the Korea Institute of Information and Communication Engineering
• /
• v.19 no.6
• /
• pp.1307-1312
• /
• 2015

As smart-phones become popular, mobile data traffic has been dramatically increasing and intensive researches on the next-generation mobile communication network is in progress to meet the increasing demand for mobile data traffic. In particular, heterogeneous network (HetNet) is attracting much interest because it can significantly enhance the network capacity by increasing the spatial reuse with macro and small cells. In the HetNet, we have several problems such as load imbalance and interference because of the difference in transmit power between macro and small cells and cell range expansion (CRE) can mitigate the problems. In this paper, we propose a new cell selection scheme with adaptive cell range expansion bias (CREB) for ultra dense HetNet and we analyze the performance of the proposed scheme in terms of average cell transmission rate through system-level simulations and compare it with those of other schemes.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
• /
• 2015.05a
• /
• pp.63-66
• /
• 2015

As smart-phones become popular, mobile data traffic has been dramatically increasing and intensive researches on the next-generation mobile communication network is in progress to meet the increasing demand for mobile data traffic. In particular, heterogeneous network (HetNet) is attracting much interest because it can significantly enhance the network capacity by increasing the spatial resue with macro and small cells. In the HetNet, we have several problems such as load imbalance and interference because of the difference in transmit power between macro and small cells and cell range expansion (CRE) can mitigate the problems. In this paper, we propose a new cell selection scheme with adaptive cell range expansion bias (CREB) for ultra dense HetNet and we analyze the performance of the proposed scheme in terms of average cell transmission rate through system-level simulations and compare it with those of other schemes.