• 한국컴퓨터정보학회논문지
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• 제14권9호
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• pp.11-19
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• 2009

다중 판별자를 가지는 RAM 기반 신경망은 단일판별자의 신경 망보다 다범주에서 더 우수한 성능 가진다. 다중 판별자를 가지는 경험유관이진신경망과 3차원 뉴로 시스템(3DNS)은 RAM 기반 이진신경망의 단점인 추가 및 반복 학습, 일반화 패턴 추출 등을 개선하였다. 다중 판별자를 사용하는 신경망의 범주 결정 방법은 MRD 기법으로, 각 판별자의 출력합들 중 최대응답 값으로 결정된다. 그러나 학습 패턴량이 증가하면 신경소자와 판별자의 메모리 포화 문제가 발생되며 이는 MRD의 변별력 저하로 전체 성능이 떨어지는 원인이 된다. 이를 해결하기 위해 기존 MRD의 성능을 향상시킬 수 있는 연구가 필요하다고 본다. 본 논문에서는 최적의 MRD 방법을 찾기 위해 사상 매칭, 누적 필터비 인형 응답 차 그리고 제안된 MRD 기법들을 이용한 최적 MRD 기법 등을 제안하였다. 제안된 MRD의 평가는 3DNS에 전처리 과정 없이 MNIST의 NIST에서 제공하는 숫자 자료를 이용하였다. 제안된 기법들은 기존 MRD보다 우수한 인식률과 입력 패턴의 변형 및 노이즈에 대하여 안정적인 결과를 보였다.

• 한국미생물·생명공학회지
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• 제21권5호
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• pp.414-420
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• 1993

Escherichia coli mrdAts and mrdBts mutants forming spherical cells at 42C, were employed to investigate the possible role of both inner and outer membrance structures in the determination of cell shape of gram-negative cells. Spherical cells, but not rod-shaped wild types, were specifically killed by anionic detergents, such as sarkosyl, sodium dodecylsulfate and sodium deoxycholate. From the spherical intact cells grown overnight at 42C, much more proteins were released by sakosyl.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2001년도 추계학술발표논문집 (하)
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• pp.1355-1358
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• 2001

IP Multicast can efficiently provide enormous bandwidth savings by enabling sources to send a single copy of a message to multiple recipients who explicitly want to receive the information. But due to the complexity of IP multicast and its fundamental differences from unicast, there are not very many tools available fer monitoring and debugging multicast networks, and only a few experts understand the tools that do exist. This thesis proposes a Multicast Routing Debugger (MRD) system that monitor the status of a multicast network. This system is aimed to multicast-related faults detection. In thesis, first, we define the set of information that should be monitored. Second, the method is developed to take out such information from multicast routers. Third, MRD system is prototyped to collect, process information from heterogeneous routers on a multicast network and to display the various status of the network comprehensively. The prototype of MRD system is implemented and deployed. We perform experiments with several scenarios. Experimental results show we can detect various problems as information that we define is monitored. The MRD system is simple to use, web-based and intuitive tool that can monitor the status of a specific multicast network.

• Archives of Plastic Surgery
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• 제49권4호
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• pp.473-478
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• 2022

Background We investigate the effect of involutional blepharoptosis (IB) surgery based on dry eye symptoms by analysis using objective and subjective measures. Methods We recorded various parameters from patients that underwent levator advancement surgery for IB, totaling 125 eyes (total 65 patients, 5 unilateral, 60 bilateral). Subjective assessment comprised a questionnaire on dry eye-related quality of life score (DEQS), a summary score calculated from DEQS, and six-grade evaluation, the patient's own measure of eye comfort. Objective assessment comprised marginal-reflex distance-1 (MRD-1), measurement of tear film breakup time, and superficial keratopathy (SPK) existence by slit lamp microscope. Results Subjective assessments showed that IB patients had improvement of dry eye symptoms and eye comfort when surgery increased MRD-1. On the other hand, objective assessments showed that the presence of SPK is suspected when the postoperative MRD-1 level is 3 mm or higher. Conclusion IB surgery must not only increase MRD-1 value, but also to perform maintenance of the appropriate ocular surface condition. From our parameters, we suggest postoperative MRD-1 value should be maintained at < 3 mm to safe and effective of IB surgery.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2004년도 제22회 춘계학술대회논문집
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• pp.634-643
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• 2004

In this paper are presented a concept of a new supersonic air inlet, which is designated a Multi-Row Disk (MRD) inlet, aiming at performance improvement under off-design conditions, and results of wind tunnel tests examined performance characteristics of the MRD inlet. The MRD inlet is frequently called ‘a skeleton inlet’ because of its appearance. The performance of a conventional axisymmetric inlet with a solid center body (spike) deteriorates under off-design Mach number conditions. It is due to the fact that total pressure recovery (TPR) governed by the throat area of inlet and mass capture ratio (MCR) governed by an incidence position of an oblique shock from the spike tip into the cowl can not be controlled independently in such air inlet. The MRD inlet has the spike that is composed of a tip cone and several disks arranged downstream of it, based on the experimental fact that several deep cavities on a conical surface have little negative effect on the boundary layer growth. The overall spike length of the MRD inlet is adjustable to the given flight speed by changing space between disks so that a spillage flow can be controlled independently from controlling the throat area. It could be made clear from the result of wind tunnel tests that the MRD inlet improves TPR by 10% compared with a conventional inlet with a solid spike under off-design conditions.

• 대한두개안면성형외과학회지
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• 제14권1호
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• pp.36-40
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• 2013

Background: Correction of unilateral blepharoptosis is unexpectedly difficult because healthy eye is often affected by Hering's law. Methods: We measured changes of marginal reflex distance (MRD1) on the unaffected eyelids between preoperative and 3-month postoperative photographs after ptosis correction. This study analyzed 134 unilateral blepharoptosis patients with ptosis correction from February 2002 to February 2011. Fifty patients among them were negative in Hering's law dependence test. From the preoperative and postoperative photographs the MRD1 of unaffected upper eyelids were measured and adjusted with the average pupil diameter of Koreans. Mean age was 34.4 and male was 30 and female was 20. Average follow-up periods were 14 months. Results: Thirteenth unaffected eyes (26%) showed decreased MRD1, and 3 patients (6%) showed decreased MRD1 value over 1.0 mm. Then 3 patients needed additional operations for correction of preoperatively unaffected but ptotic eyelids. Conclusion: There were no meaningful data statistically in the value of MRD1 in every unaffected eye of the patients and in the difference between preoperative and postoperative MRD1 of groups divided according to severity, causes, and types of operation.

• Clinical and Experimental Pediatrics
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• 제53권11호
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• pp.957-964
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• 2010

Purpose: Our study attempted to determine the prognostic significance of minimal residual disease (MRD) detected by a simplified flow cytometric assay during induction chemotherapy in children with B-cell acute lymphoblastic leukemia (B-ALL). Methods: A total of 98 patients were newly diagnosed with precursor B-ALL from June 2004 to December 2008 at the Asan Medical Center (Seoul, Korea). Of those, 37 were eligible for flow cytometric MRD study analysis on day 14 of their induction treatment. The flow cytometric MRD assay was based on the expression intensity of CD19/CD10/CD34 or aberrant expression of myeloid antigens by bone marrow nucleated cells. Results: Thirty-five patients (94.6%) had CD19-positive leukemic cells that also expressed CD10 and/or CD34, and 18 (48.6%) had leukemic cells with aberrant expression of myeloid antigens. Seven patients with ${\geq}1%$ leukemic cells on day 14 had a significantly lower relapse-free survival (RFS) compared to the 30 patients with lower levels (42.9 % [18.7%] vs. 92.0% [5.4%], $P$=0.004). Stratification into 3 MRD groups (${\geq}1%$, 0.1-1%, and <0.1%) also showed a statistically significant difference in RFS (42.9% [18.7%] vs. 86.9% [8.7%] vs. 100%, $P$=0.013). However, the MRD status had no significant influence on overall survival. Multivariate analysis demonstrated that the MRD level on day 14 was an independent prognostic factor with borderline significance. Conclusion: An MRD assay using simplified flow cytometry during induction chemotherapy may help to identify patients with B-ALL who have an excellent outcome and patients who are at higher risk for relapse.

• Archives of Plastic Surgery
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• 제33권4호
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• pp.449-453
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• 2006

Purpose: Perceiving the experience that $MRD_1$ is increased after small-incision double-eyelid operation, it has been statistically verified the improvement of $MRD_1$ retrospectively. Therefore, we suggest new interpretation for Korean-specific small eye and more definite classification for ptosis. Methods: In operation, we made 3 small incisions according to the line designed on upper eyelid and removed some soft tissues including connective tissues. Then, figure-of-8 continuous buried ligation was performed through the incision windows. This study is a retrospective study, measures $MRD_1$ changes and excursion distance change of eyelid margine and eyebrow using pre-and post-operative photos of 14 patients. Results: Postoperative photos were taken on the 4th day and all of 14 patients had an improvement in $MRD_1$ statistically. The excursion distance of upper eyelid was improved in half of patients, though not in the range of statistical verification. It was statistically confirmed that the movement of eyebrow was reduced after operation. Conclusion: It is thought that $MRD_1$ improvement without any operation on levator complex means that soft tissue including connective tissue eliminated in operation restricts the movement of upper eyelid. It is defined such factors as burden factors and such phenomenon as burdened eyelid. It is thougt that Korean's small eye is mainly burdened eyelid and cosmetic improvement may be obtaind even by removing such burden factors.

• Archives of Plastic Surgery
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• 제33권4호
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• pp.521-524
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• 2006

Purpose: The history of biometry dates back to ancient Greek. The ideal body ratio from biometry is used as a guideline in many works of art. Biometry is also used as a medical standard to determine normal or abnormal. Since the biometry of face is so complicated, many surgeons tend to regard preoperative evaluation as a bother and substitute medical records with some photographs. We introduce a new method to measure $MRD_1$ and levator function using digital photographs, which becomes widely used lately. Methods: $MRD_1$ can be measured with the primary-gaze-view photo which is magnified by PhotoshopR 7.0.1. The distance from coneal reflex of ring flash to upper eyelid margin is converted to mm-unit using the piece of ruler attached on the patient's face. Levator function can be measured with up-gaze-view photo and down-gaze-view photo which are superimposed on another. The excursion distance of upper eyelid margin (a) and the excursion distance of eyebrow (b) are measured respectively. The levator function can be assessed through subtraction of two values (a-b). This method is simple and precise and can be applied directly to patient without photos. Results: Using magnified digital photos and computer, this method can reduce personal error and instrumental error. Taking some digital photos doesn't take long time, so it can reduce the effort of preoperative evaluation and discomfort of patients. Conclusion: Digital photo-biometry is useful for retrospective study. Especially reducing personal error, it is useful when the number of specimens is huge. New levator function test is much more useful for Asian-specific eyes than Berke's method allowing frontalis muscle compensation.

• 한국정보관리학회:학술대회논문집
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• 한국정보관리학회 1998년도 제5회 학술대회 논문집
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• pp.227-230
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• 1998

문헌정보학분야의 용어사전을 이용한 자동시소러스 구축을 위한 첫단계로$\ulcorner$문헌정보학 용어사전$\lrcorner$ MRD를 구성하고 이를 이용하여 상위어 자동 추출알고리즘을 개발하였다. MRD구성시 전처리과정을 통하여 상위어 추출에 불필요한 정보가 수록되는 것을 방지하였다. 상위어 추출을 위한 알고리즘 개발은 무작위 표본추출을 통하여 $\ulcorner$문헌정보학 용어사전$\lrcorner$에 기술된 문장의 구문적 특성을 분석한 후, 이 구문정보를 이용하여 수행하였다. 본 연구에서 제시된 알고리즘의 효율성 평가결과 89.4%의 정확도를 보였다.