• The KIPS Transactions:PartC
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• v.11C no.6 s.95
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• pp.835-842
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• 2004

In this paper, we have analyzed the MC-DS/CDMA system with input signal synchronized completely through adjustment of the gain in the PLL loop, by using the hybrid SC/MRC-(2/3) technique, which is said to one of the optimal diversity techniques under the multi-path fading environment, assuming that phase error is defined to the phase difference between the received signal from the multi-path and the reference signal in the PLL of the receiver. Also, assuming that the regarded radio channel model for the mobile communication is subject to the Nakagami-m fading channel, we have developed the expressions and performed the simulation under the consideration of various factor, in the MC/DS-CDMA system with the hybrid SC.MRC-(2/3) diversity method, such as the Nakagami fading index(m), $the\;number\;of\;paths\;(L_p),$ the number of hybrid SC.MRC-(2/3) $diversity\;branches\;(L,\;L_c),$ the number of users (K), the number of subcarriers (U), and the gain in the PLL loop. As a result of the simulation, it has been confirmed that the performance improvement of the system can be achieved by adjusting properly the PLL loop in order for the MC/DS-CDMA system with the hybrid SC/MRC-(2/3) diversity method to receive a fully synchronized signal. And the value of the gain in the PLL loop should exceed 7dB in order for the system to receive the signal with prefect synchronization, even though there might be a slight difference according to the values of the fading index and the spread processing gain of the subcarrier.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.29 no.11A
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• pp.1237-1243
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• 2004

This paper presents and analyses the closed-form expression of the average bit error rate (BER) for an asynchronous direct-sequence code division multiple access (DS-CDMA) system with coherent binary phase shift keying (BPSK) modulation scheme using a maximal ratio combining (MRC) diversity over a Rician fading channel. In addition to the average BER, outage probability, and user capacity of system are estimated as performance measures. The results are general enough so that it includes Rayleigh fading and nonfading channel with zero and infinite Rician factor, respectively, as special cases. The effects of various channel models, processing gains, and diversity orders on the system performances are also considered for the typical multipath delay profiles characterized by Rician fading channel.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.8 no.8
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• pp.1613-1619
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• 2004

Turbo codes of long block sizes have been known to show very good performance in an AWGN channel and the turbo code has been strongly recommended as error correction code for W-CDMA in 3GPP(3rd Generation Partnership Project). Recently, turbo codes of short block sizes suitable for real time communication systems have attracted a lot of attention. Thus, in this paper we consider the turbo code of 1/3 code rate and short frame size of 192 bits in ITU-R channel model. We analyzed the performance of W-CDMA systems of 10MHz bandwidths employing RAKE receiver with not only MRC diversity but also SOVA-based turbo code.

• Journal of Life Science
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• v.17 no.2 s.82
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• pp.185-191
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• 2007

Akt/PKB plays pivotal roles in many physiological responses such as proliferation, differentiation, apoptosis, and angiogenesis. Here we show that tyrosine phosphorylation of Akt/PKB is essential for the subsequent phosphorylation at $Thr^{\308}$. Tyrosine phosphorylation of Akt/PKB was induced by stimulation of COS-7 cells with epidermal growth factor receptor (EGF) and its phosphorylation was significantly enhanced by constitutive targeting of Akt/PKB to the plasma membrane by myristoylation. Interestingly, incubation of affinity purified Myc-tagged Akt/PKB with purified EGF receptor resulted in tyrosine phosphorylation as well as $Ser^{\473}$ phosphorylation of Akt/PKB. In addition, tyrosine-phosphorylated Akt/PKB could directly associate with activated EGF receptor in vitro. Finally, alanine mutation at putative tyrosine phosphorylation site $(Tyr^{\326})$ abolished EGF induced $Thr^{\308}$ phosphorylation of wild type as well as constitutively active form of Akt/PKB. Given these results we suggest here that direct tyrosine phosphorylation of Akt/PKB by EGF receptor could be another mechanism of EGF-induced control of many physiological responses.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.4A
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• pp.307-314
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• 2010

In this paper, a receive diversity combining technique is proposed for single-carrier frequency division multiple access (SC-FDMA)-based cooperative relay systems when discrete Fourier transform (DFT) spreading sizes for mobile station (MS) and relay station (RS) are different. The proposed technique is composed of a DFT spreading size adjustment block, a phase rotation compensation block, a channel phase compensation block, and a receive diversity combining block. The proposed technique is robust to multipath channels and can be operated with a relatively small computational complexity because receive diversity combining is performed with scalar operations in the frequency-domain. It is shown by computer simulation that the proposed receive diversity combining techniques achieve a performance gain over the conventional maximal ratio combining (MRC) techniques for SC-FDMA-based cooperative relay systems.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.12 no.3
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• pp.470-477
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• 2001

Multucarrier code-division multiple access(MC-CDMA) is one of the promising technique for high capacity wireless communication. Hower the carrier phase error and frequency offest cause the performance degradation of MC-CDMA due to the inter-carrier interference. In this work, downlink performance of the partially coherent MC-CDMA is analytically derived in Rayleigh fading channels. The bit error rate sensitivity by combining method, Maxiaml ratio combining (MRC)and Equal gain combining(EGC), is compared as functions of phase errors. multi-user interference, and received signal-to-noise ratio. The results show that the susceptibility for the performance degradation of EGc and MRC is negligible for loop SNR's of above 15 dB and above 10 dB, respectivtely.

• Journal of Communications and Networks
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• v.11 no.3
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• pp.240-247
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• 2009

The results of performance analysis by adopting the channel scenarios characterized as Weibull fading for an multicarrierdirect sequence-coded division multiple access (MC-DS-CDMA) system are proposed in this investigation. On the other hand, an approximate simple expression with the criterion of bit error rate (BER) versus signal-to-noise ratio (SNR) method is derived for an MC-DS-CDMA system combining with maximal ratio combining (MRC) diversity based on the moment generating function (MGF) formula of Weibull statistics, and it associates with an alternative expression of Gaussian Q-function. Besides, the other point of view on the BER performance evaluation of an MC-DS-CDMA system is not only the assumption of both single-user and multi-user cases applied, but the phenomena of partial band interference (PBI) is also included. Moreover, in order to validate the accuracy in the derived formulas, some of the system parameters, such as Weibull fading parameter (${\beta}$), user number (K), spreading chip number (N), branch number (L), and the PBI (JSR) values, etc., are compared with each other in the numerical results. To the best of author's knowledge, it is a brand new idea which proposes the evaluation of the system performance for an MC-DS-CDMA system over the point of view with Weibull fading channel.

• Journal of Life Science
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• v.17 no.1 s.81
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• pp.56-63
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• 2007

Insulin stimulates the fusion of intracellular vesicles containing glucose transporter 4 (GLUT4) with plasma membrane in adipocytes and muscle cells. Here we show that adipocyte differentiation results in enhanced insulin sensitivity of glucose uptake. On the other hand, glucose uptake in response to platelet-derived growth factor (PDGF) stimulation was markedly reduced by adipocyte differentiation. Expression level of insulin receptor and caveolin-1 was dramatically increased during adipocyte differentiation. Adipocyte differentiation caused :ilightly enhanced activation of acutely transforming retrovirus AKT8 in rodent T cell lymphoma (Akt) by insulin stimulation. However, activation of Akt by PDGF stimulation was largely reduced. Activation of ERK was not detected in both fibroblasts and adipocytes after stimulation with insulin. PDGF-dependent activation of ERK was reduced by adipocyte differentiation. Insulin-dependent glucose uptake was abrogated by LY294002, a phosphatidylinositol 3-kinase (PI3K) inhibitor, in both fibroblasts and adipocytes. Also disassembly of caveolae structure by $methyl-\beta-cyclodextrin$ caused impairment of Akt activation and glucose uptake. Finally, insulin receptor, Akt, SH2-domain-containing inositol 5-phosphatase 2 (SHIP2), and regulatory subunit of PI3K are localized at lipid raft domain and the translocation was facilitated upon insulin stimulation. Given these results, we suggest that lipid raft provide proper site for insulin action for glucose uptake.

• The Journal of Korean Medicine
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• v.41 no.3
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• pp.162-172
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• 2020

Objectives: The purpose of study was to report the clinical improvement of Chronic Obstructive Pulmonary Disease (COPD) patients treated with Korean medicine pulmonary rehabilitation. Methods: The patients were treated with Lung-conduction exercise, Chuna manual therapy, Exercise therapy. To assess the treatment outcomes, we used the pulmonary function test (PFT), modified medical research council scale (mMRC), 6-minute walk distance (6MWD), peak expiratory flow rate (PEFR), COPD assessment test (CAT), St. George respiratory questionnaire (SGRQ). Results: After treatments, the patient's clinical symptoms were improved with CAT, SGRQ's significant decrease and PFT, mMRC, 6MWD and PEFR were maintained or improved slightly. Conclusions: The Korean medicine pulmonary rehabilitation was effective in the treatment of COPD patients. This study suggested the possibility of Korean Medicine pulmonary rehabilitation program in the clinic.

• The Journal of Korean Medicine
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• v.43 no.1
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• pp.171-179
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• 2022

Objectives: The purpose of study was to report the clinical improvement of late complications of COVID-19 patient complaining of dyspnea treated with Korean medicine pulmonary rehabilitation. Methods: To assess the treatment outcomes, we used the modified medical research council scale (mMRC), 6-minute walk distance (6MWD), peak expiratory flow rate (PEFR), St. George respiratory questionnaire (SGRQ). Results: After treatments, the patient's clinical symptoms were improved with mMRC, 6MWD, PEFR, and SGRQ. Conclusions: The Korean medicine pulmonary rehabilitation was effective in the treatment of late complications of COVID-19 patient. This study suggested the possibility of Korean Medicine pulmonary rehabilitation program in the clinic for late complications of COVID-19.