• 말소리와 음성과학
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• 제4권1호
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• pp.125-131
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• 2012

The patients with incomplete glottic closure have an important feature decreasing the maximum phonation time (MPT) because airflow rate or air leakage is greater than people without voice disorders. Also they can appear a problem in the intensity regulation. This study analyzed MPT difference based on the comfortable intensity and louder intensity and the correlation between MPT and respiration volume of unilateral vocal fold palsy (UVFP) and sulcus vocalis (SV) group. The twenty with UVFP, the 21 with SV, the 21 normal subjects measured MPT in /a/ vowel prolongation task with comfortable intensity and louder intensity and compared analysis by measuring FVC, $FEV_1$, $FEV_1/FVC$ to analyze the correlation between MPT and respiration volume. First, a comparison of MPT according to the intensity between groups is that MPT of the normal group was statistically significant long compared to the patient group in comfortable intensity, but MPT between groups was not statistically significant difference in the louder intensity. Second, an analysis of the correlation between MPT and respiration volume is that this was statistically significant correlation between MPT in comfortable intensity and MPT in louder intensity. But this did not show statistically significant correlation between intensity and respiration volume. This study can be supported the preceding study results deduced that shorting MPT of the patient group compared to the normal group was originated in the problem of laryngeal valving mechanism at the level of vocal folds rather than a problem of respiratory function. Also at the phonation by varying the intensity, the result can deduce that in the case of patient group, the length of MPT had been improved by increasing the glottal closure ratio in the louder intensity. These results can support the theoretical basis that should be applied to the clinicians by varying the intensity at the voice evaluation and voice therapy for the patients with the glottis incompetence.

• Journal of Veterinary Science
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• 제23권3호
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• pp.50.1-50.12
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• 2022

Background: There is an urgent need to find reliable and rapid bovine tuberculosis (bTB) diagnostics in response to the rising prevalence of bTB worldwide. Toll-like receptor 2 (TLR2) recognizes components of bTB and initiates antigen-presenting cells to mediate humoral immunity. Evaluating the affinity of antigens with TLR2 can form the basis of a new method for the diagnosis of bTB based on humoral immunity. Objectives: To develop a reliable and rapid strategy to improve diagnostic tools for bTB. Methods: In this study, we expressed and purified the sixteen bTB-specific recombinant proteins in Escherichia coli. The two antigenic proteins, MPT70 and MPT83, which were most valuable for serological diagnosis of bTB were screened. Molecular docking technology was used to analyze the affinity of MPT70, MPT83, dominant epitope peptide of MPT70 (M1), and dominant epitope peptide MPT83 (M2) with TLR2, combined with the detection results of enzyme-linked immunosorbent assay to evaluate the molecular docking effect. Results: The results showed that interaction surface Cα-atom root mean square deviation of proteins (M1, M2, MPT70, MPT83)-TLR2 protein are less than 2.5 A, showing a high affinity. It is verified by clinical serum samples that MPT70, MPT83, MPT70-MPT83 showed good diagnostic potential for the detection of anti-bTB IgG and M1, M2 can replace the whole protein as the detection antigen. Conclusions: Molecular docking to evaluate the affinity of bTB protein and TLR2 combined with ELISA provides new insights for the diagnosis of bTB.

• 대한화학회지
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• 제44권6호
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• pp.573-580
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• 2000

MPT는 최근에 개발된 마이크로파 플라즈마로서 수용매에 강하다. 여러 가지의 변형된 형태의 MPT를 개발하여 구조에 따른 플라즈마의 방전되는 형태를 조사한 결과 이중관 토치는 플라즈마 기체를 적게 소모하며 쉽게 플라즈마가 형성되었으나 토치의 끝이 높은 온도에 견디지 못하고 쉽게 상했다. ICP토치와 같은 형태의 삼중관 토치에 석영관을 중심관으로 사용할 때 가장 안정되고 대칭적인 플라즈마를 형성할 수 있었다. 바탕선을 조사해 본 결과 He MPT는 대기 중으로 돌출되어 대기와 많이 혼합되고 질소에 의해 quenching되는 것으로 보여진다. Membrane desolvator를 탈용매화 장치로 사용하여 헬륨 MPT의 감도를 조사해 본 결과 아르곤 MPT와 비교할 때 대부분의 원소에 대해 검출한계가 10배 이상 높았다. 그러나 여기 에너지가 높은 원소는 비교적 효율적으로 검출할 수 있었다. 헬륨 마이크로파 플라즈마는 적은 양의 플라즈마 기체만 필요하여(약 1.6 L/min) 경제적이며 매우 안정된 형태를 보여주었다. 플라즈마의 분광특성을 조사한 결과 들뜸온도 4950K, 전자밀도 $3.28{\times}10^{14}cm^{-3}$로 측정되었다.

• E2M - 전기 전자와 첨단 소재
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• 제9권2호
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• pp.138-145
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• 1996

A multilayer piezoelectric transformer (MPT) which generates a high voltage dc power with low driving voltage and high voltage setup ratio was made by the tape casting method. The measured electrical characteristics of the MPT agreed with the results simulated from the equivalent circuit of the MPT. With increasing the number of layer in the MPT, the resonance curve of the input cur-rent revealed an asymmetry due to the increasing input capacitance, while that of output dc voltages revealed symmetry. The MPT which has very thin layer was excellently characterized as low driving voltage and high voltage setup ratio. The output dc voltage is nonlinearly influenced by the number of layer in the MPT.

• 말소리와 음성과학
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• 제15권2호
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• pp.31-40
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• 2023

목적: 물 속에서 튜브 발성은 semi-occluded vocal tract(SOVT) 연습 중 하나로 환자가 튜브를 물 속에 잠기게 하여 거품을 내면서 발성을 하는 것으로 음성 훈련에 널리 사용되어 왔다. 본 연구는 과기능성 음성장애 환자를 대상으로 물저항발성 동안 튜브 직경과 튜브를 담그는 물 깊이가 물거품 높이와 최대발성지속시간(maximum phonation time, MPT)에 미치는 영향을 조사하는 것을 목적으로 한다. 방법: 과기능성 음성장애 환자 17명에게 튜브 직경(5, 7, 10 mm), 튜브를 담그는 물 깊이(4, 7, 10 cm)에 따라 지속적인 /u/발성을 하면서 거품을 내도록 하였다. 물거품 높이 및 MPT 기록을 위해 수위 센서를 이용한 물저항발성 바이오피드백 시스템을 사용하였다. 결과: 물거품 높이는 튜브 직경에 의해 유의하게 변화한 반면 MPT는 튜브 직경과 깊이에 따라 유의하게 변화하였다. 직경이 더 넓을수록 주어진 깊이에 대해 유의하게 낮은 물거품 높이를 나타냈지만, 상대적으로 일관된 버블 높이가 유지되었다. 물의 깊이에 따라 주어진 튜브 직경에서 물거품 높이는 유의한 차이가 없었으나, 물의 깊이에 따라 MPT는 유의하게 감소하였고 튜브가 넓을수록 MPT가 유의하게 감소하였다. 결론: 수위 센서 방식의 물저항 바이오피드백 시스템은 튜브 직경 및 수심에 따른 기포 특성 및 성대 진동에 대해 유용한 정보를 제공하였다. 또한, 수위센서를 이용한 물저항발성 바이오시스템은 과기능적 음성장애가 있는 환자의 물저항 발성 중 호흡 지지를 모니터링하는 데 유용하게 사용될 수 있다.

• 한국식품영양학회지
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• 제21권1호
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• pp.71-78
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• 2008

This study examined the effects of mulberry-leaf powder Tofu(MPT) on the anthropometric measurements, bone mineral density(BMD), biochemical markers of bone turnover, serum lipid levels of and macrominerals status in 30 female university students living in Choongnam with low dietary Ca intake was low(mean daily $intake=524.66{\pm}21.47$ mg/day). The subjects received the MPT supplemented(100 g/day) for 4 weeks. The nutrient content per 100 g MPT was 84.10 kcal(energy), 8.98 g(protein), 0.53 mg(fiber), 211.33 mg(Ca) and 1.59 g(fat). Anthropometric measurements, 24-hour dietary recall, carpus BMD using DEXA, select BMD biomarckers(serum alkaline phophatase activity, osteocalcin, urinary deoxypyridinoline), serum protein levels, albumin, and glucose levels, lipid profiles(cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol) and serum macrominerals(Ca, Ca/P ratio, Mg) were analyzed before and after MPT supplementation. Following MPT supplementation, there was no significant differences in anthropometric measurements, nutrient intakes, carpus BMD, serum alkaline phosphatase activity, osteocalcin, and urinary deoxypyridinoline, serum levels of protein, albumin, and glucose or lipid profiles with AI, HTR, LHR and CRF. However, there were significant increases in dietary calcium as well as decreases in serum triglycerides with MPT supplementation. Although further research is needed, these results that regular intake MPT could prevent bone and cardiovascular diseases.

• 월간낙농육우
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• 제27권6호통권302호
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• pp.138-142
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• 2007

MPT 관리는 젖소, 육우의 혈액 성상을 판독해 영양대사 장애의 원인을 발견하고 그 대책을 종합적으로 조언해주는 서비스이다. 이를 잘 활용하면 젖소의 경제수명을 최대한 늘려주고 영양장애로부터 유발되는 각종 질병치료비도 절감시켜주는 등 경제효과가 크다. 다만, 소기의 효과를 거두기 위해서는 낙농비육농가와 MPT전문가와의 유기적인 협조가 중요하다.

• 한국자동차공학회논문집
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• 제5권3호
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• pp.106-116
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• 1997

In this paper, using MATLAB SIMULINK, a generalized design methodology was suggested for multi pass transmission(MPT) by classifying the vehicle power train as prime mover, MPT and vehicle dynamics. This approach enables a designer to investigate the influence of each transmission component by simple combination of system components without changes of overall program. Using the design methodology, a MPT consisting of CVT, 2, clutches and reduction gears was designed for a braking energy regenerative flywheel hybrid vehicle. The CVT is essential in order to connect the engine and flywheel speed with the vehicle speed. For the purpose of smooth clutch operation, control algorithm was suggested by introducing dead zone for the clutch engagement. Using the SIMULINK model, performance of the flywheel hybrid vehicle with MPT was investigated. It was observed from the simulation results that the MPT vehicle showed better fuel economy, 47% than that of AT vehicle, 27% than that of CVT vehicle for ECE-15 driving cycle. Especially destinct fuel efficiency improvement was obtained for city driving cycle requiring more frequent stop and start.

• 한국전기전자재료학회논문지
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• 제19권12호
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• pp.1099-1105
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• 2006

In this paper, the equivalent circuit model of a Rosen-type multilayer piezoelectric transformer(MPT) has been proposed based on the Mason's equivalent circuit model and the principle of single layer piezoelectric plate. From the piezoelectric direct and converse effects, the symbolic expressions between the electric inputs and outputs of the MPT have been derived from the equivalent circuit model. A simplified equivalent circuit model of the MPT whose driving part has a single input form has been proposed. The symbolic expressions of the driving part have been derived from the simplified equivalent circuit model and the model was compared with the multi-input equivalent circuit model through the simulation. In the comparisons between the simulation results and the experimental data, output voltage is 630 Vp-p in case of 11-layered MPT and 670 Vp-p for 13-layered MPT over the experiment range. As the load resistance increases, output voltage increases and saturates over $300k{\Omega}$ and the resonant frequency changes from 102 kHz to 103 kHz. The simulation and the experimental results agree well over different load resistances and frequencies.

• 대한후두음성언어의학회지
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• 제13권2호
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• pp.117-123
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• 2002

MIP was significantly increased in singers, compared to the untrained group. MIP in patients showed decreasing tendency compared to the untrained group, but were significantly lower than that in singers. MEP in singers was higher than that in the untrained group. MPT increased significantly in singers, but diminished in patients compared to the untrained group. MIP, MEP, and MPT in male singers were 50.8%, 61.0%, and 28.7 % higher than those in female singers. MIP, MEP, and MPT in the untrained male were more increased 32.3%, 25.0%, and 28.7%, respectively than those in the untrained female. There was no correlation between MPT and MIP or MEP. Regression analysis of the data set showed that weight and vocal cord dysfunction was a positive predictor of MPT. Factors affecting MIP were male, singers and weight. Factors affecting MEP were male, singers, vocal cord dysfunction and weight.