• Title/Summary/Keyword: MPT

Search Result 169, Processing Time 0.106 seconds

Comparison of Maximum Phonation Time Associated with the Changes in Vocal Intensity in Patients with Unilateral Vocal Fold Palsy and Sulcus Vocalis (성대마비와 성대구증의 강도 변화에 따른 최대발성지속시간 비교)

  • Choi, Se-Jin;Choi, Hong-Shik;Kim, Jae-Ock;Choi, Yae-Lin
    • Phonetics and Speech Sciences
    • /
    • v.4 no.1
    • /
    • pp.125-131
    • /
    • 2012
  • The patients with incomplete glottic closure have an important feature decreasing the maximum phonation time (MPT) because airflow rate or air leakage is greater than people without voice disorders. Also they can appear a problem in the intensity regulation. This study analyzed MPT difference based on the comfortable intensity and louder intensity and the correlation between MPT and respiration volume of unilateral vocal fold palsy (UVFP) and sulcus vocalis (SV) group. The twenty with UVFP, the 21 with SV, the 21 normal subjects measured MPT in /a/ vowel prolongation task with comfortable intensity and louder intensity and compared analysis by measuring FVC, $FEV_1$, $FEV_1/FVC$ to analyze the correlation between MPT and respiration volume. First, a comparison of MPT according to the intensity between groups is that MPT of the normal group was statistically significant long compared to the patient group in comfortable intensity, but MPT between groups was not statistically significant difference in the louder intensity. Second, an analysis of the correlation between MPT and respiration volume is that this was statistically significant correlation between MPT in comfortable intensity and MPT in louder intensity. But this did not show statistically significant correlation between intensity and respiration volume. This study can be supported the preceding study results deduced that shorting MPT of the patient group compared to the normal group was originated in the problem of laryngeal valving mechanism at the level of vocal folds rather than a problem of respiratory function. Also at the phonation by varying the intensity, the result can deduce that in the case of patient group, the length of MPT had been improved by increasing the glottal closure ratio in the louder intensity. These results can support the theoretical basis that should be applied to the clinicians by varying the intensity at the voice evaluation and voice therapy for the patients with the glottis incompetence.

A combined application of molecular docking technology and indirect ELISA for the serodiagnosis of bovine tuberculosis

  • Song, Shengnan;Zhang, Qian;Yang, Hang;Guo, Jia;Xu, Mingguo;Yang, Ningning;Yi, Jihai;Wang, Zhen;Chen, Chuangfu
    • Journal of Veterinary Science
    • /
    • v.23 no.3
    • /
    • pp.50.1-50.12
    • /
    • 2022
  • Background: There is an urgent need to find reliable and rapid bovine tuberculosis (bTB) diagnostics in response to the rising prevalence of bTB worldwide. Toll-like receptor 2 (TLR2) recognizes components of bTB and initiates antigen-presenting cells to mediate humoral immunity. Evaluating the affinity of antigens with TLR2 can form the basis of a new method for the diagnosis of bTB based on humoral immunity. Objectives: To develop a reliable and rapid strategy to improve diagnostic tools for bTB. Methods: In this study, we expressed and purified the sixteen bTB-specific recombinant proteins in Escherichia coli. The two antigenic proteins, MPT70 and MPT83, which were most valuable for serological diagnosis of bTB were screened. Molecular docking technology was used to analyze the affinity of MPT70, MPT83, dominant epitope peptide of MPT70 (M1), and dominant epitope peptide MPT83 (M2) with TLR2, combined with the detection results of enzyme-linked immunosorbent assay to evaluate the molecular docking effect. Results: The results showed that interaction surface Cα-atom root mean square deviation of proteins (M1, M2, MPT70, MPT83)-TLR2 protein are less than 2.5 A, showing a high affinity. It is verified by clinical serum samples that MPT70, MPT83, MPT70-MPT83 showed good diagnostic potential for the detection of anti-bTB IgG and M1, M2 can replace the whole protein as the detection antigen. Conclusions: Molecular docking to evaluate the affinity of bTB protein and TLR2 combined with ELISA provides new insights for the diagnosis of bTB.

Development and Characterization of Helium Microwave Plasma Torch (헬륨 마이크로파 플라즈마 토치의 개발과 특성에 관한 연구)

  • Jo, Kyung Hyun;Pak, Yong Nam
    • Journal of the Korean Chemical Society
    • /
    • v.44 no.6
    • /
    • pp.573-580
    • /
    • 2000
  • MPT, which has been developed recently, is very tolerant to aqueous samples. Several types of MPT have been investigated and is found that the double concentric tube could sustain a stable plasma at a low plasma gas flow rate. However, the tip of torch is easily ruined. Triple concentric torch has shown the best stability and the plasma shape, much like that of ICP, especially when the central channel is quartz. The plasma is exposed and mixed with air as is suggested from the background spectrum, which leads to quenching of He MPT. Sensitivity of helium MPT equipped with a membrane desolvator has shown 10 times lower than that of Argon MPT for most of elements except for the ones with relatively high excitation energy. He MPT requires small plasma flow rate (about 1.6 L/min), stable and simple to use. Excitational temperature and electron number density measured are 4950 K and 3.28 ${\times}$ $10^{14}cm^{-3}$, respectively.

  • PDF

Electrical properties of multilayer piezoelectric transformer (적층압전변압기의 전기적 특성)

  • 정수태;조상희
    • Electrical & Electronic Materials
    • /
    • v.9 no.2
    • /
    • pp.138-145
    • /
    • 1996
  • A multilayer piezoelectric transformer (MPT) which generates a high voltage dc power with low driving voltage and high voltage setup ratio was made by the tape casting method. The measured electrical characteristics of the MPT agreed with the results simulated from the equivalent circuit of the MPT. With increasing the number of layer in the MPT, the resonance curve of the input cur-rent revealed an asymmetry due to the increasing input capacitance, while that of output dc voltages revealed symmetry. The MPT which has very thin layer was excellently characterized as low driving voltage and high voltage setup ratio. The output dc voltage is nonlinearly influenced by the number of layer in the MPT.

  • PDF

Dyeing Properties of Tencel Fabrics Treated with NaOH, Liquid Ammonia (가성소다, 액체암모니아 처리한 텐셀의 염색성)

  • Lee, Myeong-Seon;Bae, So-Yeong
    • Textile Science and Engineering
    • /
    • v.34 no.8
    • /
    • pp.507-516
    • /
    • 1997
  • The purified tencel fabrics were treated with NaOH, liquid ammonia (NH$_3$), NaOH and subsequently NH$_3$, and also market product tencel (MPT) treated arith NH$_3$. Finally the pretreated tencel fabrics were processed with enzyme (cellulase). The crystalline structure, SEM, moisture regain, water absorbency, tensile strength, and dyeing behavior of the specimens were studied. The degree of crystallinities decreased in the order of MPT-NH$_3$ > NaOH/MH$_3$ ) MH$_3$ > NaOH > MPT > untreated tencel. However moisture regain and water absorbency of the NH$_3$-treated tencel were lower than those of the untreated because of swelling characteristic of MH$_3$. The NH$_3$ treated-tencel fabric increased in the dry strength compared to untreated tencel. The increase in rate of dyeing was in the order of NaOH > NaOH > NH$_3$ > MPT-NH$_3$ > MPT > untreated tencel fabrics. The equilibrium exhaustion appeared In the order of NaOH > NaOH/NH$_3$ > MPT-NH$_3$ > untreated > MPT The fiber surface of the NH$_3$-pretreated tencel fabrics was remarkably fibrillated by cellulase treatment. The weight loss by cellulase treatment increased in the order of NaOH/NH$_3$> NH > NaOH-treated tencel fabrics and equilibrium exhaustion decreased by cellulase treatment.

Effects of Mulberry-Leaf Powder Tofu on Carpus Mineral Density, Biochemical Markers of Bone Turnover and Lipid Profiles in Female University Students from Choongnam Consuming Low Calcium Diet (뽕잎 분말 첨가 두부가 충남 일부지역 저칼슘 섭취 여대생의 손목 골밀도, 생화학적 골대사지표 및 지질성상에 미친 영향)

  • Kim, Ae-Jung;Kim, Myung-Hwan;Han, Myung-Ryun;Choi, Mi-Kyeong;Kim, Mi-Hyun;Kang, Nam-Mi
    • The Korean Journal of Food And Nutrition
    • /
    • v.21 no.1
    • /
    • pp.71-78
    • /
    • 2008
  • This study examined the effects of mulberry-leaf powder Tofu(MPT) on the anthropometric measurements, bone mineral density(BMD), biochemical markers of bone turnover, serum lipid levels of and macrominerals status in 30 female university students living in Choongnam with low dietary Ca intake was low(mean daily $intake=524.66{\pm}21.47$ mg/day). The subjects received the MPT supplemented(100 g/day) for 4 weeks. The nutrient content per 100 g MPT was 84.10 kcal(energy), 8.98 g(protein), 0.53 mg(fiber), 211.33 mg(Ca) and 1.59 g(fat). Anthropometric measurements, 24-hour dietary recall, carpus BMD using DEXA, select BMD biomarckers(serum alkaline phophatase activity, osteocalcin, urinary deoxypyridinoline), serum protein levels, albumin, and glucose levels, lipid profiles(cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol) and serum macrominerals(Ca, Ca/P ratio, Mg) were analyzed before and after MPT supplementation. Following MPT supplementation, there was no significant differences in anthropometric measurements, nutrient intakes, carpus BMD, serum alkaline phosphatase activity, osteocalcin, and urinary deoxypyridinoline, serum levels of protein, albumin, and glucose or lipid profiles with AI, HTR, LHR and CRF. However, there were significant increases in dietary calcium as well as decreases in serum triglycerides with MPT supplementation. Although further research is needed, these results that regular intake MPT could prevent bone and cardiovascular diseases.

'건강할 때 건강을 지켜주는' MPT 관리

  • Hong, Gyeong-Seon
    • 월간낙농육우
    • /
    • v.27 no.6 s.302
    • /
    • pp.138-142
    • /
    • 2007
  • MPT 관리는 젖소, 육우의 혈액 성상을 판독해 영양대사 장애의 원인을 발견하고 그 대책을 종합적으로 조언해주는 서비스이다. 이를 잘 활용하면 젖소의 경제수명을 최대한 늘려주고 영양장애로부터 유발되는 각종 질병치료비도 절감시켜주는 등 경제효과가 크다. 다만, 소기의 효과를 거두기 위해서는 낙농비육농가와 MPT전문가와의 유기적인 협조가 중요하다.

  • PDF

A Study on Multi Pass Transmission System for a Flywheel Hybrid Vehicle (플라이휘일 하이브리드 차량의 다경로 동력전달장치 연구)

  • 송한림;김현수
    • Transactions of the Korean Society of Automotive Engineers
    • /
    • v.5 no.3
    • /
    • pp.106-116
    • /
    • 1997
  • In this paper, using MATLAB SIMULINK, a generalized design methodology was suggested for multi pass transmission(MPT) by classifying the vehicle power train as prime mover, MPT and vehicle dynamics. This approach enables a designer to investigate the influence of each transmission component by simple combination of system components without changes of overall program. Using the design methodology, a MPT consisting of CVT, 2, clutches and reduction gears was designed for a braking energy regenerative flywheel hybrid vehicle. The CVT is essential in order to connect the engine and flywheel speed with the vehicle speed. For the purpose of smooth clutch operation, control algorithm was suggested by introducing dead zone for the clutch engagement. Using the SIMULINK model, performance of the flywheel hybrid vehicle with MPT was investigated. It was observed from the simulation results that the MPT vehicle showed better fuel economy, 47% than that of AT vehicle, 27% than that of CVT vehicle for ECE-15 driving cycle. Especially destinct fuel efficiency improvement was obtained for city driving cycle requiring more frequent stop and start.

  • PDF

Agreement of two ELISAs for Mycobacterium avium subspecies paratuberculosis in cattle in Korea

  • Lee, Kyung Woo;Jung, Byeong Yeal;Hwang, In Yeong;Lee, Su Hwa;Kim, Ji Yeon;Kim, Young Hoan;Lee, Seong Hyo;Moon, Oun Kyoung;Lee, O Soo
    • Korean Journal of Veterinary Research
    • /
    • v.49 no.2
    • /
    • pp.121-125
    • /
    • 2009
  • Paratuberculosis caused by Mycobacterium avium subspecies paratuberculosis (Mpt) is a chronic infectious enteric disease with deleterious impact on the performance in ruminants. In Korea, ELISA has been introduced to detect antibodies to Mpt in individual cattle. However, comparison study with ELISA has not been studied until now. In total, a panel of 899 serum samples obtained from dairy cattle was analyzed with two commercial ELISAs for Mpt to assess the performance. Two ELISAs employed in this study were both licensed worldwide. Two ELISAs applied onto same serum samples showed the moderate agreement (kappa value = 0.60). There was non-significant McNemar test (p = 0.0614) between two ELISA results indicating that each proportion detected by two kits did not differ. In addition, the percent agreement between two ELISA results was turned out to be 96.8% which interpreted excellent reproducibility. It was shown from this study that two ELISAs revealed moderate kappa agreement performance. The implication raised is that when ELISAs as diagnostics are used to detect Mpt in individual cattle, positive reaction by either ELISA should be interpreted as serologically Mpt positive due to presumed low sensitivity of ELISAs and their test agreement being less than 100%.

Maximal Inspiratory Pressure, Maximal Expiratory Pressure, and Maximum Phonation Time in Singers, Untrained Normal Person, and Patients with Vocal Cord Diseases (성악가와 성악훈련을 받지 않은 일반인과 성대질환이 있는 환자에서 최대흡기압, 최대호기압, 최대발성지속시간에 관한 연구)

  • 남도현;안철민;최홍식
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
    • /
    • v.13 no.2
    • /
    • pp.117-123
    • /
    • 2002
  • MIP was significantly increased in singers, compared to the untrained group. MIP in patients showed decreasing tendency compared to the untrained group, but were significantly lower than that in singers. MEP in singers was higher than that in the untrained group. MPT increased significantly in singers, but diminished in patients compared to the untrained group. MIP, MEP, and MPT in male singers were 50.8%, 61.0%, and 28.7 % higher than those in female singers. MIP, MEP, and MPT in the untrained male were more increased 32.3%, 25.0%, and 28.7%, respectively than those in the untrained female. There was no correlation between MPT and MIP or MEP. Regression analysis of the data set showed that weight and vocal cord dysfunction was a positive predictor of MPT. Factors affecting MIP were male, singers and weight. Factors affecting MEP were male, singers, vocal cord dysfunction and weight.

  • PDF