• Asian-Australasian Journal of Animal Sciences
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• 제24권7호
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• pp.889-897
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• 2011

Mycoplasma Pneumonia of swine (MPS) decreases the daily growth of pigs, and, co-infection with a virus sometimes causes severe pneumonia. Genetic selection of pigs resistant to the pulmonary MPS lesion might solve the economic loss due to MPS in animal production. Here, we examined the immunophenotype of Landrace line (Miyagino L2), genetically selected to reduce the incidence of pulmonary MPS lesion for 5 generations in Miyagi Prefecture Animal Industry Experiment Station. Although this line is expected to be resistant to the pulmonary MPS lesion, the biological characteristics of its immune function are not clear. We investigated details of the immunorelated phenotype of Miyagino L2 at the hematological and molecular biological level, including cytokine expression, and compared the results with that of non-genetically selected Landrace. Miyagino L2 showed decreased antigen-specific IgG and IgM production and increased CD8-positive T-cell population, and high levels of cortisol concentration, suggesting that the MPS-resistant phenotype is associated these immunological differences. Additionally, T-cell CD4 expression was highly correlated with the MPS expected breeding value. Although the detailed mechanisms underlying this high correlation remain unknown, our result suggested that the genetic selection of the expression level of CD4 might be useful to improve MPS resistance in pig production.

• 대한수의학회지
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• 제42권2호
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• pp.219-224
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• 2002

We report the seasonal prevalence of the mycoplasmal pneumoniae of swine (MPS) in slaughter pigs from July of 1999 to June of 2000. Gross finding of lung lesion observed and examined by dot-ELISA. In gross finding of lung lesion from 750 pig samples, 465 (62.0%) was MPS, and 129 (17.2%) was single or double infection with actinobacillosis and pasturellosis. However, 156 (20.8%) had no lesion. In seasonal detection, the prevalence was found to be winter (69.5%), autumn (63.5%), summer (60.0%) and spring (54.7%) in orderly frequency. In dot-ELISA, the result was showed the positive reaction (x16>titre) with 58.0% and negative (x4

• Clinics in Shoulder and Elbow
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• 제20권3호
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• pp.138-146
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• 2017

Background: Arthroscopic fixations for large and comminuted bony Bankart lesions are technically difficult. We developed an arthroscopic multiple pulled suture (MPS) technique to restore large and comminuted bony Bankart lesions. Methods: Ten patients (mean age, 49.8 years; range, 31-79 years) underwent bony Bankart repair using the illustrated MPS technique and were then followed for a mean of 27.3 months. A plain radiograph series and three-dimensional computed tomography scans were taken at the initial clinical evaluation and 3 months postoperatively. Outcome measurements included the American Shoulder and Elbow Surgeons (ASES) score, Rowe score, University of California at Los Angeles (UCLA) score, and subjective patient satisfaction, along with surgical complications. Results: Union of an osseous fragment with the glenoid rim was confirmed in all patients on a computed tomography scan 3 months after operation. The osseous fragment was restored to proper articular congruence and reduction. The affected shoulder was stable in nine of the 10 patients. One patient presented with a redislocation after a sports injury 3 years postoperatively. The ASES, Rowe, and UCLA scores improved at the final evaluation, and median patient satisfaction at the final follow-up was 9 of 10 points (range, 6-10 points). Conclusions: The arthroscopic MPS technique for bony Bankart lesions with large or comminuted osseous fragments was a relatively easy and safe method for stable fixation of the osseous fragment. Therefore, the arthroscopic MPS technique resulted in good restoration of stability with high patient satisfaction and low complication rates.

• Nuclear Medicine and Molecular Imaging
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• 제42권1호
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• pp.77-78
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• 2008

A 71-year-old woman was assigned to our department for Tc-99m myocardial perfusion SPECT(MPS) and coronary CT angiography. She admitted for substernal pain, via the ER, 2 days ago. The heart was scanned after intravenous injection of 925 MBq of $^{99m}Tc$-sestamibi adenosine-induced stress SPECT using dual head gamma camera (Hawkeye, GE healthcare. USA). The MPS shows decreased tracer uptake in the apical & mid area of anterior & lateral wall and mid & basal inferior wall. Coronary CT angiograph was obtained using Discovery VCT (GE healthcare). 3D angiography portrayed significant stenosis of ramus intermedius(RI) and posterolateral branch of right coronary artery(PLB) with fibrocalcified plaque. Two images were fused using Cardiac IQ fusion softwear package (Advantage workstation 4.4, GE healthcare) The fusion images explain the perfusion defect of anterior, lateral and inferior wall is due to stenosis of the RI and PLB. And 3 days later, coronary angiography was done and revealed the marked stenosis of RI and PLB. Then balloon angioplasty and stent was instituted in RI. Cardiac SPECT/CT fusion imaging provides additional information about hemodynamic relevance and facilitates lesion interpretation by allowing exact allocation of perfusion defects to its subtending coronary artery.

• Nuclear Medicine and Molecular Imaging
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• 제43권6호
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• pp.513-518
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• 2009

목적: 관상동맥질환은 치료법이 개발되어 있는 매우 치명적인 질환이므로 빠른 진단과 치료방법의 결정 및 재발이나 앞으로의 위험성에 대한 평가가 중요하다. 최근에는 병태생리를 반영하는 심근관류 SPECT와 해부학적 영상인 CT의 퓨전 영상에 대한 기대가 증가되고 있다. 저자들은 심근관류 SPECT에서 가역적인 관류 변화가 있었던 환자에서 퓨전영상의 유용성에 대하여 후향적 분석을 하였다. 대상 및 방법: 다기관 공동 연구로 전국 5개 대학 병원에서 48명의 환자(남:녀=26:22, 나이: $63.3{\pm}10.4$ 세)를 대상으로 하였다. 환자들은 아데노신 약물부하로 Tc-99m 세스타미비 혹은 테트로포스민을 이용하여 휴식기 및 부하기 심근관류 SPECT와 64채널 다중검출 CT를 이용하여 CTA를 시행하였으며, 소프트웨어(CardIQ, GE healthcare)로 두 영상을 퓨전하여 두 검사의 진단 정확도를 비교하였다. 결과: 48명의 환자를 대상으로 144개의 관상동맥에 대하여 분석하였다. 이들 중에서 단일 혈관 질환 환자가 17명, 두혈관 질환 환자가 15명, 세혈관 질환 환자가 11명, 유의한 협착이 없는 환자가 3명이었고, 2명의 환자에서 좌측 주관상동맥의 협착이 발견되었다. 좌측 주관상동맥에 협착이 있었던 2명을 제외하고, 관상동맥의 협착을 진단하는데에 있어 심근관류 SPECT는 민감도 68.8%, 특이도 70.7%이었으며, 퓨전영상은 각각 82.5%, 79.3%, 이었고, 두 검사의 진단 정확도에는 유의한 차이가 있었다(p<0.05). 퓨전영상에서는 좌측 주관상동맥의 협착을 포함하여 전체 82개의 협착 혈관 중 68개의 협착을 진단하였고, 심근관류 SPECT만으로 분석할 때보다 11개의 협착 병변을 추가로 확인할 수 있었다. 또한 애매한 관류저하를 보였던 3개의 관류저하 부위를 허혈 병변에서 제외할 수 있었으며, 4개의 병변은 관류저하를 유발하는 관상동맥을 수정하였다. 3개의 허혈 병변에 대하여서는 허혈 관련 병변 분절을 정확하게 국소화할 수 있었다. 결론: 심근 관류 SPECT와 CTA의 3차원 퓨전 영상은 관상동맥 질환의 병태생리를 포괄적으로 이해할 수 있도록 도움을 주고, 진단의 정확도를 높일 수 있을 것으로 사료된다.