• Journal of Chest Surgery
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• 제51권3호
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• pp.195-201
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• 2018

Background: We investigated the surgical outcomes of patients who underwent therapeutic surgery for malignant pleural mesothelioma (MPM) at a single center. Methods: A retrospective review of 21 patients who underwent therapeutic surgery for MPM from January 2001 to June 2015 was conducted to assess their outcomes. The patients' characteristics and postoperative course, including complications, mortality, overall survival, and recurrence-free survival, were analyzed. Results: Of the 21 patients who underwent therapeutic surgery, 1 5 (71.4%) underwent extrapleural pneumonectomy, 2 pleurectomy (9.5%), and 4 excision (1 9.1 %). The median age was 57 years (range, 32-79 years) and 15 were men (71.4%). The mean hospital stay was 1 6 days (range, 1-63 days). Median survival was 14.3 months. The survival rate was 54.2%, 35.6%, and 21.3% at 1, 3, and 5 years, respectively. In patients' postoperative course, heart failure was a major complication, occurring in 3 patients (14.3%). The in-hospital mortality rate was 2 of 21 (9.5%) due to a case of severe pneumonia and a case of acute heart failure. Conclusion: A fair 5-year survival rate of 21.3% was observed after surgical treatment. Heart failure was a major complication in our cohort. Various surgical methods can be utilized with MPM, each with its own benefits, taking into consideration the severity of the disease and the comorbidities of the patient. Patients with local recurrence may be candidates for surgical intervention, with possible satisfying results.

• 방송공학회논문지
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• 제15권3호
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• pp.380-390
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• 2010

가장 최근에 표준화가 완료된 동영상 압축 코덱인 H.264/AVC는 율-왜곡 최적화를 사용하여 압축률이 상당히 향상되었다. 율-왜곡 최적화는 다수의 후보 모드들 중에서 최적의 모드를 결정하기 위한 수단이며, 모든 모드에 대하여 라그랑지안 비용을 계산하여 그 비용이 가장 적은 모드를 최적의 모드로 결정한다. 하지만 이 방법의 사용으로 인하여 H.264/AVC 부호기의 계산 복잡도가 상당히 증가하였다. 본 논문에서는 H.264/AVC의 화면 내 예측 부호화의 율-왜곡 최적화의 사용으로 인한 계산 복잡도를 감소시키는 고속 화면 내 예측 모드 결정 방법을 제안한다. 제안된 방법은 Intra$4{\times}4$와 Chroma Intra의 부호화 속도를 향상시키기 위하여 최고 확률 모드(MPM)가 가장 최적의 예측 모드인 경우를 미리 판단하여, 이 경우에는 율-왜곡 최적화 과정을 생략하고 최고 확률 모드를 사용하여 부호화한다. 또한 이 방법을 색차 화면 내 예측 모드에 유사하게 적용하였다. 실험 결과, 제안된 방법은 PSNR (Peak Signal-to-Noise Ratio) 손실이 거의 없이 평균 약 63%의 부호화 시간을 절약하였다.

• 한국정보통신학회:학술대회논문집
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• 한국해양정보통신학회 2000년도 추계종합학술대회
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• pp.539-543
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• 2000

본 논문은 7MS320C6x01 DSP프로세서를 이용하여 원격실시간 모니터링 시스템을 설계한 연구로서 시스템구성은 성능, 규격 및 기능 둥의 조건을 수용하는 RFPM, SPM, MPM 모듈로 구성되었다. 실험 및 성능테스트는 WCDMA와 비동기 IMT-2000시스템과 연계하여 측정하였다. 측정결과 40MHz의 입력주파수에 대해 10dB 정도의 노이즈가 분포되었고 요구조건에 부합하는 통합형 원격 기지국 모니터링 운용보전에 적용하였다.

• 한국정보처리학회:학술대회논문집
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• 한국정보처리학회 2003년도 춘계학술발표논문집 (중)
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• pp.1349-1352
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• 2003

웹 서버는 CPU time의 대부분인 $75{\sim}78%$를 시스템 코드에서 소비하며 사용자 코드에서는 생각보다 많은 시간을 소비하지 않는다. 이것은 웹 서버의 성능에 운영체제가 많은 영향을 끼치고 있음을 암시하는 것이다. 본 논문에서는 Linux Trace Toolkit를 이용하여, 하이브리드 멀티 프로세스 멀티 스래드 방식의 아파치 웹 서버가 구동 중인 동안 호출되는 시스템 호출의 동작 과정과 역할에 대해 알아보고 어떤 시스템 코드에서 오버해드가 큰지를 분석하였다.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2003년도 봄 학술발표논문집 Vol.30 No.1 (C)
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• pp.73-75
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• 2003

OFDM 전송방식에 있어서 중요한 주파수 옵셋 추정을 하는데 있어서 기존의 FFT 방법이 가지고 있는 문제점을 보완하는 알고리즘이 많이 연구되고 있다. FFT의 정수배 옵셋외에 소수배 옵셋이 생겼을때 제대로 추정해 낼 수 없는 점을 보완하는 High resolutional technical 알고리즘을 보면 MVDR, MUSIC, root MUSIC, PISARENCO 등이 있다. 본 논문에서는 이러한 알고리즘 중에 MPM(Matrix Pencil Method)를 이용하여 FFT의 문제점을 보완하고 옵셋 추정을 시뮬레이션 해 보았다.

• 전기학회논문지
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• 제67권2호
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• pp.239-247
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• 2018

Adaptive Beamforming (ABF) algorithm, which is a typical jammer suppression algorithm, guarantees the performance on the assumption that the jamming characteristics of the TDS (Training Data Sample) are stationary, which are obtained immediately before and after transmitting the pulse signal. Therefore, effective jammer suppression can not be expected when the jamming characteristics are non-stationary. In this paper, we propose a new jammer suppression algorithm, of which power spectrum fluctuates fast. In this case, we assume that the location of the jammer station is fixed during the processing time. By applying the MPM (Matrix Pencil Method) to the jamming signal in TDS, we can estimate jammer parameters such as power and incident angle, of which the power will vary fast in time or range bins after TDS. Though we assume that the jammer station is fixed, the estimated jammer's incident angle has an error due to the noise, which degrades the performance of the jammer suppression as the jammer power increases fast. Therefore, the jammer's incident angle should be re-estimated at each range bin after TDS. By using the re-estimated jammer's incident angle, we can construct new covariance matrix under the non-stationary jamming environment. Then, the optimum weight for the jammer suppression is obtained by inversing matrix estimation method based on the matrix projection with the estimated jammer parameters as variables. To verify the performance of the proposed algorithm, the SINR (signal-to-interference plus noise ratio) loss of the proposed algorithm is compared with that of the conventional ABF algorithm.

• 한국항해항만학회지
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• 제36권10호
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• pp.833-838
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• 2012

TDOA 기법은 위치추정 기법의 하나로 간단한 구조와 높은 정확도를 가지는 장점으로 인해 실내측위, 재머 위치추적, 인명구조 등에 자주 사용된다. 본 논문에서는 MPM(Matrix Pencil Method)를 이용한 고분해능 TDOA 추정 기법을 제안한다. 제안된 기법은 기존의 교차상관을 이용한 TDOA 기법에 비교하여 높은 정확도를 가지며 협대역 신호에 적용이 가능하다. 또한 잘 알려진 고분해능 기법 중 하나인 MUSIC(Multiple Signal Classification)에서 공분산 행렬을 사용하는 것과 달리 수집된 데이터를 바로 행렬로 만들어 사용하므로 복잡성이 낮은 특징이 있다. 제안된 기법의 성능을 검증하기 위해 소프트웨어 시뮬레이션 통해 추정 오차와 연산량 측면에서 MUSIC 기법과 비교하였다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제26권5호
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• pp.470-480
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• 2000

The epithelium of odontogenic cyst seems to be in a specific status of cellular proliferation and cytodifferentiation. With the identification of various genes, which play essential roles in the specific stages of cellular proliferation and differentiation, the cellular conditions of odontogenic cyst epithelium need to be reevaluated. This study aimed to estimate the degree of proliferating, differentiating and apoptotic activities of odontogenic cyst epithelium using antisera of PCNA, Ki-67, MPM-2, transglutaminase C, heat shock protein 70 and $ApopTag$^{(R)}$. method in 19 cases of odontogenic cysts. Cellular changes of the cyst epithelium were measured by intensity of each immunohistochemical staining. Results were as follows: 1. The proliferating activity of the cyst epithelium was slightly lower than that of normal oral mucosal epithelium, with the use of primary antibodies against PCNA, Ki-67, and MPM-2. And the proliferating activity of the epithelium in OKC group was even higher than that of the epithelium in non-OKC group. 2. The odontogenic cysts showed weakly positive reaction with transglutaminase C, but strongly positive reaction with HSP 70. 3. Occasionally, only a few apoptotic cell was observed in the superficial keratin layer of OKC. 4. The hyperplastic cyst epithelium infiltrated with mild inflammatory cells showed diffusely positive reaction with different proliferating factors. From the above results, we presumed that the endogenous proliferating and differentiating activity of the cyst epithelium was slightly lower than that of normal oral mucosal epithelium, and also supposed that the cyst epithelium could be reactivated for the further proliferation by the exogenous factors, such as inflammatory reaction and any chemicophysical irritations.

• Asian Pacific Journal of Cancer Prevention
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• 제15권5호
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• pp.2061-2067
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• 2014

Background: It has been demonstrated that neutrophil:lymphocyte (NLR) and platelet:lymphocyte (PLR) ratios are associated with prognosis in cancer patients. The aim of this study was to investigate whether pretreatment white blood cell (WBC), neutrophil, lymphocyte, monocyte, platelet, basophil and eosinophil counts, LDH level, NLR and PLR are associated with prognosis in patients with malignant pleural mesothelioma (MPM). Materials and Methods: We retrospectively reviewed files of 50 patients who were managed with a diagnosis of MPM between 2005 and 2010. Demographic and clinical characteristics, treatments, response to treatment and prognostic factors were evaluated, along with relationships between pretreatment blood parameters and prognosis. Results: Overall, 38 men and 12 women were included to the study. Mean age was $61.5{\pm}9.4$ years (range: 39-83 years). There was advanced disease in 86% (n=43) and the histological type was epithelial mesothelioma in the majority (82%). Of the cases, 17 (34%) received radiotherapy, while 42 cases underwent first- and second-line chemotherapy, with cisplatin plus pemetrexed as the most commonly used regimen. In the assessment after therapy, it was found that there was complete response in 4 cases (8%), partial response in 10 cases (20%), stable disease in 17 cases (34%) and progression in 19 cases (38%). Median follow-up was 10 months (range: 10 day-30 months). Median overall survival was found to be 20.7 months while median progression-free survival as 10 months. In univariate and multivariate analyses, it was found that factors significantly affecting overall survival included stage (p=0.030), response to treatment (p=0.026) and monocyte count (p=0.004), while factors affecting disease-free survival included NLR (p=0.018), response to treatment (p=0.001), and PLR score (p=0.003). Conclusions: Overall and disease-free survival was found to be better in cases with a WBC count<8.000, platelet count<300,000, and low NLR and PLR scores in malignant pleural mesothelioma.

• 방송공학회논문지
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• 제16권3호
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• pp.416-426
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• 2011

본 논문은 H.264/AVC의 인트라(Intra) 부호화에서 인트라 예측 모드를 병합하여 부호화 성능을 높일 수 있는 기술에 관한 것이다. 제안하는 기술은 기존의 인트라 부호화에서 예측 모드를 시그널링(Signaling) 하는 방법과 다르게 여러 블록의 예측 모드를 병합하는 방법을 사용하여 예측 모드를 시그널링 한다. 기설정한 경계값 이상의 블록이 주변 블록으로부터 예측된 모드와 같을 경우에는 제안된 방법을, 그렇지 않을 경우에는 기존의 방법을 사용하여 시그널링 하여 인트라 예측 모드 비트량을 줄임으로써 부호화 효율을 높이는 방법을 제안하였다. 실험 결과, 제안한 방법은 기존의 방법과 비교하여 약 0.05dB의 PSNR(Peak signal to-noise ratio) 증가, 약 1%의 비트율이 감소하였다. 특히 low bit-rate일 경우, 약 0.1dB의 PSNR 증가, 약 1.7%의 비트율이 감소시킴으로써 low bit-rate에서 효과적임을 알 수 있다.