• Title/Summary/Keyword: MPCE

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Anti-obesity effects of an enzymatic extract of mandarin (Citrus unshiu) peel in 3T3-L1 adipocytes (감귤피 효소적 추출물의 지방세포에서의 항비만 효과)

  • Jang, Yebin;Kang, Heejoo;Kim, Jusang;Lee, Seung-Hong
    • Korean Journal of Food Science and Technology
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    • v.53 no.2
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    • pp.149-153
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    • 2021
  • Mandarin peel (MP) is a by-product of the processing of citrus juice or other products. This study aimed to investigate the potential anti-obesity effect of an enzymatic extract of MP on the inhibition of adipogenesis in 3T3-L1 adipocytes. The enzymatic extract (MPCE) was prepared using the commercial food-grade carbohydrase Celluclast. Lipid accumulation and triglyceride levels were significantly lower in MPCE-treated cells than in untreated cells. In addition, MPCE treatment reduced the protein expression levels of peroxisome proliferator-activated receptor-γ, CCAAT/enhancer-binding protein α, sterol regulatory element-binding protein 1, and fatty acid-binding protein 4. These results suggest that MPCE inhibits adipogenesis by downregulating the expression levels of adipogenesis-related proteins. Therefore, the current findings demonstrate that MPCE possesses potent anti-obesity properties and could be a potential ingredient in functional food industries.

Property Evaluation of Breathable Blend Fabric of MPCE Copolymer and Wet Coagulated Polyurethane (MPCE copolymer와 습식 폴리우레탄의 블렌드에 의한 투습방수 나일론 직물의 제반 물성변화에 관한 연구)

  • Yi, Jong-Woo;Chae, Ei-Jung;Bae, Jin-Seok
    • Textile Coloration and Finishing
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    • v.26 no.4
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    • pp.322-330
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    • 2014
  • The phospholipid-based MPCE(2-Methacryloxyethyl Phosphoryl Chlorine) copolymer was mixed with wet polyurethane for coating of nylon fabrics. The substitution rate of water in coagulation bath with DMF was changed under control of the size of formed hydrophilic microporous cell enable to manufacture excellent breathable, anti-bacterial and moisture control fabrics. Biocompatible property, vapor permeability, hydrostatic pressure, moisture management and anti-bacterial property were investigated for treated nylon fabrics. In result, increased moisture transmission rates, decreased water resistance and outstanding moisture control property could be confirmed by enhanced hydrophilicity of wet-coated nylon fabric with MPCE copolymer.

Synthesis of New Phospholipid Biocompatible Textile Finishing Agent

  • Ko, Yong-Il;Yi, Jong-Woo;Kim, Sung-Hoon;Bae, Jin-Seok
    • Textile Coloration and Finishing
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    • v.22 no.4
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    • pp.293-299
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    • 2010
  • A methacrylate monomer having phospholipid polar group and cell membrane structure is known as highly biocompatible. Based on these properties, new biocompatible multi-functional textile finishing agent was developed using phospolipid copolymer. 2-Methacryloyloxyethyl phosphorylcholine (MPCE) was synthesized using 2-hydroxyethyl methacrylate (HEMA), 2-chloro-2-oxo-1,3,2-dioxaphospholane (COP) and triethylamine (TEA), and then polymerized to prepare MPCE copolymer by radical polymerization using azobisisobutyronitrile(AIBN). The structures of MPCE was characterized by FT-IR and 1H NMR and will be evaluated as textile finishing agent in further study.

Skin care effect of phospholipids type finishing agent treated textiles (Phospholipids type agent로 처리된 섬유의 스킨케어 효과)

  • Park, Joon-Bae;Lee, Jong-Woo;Bae, Jin-Seok
    • Proceedings of the Korean Society of Dyers and Finishers Conference
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    • 2011.11a
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    • pp.8-8
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    • 2011
  • Environmental technology (ET)는 이미 세계적으로 가장 중요한 기술로 주목받고 있으며 친환경적이고 생체적합한 상품에 대한 수요가 계속해서 증가하고 있다. 섬유시장에서도, 항균성, 피부노화 방지, 아토피 방지, 보습제와 같이 수많은 다기능성 친환경 제품들이 계속해서 개발되고 소개되어지고 있다. 특히, 피부 보호를 위한 생체적합 보습 가공제로 쓰이는 squalene, collage, chitosan, hyaluronic acid과 같은 물질들은 cosmetics, medical 시장에서 널리 쓰이고 있다. 그러나 섬유시장에서의 이러한 물질들은 섬유에 적용시켰을 때 만족스럽지 못한 기능으로 인해 그리 좋지 않은 평가를 받고 있다. 천연소재를 이용해 스킨케어 제품 제조 시 지속적인 안정성의 문제와 제품의 기능성, 내구성이 만족스럽지 못한 결과를 보인다. 이러한 문제를 해결하고자 binder처리를 시도하였지만 가공제의 스스로의 기능이 현저하게 저하되는 문제로 인해 널리 쓰이진 않았다. 또한 안정성을 증진시키고자 마이크로캡슐을 개발하였지만 섬유의 터치감이 거칠어지고 가격적인 면에서 만족스럽지 못한 문제점이 있다. 본 연구에서는 새로운 phospholipid 화합물 2-methacryloyl oxyethyl phosphoryl choline (MPCE)를 이용하여 polyester에 적용시킨 후 다양한 조건들을 살펴보았다. MPCE처리가 된 섬유는 흡습성, 대전방지성, 항균성, 피부자극이 없는 것과 같은 생체적합한 기능을 보여주었다.

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Synthesis of New Biocompatible Multi-Functional Textile Finishing Agent

  • Ko, Young-Il;Jung, Chul-Won;Kim, Sung-Hoon;Bae, Jin-Seok
    • Proceedings of the Korean Society of Dyers and Finishers Conference
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    • 2009.03a
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    • pp.160-161
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    • 2009
  • A methacrylate monomer having phospholipid polar group and cell membrane structure is known as highly biocompatible. Based on these properties, new biocompatible multi-functional textile finishing agent was developed using phospolipid copolymer. 2-Methacryloyloxyethyl phosphorylcholine (MPC) was synthesized using 2-hydroxyethyl methacrylate (HEMA), 2-chloro-2-oxo-1,3,2-dioxaphospholane (COP), trimethylamine (TMA) and triethylamine (TEA), and then polymerized to prepare MPC copolymer by radical polymerization using AIBN. The structures of MPC and MPCE were characterized by FTIR and 1H NMR and will be evaluated as textile finishing agent in further study.

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