• 제목/요약/키워드: MOR

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고성능 하이브리드 섬유 보강 콘크리트의 휨 및 유동 특성 (Flexural and Workable Properties of High Performance Hybrid Fiber Reinforced Concrete)

  • 박춘근;노명현;박대효
    • 콘크리트학회논문집
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    • 제17권4호
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    • pp.543-550
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    • 2005
  • 본 연구에서는 마이크로 섬유인 탄소섬유와 매크로 섬유인 강섬유가 서로 하이브리드 형태로 결합되고 미세한 광물 혼화재인 실리카퓸이 치환된 고성능 하이브리드 섬유보강 콘크리트(HPHFRC)의 파괴계수(MOR), 휨인성 특성($I_30$$W_{2.0}$), 유동성(슬럼프)이 분산분석(ANOVA)을 통해 특성화된다. MOR I30(또는 $W_{2.0}$), 슬럼프 데이터들은 휨 성능과 유동성을 평가하기 위한 특성치로 사용된다. 특히, 실험회수를 줄이기 위하여 일부실시 직교배열에 따라 실험이 계획된다. 각 특성인자를 각 실험인자에 대해서 평가한 결과, 강섬유는 MOR 과 $I_{30}$의 특성인자 측면에서 상당히 유의한 실험인자로 나타난다. 또한 분산분석 결과, 실험인자의 유의도에 따라 다음과 같은 평가가 이용될 수 있다 유동성(슬럼프) 감소는 실리카 흄, 강섬유, 탄소섬유 실험인자 순서로 유의하게 나타난다. MOR 향상은 실리카퓸($\fallingdotseq$ 탄소섬유), 강섬유 실험인자 순서로 유의한 것으로 나타난다. 휨인성 증진은 실리카퓸, 탄소섬유, 강섬유 실험인자 순서로 유의하게 나타난다. 실험범위 내에서 강섬유 $1.0\%$, 탄소섬유 $0.25\%$, 실리카퓸 $5.0\%$의 조합이 각 특성치들을 가장 우수하게 향상시키고 유동성이 확보된 실험 조건으로 도출된다.

A Multicenter Matched Case Control Study of Breast Cancer Risk Factors among Women in Karachi, Pakistan

  • Shamsi, Uzma;Khan, Shaista;Usman, Sheheryar;Soomro, Saleem;Azam, Iqbal
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권1호
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    • pp.183-188
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    • 2013
  • Background: Breast cancer (BC), the most common female cancer in Pakistan, is associated with a very high mortality. However, the roles of individual risk factors for BC among Pakistani women are still controversial. To assess potential risk factors for BC, a matched case-control study was conducted in two tertiary care hospitals of Karachi, Pakistan. Materials and Methods: The study population included 297 pathologically confirmed incident cases of BC patients diagnosed between January 2009 and December 2010. 586 controls without any history of BC were matched on hospital and ${\pm}5$ years of ages. Results: Positive family history of BC (MOR=1.72; 95%CI: 1.10, 2.80 for first degree vs. none), single marital status (MOR=1.55; 95%CI: 1.10, 2.39 for single/divorced/widowed women vs. married women), older age at menopause (MOR=3.92; 95%CI: 2.52, 6.18 for menopausal women aged below 45 years, MOR=6.42; 95%CI: 3.47, 11.98 for menopausal women above 45 years of age compared with premenopausal women) conferred an increased risk of BC for women. Increasing parity decreased the risk of BC (MOR=0.90; 95%CI: 0.85, 0.97 for each live birth). Intake of Vitamin D supplements (MOR=0.30; 95%CI: 0.12, 0.81 for ${\leq}3$ years and MOR=0.27; 95%CI: 0.13, 0.56 for >3 years) was protective compared to non-users of Vitamin D. Conclusions: This study confirmed only few of the recognized risk factors in Pakistani women. The protective effect of Vitamin D is important from public health perspective and needs to be further explored through a randomized controlled trial.

The Effect of Morphine on REST Expression in Human Neuroblastoma NMB Cells

  • Kim, Do-Kyung;Kim, Chun-Sung;Kim, Heung-Joong;Kook, Joong-Ki;Kim, Seung-Hee;Lee, Baek-Hee;Lee, Yun-Ho;Mo, Shin-Yeob;Loh, Horace H.
    • International Journal of Oral Biology
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    • 제35권2호
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    • pp.69-74
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    • 2010
  • The mu opioid receptor (MOR) has been regarded as the main site of interaction with analgesics in major clinical use, particularly morphine. The repressor element-1 silencing transcription factor (REST) functions as a transcriptional repressor of neuronal genes in non-neuronal cells. However, it is expressed in certain mature neurons, suggesting that it may have complex and novel roles. In addition, the interactions between MOR and REST and their functions remain unclear. In this study, we examined the effects of morphine on the expression of REST mRNA and protein in human neuroblastoma NMB cells to investigate the roles of REST induced by MOR activation in neuronal cells. To determine the effects of morphine on REST expression, we performed RT-PCR, real-time quantitative RT-PCR, western blot analysis and radioligand binding assays in NMB cells. By RTPCR and real-time quantitative RT-PCR, the expression of REST was found to be unchanged by either the MOR agonist morphine or the MOR specific antagonist CTOP. By western blot, morphine was shown to significantly inhibit the expression of REST, but this suppression was completely blocked by treatment with CTOP. In the radioligand binding assay, the overexpression of REST led to an increased opioid ligand binding activity of endogenous MOR in the NMB cells. These results together suggest that morphine inhibits the expression of REST in human neuroblastoma cells through a post-transcriptional regulatory mechanism mediated through MOR.

Dimensional Stability and Bending Properties of Small Diameter Log Treated by Sap-displacement Method

  • Lee, Jun-Jae;Koo, Ja-Il;Chun, Su-Kyoung
    • Journal of the Korean Wood Science and Technology
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    • 제28권4호
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    • pp.61-71
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    • 2000
  • The effect of the treatment with CCFZ, FR-4, and PEG400 from butt end on the dimensional stability and bending properties was examined. Three softwood species such as red pine, Korean white pine and Japanese larch and three hardwood species such as poplar, alder and oak were investigated in this research. Shrinkage of red pine, Korean white pine, poplar, and alder treated with PEG400 decreased. However, there was no significant decrease of shrinkage in Japanese larch and oak. The decrease of shrinkage when moisture content changed from about 20% to 10% was larger than that at any other phase. In regard to the effect of treatment on bending properties, bending MOE and MOR of all specimens treated with PEG400 decreased significantly. Especially in the case of red pine, poplar, and alder treated with PEG400, bending MOR reduced 9%, 14%, and 12%, respectively. Reductions of MOR of the hardwood was also much larger than that of the softwood. However, in all species, treatment with CCFZ and FR-4 did not affect the change of bending MOE and MOR significantly. Comparing the large specimen which also included heartwood with the small specimen which included only treated sapwood, there was a difference in the change of bending MOE and MOR between them. The large specimens of Korean white pine, alder and Poplar, which had a relatively low proportion of sapwood(18~22%), showed the decrease of MOR by 11~13% more than that of small specimens, while red pine, Japanese larch and oak, which had a relatively high proportion of sapwood(35~40%), showed little decrease. It means that bending MOE and MOR of structural wood treated from butt end should be considered in terms of sapwood proportion as well as effect of treated chemicals.

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Comparison of Circuit Reduction Techniques for Power Network Noise Analysis

  • Kim, Jin-Wook;Kim, Young-Hwan
    • JSTS:Journal of Semiconductor Technology and Science
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    • 제9권4호
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    • pp.216-224
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    • 2009
  • The endless scaling down of the semiconductor process made the impact of the power network noise on the performance of the state-of-the-art chip a serious design problem. This paper compares the performances of two popular circuit reduction approaches used to improve the efficiency of power network noise analysis: moment matching-based model order reduction (MOR) and node elimination-based MOR. As the benchmarks, we chose PRIMA and R2Power as the matching-based MOR and the node elimination-based MOR. Experimental results indicate that the accuracy, efficiency, and memory requirement of both methods very strongly depend on the structure of the given circuit, i.e., numbers of the nodes and sources, and the number of moments to preserve for PRIMA. PRIMA has higher accuracy in general, while the error of R2Power is also in the acceptable range. On the other hand, PRIMA has the higher efficiency than R2Power, only when the numbers of nodes and sources are small enough. Otherwise, R2Power clearly outperforms PRIMA in efficiency. In the memory requirement, the memory size of PRIMA increases very quickly as the numbers of nodes, sources, and preserved moments increase.

Nondestructive Bending Strength Evaluation of Ceramics Made from Miscanthus sinensis var. purpurascens Particle Boards - Effect of Resin Impregnation Ratio -

  • Byeon, Hee-Seop;Won, Kyung-Rok;Oh, Seung-Won
    • Journal of the Korean Wood Science and Technology
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    • 제42권2호
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    • pp.130-137
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    • 2014
  • Nondestructive evaluation (NDE) method by using a resonance frequency mode was carried out for ceramics made from particle boards with different phenol resin impregnation ratios (30, 40, 50, 60%) at carbonizing temperature of $800^{\circ}C$. The material for ceramics was Miscanthus sinensis var. purpurascens board. Dynamic modulus of elasticity increased with increasing impregnation ratio. There was a close relationship of dynamic modulus of elasticity and static bending modulus of elasticity to modulus of rupture (MOR). However, the result indicated that correlation coefficient is higher in dynamic modulus of elasticity to MOR than that in static modulus of elasticity to MOR. Therefore, the dynamic modulus of elasticity using resonance frequency by free vibration mode is more useful as a nondestructive evaluation method for predicting the MOR of ceramics made from Miscanthus sinensis var. purpurascens particle boards by different phenol resin impregnation ratios.

Differential actions of intracerebroventricular (ICV) opioid receptor agonists on the activity of dorsal horn neurons (DHN) in the cat spinal cord

  • 오우택;문태상;하태길;고광호
    • 한국응용약물학회:학술대회논문집
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    • 한국응용약물학회 1994년도 춘계학술대회 and 제3회 신약개발 연구발표회
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    • pp.303-303
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    • 1994
  • ICV infusion of morphine (MOR) produces strong analgesia in man and animals. The analgesic effect is thought to be mediated by the centrifugal inhibtory control, But neural mechanisms of the analgesic effect of ICV morphine are not well understood. For example, in the previous studies, ICV morphine does not inhibit nociceptive transmission in the spinal cord. On the contrary, ICV MOR often excites activity of dorsal horn neuron in the spinal cord. In the present study, we found that ICV MOR had dust actions on activity of dorsal horn neuron that it produced both inhibition and excitation of dorsal horn neurons. Since MOR exerts i Is action via three different types of opioid receptors, we further sought to investigate if there are differential effects of opioid receptor agonists on dorsal horn neurons when administered ICV.

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Nondestructive Bending Strength Evaluation of Woodceramics Made from Woody Part of Broussonetia Kazinoki Sieb. - Effect of Resin Impregnation Ratio -

  • Byeon, Hee-Seop;Kim, Jae-Min;Won, Kyung-Rok;Oh, Seung-Won
    • Journal of the Korean Wood Science and Technology
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    • 제39권5호
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    • pp.398-405
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    • 2011
  • Nondestructive evaluation (NDE) technique method using a resonance frequency mode was carried out for woodceramics made by different phenol resin impregnation ratios (40, 50, 60, 70%) for Broussonetia Kazinoki Sieb. Dynamic modulus of elasticity increased with increasing resin impregnation ratios. There was a close relationship between dynamic modulus of elasticity and static bending modulus of elasticity and between dynamic modulus of elasticity and MOR and between static bending modulus of elasticity and MOR. Therefore, the dynamic modulus of elasticity using resonance frequency mode is useful as a nondestructive evaluation method for predicting the MOR of woodceramics made by different impregnation ratios.

손가락결합부재에 대한 초음파 비파괴시험에서 센서 위치의 영향 (Effects of Transducer Position in Ultrasonics Nondestructive Tests of Finger-Jointed Lumber)

  • 장상식
    • Journal of the Korean Wood Science and Technology
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    • 제26권1호
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    • pp.1-6
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    • 1998
  • 손가락결합부재에 대한 정적휨시험 및 초음파 비파괴시험을 실시하였다. 발신 및 수신 변환기의 상대 위치와 두 변환기 사이의 거리에 따른 음전달속도의 변화를 분석하였으며 정적 휨시험으로 부터 구한 MOE 및 MOR과 비교하였다. MOR과 음전달속도는 손가락의 경사가 증가할수록 감소하였다. MOR은 음전달속도와 매우 밀접한 상관관계를 보였으나 MOE는 손가락의 경사도나 음전달속도에 큰 영향을 받지 않는 것으로 나타났다. 음전달속도는 섬유방향이 방사방향이나 접선방향에 비하여 더 높은 값을 나타내었다. 발신 및 수선 변환기를 동일면에 부착한 경우에 직각면 또는 반대면에 부착한 경우보다 더 높은 음전달속도를 나타내었다. 변환기 사이의 거리가 증가할수록 음전달속도는 양끝면에 변환기를 부착한 경우의 속도에 수렴하는 경향을 나타내었다.

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티타늄 및 구리증착이 알루미나 곡강도에 미치는 영향 (The Effect of Titanium and Copper Coatings on the Modulus of Rupture of Alumina)

  • 황하룡;이임렬
    • 한국표면공학회지
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    • 제27권1호
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    • pp.29-35
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    • 1994
  • The effects of coating of 3$\mu\textrm{m}$ thickness on the mechanical property of alumina after heat treatment at 100$0^{\circ}C$ for 30minutes under $10^{-6}$torr vacuum was quantified in terms of modulus of rupture(MOR) using Weibull plot. While the copper coating did not change MOR of alumina due to the nonwetting behavior of Cu on $Al_2O_3$, the reactive titanium metal coating caused a noticeable 29% reduction in averaged MOr strength. This was related with the combined effects of microcracks in coating formed during heat treatment and good bonding character between Ti and $Al_2O_3$. The effect of cosputtering of Ti and Cu, bilayer coatings of Cu/Ti and Ti/Cu were also investigated. It was found that Ti, cosputtered, Cu/ti and Ti/Cu coatings reduced MOR strength of alumina in the order listed. This was correlated with the amount of Ti at coating/alumina inter-face associated with a coated layer or segregation of Ti during heat treatment.

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