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Energy Efficient Wireless Data Transmission for Personal Health Devices

  • Kim, Sang-Kon;Kim, Tae-Kon;Koh, Jin-Hwan
    • Journal of Electrical Engineering and Technology
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    • v.8 no.6
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    • pp.1559-1570
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    • 2013
  • The family of ISO/IEEE11073 standards is the basis of the e-health system and provides interoperability for personal health devices. In the early stage of e-health business, it was expected that people would use a health device individually. In this case, a measurement datum was episodically acquired and generally transmitted for one person at a time. Recently, a health device is expected to be used by multiple people, and large amounts of measurement data are gathered in a short time interval. In addition, mobile health devices have become more popular, so that energy efficient measurement data transmission is required, to prolong the use of a device. In IEEE11073 PHD standards, data transmission is classified into three different types: immediate individual transfer, small block transfer, and large block transfer. The large block transfer using PM-store concept provides efficient transmission. However, an existing PM-store has problem when a device is used by multiple people. To address the defined problem, a modified PM-segment that is in compliance with 11073 standards is proposed in this paper. In particular, the proposed PM-segment is designed to minimize the additional complexity of an agent instead of a manager and it is interoperable with the existing manager. The proposed PM-segment shows better performance than the existing PM-segment, in terms of memory requirements and expected queue time. Also, performance comparison among the three transfers is performed in regard to the delay time and communication power consumption points of view.

Establishment of UPLC method for analysis of liquiritigenin and studies on the processing of licorice for enhancement of liquiritigenin content (감초 지표성분 분석법 확립 및 liquiritigenin의 함량 증대를 위한 감초의 수치에 관한 연구)

  • Lee, Jong-Rok;Jo, Mi-Jeong;Park, Sang-Mi;Kim, Sang-Chan;Park, Sook-Jahr
    • Herbal Formula Science
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    • v.18 no.1
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    • pp.145-154
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    • 2010
  • Objective : Licorice has been used for treating digestive disorder and also recommended as a detoxification agent. Liquiritigenin, a component of licorice, has been reported to have various biological activities. In this study, we aimed to establish the analytical method for liquiritigenin content in licorice and the processing method for the enhancement of liquiritigenin content in licorice. Methods : Processing was accomplished by roasting licorice at $250^{\circ}C$ for indicated time periods (5-20 min). Analysis of liquiritigrnin from roasted licorice was conducted using UPLC(Ultra Performance Liquid Chromatography). Results : We established UPLC method for the analysis of liquiritigenin using water : acetonitrile gradient as mobile phase. Furthermore, we standardized the processing condition of licorice to enhance liquiritigenin content using UPLC method. Processing of licorice was accomplished by roasting at $250^{\circ}C$ for indicated time periods (5-20 min) and by pretreating with 50% of acetic acid or 30% ethanol for 24 h. By roasting licorice, the liquiritigenin contents in the licorice were increased. The best roasting time of licorice was 6 min, while roasting for the time above 8 min resulted in diminishing liquiritigenin contents. Moreover, pretreatment with 50% of acetic acid or 30% ethanol picked up liquiritigenin contents in roasted licorice. Conclusion : The adequate processing condition of licorice for the enhancement of liquiritigenin contents was obtained by pretreating licorice with 50% of acetic acid or 30% ethanol for 24 h and then by roasting at $250^{\circ}C$ for 6 min.

Determination of diphencyprone and its photo-degradation product incompounded preparations using HPLC

  • Cho, Chong Woon;Kim, Kyung Tae;Park, Miyeon;Kim, Jin Seog;Lee, Jinbok;Kang, Jong Seong
    • Analytical Science and Technology
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    • v.31 no.5
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    • pp.179-184
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    • 2018
  • Diphencyprone (DPCP) is frequently used as a compounded preparation in dermatology for the treatment of alopecia and recalcitrant warts based on the immune reaction of skin allergy. However, DPCP is a non-recognized agent in Pharmacopoeia, because there are no criteria or analytical method for quality control of its powder and formulation. DPCP is unstable under light irradiation because as it easily decomposes to diphenylacetylene (DPA). This study aims to develop a simultaneous HPLC analytical method for analyzing DPCP and DPA in the raw materials and compounded preparation. The method required a C18 column ($250{\times}4.6mm$, $5{\mu}m$) at $40^{\circ}C$ with a mobile phase of (A) 0.01 M phosphoric acid in water and (B) acetonitrile at UV 220 nm. DPA conversion to DPCP in the powder and compounded preparations was accelerated after light exposure for 60 min. In addition, this resulted in different patterns depending on the wavelength of light and the formulation. That is, DPCP in compounded preparation was more unstable than that in the powder. However, the DPCP formulation in amber bottles was observed to remain stable, although the measured concentrations of DPCP were somewhat different from the nominal concentration of the compounded preparations. The control of the exact concentration is required for effective disease treatment, depending on the state of the patient. In conclusion, these results will be useful for the recognition of DPCP in Pharmacopoeia and new DPCP formulation development to prevent photodecomposition.

Improved Route Search Method Through the Operation Process of the Genetic Algorithm (유전 알고리즘의 연산처리를 통한 개선된 경로 탐색 기법)

  • Ji, Hong-il;Moon, Seok-hwan
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2015.05a
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    • pp.632-635
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    • 2015
  • Proposal algorithm in this thesis introduced cells, units of router group, for distributed processing of previous genetic algorithm. This thesis presented ways to reduce search delay time of overall network through cell-based genetic algorithm. As a result of performance analysis comparing with existing genetic algorithm through experiments, the proposal algorithm was found superior in terms of costs and delay time. Furthermore, time for routing an alternative path was reduced in proposal algorithm, in case that a network was damaged in existing optimal path algorithm, Dijkstra algorithm, and the proposal algorithm was designed to route an alternative path faster than Dijkstra algorithm, as it has a 2nd shortest path in cells of the damaged network. The study showed that the proposal algorithm can support routing of alternative path, if Dijkstra algorithm is damaged in a network.

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Protein Binding of [S]-Perillyl Alcohol in HSA using High-Performance Frontal Analysis (HPFA를 이용한 HSA와 [S]-Perillyl Acohol의 단백질 결합력)

  • 송명석;왕덕선;구윤모;노경호
    • KSBB Journal
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    • v.18 no.2
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    • pp.100-106
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    • 2003
  • An on-line frontal analysis HPLC system was developed to determine the unbound concentration of (S)-perillyl alcohol, an potential anti-cancer agent, in human serum albumin (HSA) solution, The analysis was performed on a Develosil 100 Diol 5 (10 cm x 4.6 mm I.D.) high-performance frontal analysis (HPFA) column. Sodium phosphate solution was used as the mobile phase (pH 7.4, ionic strength 0.17) at a flow rate of 1 $m\ell$/min. UV wavelength was set at 205 nm. A injection volume of 600${mu}ell$ was chosen to ensure the compound eluted formed a zonal peak with a plateau. By Scatchard analysis, it was found that the binding constant(K) and binding number(n) of (S)-perillyl alcohol to molecular HSA were 2.05 x $10^6$ [$M{-1}$], 0.00428, respectively.

Quantification Analysis and Antioxidant Activity of Leejung-tang (LC-MS/MS를 이용한 이중탕(理中湯)의 정량분석 및 항산화 활성)

  • Seo, Chang-Seob;Kim, Ohn Soon;Kim, Yeji;Shin, Hyeun-Kyoo
    • Herbal Formula Science
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    • v.21 no.1
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    • pp.177-185
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    • 2013
  • Objectives : Leejung-tang (Lizhong-tang) has been used for treatment of gastrointestinal disorders in Korea. In this study, we performed quantification analysis of five marker components, liquiritin, ginsenoside Rb1, ginsenoside Rg1, glycyrrhizin, and 6-gingerol in Leejung-tang using a ultra performance liquid chromatography- electrospray ionization-mass spectrometer (UPLC-ESI-MS). In addition, we evaluated antioxidant activity of Leejung- tang. Methods : The column for separation of five constituents used a UPLC BEH C18 ($100{\times}2.1mm$, $1.7{\mu}m$) maintained at $45^{\circ}C$. The mobile phase consisted of two solvent systems, 0.1% (v/v) formic acid in H2O (A) and CH3CN (B) by gradient flow. The flow rate was 0.3 mL/min with detection at mass spectrometer. The antioxidative activities conduct an experiment on 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 2,2-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activities of Leejung-tang. Results : Calibration curves of five marker compounds were acquired with r2 values > 0.99. The amount of the five compounds in Leejung-tang were 0.07 - 0.84 mg/g. The concentration required for 50% reduction (RC50) against ABTS radical was 119.02 ug/mL. In addition, the scavenging against DPPH radical of Leejung-tang was 11.4%, 14.5%, 19.8%, 29.6%, and 49.2% at 25 ug/mL, $50{\mu}g/mL$, $100{\mu}g/mL$, $200{\mu}g/mL$, and $400{\mu}g/mL$, respectively. Conclusions : The established LC-MS/MS method will be helpful to improve quality control of Leejung-tang. In addition, Leejung-tang is a potential antioxidant therapeutic agent.

An SMS Notarization System Using Smartphones (스마트폰을 활용한 SMS 공증 시스템)

  • Lee, Yunho
    • Journal of Internet Computing and Services
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    • v.19 no.5
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    • pp.13-19
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    • 2018
  • Although it's been nearly decade since the electronic notarization system enforced, the utilization is not high because of the troublesomeness of the client or his agent to visit the notarial office directly. Recently, the ministry of justice introduced e-notary based on audio-visual conference through amendament of the notarial law, and hence it will vitalize the usage of e-notary. In addition, due to the spread of smartphones, many people use SMS messages to express simple statements or promises. However, in case of legal disputes, the judgment of the court is different according to the case. The electronic notarization system can be used to prove of evidence of SMS messages, however, there is a hassle to convert SMS messages to electronic documents. To solve this problem, this paper proposes an SMS notarization system using smartphones. The proposed system uses reliable notarization server and it is divided into notarization system for message senders and notarization system for message receivers according to notary requestor.

Proposal of Personalized Recommendation for Korean Food and Tour Using Beacon System (비콘을 활용한 개인 맞춤형 한식과 관광지 추천 관리 시스템 제안)

  • Sung, Kihyuk;Ryu, Gihwan;Yun, Daiyeol
    • The Journal of the Convergence on Culture Technology
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    • v.6 no.3
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    • pp.267-273
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    • 2020
  • Beacon is a wireless communication device that can automatically recognize the smart device in the short distance and transmit the necessary data, Beacon is a representative Internet of Things (IoT) facility in the era of the 4th Industrial Revolution, which is utilized in various fields such as short-distance information delivery, mobile location service, shopping, and marketing, and is constantly evolving. In this paper, it is based on tourist site-based recommendation information service. A system is proposed that recommends customized information according to the user's interest, preference, etc. by incorporating beacon technology. In other words, it acts as an information agent that informs tourists of desired information. In order to meet the needs of tourists, it is necessary to build an intelligent tourism recommendation system. The personalized Korean food and tourism recommendation management system using the beacon technology proposed in this paper is expected to provide high-quality services not only to foreigners visiting Korea but also to Korean tourists.

Study on the Next Disaster Safety Communication Network in M2M Communication (사물지능통신을 이용한 차세대 재난안전통신망에 관한 연구)

  • Kang, Heau-Jo
    • Journal of Advanced Navigation Technology
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    • v.15 no.4
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    • pp.585-590
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    • 2011
  • In the past few years, M2M (Machine-to-Machine) applications have become a hot topic in the wireless industry. While M2M applications can be used for many purposes (smart homes, smart metering/electricity meter reading, fleet management, mobile workforce, automobile insurance, vending machines, etc), and in many sectors (healthcare, agriculture, commercial, industrial, retail, utility, etc.), smart metering applications or smart grids present the biggest growth potential in the M2M market today. M2M platform is the future ubiquitous network technologies which provide the integrated service with the networks and devices. The promising technologies to tackle these problems are the Semantic technologies, for interoperability, and the Agent technologies for management of complex systems. In this paper the information communication technique based on the disaster prevention system's for the M2M, concepts and its requirement technology and application are studied.

Numerical Study on the Injector Shape and Location of Urea-SCR System of Heavy-duty Diesel Engine for Preventing $NH_3$ Slip (대형 디젤엔진용 SCR 시스템의 암모니아 슬립 억제를 위한 인젝터의 형상 및 위치에 관한 수치적 연구)

  • Jeong Soo-Jin;Lee Sang Jin;Kim Woo-Seung;Lee Chun Beom
    • Transactions of the Korean Society of Automotive Engineers
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    • v.14 no.1
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    • pp.68-78
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    • 2006
  • In the past few years, considerable efforts have been directed towards the further development of Urea-SCR(selective catalytic reduction) technique for diesel-driven vehicle. Although urea possesses considerable advantages over Ammonia$(NH_3)$ in terms of toxicity and handling, its necessary decomposition into Ammonia and carbon dioxide complicates the DeNOx process. Moreover, a mobile SCR system has only a short distance between engine exhaust and the catalyst entrance. Hence, this leads to not enough residence times of urea, and therefore evaporation and thermolysis cannot be completed at the catalyst entrance. This may cause high secondary emissions of Ammonia and isocyanic acid from the reducing agent and also leads to the fact that a considerable section of the catalyst may be misused for the purely thermal steps of water evaporation and thermolysis of urea. Hence the key factor to implementation of SCR technology on automobile is fast thermolysis, good mixing of Ammonia and gas, and reducing Ammonia slip. In this context, this study performs three-dimensional numerical simulation of urea injection of heavy-duty diesel engine under various injection pressure, injector locations and number of injector hole. This study employs Eulerian-Lagrangian approach to consider break-up, evaporation and heat and mass-transfer between droplet and exhaust gas with considering thermolysis and the turbulence dispersion effect of droplet. The SCR-monolith brick has been treated as porous medium. The effect of location and number of hole of urea injector on the uniformity of Ammonia concentration distribution and the amount of water at the entrance of SCR-monolith has been examined in detail under various injection pressures. The present results show useful guidelines for the optimum design of urea injector for reducing Ammonia slip and improving DeNOx performance.