• 제목/요약/키워드: MN Test

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Mutagenicity Study of (R)-JG-381, A New Antidiabetic Agent (항당뇨물질 (R)-JG-381의 변이원성 시험)

  • 오우용;주상섭;박형근;함광수;조장섭;이선미
    • Biomolecules & Therapeutics
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    • v.8 no.3
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    • pp.248-254
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    • 2000
  • (R)-JG-381, a R form of alkylglycidic acid derivative, was examined for mutagenicity in the reverse mutation test on bacteria, chromosomal aberration test on cultured mammalian cells and micronucleus test in mice. In the reverse mutation test on bacteria using Salmonella typhimurium strain TA98, TA100, TA102, TA1535, TA1537 with or without a metabolic activation system (S9 mix), (R)-JG-381 did not affect the revertant colonies but significantly increased revertant colonies in one test strain, TA98, compared with the vehicle control. In the chromosomal aberration (CA) test using cultured Chinese Hamster Lung fibroblast(CHL) cells, the number of aberrant cells was clot increased in the presence or absence of 59 mix at concentration of the (R)-JG-381 0.025 $\mu$l/m1 to 0.1 $\mu$l/m1, compared with vehicle control. In the micronucleus (MN) test, micronucleated polychromatic erythrocytes in the (R)-JG-381-treated mice were not different from those of the vehicle-treated mice.

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Evaluation on Potentiostatic Characteristics of Al-4.06Mg-0.74Mn Alloy with Cavitation Environment in Seawater (Al-4.06Mg-0.74Mn 합금의 해수 내 캐비테이션 환경에 따른 정전위 특성 평가)

  • Lee, Seung-Jun;Han, Min-Su;Jang, Seok-Ki;Kim, Seong-Jong
    • Journal of the Korean institute of surface engineering
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    • v.45 no.6
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    • pp.272-277
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    • 2012
  • The hull of a fast sailing aluminium ship are generally prone to erosion owing to the impact of seawater. At this time, synergistic effects of the erosion and the corrosion by aggressive ions such as chlorides tend to aggravate the damage. There have been various attempts, including selection of erosion-resistant materials, cathodic protection and addition of corrosion inhibitors, to overcome damage by erosion or corrosion under marine environments. These approaches, however, have limits on identifying the damage mechanism clearly, because they depend on analogical interpretation by correlating two damage behaviors after the individual studies are assessed. In this research, it was devised a hybrid testing apparatus that integrates electrochemical corrosion test and cavitation test, and thus the erosion-corrosion behavior by cavitation was investigated more reliably. As a result, the slightest damage was observed at the potentials between -1.6 V and -1.5 V. This is considered to be due to a reflection or counterbalancing effect caused by collision of the cavitation cavities and the hydrogen gas formed by activation polarization.

Empirical Relationship Between SP-curves and Tensile Properties in Mn-Mo-Ni Low Alloy Steels (Mn-Mo-Ni 저합금강의 SP-곡선과 인장물성과의 실험적 관계)

  • Lee, Jae-Bong;Kim, Min-Chul;Park, Jai-Hak;Lee, Bong-Sang
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.28 no.5
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    • pp.554-562
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    • 2004
  • An empirical relationship between parameters from SP curves and tensile properties has been systematically investigated by experimental tests and FEM simulations. A series of SP and tensile tests were performed. SP tests were also simulated by FE analysis with various tensile properties. It was found that the yield loads(Py) and the maximum loads( $P_{MAX}$) in SP curves were linearly related with the yield strength($\sigma$$_{o}$) and the tensile strength($\sigma$$_{UTS}$), respectively. The yield loads defined from the intersection point of two lines tangent to the elastic bending region and plastic bending region showed better relation to the yield strength than those from offset line. The maximum loads in SP curves showing plastic instability region was linearly related with the tensile strengths. The slope of SP curves in simulation results had a close correlation with the hardening coefficient and hardening strength as well.l.l.l.

Development of High Strength Microalloyed Steel for Cold Forming by Controlled Rolling and Cooling Technology (제어압연${\cdot}$제어냉각기술을 이용한 고강도 냉간성형용 비조질강의 개발)

  • Kim N. G.;Park S. D.;Kim B. O.;Choi H. J.
    • Proceedings of the Korean Society for Technology of Plasticity Conference
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    • 2005.05a
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    • pp.321-324
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    • 2005
  • The main purpose of the present study has been placed on investigating the effects of controlled rolling and cooling on the microstructures and mechanical properties of C-Si-Mn-V steels for cold forming. The steels were manufactured in vacuum induction melting(VIM) furnace and casted to 1.1ton Ingots and the ingots were forged to $\Box150$ billet. The forged billets were reheated in walking beam furnace and rolled to coil, the stocks were rolled by Controlled Rolling and Cooling Technology (CRCT), so rolled at low temperature by water spraying applied in rolling stage and acceleratly cooled before coiling. Rolled coils were cold drawed to the degree of $27\%$ of area reduction without heat treatment. Microstructual observation, tensile test, compression test and charpy impact tests were conducted. The mechanical properties of the steels were changed by area reduction of cold drawing and it is founded that there are optimum level of cold drawing to minimize compression stress for these steels. From the result of this study, it is conformed that mechanical properties and microstructure of C-Si-Mn-V steels for cold forming were enhanced by accelerated cooling and founded optimum level of cold drawing.

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The Response time of the Hydrogen Peroxide Monopropellant Thruster as Different Catalysts (서로 다른 촉매를 사용하는 과산화수소 추력기의 응답 속도)

  • An, Sung-Yong;Kwon, Se-Jin
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2008.11a
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    • pp.371-374
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    • 2008
  • The performance of several catalysts to decompose the high test peroxide (HTP) was described in this paper. Manganese oxide, Platinum and Iridium were coated on the gamma alumina. The response time of various catalysts was measured with a 50 Newton class thruster. Ir/$Al_2O_3$ that showed the fastest response time at the thruster, failed the reaction when continuous mode test was carried out with the thruster. Pt/$Al_2O_3$ and MnO_2/Al_2O_3$ can be substitutes to decompose the HTP. In addition, for larger thruster, MnO_2/Al_2O_3$ can be a good catalyst because its cost is below 5 % of Pt/$Al_2O_3$.

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A Comprasion of the Activation of Mirror Neurons Induced by Action Observation between Simple and Complex Hand Movement

  • Lee, Mi Young;Kim, Ju Sang
    • The Journal of Korean Physical Therapy
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    • v.31 no.3
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    • pp.157-160
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    • 2019
  • Purpose: We compared the activation pattern of the mirror neurons (MN) between two types of hand movement according to action observation using functional MRI. Methods: Twelve right-handed healthy subjects (5 male and 7 female, mean age $21.92{\pm}2.02years$) participated in the experiment. During fMRI scanning, subjects underwent two different stimuli on the screen: 1) video clips showing repeated grasping and releasing of the ball via simple hand movement (SHM), and (2) video clips showing an actor performing a Purdue Pegboard test via complex hand movement (CHM). paired t-test in statistical parametric mapping (SPM) was used to compare the activation differences between the two types of hand movement. Results: CHM as compared with the SHM produced a higher blood oxygen level dependent (BOLD) signal response in the right superior frontal gyrus, left inferior and superior parietal lobules, and lingual gyrus. However, no greater BOLD signal response was found by SHM compared with CHM (FWE corrected, p<0.05). Conclusion: Our findings provided that the activation patterns for observation of SHM and CHM are different. CHM also elicited boarder or stronger activations in the brain, including inferior parietal lobule called the MN region.

A Case Study of High Capacity Bi-Directional High Pressure Pile Load Test (초고용량 양방향 말뚝재하시험(BDH PLT) 수행사례 분석)

  • Kim, Sang-Il;Lee, Min-Hee;Jeong, Sung-Min;Jeong, Eun-Taeg;Choi, Yong-Kyu
    • Proceedings of the Korean Geotechical Society Conference
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    • 2010.03a
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    • pp.1156-1163
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    • 2010
  • The bi-directional high pile load test(BDH PLT) does not have weaknesses found in the existing bi-directional low pile load test(BDL PLT); it has strong economics, is unbound by load capacity limit and secures quality stability of working piles. In this study, Verification the field found a very high capacity level of stability and reliability of the BDH PLT, as well as outstanding field applicability. Field verifications reaffirmed the advantage of the BDH PLT device, which was capable of loading 90 MN capacities as maximum. It was also found to be durable enough to load high capacity with ease.

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Adsorption Characteristics of Pb(II) by Manganese Oxide Coated Activated Carbon in Fixed Bed Column Study (망간산화물이 코팅된 활성탄의 납 흡착특성에 관한 칼럼 실험)

  • Lee, Myoungeun;Lee, Chaeyoung;Chung, Jaewoo
    • Journal of the Korean GEO-environmental Society
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    • v.15 no.8
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    • pp.39-44
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    • 2014
  • Effects of operating parameters on the breakthrough properties of Pb(II) by $Mn_3O_4$ coated activated carbon prepared by supercritical technique were investigated through fixed-bed column experiments. The mass transfer zone and equilibrium adsorption capacity were enhanced about 2.8 times for Pb(II) by $Mn_3O_4$ coating onto activated carbon. Increase of bed height enhanced the residence time of Pb(II) in adsorption zone, giving the higher breakthrough time, mass transfer zone and equilibrium adsorption capacity. Increase of flow rate reduced the residence time and diffusion of Pb(II) in adsorption zone, therefore decreased the equilibrium adsorption capacity. The higher inlet concentration of Pb(II) decreased the breakthrough time and mass transfer zone through the promotion of Pb(II) transfer onto adsorbent.

Effect of Pre-Rolling on the Mechanical Properties of AI-Mg-Mn Alloy (Al-Mg-Mn합금의 기계적(機械的) 성질(性質)에 미친 여비압재(予備圧在)의 영향(影響))

  • Ye, Gil-Chon;Maeng, Sun-Chae
    • Applied Microscopy
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    • v.4 no.1
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    • pp.5-10
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    • 1974
  • In this work the effect of pre-rolling on the homogenization and on the mechanical properties of 4.6% Mg-0.5% Mn-0.18% Cr-Al alloy has been studied. At room temperature tensile strength and elongation have been found to increase in the pre- rolled homogenized sample compared to those of the as cast sample. At $400^{\circ}C$ this pre-rolled homogenized sample has shown a little lower tensile strength and a remarkably higher elongation than the samples as casted or homogenized without pre-rolling. Metallurgical microstructure of the pre-rolled homogenized sample has shown conspicuously less secondary phase such as ${\beta}$-phase at the grain boundaries than the other samples. The difference of magnesium content between grain boundaries and within the grains has been also checked by EPMA. The test results show enhanced homogenizing effect by the pre-rolling before homogenizing heat treatment.

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Characterization of NOx Reduction on Filter Bag Support System at Low Temperature using Powder Type MnOx and V2O2/TiO2 Catalysts (분말형 MnOx와 V2O2/TiO2 촉매를 이용한 저온영역의 백필터 공정에서 질소산화물 제거 특성)

  • Kim, Byung-Hwan;Kim, Jeong-Heon;Kang, Pil-Sun;Yoo, Seung-Kwan
    • Journal of Korean Society for Atmospheric Environment
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    • v.26 no.1
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    • pp.1-9
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    • 2010
  • In this study, the selective catalytic reduction of $NO_x$ with ammonia was carried out in a filter bag support reactor. The experiments were performed by powder type $MnO_x$ and $V_2O_5$/$TiO_2$ catalyst at low temperature between 130 and $250^{\circ}C$. Also, the effect of $SO_2$ and $H_2O$ on the NO conversion was investigated under our test conditions. The powder type catalysts were analyzed by X-ray photoelectron spectrum (XPS), X-ray diffraction(XRD), scanning electron microscopy (SEM) and thermal gravimetric analysis (TGA). It was observed that NO removal efficiency of the powder type $V_2O_5$/$TiO_2$ catalyst was 85% at low temperature($200^{\circ}C$) under presence of oxygen and that of $MnO_x$ was 50% at the same condition. The powder type $V_2O_5$/$TiO_2$ catalyst, in conclusion, was found to be available for SCR reaction in a filter bag support system.