• Radiation Oncology Journal
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• v.29 no.3
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• pp.181-190
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• 2011

Purpose: Thoracic radiotherapy is a major treatment modality of stage III non-small cell lung cancer. The normal lung tissue is sensitive to radiation and radiation pneumonitis is the most important dose-limiting complication of thoracic radiation therapy. This study was performed to identify the clinical and dosimetric parameters related to the risk of radiation pneumonitis after definitive radiotherapy in stage III non-small cell cancer patients. Materials and Methods: The medical records were reviewed for 49 patients who completed definitive radiation therapy for locally advanced non-small cell lung cancer from August 2000 to February 2010. Radiation therapy was delivered with the daily dose of 1.8 Gy to 2.0 Gy and the total radiation dose ranged from 50.0 Gy to 70.2 Gy (median, 61.2 Gy). Elective nodal irradiation was delivered at a dose of 45.0 Gy to 50.0 Gy. Seven patients (14.3%) were treated with radiation therapy alone and forty two patients (85.7%) were treated with chemotherapy either sequentially or concurrently. Results: Twenty-five cases (51.0%) out of 49 cases experienced radiation pneumonitis. According to the radiation pneumonitis grade, 10 (20.4%) were grade 1, 9 (18.4%) were grade 2, 4 (8.2%) were grade 3, and 2 (4.1%) were grade 4. In the univariate analyses, no clinical factors including age, sex, performance status, smoking history, underlying lung disease, tumor location, total radiation dose and chemotherapy were associated with grade ${\geq}2$ radiation pneumonitis. In the subgroup analysis of the chemotherapy group, concurrent rather than sequential chemotherapy was significantly related to grade ${\geq}2$ radiation pneumonitis comparing sequential chemotherapy. In the univariate analysis with dosimetric factors, mean lung dose (MLD), $V_{20}$, $V_{30}$, $V_{40}$, MLDipsi, $V_{20}$ipsi, $V_{30}$ipsi, and $V_{40}$ipsi were associated with grade ${\geq}2$ radiation pneumonitis. In addition, multivariate analysis showed that MLD and V30 were independent predicting factors for grade ${\geq}2$ radiation pneumonitis. Conclusion: Concurrent chemotherapy, MLD and $V_{30}$ were statistically significant predictors of grade ${\geq}2$ radiation pneumonitis in patients with stage III non-small cell lung cancer undergoing definitive radiotherapy. The cutoff values for MLD and $V_{30}$ were 16 Gy and 18%, respectively.

• The Journal of Korea Assosiation for Disability and Oral Health
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• v.12 no.2
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• pp.96-100
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• 2016

Metachromatic leukodystrophy (MLD) is a progressive and degenerative neurological disease caused by a deficiency of the catabolic enzyme arylsulfatase A. Deficiency of arylsulfatase A results in accumulation of sulfatide in the white matter of the peripheral and central nervous system and it occurs demyelination as a result. The patient gradually goes through mental and motor failure. General symptoms of MLD include gait disturbance, mental deterioration, muscle rigidity and impaired swallowing. Inheritance of the disease is autosomal recessive. We report a dental caries treatment of a 3-year old boy with MLD. The patient underwent hematopoietic stem cell transplantation (HSCT) to slow the progression of the disease. He was suffered from difficulties of mastication and swallowing from the degenerative neurological symptom. He was ingesting food by both oral feeding and tubal feeding after he took percutaneous endoscopic gastrostomy (PEG). The cause of multiple caries was mainly presumed as patient's prolonged time of meal. The treatment was performed under general anesthesia considering patient's incompliance. Severely affected lower primary molars were treated with pulp treatment and restored with stainless steel crown. Others were restored with composite resin. There were no postoperative complications. MLD is life threatening progressive disease and also has an impact on unfavorable condition for oral health. Routine home oral care and periodic professional dental care should be emphasized to the caregiver of patient considering the susceptibility of dental caries. Not only the medical care, but periodic dental office visit would benefit the quality of life of the patient.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.45 no.6
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• pp.370-373
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• 2000

Acute toxicity of the pigment fraction of Heugjinjubyeo was investigated in male and female mice following oral administration. Major component of pigment fraction was analyzed as cyanidin 3-glucoside (C3G), which composition content was 96%. The pigment fraction as given at the single oral doses of 1000,3000 and 9000mg/kg in male and female mice did not show any abnormal behaviours, body weight loss or other toxic symptoms during observation period of 14 days. There were no dead mice among 6 mice at a single dose of 9000mg/kg. Thus, it is concluded that the minimum lethal doses (MLD) of the pigment extract might be more than 9000 mg/kg p.o., in male and female mice.

• Ocean Science Journal
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• v.42 no.4
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• pp.241-246
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• 2007

Northern Arabian Sea (NAS) between $17^{\circ}N-20.5^{\circ}N$ and $59^{\circ}E-69^{\circ}E$ was observed by using Argo float daily data fur about 9 months, from April 2002 through December 2002. Results showed that during April - May mixed layer shoaled due to light winds, clear sky and intense solar insolation. Sea surface temperature (SST) rose by $2.3^{\circ}C$ and ocean gained an average of 99.8 $Wm^{-2}$. Mixed layer reached maximum depth of about 71 m during June - September owing to strong winds and cloudy skies. Ocean gained abnormally low $\sim18Wm^{-2}$ and SST dropped by $3.4^{\circ}C$. During the inter monsoon period, October, mixed layer shoaled and maintained a depth of 20 to 30 m. November - December was accompanied by moderate winds, dropping of SST by $1.5^{\circ}C$ and ocean lost an average of 52.5 $Wm^{-2}$. Mixed layer deepened gradually reaching a maximum of 62 m in December. Analysis of surface fluxes and winds suggested that winds and fluxes are the dominating factors causing deepening of mixed layer during summer and winter monsoon periods respectively. Relatively big]h correlation between MLD, net heat flux and wind speed revealed that short term variability of MLD coincided well with short term variability of surface forcing.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.56 no.5
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• pp.834-840
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• 2007

A generator plays an important role in transferring an electric power to power system networks. The generator protection systems in Korea have been imported and operated through a tum-key from overseas entirely. Therefore, a study of the generator protection field has in urgent need for a stable operation of the imported goods, and for preparation of next generation protection system. The paper describes the fault detection algorithm using WT(Wave!et Transform) of currents for a generator protection. The fault current signals after executing a terminal fault modeling collect using a MA TLAB package, and calculate the wavelet coefficients through the process of a multi -level decomposition (MLD). The proposed algorithm for a fault detection using the Daubechies WT (wavelet transform) was executed with a C language for the command line function and for the real time realization after analyzing MATLAB's graphical interface. The advanced technique had complemented the defects of a DFT by applying a Daubechies WT. and had improved faster a speed and more accurate of fault discriminant than a conventional DFR.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.40 no.8
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• pp.301-306
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• 2003

This paper proposes a novel detection scheme using a radial basis function (RBF) network in a multi-input multi-output (MIMO) environment. In order to evaluate the performance of the proposed MIMO-RBF receiver, simulations are performed over the rich-scattering fading channel. Simulation results confirm that the proposed scheme shows the similar bit-error rate (BER) performance of a maximum likelihood detection (MLD) and outperforms Vertical-Bell Laboratories Layered Space-Time using minimum-mean-square-error nulling (VBLAST-MMSE) as well as VBLAST using zero-forcing nulling (VBLAST-ZF). Moreover, we investigate the effect on the performance of the number of RBF center with two modulation formats (BPSK and QPSK) and different number of transmit and receive antennas. The performance of the proposed detector is verified with respect to an initialization-rate of RBF centers.

• Physical Therapy Korea
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• v.10 no.4
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• pp.105-116
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• 2003

마사지 치료는 한국에서 가장 일반적인 치료 도구의 하나로써 물리치료에서 적용되고 있으며 방법도 빠르게 변하고 있다. 지금까지 여러 형태의 마사지 방법들이 국내 물리치료사에게 소개 되어왔지만 림프흡수 마사지는 임상결과가 이전의 연구에서 제시되어 왔음에도 제대로 소개되지 않아서 일반적인 치료적 마사지 방법의 하나로 사용되고 있지는 않았다. 이에 본 연구자들은 현재 국제 림프학회에서 공인된 보더 스쿨의 엠엘디 코스를 임상 물리치료사들에게 소개함으로 해서, 국내에서의 치료의 질을 한 층 더 높이는 기회가 되고자 한다. 공식적으로 공인된 보더 방법의 엠엘디 치료사가 되기 위해서는 보더 스쿨에서 교육하고 있는 모든 교육과정들(기초, 치료 I, 치료 II+III) 치료를 이수해야만 한다. 이수 후 지속적으로 자격을 인정받기 위해서는 2년에 한 번씩 재이수 과정을 마쳐야 하며 이런 과정을 통해 만성 부비동염, 부종, 화상, 관절염, 림프부종 등의 다양한 종류의 질환을 엠엘디를 이용하여 치료할 수 있게 된다. 결과적으로, 이 연구를 통해 보더의 엠엘디 과정을 소개함으로 해서 앞으로 국내 물리치료 분야에서 더 많은 림프와 암에 관련된 전문 엠엘디 치료사가 배출되기를 바라며 그러므로 한 층 국내 물리치료 분야의 질을 올릴 수 있는 기회가 되었으면 한다.

• Journal of Biomedical Engineering Research
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• v.30 no.6
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• pp.529-534
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• 2009

One of the characteristics of the hearing impaired is that their frequency selectivity is poorer than that of the normal hearing. To compensate this, formant enhancement algorithms and spectral contrast enhancement algorithms have been developed. However in some cases, these algorithms fail to improve the frequency selectivity of the hearing impaired. One of the reasons is the acoustic masking among enhanced formants. In this study, we tried to enhance the formants based on the individual masking characteristic of each subject. The masking characteristic used in this study was minimum level difference (MLD) between the first formant to the second formant while acoustic masking was occurred. If the level difference between the two formants in each frame is larger than the MLD, the gain of the first formant was decreased to reduce the acoustic masking that occurred among formants. As a result of the speech discrimination test, using formant enhanced speeches, speech discrimination score (SDS) of the speeches having differently enhanced formants was significantly superior to SDS of the speeches having equally enhanced formants. It means that suppression of the acoustic masking among formants improve frequency selectivity of the hearing impaired.

• The Transactions of the Korean Institute of Electrical Engineers P
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• v.64 no.1
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• pp.35-40
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• 2015

Generators are the most complex and expensive single element in a power system. The generator protection relays should to minimize damage during fault states and must be designed for maximum reliability. A conventional CDR(Current Differential Relaying) technique based on DFT(Discrete Fourier Transform) filter have the disadvantages that the time information can lead to loss in the process of converting the signal from the time domain to the frequency domain. A WT(Wavelet transform) and WT analysis is known that it is possible with the local analysis of the fault and transient signal. In this paper, to overcome the defects in the DFT process, an application of WT for fault detection of generator is presented. This paper describes an selection of mother Wavelet to detect faults of generator. Using collected data from the fault simulation with ATPdraw, we analyzed the several mother Wavelet through the course of MLD(multi-level decomposition) using MATLAB software. Finally, it can be seen that the proposed technique using detail coefficient of Daubechies level 2 which can be fault discriminant of generator.

• The Transactions of the Korean Institute of Electrical Engineers P
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• v.57 no.2
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• pp.91-95
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• 2008

The large AC generator fault may lead to large impacts or perturbations in power system. The generator protection control systems in Korea have been imported and operated through a turn-key from overseas entirely. Therefore a study of the generator protection field has in urgent need for a stable operation of the imported goods. In present, the algorithm using the current ratio differential relaying based DFT for stator winding protection or a fault detection had been applied that of internal fault protection of a generator. the DFT used for the analysis of transient state signal conventionally had defects losing a time information in the course of transforming a target signal to frequency domain. In this paper, the discrete wavelet transform (DWT) was applied a fault detection of the generator being superior to a transient state signal analysis and being easy to real time realization. The fault signals after executing a terminal fault modeling collect using a MATLAB package, and calculate the wavelet coefficients through the process of a muiti-level decomposition (MLD). The proposed algorithm for a fault detection using the Daubechies WT (wavelet transform) was executed with a C language and the commend line function for the real time realization after analyzing MATLAB's graphical interface. The advanced technique had improved faster a speed of fault discrimination than a conventional DFR based on DFT.