• 한국농공학회논문집
• /
• 제50권5호
• /
• pp.51-60
• /
• 2008

This study is to relate the bond characteristics of CFRP rebar in high strength concrete incorporated with silica fume(SF) and metakaolin(MK). An direct bond test were performed to evaluate the effect of SF and MK on bond properties of high-strength concrete and CFRP rebar. The high strength concrete mix included four SF and MK mixes with 0%, 5%, 10% and 15%. Results of bond performance experiment in relation to pullout vs slip behavior of FRP rebar and high strength showed better performance of SF than MK. Also, the results showed the improved bond strength as replacement ratio of SF and MK increased. The relative bond strength in which $1.3{\sim}3.2$ of estimated values were obtained.

• Journal of Korean Neurosurgical Society
• /
• 제29권9호
• /
• pp.1153-1160
• /
• 2000

Objectives : This study was undertaken to investigate the effect of noncompetitive NMDA receptor blocker, MK801 on motor recovery, SSEP and pathology in spinal cord injured rat. Methods : The effects of MK801 on neuronal function protection, SSEP, and pathology were measured on spinal cord injury rats which were divided into 6 groups according to dose, time of drug delivery and magnitude of injury. Spinal cord injury was made with the magnitude of 25gm-cm and 50gm-cm on 42 rats. BBB locomotor function test was performed to evaluate the motor power recovery in hindlimb for 2 weeks after injury. After motor function test was completed, SSEP was measured. Amplitude and latency of the P1, N1 peak was measured and compared between groups. Finally rats were sacrificed, and pathologic findings including measurement of area of necrotic cord were studied and compared between groups. Results : Motor recovery at 2 weeks was better in MK801 group comparing to saline control group. SSEP at 2 weeks showed no difference in N1, P1 latencies, but significantly greater amplitude in MK801 group, compared to saline control group. On light microscope, there was no specific histologic differences between experimental groups. The cystic necrotic area in coronal plane was measured and compared in each group. The necrotic area was significantly smaller in MK801 1mg/kg group(delivered after injury) than vehicle group. The necrotic area in MK801 5mg/kg group and MK801 1mg/kg group(delivered before injury) was smaller than vehicle group even though it was not statistically significant. Conclusion : From the above result, it is speculated that NMDA blocker, MK801 can improve impaired neuronal function in spinal cord injury.

• 한국해안·해양공학회논문집
• /
• 제27권2호
• /
• pp.94-104
• /
• 2015

우리나라의 연안은 도시개발, 인구증가가 지속적으로 나타나고 있으며, 이러한 점에서 해수면 상승으로 인한 연안재해 취약성이 가중될 것으로 전망되고 있다. 본 연구에서는 우리나라 연안의 20개 지역의 조위자료를 바탕으로 Mann-Kendall(MK) 검정, 선형회귀분석(OR), 분위회귀분석(QRA) 등을 이용하여 해수면상승에 대한 분석을 수행하였다. MK 검정결과 연평균조위의 경우 18개 지점에서 경향성이 통계적으로 유의한 것으로 분석되었으며, 연최대치의 경우에도 10개 지점에서 경향성이 통계적으로 유의(p < 0.05)한 것으로 평가되었다. QRA 방법을 이용하여 해수면의 경향성을 분위별로 평가한 결과 기존 회귀분석 방법에 비해 다각적인 경향성 검토가 가능하였다. QRA분석 결과 연평균해수면은 매년 1-6 mm의 범위에서 상승하고 있으며, 연최대해수면의 경우 1-20 mm의 범위에서 증가경향이 나타나고 있음을 확인할 수 있었다. 우리나라의 해수면상승의 경우 대부분 상향수렴 및 상향발산의 형태를 가지는 경향성을 나타내고 있었다. 향후 연구로서 이러한 경향성을 기반으로 연최대해수면 자료에 대한 비정상성빈도해석 절차의 개발 및 적용이 필요할 것으로 판단된다.

• 미생물학회지
• /
• 제37권2호
• /
• pp.151-157
• /
• 2001

위염 및 위궤양, 심이지장궤양, 위암의 주요한 발병 원인균으로 알려져 있는 Helicobacter pylori의 생육을 특이적으로 억제하는 유산균을 선발하기 위해서, 45종의 유산균에 대하여 paper disk법을 이용한 항균 효과, Caco-2세포에 대한 정착능, urease activity법을 이용한 H. pylori 억제능 등을 파악하고, 유산균 배양액과 H. pylori의 동시배양에 따른 요소 분해효소의 활성 변화와 우유 발효능 등을 실험하였다. H. pylori의 생육을 억제하는 물질의 생성 유무를 확인하기 위하여 paper disk법으로 유산균 배양액에 의한 H. pylori의 생육 억제환을 측정한 결과, 28종의 유산균에서 생육 억제환이 형성되었다. 대부분이 유산 생성에 의한 낮은 pH 때문인 것으로 판단되지만, 일부 균종에서는 항균성 물질에 의한 억제환이 형성되었다. 다른 유산균에 비해서 생육 억제환이 가장 큰 Lactobacillus gasseri MK-03 균주가 H. pylori에 대한 항균 활성이 가장 우수한 것으로 나타났다. 항균 활성을 나타낸 28종의 유산균을 대항으로 Caco-2 세포에 대한 정착능을 실험한 결과, 18종의 유산균에서 정착능이 확인되었으며, Bifidobacterium longum MK-26 균주가 가장 우수한 것으로 나타났다. 특히 반응 2시간 전에 미리 Caco-2 세포에 정착시켰을 때, H. pylori의 정착율은 0.105%에서 0.004%로 감소되었다. 한편 요소 분해효소 활성을 저해하여 H. pylori를 억제하는 유산균을 선발하기 위해서 항균활성이 인정되는 28종의 유산균을 대상으로 실험한 결과, 21종의 유산균에서 요소 분해효소 활성의 저해 효과가 나타났으며, 이중에서 Lb. acidophilus MK-07 균주가 가장 우수한 것으로 판명되었다. 따라서 Lb. gasseri MK-03 균주는 항균 활성에서, Lb. acidophilus MK-07 균주는 요소 분해효소의 활성 억제에 의해서, Bif. longum MK-26 균주는 정착능 저해에 있어서 각각 우수한 H. pylori 생육 억제능을 나타냈다. 한편 최종적으로 선발된 3종의 유산균과 대조균주로서 13종의 유산균에 대해서는 우유 배양실험을 실시한 결과, 3종의 선발균주 모두가 발효유 제품에의 응용 적합성을 나타냈다.

• Structural Engineering and Mechanics
• /
• 제31권1호
• /
• pp.1-10
• /
• 2009

An experimental investigation was conducted to evaluate the performance of mortars with and without Metakaolin (MK) exposed to elevated temperatures $200^{\circ}C$, $400^{\circ}C$, $600^{\circ}C$ and $800^{\circ}C$ for two hours. The binder to sand ratio was kept constant (1:5.23). The ordinary Portland cement (OPC) was replaced with MK at 0%, 5%, 10% 20% and 30%. All mixtures were designed to have a flow of $94{\pm}5%$. The compressive strength of mortars before and after exposure to elevated temperature was determined. The formation of various decomposition phases were identified using X-ray diffractometry (XRD) and differential thermal analysis (DTA). The microstructure of the mortars was examined using scanning electron microscope (SEM). Test results indicated that MK improves the compressive strength before and after exposure to elevated temperature and that the 20% cement replacement of MK is the optimum percentage.

• Environmental Engineering Research
• /
• 제21권1호
• /
• pp.58-68
• /
• 2016

The study explored droughts using the Standardized Precipitation Index (SPI) in the northwestern region of Bangladesh, which is the drought prone area. In order to assess the trend and variability of monthly rainfall, as well as 3-month scale SPI, non-parametric Mann-Kendall (MK) tests and continuous wavelet transform were used respectively. The effect of climatic parameters on the drought in this region was also evaluated using SPI, with the Southern Oscilation Index (SOI) by means of the wavelet coherence technique, a relatively new and powerful tool for describing processes. The MK test showed no statistically significant monthly rainfall trends in the selected stations, whereas the seasonal MK test showed a declining rainfall trend in Bogra, Ishurdi, Rangpur and Sayedpur stations respectively. Sen's slope of six stations also provided a decreasing rainfall trend. The trend of the SPI, as well as Sen's slope indicated an increasing dryness trend in this area. Dominant periodicity of 3-month scale SPI at 8 to 16 months, 16 to 32 months, and 32 to 64 months were observed in the study area. The outcomes from this study contribute to hydrologists to establish strategies, priorities and proper use of water resources.

• 생명과학회지
• /
• 제24권8호
• /
• pp.880-886
• /
• 2014

제주 연안에서 분리한 해양유래미생물 14종을 이용하여 어류질병세균 4종에 대해 항균활성을 탐색하였다. 그 결과, MK-11이 그람양성균인 Streptococcus iniae, Streptococcus parauberis에 대하여 항균활성을 나타내었다. 특히 S. iniae에 대해 뛰어난 활성을 보였으며 최소 억제 농도는 $250{\mu}g/ml$로 나타났다. 최적 생장 조건은 $25^{\circ}C$, pH 6.0, 1% NaCl로 나타났으며, 최적 배지 조건은 탄소원 sorbitol, 질소원 yeast extract, 무기염 dipotassium phosphate ($K_2HPO_4$)으로 나타났다. API 50CHB kit 결과, D-sorbitol 과 D-mannitol을 추가적으로 분해하여 산을 생성하였다. 16S rDNA 염기서열 분석결과, MK-11은 Paenibacillus polymyxa, P. jamilae, P. rasilensis 와 각각 99.78%, 99.43%, 99.39%의 유사도를 나타내었다. 이처럼 다양한 특성을 지닌 Paenibacillus sp. MK-11은 그람양성균에 대한 새로운 항생물질로서의 이용가능성을 보였으며, 추가 연구를 통해 in vivo에 적용 가능할 것으로 사료된다.

• 한국콘크리트학회:학술대회논문집
• /
• 한국콘크리트학회 2003년도 가을 학술발표회 논문집
• /
• pp.457-460
• /
• 2003

This paper discusses laboratory evaluations to assess the physical properties of antiwashout underwater concrete (AWC) containing pozzolanic materials such as fly ash (FA), blast furnace slag (SG) and metakaolin(MK). For the experiments, pH value, suspended solids, slump flow, efflux time and compressive strength were tested. According to the results from compressive strength test, MK10 showed the very high compressive strength characteristic during the entire curing days, but the rate of strength development was decreased as time goes by.

• Steel and Composite Structures
• /
• 제23권5호
• /
• pp.543-555
• /
• 2017

The mechanical properties of steel fiber reinforced high strength concrete (SFRHSC) made with binary and ternary blends of metakaolin (MK) and ground pumice (GP) are investigated in this study. The investigated properties are ultrasonic pulse velocity ($U_{pv}$), compressive strength ($f_c$), flexural strength ($f_f$) and splitting tensile strength ($f_{st}$) of SFRHSC. A total of 16 steel fiber reinforced concrete mixtures were produced by a total binder content of $500kg/m^3$ for determining the effects of MK and GP on the mechanical properties. The design $f_c$ was acquired from 70 to 100 MPa by using a low water-binder ratio of 0.2. The test results exhibit that high strength concrete can be obtained by replacing the cement with MK and GP. Besides, correlations between these results are executed for comprehending the relationship between mechanical properties of SFRHSC and the strong correlations are observed between these properties. Moreover, two models in the gene expression programming (GEP) for predicting the $f_c$ of SFRHSC made with binary and ternary blends of MK and GP have been developed. The results obtained from these models are compared with the experimental results. These comparisons proved that the results of equations obtained from these models seem to agree with the experimental results.

• 한국의류산업학회지
• /
• 제15권4호
• /
• pp.630-634
• /
• 2013

Cow leather coated with polyurethane film that contains various organic photosensitizers was investigated to demonstrate the antimicrobial properties in the application of the material to protective clothing and home appliances. To prepare the antimicrobial coating on leather surfaces with high potency against microbes, photoactive agents, such as benzophenone (BP), 4,4'-bis(dimethylamino) benzophenone (MK), 4,4'-dihydroxybenzophenone (DHBP) and methylene blue (MB), were incorporated into polyurethane-based coating solutions. The photoactive antimicrobial agent treated leather samples were characterized by SEM, color appearance, color fastness against abrasion, and antimicrobial tests. The optical properties of organic photosensitizers indicated that active UV absorbance ranges were different: BP (around 250 nm), MK (around 360 nm), DHBP (around 305 nm) and MB (around 295 nm &570 nm-685 nm). The intensity of the UV absorbance curve at the UVA light wavelength for the antimicrobial test showed the highest value with MK; subsequently, this was followed by MB, DHBP and BP in decreasing order. The treated-leather samples demonstrated excellent antibacterial activity under UVA light. The antimicrobial effects for the Staphylococcus aureus were superior to Escherichia coli. Moreover, the polyurethane finishing showed an effective durability to abrasion. The overall results indicated that DHBP is the most suitable PU coating additive to provide antimicrobial properties to leather as well as color and surface appearance than MK, MB, and BP.