• Title/Summary/Keyword: MIP-1

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Reappraisal of anatomical diversity of lateral circumflex femoral artery with its substantial clinical applicability: cadaveric study

  • Anju Chaudhary;Apurba Patra;Pooja Garg
    • Anatomy and Cell Biology
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    • v.57 no.3
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    • pp.346-352
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    • 2024
  • Studies reveal variations in the in the origin, number, and branching patterns of the lateral circumflex femoral artery (LCFA). The present study aimed to document such variations and their potential clinical applicability. Thirty-two femoral triangles of 16 embalmed adult human cadavers were dissected to investigate the variation in the origin, number, and branching patterns of LCFA. The main branches of the LCFA were tracked independently for numerical variations in branching pattern. The distance between the origin of LCFA and mid inguinal point (MIP) was also measured in each case. LCFA was most commonly arising from profunda femoris (PF), followed by femoral artery (FA) and common trunk of the femoral artery (CFA). Duplication LCFA was observed in 15 (46.87%) limbs, in 5 (31.25%) cases duplication was only on right side, in 4 (25%) cases duplication was only on left side and in 3 (18.75%), duplication was bilateral. Cases with duplication of LCFA, showed numerical variations with descending pattern being the most common. The average distance of LCFA1 and LCFA2 from mid-inguinal point was 5.77±1.35 cm and 6.14±2.05 cm respectively. Detailed information regarding the occurrence of duplication will be great importance for surgeons, interventional radiologists, and other medical professionals performing procedures in the femoral region. Knowledge of variation of branching pattern of LCFA is utmost important as surgeons use the descending branch of the LCFA in bypass grafting and vascular reconstruction surgeries.

C1qa deficiency in mice increases susceptibility to mouse hepatitis virus A59 infection

  • Kim, Han-Woong;Seo, Sun-Min;Kim, Jun-Young;Lee, Jae Hoon;Lee, Han-Woong;Choi, Yang-Kyu
    • Journal of Veterinary Science
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    • v.22 no.3
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    • pp.36.1-36.12
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    • 2021
  • Background: Mouse hepatitis virus (MHV) A59 is a highly infectious pathogen and starts in the respiratory tract and progresses to systemic infection in laboratory mice. The complement system is an important part of the host immune response to viral infection. It is not clear the role of the classical complement pathway in MHV infection. Objectives: The purpose of this study was to determine the importance of the classical pathway in coronavirus pathogenesis by comparing C1qa KO mice and wild-type mice. Methods: We generated a C1qa KO mouse using CRISPR/Cas9 technology and compared the susceptibility to MHV A59 infection between C1qa KO and wild-type mice. Histopathological and immunohistochemical changes, viral loads, and chemokine expressions in both mice were measured. Results: MHV A59-infected C1qa KO mice showed severe histopathological changes, such as hepatocellular necrosis and interstitial pneumonia, compared to MHV A59-infected wild-type mice. Virus copy numbers in the olfactory bulb, liver, and lungs of C1qa KO mice were significantly higher than those of wild-type mice. The increase in viral copy numbers in C1qa KO mice was consistent with the histopathologic changes in organs. These results indicate that C1qa deficiency enhances susceptibility to MHV A59 systemic infection in mice. In addition, this enhanced susceptibility effect is associated with dramatic elevations in spleen IFN-γ, MIP-1 α, and MCP-1 in C1qa KO mice. Conclusions: These data suggest that C1qa deficiency enhances susceptibility to MHV A59 systemic infection, and activation of the classical complement pathway may be important for protecting the host against MHV A59 infection.

An Interactive Multi-criteria Group Decision Making with the Minimum Distance Measure (최소 거리척도를 이용한 대화형 다기준 그룹 의사결정)

  • Cho, Namwoong;Kim, Jaehee;Kim, Sheung-Kown
    • Journal of Korean Institute of Industrial Engineers
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    • v.32 no.1
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    • pp.42-50
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    • 2006
  • The multi-criteria group decision making (MCGDM) problem is to determine the best compromise solution in a set of competing alternatives that are evaluated under conflicting criteria by decision maker (DM)s. In this paper, we propose a mixed-integer programming (MIP) model to solve MCGDM. The existing method based on minimizing a distance measure such as Median Approach can not guarantee the best compromise solution because the element of median point vector is defined with respect to each criteria separately. However, by considering all criteria simultaneously, we generate median point that is better for locating the best compromise solution. We also utilize the concept of spatial dispersion index (SDI) to produce a threshold value, which is used as a guideline to choose either the Utopian Approach or the Median Approach. And we suggest using CBITP (Convex hull of individual maxima Based Interactive Tchebycheff Procedure) to provide DMs with various Pareto-optimal solutions so that DMs have broad range of selection.

Effect of Formaldehyde on the Water Resistance of MDF Cement Composites

  • Nho, Jun-Seok;Park, Choon-Keun;Park, Sang-Heul
    • The Korean Journal of Ceramics
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    • v.5 no.3
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    • pp.278-283
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    • 1999
  • Formaldehyde has widely been used for the cross-linking of polyvinyl alcohol polyvinyl alcohol polymer. The effects of formaldehyde on the water resistance of MDF cement composites were investigated as a function of types of catalyst, base or acid, and the amount of formaldehyde. The acetalization, reaction of OH group of PVA with aldehyde, was ended incompletely under base atmosphere. However, by addition of citric acid, the cross-linking of PVA polymer could be acheved through acetalization of PVA and formaldehyde. The effects of these different patterne according to the types of catalyst on the water resistance of MDF cement were studied by the preparation of PVA films and MDF composites. Thanks to the cross-linking reaction of PVA polymer chains by formaldehyde, the modified PVA films and MDF composites showed a good water-resistant propety. The modified MDF cement composite to which 3 wt% formaldehyde and 1 wt% cirtic acid were added showed 80% of initial flexural strength and good interfacial state between cement grain and polymer matrix. However, 4 wt% formaldehyde deteriorted the processing conditions, microstructures and eventually the flexural strength, causing sharp increase in the viscosity of sample dough during the mixing process. To study the relatins of flexural strength and interface of cement grain and polymer matrix, SEM and MIP measurement were performed.

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Biocompatibility of oxidized alginate/gelatin/BCP -based hydrogel composites

  • Phuong, Nguyen Thi;Min, Young-Ki;Yang, Hun-Mo;Song, Ho-Yeon;Lee, Byong-Teak
    • Proceedings of the Materials Research Society of Korea Conference
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    • 2010.05a
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    • pp.40.2-40.2
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    • 2010
  • In this study, oxidized alginate/gelatin/biphase calcium phosphate (BCP)- based hydrogel composites were fabricated. Alginate sodium was oxidized by periodate. The oxidized product was confirmed by using $^1H$ and $^{13}C$ NMR spectra. The number average molecular weight ($M_n$), the average molecular weight ($M_w$) of the oxidized alginate were determined by Gel Permeation Chromatography (GPC). The hydrogel was formed from the oxidized alginate and gelatin solution via Schift-base reaction. The hydrogel showed a highly porosity by a Scanning Electron Microscope (SEM) and Mercury Intrusion Porosimetry (MIP). Crosslinked density of the gel matrix were assessd by trinitrobenzene sulfonic acid (TNBS) assay that shows a high effect on swelling ratio. Increment of the crosslinked desity resulted in enhancing compressive strength of the hydrogel composite. The cytotoxity of hydrogel was assessed with osteoblast MG-63. The hydrogel composites show a high compatibility. The obtained results showed a potential application for bone regeneration in future.

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A Design of the Signal Processing Hardware Platform for OFDM Communication Systems (OFDM 통신 시스템을 위한 신호처리 하드웨어 플랫폼 개발)

  • Lee, Byung-Wook;Cho, Sung-Ho
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.33 no.6C
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    • pp.498-504
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    • 2008
  • In this paper, an efficient hardware platform for the digital signal processing for OFDM Communication systems is presented. The hardware platform consists of a single FPGA, two DSPs with 8000 MIPS of maximum at 1 GHz clock, 2-channel ADC and DAC supporting maximum 125 MHz sampling rate, and flexible data bus architecture, so that a wide variety of baseband signal processing algorithms for practical OFDM communication systems may be implemented and tested. The IEEE 802.16 software modem is also presented in order to verify the effectiveness and usefulness of the designed platform.

The Resistance of Penetrability and Diffusion of Chloride Ion in Blended Low Heat Type Cement Concrete (저발열형 시멘트 콘크리트의 염소이온 침투$\cdot$확산에 대한 저항성)

  • 문한영;신화철
    • Journal of the Korea Concrete Institute
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    • v.11 no.4
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    • pp.31-41
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    • 1999
  • Blended Low Heat type cement is ground granulated blast furnace slag and fly ash mixed ternary with ordinary portland cement. From the viewpoint of X-ray patterns of domestic LHC, the main components of cement such as $C_2$S, $C_3$A, $C_3$S are considerably reduced. Therefore the heat evolution of LHC paste is 42cal/g lower than of OPC paste. At early age, the compressive strength development of LHC concrete is delayed, but the slump loss ratio of fresh concrete is reduced more than 20% with elapsed time. The penetrability of LHC is lower than that of OPC by 1/7.8 with the penetrability of chloride ion into the concrete until the age of 120 days. And the PD Index value of LHC is 0.44$\times$10-6 $\textrm{cm}^2$/s, which indicates only 39.3% of OPC. From the Mercury Intrusion Porosimetry test of cement past, we know that the pore size of LHC is more dense than that of OPC by production of C-S-H.

Economics of Self-Generation by Natural Gas Industry Using the Mixed Integer Program (혼합정수계획법을 이용한 천연가스(LNG) 산업의 자가발전소 건설에 대한 경제성 분석)

  • Lee, Jeong-Dong;Byun, Sang-Kyu;Kim, Tai-Yoo
    • IE interfaces
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    • v.13 no.4
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    • pp.658-667
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    • 2000
  • Seasonal variation of natural gas demand coupled with rigid and stable import pattern of gas represents the characteristic feature of the Korean Liquified Natural Gas(LNG) industry. This attribute has required a huge amount of investment for the construction of storage facility. Thus, to minimize the supply cost, it is legitimate to reduce storage requirement itself. In this study, we combine three alternative methods to deal with the storage requirement to minimize the supply cost. Those are (1) adding additional storage tanks, (2) inducing large firm customers, and (3) constructing gas-turbine self generation facilities. Methodologically, we employ the mixed integer program (MIP) to optimize the system. The model also consider demand and price-setting scheme in separate modules. From the results, it is shown that if alternatives are combined optimally, a number of storage tanks can be reduced substantially compared with the original capacity plan set by the industry authorities. We perform various sensitivity analyses to check the robustness of the results. The methodology presented in this study can be applied to the other physical network industry, such as hydraulics. The empirical results will shed some light on the rationalization of capacity planning of the Korean natural gas industry.

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A study on High-Precision Position Control of Permanent Magnet Synchronous Motor for Semiconductor Equipments (반도체 제조 장비용 영구자석형 동기전동기의 고분해능 위치제어에 관한 연구)

  • Hong Sun-Ki;Hwang In-Sung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.6 no.5
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    • pp.432-438
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    • 2005
  • In this paper, the high precision position control of AC Servo motor for semiconductor equipment is studied. The control system was implemented using TI DSP TMS320F2812 which has 150 MIPS speed for next generation motor control. The controlled 100W PMSM motor has 2,500 ppr optical incremental encoder. The control system has speed controller and current controller to control the motor position. The encoder pulses are divided into 4 times, which has 10,000 ppr and the motor system has the position accuracy of 1/10,000. If the resolution of the encoder is increased, the resolution of the position control will be increased.

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Experimental study on treatment of waste slurry by vacuum preloading with different conditioning agents

  • Wu, Yajun;Jiang, Haibo;Lu, Yitian;Sun, Dean
    • Geomechanics and Engineering
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    • v.17 no.6
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    • pp.543-551
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    • 2019
  • In China, serious environmental problems are induced by the extremely soft construction waste slurries in many urban areas, and there is no appropriate method to treat it presently. In this paper, four model tests were conducted to investigate the efficiency of waste slurry treatment by combining three conditioning agents which can change characteristics of the slurries with a traditional vacuum preloading method. The tests of size analysis of particle aggregate were conducted to investigate the influence of different conditioning agents on the size distributions of particle aggregate. During the model test, the discharged water volumes were monitored. The pore-size distribution and void ratio of the waste slurries after the vacuum preloading were measured by mercury intrusion porosimetry (MIP). It is found that 1) During the natural precipitation, volume of water out of the organic agent is higher than that of the mixed agent, but it is smaller than that of the mixed agent in the vacuum preloading stage; 2) the mixed agent has a higher total volume of water out than the organic agent and the inorganic agent after test, while the organic agent and the inorganic agent have little difference with respect to the drainage effect. The results demonstrate that the combination of mixed conditioning agent and vacuum preloading for the solid-liquid separation in waste slurry has a satisfactory effect and can be applied in engineering practice.