• Proceedings of the Mineralogical Society of Korea Conference
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• 2003.05a
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• pp.67-67
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• 2003

The chemical compositions and textural relationships of the Nb-Zr oxide minerals including pyrochlore [ideally (Ca,Na)$_2$Nb$_2$O$\sub$6/(OH,F), with up to 24% UO$_2$ and 16% Ta$_2$O$\sub$5/] and baddeleyite [ideally ZrO$_2$, with up to 6% Nb$_2$O$\sub$5/] in the Sokli carbonatite complex, Kola Peninsula, Arctic are described. These two minerals in carbonatites are the major hosts for the HFSEs such as U, Th, Ta, Nb, Zr and Hf and thus are interest both economically and petrologically. The Sokli carbonatite complex (360-370 Ma) in Northern Finland, which forms a part of the Paleozoic Kola Alkaline Province (KAP), is mainly composed of multi-stages of carbonatite and phoscorite associations (P1-C1 P2-C2, P3-C3, D4 and D5) surrounded by altered ultramafic rocks (olivinite and pyroxenite) and cut by numerous small dikes of ultramafic lamprophyre. The Sokli complex contains the highest concentration in niobium and probably in tantalum, which are economically very important to modern steel technology, among the ultramafic-alkaline complexes of the KAP. Pyrochlore and baddeleyite mostly concentrate in the phoscorites. Pyrochlores in the Sokli complex are generally rounded octahedra and cubes in shape, red brown to grey yellow in color, and 0.2 to 5 mm in size. They are found in all calcite carbonatites, phoscorites and dolomite carbonatites, except P1-C1 rocks. These pyrochlores display remarkable zonations which depend on host rock compositions, and have significant compositional variations with evolution of the Sokli complex. The common variation scheme is that (1) early pyrochlore is highly enriched in U and Ta; (2) these elements decrease abruptly in the intermediate stage, while Th and Ce increase, and (3) late stage pyrochlore is low in U, Ta, Th, and Ce, and correspondingly high in Nb. Baddeleyites in the Sokli complex occur in the early P1-C1 and P2-C2 rocks and rarely in P3. They crystallized earlier than pyrochlores, and occasionally show post-magmatic corrosion and replacement. The FeO and TiO$_2$ contents of baddeleyites are much lower than those of the other terrestrial and lunar baddeleyites, whereas Nb$_2$O$\sub$5/ and Ta$_2$O$\sub$5/ contents are the highest among the reported compositions. Ta/Nb and Zr/Nb ratios of pyrochlores and baddeleyites decrease towards later stage facies, which is in accordance with the whole rock compositions. The variation of Ta/Nb and Zr/Nb ratios of pyrochlores and baddeleyites is considered to be a good indicator to trace an evolution of the carbonatite complexes.

• Proceedings of the Korean Biophysical Society Conference
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• 2003.06a
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• pp.37-37
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• 2003

We have shown the $Ca^{2+}$-activated chloride current is present in cardiac myocyte in rabbit pulmonary vein (Kim et al., 2002). This current amplitude was increased as [N $a^{+}$]$_{i}$ was increased and we suggested this chloride current may be involve in the spontaneous action potential frequency change. Since this current is activated by the increase of intracellular $Ca^{2+}$, we would like to test what is the inducer of the increase of [C $a^{2+}$]$_{i}$ between a L-type $Ca^{2+}$-current or a reverse mode of N $a^{+}$-C $a^{2+}$ exchange current. White rabbit (1.5 kg) was used and anesthetized with Ketamin (100 mg/kg). Pulmonary vein (PV) was isolated and sleeve area between left atrium and PV was dissected. Using collagenase (Worthington 0.7 mg/cc), single cardiac myocytes were isolated. In the presence of 15 mM of N $a^{＋}$, three steps of voltage pulses were applied (holding potential : -40 ㎷, -80 ㎷ for 50 msec, 30 ㎷ for 5 msec, 10 ㎷ steps from -70 ㎷ to 60 ㎷). The inward and outward tail current was activated after brief 5 msec prepulse. The outward tail current was blocked by the removal of extracellular chloride substituted by glucuronic acid or by a chloride channel blocker, 5 mM 9-AC. But the inward tail current was still remained even though the amplitude was decreased. The reversal potentials were changed to the direction of the change of chloride equilibrium potential ( $E_{Cl}$ ) but the shift of equilibrium potential was not enough to match to the theoretical equilibrium potential shift. In the presence of L-type $Ca^{2+}$ channel blocker, nifedipine 1 uM, inward tail currents were greatly reduced but the outward current tail currents were still remained. In the presence of N $a^{+}$-C $a^{2+}$ exchange current blocker, 10 uM KB-R7943, the inward and outward tail currents were blocked almost completely. We tried to test the $Ca^{2+}$sensitivity of the chloride current with various [C $a^{2+}$]$_{i}$ in pipette solution from 100 nM to 1 uM but we failed to activate $Ca^{2＋}$-activated chloride currents even though the cell became contracted in the presence of 1 uM $Ca^{2+}$. From these results, we could conclude that the increase of [C $a^{2+}$]$_{i}$ to activate the outward $Ca^{2+}$-activated chloride current was mainly induced by the activation of the reverse mode of N $a^{+}$-C $a^{2+}$ exchanger, But for the increase of [C $a^{2+}$]$_{i}$ to activate the inward tail current, L-type $Ca^{2+}$ current may be the major provoking current. Since the cytosolic increase of [C $a^{2+}$]$_{i}$ through pipette solution have failed to activate $Ca^{2+}$-activated chloride current, this chloride current may have very low $Ca^{2+}$ sensitivity or a comparmental increase $Ca^{2+}$ such as in subsarcolemmal space may activate the chloride current. Since there are several reports and models that the increase of $Ca^{2+}$ in subsarcolemmal space would be over several to tens of uM, both possibility may be valid together.uM, both possibility may be valid together.

• Journal of Korean Society of Transportation
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• v.26 no.3
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• pp.179-186
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• 2008

It is crucial in traffic flow management to maintain productivity and the traffic stability at the same time especially under congested traffic conditions. This issue has not been explicitly addressed under the intelligent transportation system environments. However, the ubiquitous transportation system environments make it possible to collect the data for each vehicle's position and velocity and to perform more sophisticated traffic flow management at individual vehicle or platoon level through V2V and V2I communications. In this paper, a preventive traffic flow management scheme is proposed, in which the objective is to maintain traffic flow stability while the productivity of the system is not decreased. The management scheme is proposed based on Greenshield's model because it is simple and easy to handle. It is considered that further research should be performed to evaluate the various traffic flow models.

• Journal of Life Science
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• v.22 no.12
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• pp.1637-1643
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• 2012

This study investigated the effects of PG on IL-$1{\beta}$ expression and determined cellular factors involved in PG-mediated IL-$1{\beta}$ up-regulation in mononuclear cells in order to understand the molecular mechanisms underlying inflammatory responses associated with bacterial pathogen-associated molecular patterns in the diseased artery. Exposure of human monocytic leukemia THP-1 cells to PG resulted in enhanced secretion of IL-$1{\beta}$ and also profound induction of the IL-$1{\beta}$ gene transcript. These effects were abrogated by OxPAPC, an inhibitor of TLR-2/4. Pharmacological inhibitors such as U0126, SP6001250, Akti IV, rapamycin, and DPI also significantly attenuated PG-mediated IL-$1{\beta}$ up-regulation. However, polymyxin B did not influence the IL-$1{\beta}$ expression. This study indicates that PG contributes to vascular inflammation in atherosclerotic plaques by up-regulating expression of IL-$1{\beta}$ via TLR-2, Akt, mTOR, MAPKs, and ROS.

• Korean Journal of Crystallography
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• v.2 no.2
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• pp.28-31
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• 1991

4-크로로-4'-메톡시-2-니트로디페닐아민, (C12H11N2O3CL, FW=278.70)의 단것세포 상수는 a=8,169(3), b=8.883(1), c=9.150(1) h, α =82. 98(1), β=104.80(2), y=101.43(2)", V=627.3 A3, F(000)=288.0, Dc=1.48g/cm3, u=3.06cm-1, 7=295" K, 공간군 Pi, 번호 2, 삼사 정계 이며, Z=2이다. λ (Mo-Ka)=0.7107A을 사용 하여 수집한 독립적인 회절 반점 1541개로 구조분 석한 최종 신뢰도 값은 각각 R=0.032, Rw=0.033 이며, S=0.46이다. 본 화합물은 암모니아의 두개 의 수소 대신에 4-크로로-페닐기와 4-메톡시-페닐기로 치환된 물질로써, 질소와 두 페닐기 사이의 각과 결합거리 들은 각각 125.42", 1.362 및 1.428 A 인바 수소와 함께 SP2_혼성결합을 하고있다. 질소를 포함한 두 면간 각은 63.29"이다. 분자간 어 떠 한 수소결합을 하고 지지 않다.

• The korean journal of orthodontics
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• v.32 no.1 s.90
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• pp.33-42
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• 2002

This study was performed to compare the pattern of dentoalveolar characteristics in different vertical and anteroposterior skeletal types in skeletal Class III malocclusion. The samples selected for this study were consisted of 60 subjects(29 males and 31 females, mean age; 19.7 years) in Class III group, 43 subjects(14males and 29 females, mean age : 20.5 years) in normal group. The findings of this study were as follows : 1. The IMPA of the Class III group was smaller than that of the Class I group(p<0.01). 2. In the Class III groups, SNB and NtoPog had negative correlation with IMPA(p<0.01). The SNB and NtoPog had correlations with SNU1, FHU1 and PalU1(p<0.01) in the male samples, and in the female samples, the SNB and NtoPog had correlations with SNU1(p<0.01). 3. In the Class III male samples, SNMP, FMA, PalMP had negative correlation with IMPA(p<0.01). SNMP, FMA, PalMP had not significant correlation with SNU1, FHU1, PalU1. In the Class III female samples, FMA, PalMP had negative correlation with IMPA(p<0.01). 4. In the high angle group of Class III samples, SNU1, IMPA is smaller than that of low angle group of Class III samples(p<0.05).

• 한국생물공학회:학술대회논문집
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• 2000.04a
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• pp.374-377
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• 2000

A strain of Pseudomonas sp. BCNU 154 was isolated from contaminated soil with orangic solvents as the sole source of carbon and energy. It utilized an exceptionally wide aromatic substrates. The strain BCNU 154 was able to utilize toluene, p-xylene, ethylbenzene, cumene, as the only carbon and energy source. When toluene or p-xylene was used as the sole carbon and energy source, the compound was rapidly degraded with significant increase in biomass concentruction. The biodegradation of this compound was observed when ethylbenzene or cumene was supplied on the carbon source and energy source, which may be a candidate extremophilic bacterium for the bioremediation technology.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.23 no.2
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• pp.108-113
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• 2013

Objectives: Although several cases of lung diseases caused by indium have been reported in Japan, the United States and China, South Korea, which is estimated to have been the world's largest consumer of indium, has not yet established a criteria for the diagnosis of lung diseases caused by indium exposure. In this study, we tried to determine the applicability of the Krebs von den lungen-6, which has been widely recognized for its use with interstitial lung disease in Japan, as a biological exposure index for indium. Methods: Methods: The analysis of indium in serum was conducted by inductively coupled plasma mass spectrometry and the analysis of KL-6 in serum was carried out using enzyme-linked immunosorbent assay kit. Results: The indium levels in serum were distributed from below the detection limit to a peak of $125.78{\mu}g/L$, and the values of the KL-6 were distributed from 104.5 U/mL to 2162.2 U/mL. The serum indium and KL-6 showed good correlation ($R^2$=0.389,pfortrend=0.000) and smoking did not affect the KL-6. Conclusions: The usefulness of KL-6 as a specific biomarker for interstitial lung disease has been recognized. In addition, it is expected that effective prevention of health problems can be achieved by determining the lung-damage progress at an early stage according to individual susceptibility.

• Journal of Convergence for Information Technology
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• v.10 no.6
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• pp.109-118
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• 2020

The purpose of this research is to investigate the effects of interaction, gender, and age on preschool children's intimate relationship with entertainment robot dog. For this purpose, two kinds of experiments were conducted for 70 preschool children in day care centers in Seoul. Experiment 1 relates to the interaction with entertainment robot dog, 34 children aged 5 years (17 experimental groups, 17 comparative groups). Experiment 2 was a study on the effects of gender and age. A total of 36 children (pre- and post-group) of 12 children aged 3, 4, and 5 years old were included. This study interviewed the number of distributions and the motivations for distribution by using the "Dividing Game(Distribution Principle)" interview. As a result, firstly the group experiencing the interaction felt more intimate with the entertainment robot dog, and the reason was emotional factor the most(Experiment 1). Second, gender had no significant effect on entertainment robot dog intimacy and age showed a reverted U-shape. The above results are meaningful in that it reveals what kind of factors affecting the intimacy between the preschooler and entertainment robot dog.

• Spatial Information Research
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• v.16 no.2
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• pp.263-278
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• 2008

Nowaday, local governments have planned to manage intelligent underground facilities through the u-City project. But, the intelligent underground facilities are in need of the progressive approach because of the required huge financial resources. Therefore, the objectives of this research are (1) to prioritize the monitoring items of sensing technology developments, (2) to study technological feasibilities, and (3) to discover the killer application which expands ripple effects on economy. To achieve these objectives, final monitoring items were derived from the business analysis of the water supply, the local government survey, the hearing expert opinions and so on. The priority order of final monitoring items were technology developments of (1) the flowmeter flux, (2) the water leakage/crack, (3) the pressure of water supply pipes, and (4) the flux of filtration plants. The research significance is obtained from the derivation and the evaluation of the priority order and the actual demand for the water supply facility management. And, the research results will contribute to the strategic planning for the underground facility intelligence.