• Title/Summary/Keyword: MGC

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Marketer Generated Content on Social Media: How to Support Corporate Online Distribution

  • ZHONG, Xin;YAN, Jinzhe
    • Journal of Distribution Science
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    • v.20 no.3
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    • pp.33-43
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    • 2022
  • Purpose: More and more marketers use social media platforms to create and spread information called Marketer Generated Content (MGC) to inform consumers of products. MGC often embeds product purchase links, thus directing consumers to online distribution channels for online purchases. This study examined the effect of social media MGC on consumers' willingness to buy online in the anchor of consumers' perspective to answer the question of "how social media generated content support corporate online distribution". Research design, data, and methodology: According to the means-end-chain theory, we introduce perceived value and continuous following intention as chain mediators to explain the mechanism of MGC influence on consumers' online purchase intention and consider product type to discuss boundary conditions. Two experiments were designed to test hypothesizes. Results and Conclusion: First, emotional MGC (vs. informational MGC) has lower (higher) perceived utility (hedonic) value. Second, perceived value has a significant mediate role in the effect of MGC on continuous following intention. Third, perceived value and continuous following intention significantly and sequentially mediated the effect of MGC on online purchase intention. Through the sequential mediations of perceived utility value and continuous following intention, Informational MGC of search products significantly increase online purchase intentions. Another parallel sequential mediation, including perceived hedonic, emotional MGC of experience products, partially enhanced online purchase intentions. Finally, this study gives implications for how corporates can use social media MGC to promote product sales online.

Research of reducing thermal stress generated in MGC turbine nozzles

  • Fujimoto, Syuu
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2004.03a
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    • pp.385-390
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    • 2004
  • An unique ceramic material produced through unidirectional solidification with eutectic composition of two-phase oxides was introduced recently. This composite material has the microstructure of coupled networks of two single crystals interpenetrate each other without grain boundaries. Depending on this microstructure this material, called Melt Growth Composite (MGC), can sustain its room temperature strength up to 1$700^{\circ}C$ (near its melting point) and offer strong oxidization-resistant ability, making its characteristics quite ideal for the gas turbine application. The research project on MGC started in 2001 with the objective of establishing component technologies for MGC application to the high temperature components of the gas turbine engine. MGC turbine nozzles are expected to improve efficiency of gas turbine. However, reduction of the thermal stress is required since high thermal stress is easily generated in MGC turbine nozzles due to temperature distribution. Firstly, the hollow nozzle shape was optimized to reduce thermal stress using numerical analysis. From the results of the first hot gas flow tests, the thermal stress due to span-wise temperature distribution was required to be reduced, and separated nozzle to three pieces was designed. This was tested in hot gas flow at 140$0^{\circ}C$ level, and temperature distributions on the nozzle surface were obtained and stress field was evaluated.

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Predictive Significance of Promoter DNA Methylation of Cysteine Dioxygenase Type 1 (CDO1) in Metachronous Gastric Cancer

  • Kubota, Yo;Tanabe, Satoshi;Azuma, Mizutomo;Horio, Kazue;Fujiyama, Yoshiki;Soeno, Takafumi;Furue, Yasuaki;Wada, Takuya;Watanabe, Akinori;Ishido, Kenji;Katada, Chikatoshi;Yamashita, Keishi;Koizumi, Wasaburo;Kusano, Chika
    • Journal of Gastric Cancer
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    • v.21 no.4
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    • pp.379-391
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    • 2021
  • Purpose: Promoter DNA methylation of various genes has been associated with metachronous gastric cancer (MGC). The cancer-specific methylation gene, cysteine dioxygenase type 1 (CDO1), has been implicated in the occurrence of residual gastric cancer. We evaluated whether DNA methylation of CDO1 could be a predictive biomarker of MGC using specimens of MGC developing on scars after endoscopic submucosal dissection (ESD). Materials and Methods: CDO1 methylation values (TaqMeth values) were compared between 33 patients with early gastric cancer (EGC) with no confirmed metachronous lesions at >3 years after ESD (non-MGC: nMGC group) and 11 patients with MGC developing on scars after ESD (MGCSE groups: EGC at the first ESD [MGCSE-1 group], EGC at the second ESD for treating MGC developing on scars after ESD [MGCSE-2 group]). Each EGC specimen was measured at five locations (at tumor [T] and the 4-point tumor-adjacent noncancerous mucosa [TAM]). Results: In the nMGC group, the TaqMeth values for T were significantly higher than that for TAM (P=0.0006). In the MGCSE groups, TAM (MGCSE-1) exhibited significantly higher TaqMeth values than TAM (nMGC) (P<0.0001) and TAM (MGCSE-2) (P=0.0041), suggesting that TAM (MGCSE-1) exhibited CDO1 hypermethylation similar to T (P=0.3638). The area under the curve for discriminating the highest TaqMeth value of TAM (MGCSE-1) from that of TAM (nMGC) was 0.81, and using the cut-off value of 43.4, CDO1 hypermethylation effectively enriched the MGCSE groups (P<0.0001). Conclusions: CDO1 hypermethylation has been implicated in the occurrence of MGC, suggesting its potential as a promising MGC predictor.

A Modified Generalized Chebyshev LPF Design with Improved Stopband (개선된 저지 대역을 갖는 변형된 일반화된 체비셰프 저역 통과 필터 설계)

  • Kim In-Seon;Kim Kwang-Soo;Lim Jong-Sik;Ahn Dal
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.16 no.11 s.102
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    • pp.1155-1163
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    • 2005
  • In this paper, we suggest the new method to considerably enlarge stopband without increment of filter sire and loss. The proposed low pass filter looks like outward configuration with the published Modified Generalized Chebyshev (MGC) low pass filter, but the element values completely differ from each other. The published MGC fille, had been considered only the second attenuation pole to reject(or suppress) the harmonic, whereas the stopband of the proposed filter is superior to the published MGC filter because not only the second attenuation pole but also the third harmonic of the first attenuation pole is made use of profitably. We fabricate a low pass filter according to the proposed theory. From the measurement of the fabricated filter, we can confirm that the stopband of the proposed filter is reached above 4 times wider than the conventional Generalized Chebyshev(GC) filter and above 1.7 times wider than the published MGC filter.

Marketer-Generated Content Sharing Among Social Broadcasting Users: Effects of Intrinsic Motivations, Social Capital and the Moderating Role of Prevention Focus

  • Li, Yuhao;Wang, Kanliang
    • Asia pacific journal of information systems
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    • v.25 no.4
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    • pp.719-745
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    • 2015
  • Social networking services provide individuals with an easy approach for exchanging messages with others based on interpersonal relationships. However, why individuals spread marketer-generated content (MGC) in their online social circles remains unclear. Therefore, we develop a theoretical model to examine how social capital, intrinsic motivations, personal perceptions, past behavior, and personal traits influence MGC sharing behavior of social media users in micro-blogging context. Data collected from 319 social networking users support the proposed model. The results from partial least squares analyses show that enjoyment, perceived control, and outcome expectations are significant indicators of individual's MGC sharing intention in the social broadcasting environment. Results also suggest that social capital, users' intention, and past behavior positively influence the MGC sharing behavior of users. Moreover, individual prevention pride exhibits a significant interaction effect on the relationships between users' MGC sharing and its antecedents. Implications for research and practice are discussed.

A Study on Routing Method between MGC for VoIP Service (VoIP 서비스를 위한 MGC 간 라우팅 방법에 관한 연구)

  • Kim, Eun-Joo;Lee, Byung-Sun
    • Proceedings of the Korea Information Processing Society Conference
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    • 2002.11b
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    • pp.1515-1518
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    • 2002
  • 인터넷 서비스의 수요가 급증함에 따라 통신서비스 제공기업에서도 VoIP 시스템 도입의 중요성이 부각되고 있다. PSTN 교환기는 호 처리 기능과 회선 스위칭 기능이 하나로 결합된 단일 시스템인 반면, VoIP 시스템에서의 MGC 는 하드웨어 부분과 소프트웨어 부분을 물리적으로 분리하고 둘 사이의 인터페이스를 표준 프로토콜을 적용한 것이다. 이때 MG(Media Gateway)는 회선 스위칭 기능을 담당하고 MGC(Media Gateway Controller)는 호 처리 기능을 수행한다. 최근 국내 외 업체들에서는 VoIP 시스템 제공이 시작되고 있으나 국내 IP 기반 통신서비스 제공업체에서는 VoIP 시스템 제공이 미흡한 실정이다. 본 논문에서는 VoIP 시스템에서 MGC 간 라우팅 방법을 최적화 함과 동시에 사용자들에게 다양한 서비스를 제공할 수 있는 라우팅 방안을 제시하고자 한다.

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A study on AX-Gateway System Design and Construction for Interfacing between MGCP and H.323 (MGCP 기반의 게이트웨이 시스템에서 다양한 MGC와의 호환성을 위한 기법)

  • Kang, Jae-Kyung;Kim, Hyeon-Gyu;Oh, Eun-Rog;Kang, Tae-Ik;Kim, Chul-Ju
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.27 no.1C
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    • pp.36-47
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    • 2002
  • MGCP ia standard protocol by IFTF, which is designed to facilitate inter-working with other protocols. Since the nature of protocol, it can be known as a proper solution to integrate heterogeneous networks consisted of various protocols and systems. In this paper MGCP is used for controlling VoIP gateways from external call control elements(MGCs) and introduces a method to improve interoperability for various MGC in a gateway based on MGCP. It presents implementation issues to provide the interoperability for MGC dependent parts such as call flows of message encoding, and a system architecture to resolve the issues.

Silibinin Inhibits Proliferation, Induces Apoptosis and Causes Cell Cycle Arrest in Human Gastric Cancer MGC803 Cells Via STAT3 Pathway Inhibition

  • Wang, Yi-Xin;Cai, Hong;Jiang, Gang;Zhou, Tian-Bao;Wu, Hai
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.16
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    • pp.6791-6798
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    • 2014
  • Background: To investigate the effect of silibinin on proliferation and apoptosis in human gastric cancer cell line MGC803 and its possible mechanisms. Materials and Methods: Human gastric cancer cell line MGC803 cells were treated with various concentration of silibinin. Cellular viability was assessed by CCK-8 assay andapoptosis and cell cycle distribution by flow cytometry. Protein expression and mRNA of STAT3, and cell cycle and apoptosis regulated genes were detected by Western blotting and real-time polymerase chain reaction, respectively. Results: Silibinin inhibits growth of MGC803 cells in a dose- and time-dependent manner. Silibinin effectively induces apoptosis of MGC803 cells and arrests MGC803 cells in the G2/M phase of the cell cycle, while decreasing the protein expression of p-STAT3, and of STAT3 downstream target genes including Mcl-1, Bcl-xL, survivin at both protein and mRNA levels. In addition, silibinin caused an increase in caspase 3 and caspase 9 protein as well as mRNA levels. Silibinin caused G2/M phage arrest accompanied by a decrease in CDK1 and Cyclin B1 at protein and mRNA levels.. Conclusions: These results suggest that silibinin inhibits the proliferation of MGC803 cells, and it induces apoptosis and causes cell cycle arrest by down-regulating CDK1, cyclinB1, survivin, Bcl-xl, Mcl-1 and activating caspase 3 and caspase 9, potentially via the STAT3 pathway.

Deodorizing Effect of Several Antibacterial Medicinal Herbs on Oral Malodor (항균작용을 가진 수종 한약재의 구취억제 효과)

  • Kim, Hyun-Kyung;Park, Jae-Woo;Yoon, Seong-Woo;Ryu, Bong-Ha;Kim, Jin-Sung
    • The Journal of Korean Medicine
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    • v.31 no.4
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    • pp.151-163
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    • 2010
  • Objective: We investigated the oral malodor inhibitory effect of Scutellariae Radix (SR), Phellodendri Cortex (PC), Moutan Cortex (MTC) and Magnoliae Cortex (MGC) for the development of a gargle solution. Methods: 1. Against P. gingivalis and Pr. intermedia, the minimal bactericidal concentration (MBC) and the change of viable cells that were exposed to 1% each herbal extract were observed. 2. Deodorizing activity of 2% herbal extract and Garglin $Mint^{(R)}$ against methyl mercaptan were evaluated by gas chromatography (GC). 3. We used the salivary sediment system (SSS) as the malodor model. 4. The clinical examination was repeated 3 times by 2 subjects by $Halimeter^{(R)}$. Baseline VSC of each subject was measured. Then, the control subject gargled with cysteine for 30 sec. After 4 min, subjects would gargle for 30 seconds with herbal extracts (2%) and Garglin $Mint^{(R)}$. Subsequently, the concentration of VSC was measured at 0, 4, 8, 12, 16, 20, 40 and 60 minutes. Results: 1. Against P. gingivalis, MBC of SR, PC and MTC was 0.1%, and MBC of MGC was 1%. Removal time of P. gingivalis was as follows; 5 hr in MGC, 24 hr in SR and PC, and 48 hr in MTC. Against Pr. intermedia, MBC of SR and PC was 0.5%, and MBC of MTC, MGC was 1%. Removal time of Pr. intermedia was as follows; 5 hr in MTC and 24 hr in SR, PC and MGC. 2. Deodorizing effect of herbal extracts against methyl mercaptan was as follows; MGC and MTC had 100%, SR had 82.22%, PC had 66.60%, Garglin $Mint^{(R)}$ had 40.54%. 3. In the experiment using SSS, PC and MTC had statistically significant malodor-inhibitory effects (p<.05). 4. In the clinical examination, PC and MGC had statistically significant inhibitory effects at every elapsed time compared to the control subject. MTC had that until 40 min. SR had that at 0, 4, 8, 20, and 60 min. Conclusions: SR, PC, MTC and MGC have an antibacterial effect and the chemical removable activity of the oral malodor caused by VSC. These four herbs could have potential as effective anti-malodor agents.

Effects of Celecoxib on Cycle Kinetics of Gastric Cancer Cells and Protein Expression of Cytochrome C and Caspase-9

  • Wang, Yu-Jie;Niu, Xiao-Ping;Yang, Li;Han, Zhen;Ma, Ying-Jie
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.4
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    • pp.2343-2347
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    • 2013
  • Objective: This investigation aimed to determine effects of celecoxib on the cell cycle kinetics of the gastric cancer cell line MGC803 and the mechanisms involved by assessing expression of cytochrome C and caspase-9 at the protein level. Methods: Cell proliferation of MGC803 was determined by MTT assay after treatment with celecoxib. Apoptosis was assessed using fluorescence staining and cell cycle kinetics by flow cytometry. Western blotting was used to detect the expression of caspase-9 protein and of cytochrome C protein in cell cytosol and mitochondria. Results: Celecoxib was able to restrain proliferation and induce apoptosis in a dose- and time-dependent manner, inducing G0/G1 cell cycle arrest, release of cytochrome C into the cytosol, and cleavage of pro-caspase-9 into its active form. Conclusion: Celecoxib can induce apoptosis in MGC803 cells through a mechanism involving cell cycle arrest, mitochondrial cytochrome C release and caspase activation.