• Journal of the Korean Institute of Telematics and Electronics S
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• v.36S no.5
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• pp.78-87
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• 1999

3차원 물체 인식은 학습에 의해서 구성된 모델베이스를 이용하여 주어진 입력 영상에 존재하는 한 개 혹은 여러 개의 물체를 구별하는 과정이다. 본 논문에서는 입력 거리 정보를 받아들여 이 정보로부터 보이는 각 면에 대한 특징을 추출해낸 후 이 특징들을 입력 영상에 존재하는 물체를 묘사하는 특징으로 사용하여 이로부터 모델을 결정하는 방법을 제시한다. 영상 분할된 입력 물체는 그래프로 표현되는데, 물체 인식은 입력 물체의 그래프를 모델 베이스의 각 모델의 그래프와 정합하는 고정에서 얻어진다. 제한 조건은 만족시키는 정합을 수행하기 위하여 mean field annealing (MFA) 신경 회로망을 사용하였으며 가려진 물체 인식을 수행할 수 있는 정합을 위해 에너지 함수를 제안하였다. 제안한 알고리듬의 효용성을 입증하기 위하여 가려짐의 정도를 다르게 한 합성영상에 대해서 모의 실험을 하였다.

• Bulletin of the Korean Chemical Society
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• v.26 no.1
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• pp.85-90
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• 2005

MX and its analogs are synthesized and modeled by quantitative structure activity relationship (QSAR) study including comparative molecular field analysis (CoMFA). As a result, factors affecting this class of compounds have been found to be steric and electrostatic effects. Because hologram quantitative structure activity relationship (HQSAR) technique is based on the 2-dimensional descriptors, this is free of ambiguity of conformational selection and molecular alignment. In this study we tried to include all the data available from the literature, and modeled with the HQSAR technique. Among the parameters affecting fragmentation, connectivity was the most important one for the whole compounds, giving good statistics. Considering additional parameters such as bond specification only slightly improved the model. Therefore connectivity has been found to be the most appropriate to explain the mutagenicity for this class of compounds.

• Journal of Institute of Control, Robotics and Systems
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• v.11 no.10
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• pp.823-829
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• 2005

We have newly constructed an in silico model of fermentative metabolism for Lactococcus lactis in order to analyze the characteristics of metabolite flux for dynamic network. A rigorous mathematical model for metabolic flux has been developed and simulation researches have been performed by using GEPASI program. In this simulation task, we were able to predict the whole flux distribution trend for lactate metabolism and analyze the flux ratio on the pyruvate branch point by using metabolic flux analysis(MFA). And we have studied flux control coefficients of key reaction steps in the model by using metabolic control analysis(MCA). The role of pyruvate branch seems to be essential for the secretion of lactate and other organic byproducts. Then we have made an effort to elucidate its metabolic regulation characteristics and key reaction steps, and find an optimal condition for the production of lactate.

• Proceedings of the Korea Information Processing Society Conference
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• 2001.10a
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• pp.585-588
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• 2001

현실 세계의 많은 조합 최적화 문제들은 변수들이 강하게 상호 작용함에 따라 만족해야하는 목표 함수가 매우 복잡하게 주어진다. 복잡한 목표 함수에는 많은 지역 최적해들이 존재하기 때문에 전역 최적해를 얻는 것은 엄청난 시간을 필요로 한다. 이러한 문제에 대해 해를 찾는 방법의 하나로 평균장 어닐링 알고리즘(MFA)이 있다. 본 논문에서는 기존의 이진 상태 공간에만 적용할 수 있었던 평균장 어닐링 알고리즘을 연속 상태 공간을 갖는 조합 최적화 문제에 적용할 수 있도록 알고리즘을 수정, 제안한다. 그리고 제안된 알고리즘을 제한된 연속 상태 공간을 가지는 단순 회귀 모델의 D-최적 설계에 적용하였다. 실험결과 제안된 알고리즘이 시뮬레이티드 어닐링 알고리즘(SSA)과 비교하여 비슷한 수준의 결과를 내면서도 계산 속도면에서는 수 배 정도의 빠른 좋은 결과를 얻었다.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.21 no.7
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• pp.380-385
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• 2009

This study is to investigate the pressure wave characteristics and the maximum pressure rise generated by instantaneous valve closure at the end of the straightening polybutylene double piping system with header. Experiments were conducted under the following conditions: initial pressure $0.1{\sim}0.5$ MFa, flow velocity $0.5{\sim}3.0$ m/s and water temperature $25^{\circ}C$.

• Journal of Integrative Natural Science
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• v.5 no.1
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• pp.1-5
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• 2012

Quantitative structure-activity relationship (QSAR) methodologies have been applied for many years, to correlate the relationship between physicochemical properties of chemical substances and their biological activities to generate a statistical model for prediction of the activities of new chemical entities. The basic principle behind the QSAR models is that, how structural variation is responsible for the difference in biological activities of the compounds. 3D-QSAR has emerged as a natural extension to the classical Hansch and Free-Wilson approaches, which develops the 3D properties of the ligands to predict their biological activities using various chemometric techniques (PLS, G/PLS, ANN etc). It has served as a valuable predictive tool in the design of pharmaceuticals and agrochemicals. This review seeks to provide different 3D-QSAR approaches involved in drug designing process to develop structure-activity relationships and also discussed the fundamental limitations, as well as those that might be overcome with the improved methodologies.

• Annual Conference on Human and Language Technology
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• 2023.10a
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• pp.14-18
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• 2023

본 연구는 한국어 음성-텍스트 데이터에서 보편적으로 나타난 휴지의 실현 양상을 분석하고, 이를 토대로 데이터셋을 선별해 보편적이고 규격화된 한국어 휴지 예측을 위한 모델을 제안하였다. 이를 위해 전문적인 발성 훈련을 받은 성우 등의 발화가 녹음된 음성-텍스트 데이터셋을 수집하고 MFA와 같은 음소 정렬기를 사용해 휴지를 라벨링하는 등의 전처리를 하고, 다양한 화자의 발화에서 공통적으로 나타난 휴지를 선별해 학습데이터셋을 구축하였다. 구축된 데이터셋을 바탕으로 LLM 중 하나인 KULLM 모델을 미세 조정하고 제안한 모델의 휴지 예측 성능을 평가하였다.

• Applied Biological Chemistry
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• v.51 no.3
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• pp.171-176
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• 2008

The comparative molecular similarity indices analysis (CoMSIA) models between 3${\beta}$-Hydroxy-12-oleanen-28-oic acid (1-30) analogues as substrate molecule and their inhibitory activities ($pI_{50}$) against protein tyrosine phosphatase (PTP)-1B were derived and discussed quantitatively. Listing in order, the CoMFA>CoMSIA${\geq}$HQSAR>2D-QSAR model, these QSAR models had the better statistical values. The optimized CoMSIA F1 model at grid 3.0${\AA}$ had the best predictability and fitness ($q^2$=0.754 and $r^2$=0.976) by field fit alignment. The order of contribution ratio (%) of CoMSIA fields concerning the inhibitory activities was a H-bond acceptor (48.9%), steric field (25.8%) and hydrophobic field (25.4%), respectively. Therefore, the inhibitory activities of substrate molecules against PTP-1B were dependent upon H-bond acceptor field (A) of $R_4$-group. From the analytical results of CoMSIA contour maps, oleanolic acid derivatives will have better inhibition activities if $R_1$ group has H-bond acceptor disfavor, $R_3$group has steric disfavor and $R_4$ group has steric, hydrophobic, H-bond favor.

• The Korean Journal of Applied Statistics
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• v.31 no.3
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• pp.315-328
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• 2018

In this paper, we examine the methodology to predict consumer preferences using several groups of attributes of products and application to real data. In the food industry, studies are in progress to investigate the relationship between product attributes and consumer preferences; consequently, various methodologies are proposed. Among these methodologies, we consider multiple factor analysis (MFA). The result of the MFA enable the division of consumers into four clusters with similar liking and the defining of preference characteristics for each cluster. Also, using the results of multiple factor analysis, we find the partial least squares path model to predict consumer preferences through the characteristics of the product and the characteristics evaluated by consumers. We can understand the relationship between the cluster of consumers and the preferred/undesirable characteristics of products through the partial least squares path model applied to two clusters with different liking. When multiple factor analysis is used in the partial least squares path model, it is possible to investigate relationships between products and consumers by analyzing product characteristics and consumer preferences simultaneously. The results can be applied to product developments and sales which makes this methodology important and useful.

• Economic and Environmental Geology
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• v.39 no.5 s.180
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• pp.615-626
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• 2006

The natural resources and material life-cycle include all human activities related to resources and material extraction, transportation, processing, use, recovery and disposal. Sustainable material management (SMM) is an integrated set of policy approaches targeted on economic agents throughout the material life-cycles and designed to result in economically efficient and environmentally effective material use. The material flows of industrial mineral, ores and fossil fuels have also long been a focal area for environmental policies because of the high environmental pressures associated with extraction, processing, consumption, and final disposal of these materials. OECD work on material flow is to improve the quantitative and analytical knowledge bases about natural resource and material flows within and among countries, so as to better understand the importance of material resources in member countries' economies. In several EU Member States, material flow accounts are part of official statistics. Material flow analysis (MFA) is a valuation method which assesses the efficiency of use of materials using information from material flow accounting. Material flow analysis helps to identify waste of natural resources and other materials in the economy which would otherwise go unnoticed in conventional economic monitoring systems. Resource use and resource efficiency has emerged as a major issue for long-term sustainability and environmental policy.