• Title/Summary/Keyword: MET1

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Inhibition of Human Hemoglobin Autoxidaiton by Sodium n-Dodecyl Sulphate

  • Reza, Dayer Mohammad;Ali Akbar, Moosavi-Movahedi;Parviz, Norouzi;Ghourchian, Ghourchian;Hedayat-Olah, Hedayat-Olah;Shahrokh, Safarian
    • BMB Reports
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    • v.35 no.4
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    • pp.364-370
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    • 2002
  • The effect of sodium n-dodecyl sulphate (SDS) on hemoglobin autoxidation was studied in the presence of a 100mM phosphate buffer (pH 7.0) by different methods. These included spectorphotometry, fluorescence technique, cyclic voltametry, differential scanning calorimetry, and densitometry. Spectroscopic studies showed that SDS concentrations up to 1 mM increased deoxy-, decreases oxy-, and had no significant effect on the met- conformation of hemoglobin. Therefore, a SDS concentration up to 1 mM increased the deoxy form of hemoglobin as the folded, compact state and decreases the oxy conformation. The turbidity measurements and differential scanning calorimetry techniques indicated a more stable conformation for hemoglobin in the presence of SDS up to 1mM. Electrochemical studies also confirmed a more difficult oxidation under these conditions. The induction of the deoxy form in the presence of SDS was confirmed by densitometry techniques. The compact structure of deoxyhemoglobin blocks the formation of met-conformation in low SDS concentrations.

Associations between Health Behaviors and Health-Related Quality of Life among Breast Cancer Survivors

  • Kim, Soo-Hyun;Yun, Young-Ho
    • Asian Oncology Nursing
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    • v.12 no.1
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    • pp.12-19
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    • 2012
  • Purpose: To examine the levels of physical activity (PA) and diet quality, socio-demographic and clinical correlates, and identify associations with health-related quality of life (HRQOL) among breast cancer survivors. Methods: The study used a cross-sectional study design. A total of 74 breast cancer survivors who had completed their primary cancer therapy were recruited from a comprehensive cancer center in Korea. Measurements used included the International Physical Activity Questionnaire, the Diet Quality Index, and the EORTC QLQ-C30. Results: Only twenty-six women (35.1%) met the American Cancer Society criteria of weekly PA, while most participants (93.2%) displayed good or excellent diet quality. Those less likely to meet the PA criteria were older women, women who had a lower economic level, and women not receiving anti-hormone therapy. However, there was no significant factor associated with diet quality. Women who met the criteria for PA displayed significantly better global QOL than women who did not meet the criteria. No significant differences were found in HRQOL between women who did and did not meet the diet quality criteria. Conclusion: Nurses should be aware of breast cancer survivors who are older and who have a low economic status when assessing and screening the level of PA to improve HRQOL.

Comparing Physical and Thermal Environments Using UAV Imagery and ENVI-met (UAV 영상과 ENVI-met 활용 물리적 환경과 열적 환경 비교)

  • Seounghyeon KIM;Kyunghun PARK;Bonggeun SONG
    • Journal of the Korean Association of Geographic Information Studies
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    • v.26 no.4
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    • pp.145-160
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    • 2023
  • The purpose of this study was to compare and analyze diurnal thermal environments using Unmanned Aerial Vehicles(UAV)-derived physical parameters(NDVI, SVF) and ENVI-met modeling. The research findings revealed significant correlations, with a significance level of 1%, between UAV-derived NDVI, SVF, and thermal environment elements such as S↑, S↓, L↓, L↑, Land Surface Temperature(LST), and Tmrt. In particular, NDVI showed a strong negative correlation with S↑, reaching a minimum of -0.52** at 12:00, and exhibited a positive correlation of 0.53** or higher with L↓ at all times. A significant negative correlation of -0.61** with LST was observed at 13:00, suggesting the high relevance of NDVI to long-wavelength radiation. Regarding SVF, the results showed a strong relationship with long-wave radiative flux, depending on the SVF range. These research findings offer an integrated approach to evaluating thermal comfort and microclimates in urban areas. Furthermore, they can be applied to understand the impact of urban design and landscape characteristics on pedestrian thermal comfort.

Breeding of Yeast Strain with Starch Utilizing and Alcohol Fermenting Ability by Protoplast Fusion (전분분해활성과 알코올 발효능을 보유한 효모의 육종)

  • Ju, Min-No;Hong, Sung-Wook;Kim, Kwan-Tae;Yum, Sung-Kwan;Kim, Gye-Won;Chung, Kun-Sub
    • Microbiology and Biotechnology Letters
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    • v.36 no.2
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    • pp.158-164
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    • 2008
  • The fusants which contain starch utilizing ability and alcohol fermenting ability were developed by protoplast fusion of Saccharomyces cerevisiae KOY-1 and Saccharomyces diastaticus KCTC 1804. Sacharomyces cerevisiae KH-12 was obtained by haploid induction from Saccharomyces cerevisiae KOY-1. The auxotropic mutants of yeast were obtained by using an ethylmethane sulfonate (EMS). The frequency of protoplast formation in Saccharomyces cerevisiae KOY-1 $(Met^-)$ and Saccharomyces diastaticus KCTC 1804 $(Trp^-)$ were 90.5% and 97.7%, respectively. The frequency of fusant formation was $1.79{\times}10^{-4 }$ for the regenerated protoplast and the 1,000 fusants were obtained. Fusant FA 776 was selected as a potential yeast which contain an alcohol fermenting ability in the starch medium. The genetic stability was 4.64% for 10 passages of generation. Fusant FA 776 produced 13mg/ml of alcohol in 24% starch medium and showed 1.86-fold higher alcohol fermenting ability than Saccharomyces diastaticus KCTC 1804.

The Microstructures and Properties of Surface Layer on the Tool Steel Formed by Ion Nitriding -Effects of Process Parameter- (마이크로 펄스 플라즈마 질화에 의해 생성된 금형 공구강의 표면층에 관한 연구 -공정 변수의 영향-)

  • Lee, J.S.;Kim, H.G.;You, Y.Z.
    • Journal of the Korean Society for Heat Treatment
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    • v.14 no.1
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    • pp.8-16
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    • 2001
  • The effects of gas composition, pressure, temperature and time on the case thickness, hardness and nitride formation in the surface of tool steels(STD11 and STD61) have been studied by micro-pulse plasma nitriding. External compound layer and internal diffusion layer and the diffusion layer were observed in the nitrided case of tool steels. The relative amounts and kind of phases formed in the nitrided case changed with the change of nitriding conditions. Generally, only nitride phases such as ${\gamma}(Fe_4N)$, ${\varepsilon}(Fe_{2-3}N)$, or $Cr_{1.75}V_{0.25}N_2$ phases were detected in the compound layer, while nitride and carbide phases such as ${\varepsilon}-nitride(Fe_{2-3}N)$, $(Cr,Fe)_{\gamma}C_3$ or $Fe_3C$ were detected in the diffusion layer by XRD analysis. The thickness of compound layer increased with the increase of nitrogen content in the gas composition. Maximum case depth was obtained at gas pressure of 200Pa.

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The Clinical Studies for Muscle Energy Techniques on Patients with Nuchal Pain Caused by Traffic Accidents (교통사고로 유발된 경항통 환자의 근에너지기법(MET)의 효과에 대한 임상적 연구)

  • Jeon, Tae-Dong;Lee, Han-Gil;Hong, Seo-Yuong;Heo, Dong-Seok;Yoon, Il-Ji
    • Journal of Korean Medicine Rehabilitation
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    • v.19 no.1
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    • pp.125-134
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    • 2009
  • Objectives : The purpose of this study is to find out the effects of muscle energy techniques on nuchal pain caused by traffic accidents. Methods : The 20 patients were divided into 2 groups: group A was treated except muscle energy techniques and group B was treated with muscle energy techniques. Both groups were treated with acupunture treatment, physical theraphy and herbal medication. Patients were evaluated by McGill Pain Questionnaire-Short Form(SF-MPQ), Pain Disability Index(PDI) and Neck Disability Index(NDI) in traffic accident patients. Results : 1. Both Group were significantly decreased in sensory of SF-MPQ, VAS, PDI and NDI after 7 days of treatment. 2. Group B compared with the Group A was significantly decresed in VAS, PDI after 7 days of treatment. Conclusions : We found out that muscle energy techniques is considered to be effective and useful on nuchal pain caused by traffic accidents.

Quality Inspection to the Ginseng Saponins in Commercial Ginseng-extracts (인삼(人蔘)사포닌을 중심(中心)한 인삼정(人蔘精)의 품질조사(品質調査))

  • Cho, Kyu-Seong;Kim, Hai-Jung;Joo, Hyun-Kyu
    • Korean Journal of Pharmacognosy
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    • v.12 no.4
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    • pp.185-189
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    • 1981
  • The quality inspection was made on commercial Korean ginseng extract (Company A, B, C, D, E, F, G and H), particularly on samples available in Seoul market area. The results were as follews: 1) Among the ginseng extract products out of eight different manufactures, the moisture content of D company's product showed 46.5%, and other companys' met with the moisture standard for ginseng extracts. And protein, fat, ash, fiber and total sugar were about $9.87{\sim}21.07%,\;0.46{\sim}1.62%,\;6.55{\sim}7.88%,\;0{\sim}0.15%\;and\;58.58{\sim}76.74%$, respectively. And residue of D and F company products showed 3.25% and 3.61% which exceed the standard, and other company products met with residue test specifications. 2) The contents of ginseng saponins were 16.16% and 13.12%, respectively, for the C and H company products. However, other company's showed below 9%. By fractional distribution of ginseng saponins, it is supposed to be white ginseng and lateral ginseng that were mostly used as raw materials for ginseng extract manufacturing.

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The Determinants of Propensity To Stay Among Hospital Nurses (병원간호직 근무자의 근속성향 결정요인)

  • Seo, Young-Joon;Ko, Jong-Wook
    • Korea Journal of Hospital Management
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    • v.2 no.1
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    • pp.137-161
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    • 1997
  • This study purports to investigate the determinants of propensity to stay among nursing staff working at Korean hospitals. The independent variables contains three groups of determinants: environmental variables(job opportunity, spouse support, and parent support), psychological variables(met expectations, work involvement, positive affectivity, and negative affectivity), and structural variables(job autonomy, work unit control. routinization, supervisor support, coworker support, role ambiguity, role conflict, workload, resource inadequacy, distributive justice, promotional chances. job security, job hazards, and pay). The sample used in this study consisted of 329 nurses and 175 nurse aides from two university hospitals in Seoul and its surburbs. Data were collected with self-administered questionnaires and analyzed using path analysis. The results of this study indicate that: (1) the following variables, listed in order of size, have significant positive effects on propensity to stay among hospital nursing staff: job satisfaction, met expectations, supervisor support, job security, and positive affectivity, (2) the following variables, listed in order of size, have significant negative total effects on propensity to stay among hospital nursing staff: job opportunity, negative affectivity, and rutinization, (3) the model explains 44.2 percent of the variance in propensity to stay among nursing staff working at two university hospitals, and (4) managerial support for improving the job autonomy, distributive justice, and promotional opportunity for nurse aides are needed.

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The Study of the Veneer Pretreatment with Aluminum Sulfate Solution on the Reduction of Urea Formaldehyde Resin Spreading Content for the Manufacture of Plywood (황산알미늄용액의 단판(單板) 전처리(前處理)에 따른 합판용(合板用) 요소수지(尿素樹脂) 도포량의 감소에 관한 연구(硏究))

  • Lee, Hwa-Hyoung
    • Journal of the Korean Wood Science and Technology
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    • v.16 no.1
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    • pp.3-8
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    • 1988
  • This study was carried out to examine the effect of pretreatment of veneer with aluminum sulfate solution for the manufacture of the kapur plywood on the reduction of urea resin spread. The results were as follows: 1. Specific gravities of plywoods made of the kapur veneers ranged from 0.83 to 0.84 and their moisture contents based on air dry weight showed from 10.6% to 11.4%. These met the Korean Industrial Standards. 2. In the case of dry shear strength for the 3rd class plywood, 40% reduction- spread met K S as well as normal urea resin spread. pH of the aluminum sulfate solution gave better result at pH 4.5 and pH 6 than at pH 3. For the manufacture of the 2nd class plywood, hot and cold water-wet shear strength show the best results at the following conditions; such as 20% reduction spread, pH 4.5 of aluminum sulfate solution and all veneer treatment.

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