• Journal of Animal Science and Technology
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• v.50 no.3
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• pp.355-362
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• 2008

This study was carried out to evaluate effects of either organic or inorganic sources of both chromium and copper on growth performances, nutrients digestibility and fecal Cr, Cu, and Zn excretion in growing pigs. A total of 36 growing pigs((Landrace×Yorkshire)×Duroc, weighing 61.2kg in average) were allotted to 4 treatments with 3 replicates and 3 pigs per replicate. Four treatments were designated by supplemental sources of both chromium and copper as follows: ①200ppb Cr as Cr-methionine chelate(CrMet) and 200ppm Cuas copper methionine chelate(CuMet), ②200ppb Cr as CrMet and 200ppm Cu as copper sulfate(CuSO4), ③200ppb Cr as chromium chloride(CrCl3) and 200ppm Cu as CuMet, ④200ppb Cr as CrCl3 and 200ppm Cu as CuSO4. Growth performance was highest(p<0.05) in CrMet and CuMet supplemented diet treatment. Nutrients digestibility of diets was lowest(p<0.05) in CrMet and CuSO4 supplemented diet treatment, and highest(p<0.05) in CrMet and CuMet supplemented diet treatment. Fecal copper, zinc and chromium excretion was highest(p<0.05) in CrCl3 and CuSO4 supplementation treatment and lowest(p<0.05) in CrMet and CuMet supplementation treatment. This study showed a relatively high degree of utilization of Cr and Cu as well as Zn by supplementation of CrMet and CuMet compared with those of the inorganic sources.

• 한국신재생에너지학회:학술대회논문집
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• 2011.11a
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• pp.35.1-35.1
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• 2011

When the wind speed is measured by the met-mast sensor it is distorted due to the shadow effect of tower. In this paper the tower shadow effect is analyzed by a computational fluid dynamics code. First three dimensional modeling and flow analysis of the met-mast system were performed. The results were compared with the available experimental wind-tunnel test data to confirm the validity of the meshes and turbulence model. Two-dimensional model was then developed based on the three-dimensional works and experimental data. 2D analysis for various Reynolds numbers and turbulence strengths were then performed to establish the tower shadow effect database, which can be utilized as correction factors for the measured wind energy.

• Elastomers and Composites
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• v.16 no.1
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• pp.3-13
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• 1981

The purpose of this dissertation is to study the physical properties of cellular rubber products for industrial use. Vulcanization characteristics were investigated by usingcure curve that had obtained by means of Rheometer. The results of physical properties, vulcanization characteristics and foaming states are as follows. 1. The test results for vulcanization characteristics of NR compounds indicated that in the recipe R-1. When accelerator D is used, the optimum conditions of vulcanizate are obtained, while formula R-2 and R-3 have shown higher torgue at curing time, $1{\sim}2$ minutes. Cellular rubber product test in terms of compression set and compression deflection has also met the requirements of SAE. 2. For SBR compounds, S-1 formula was the best in terns of vulcanization characteristics, and for the blowing structure of cellular rubber products, formula S-3 in which accelerator M is added was fair. All other test results, such as compression set and compression deflection properties met SAE requirements. 3. NBR compound (N-1) including accelerator TT was the best in terms of vulcanization characteristic and also blowing structure. All other properties listed above met requirements, particulary for oil resistance test. 4. In the test of EPDM compounds, when mixed accelerator, M and TT, is used(formula E-1) the best results were obtained. Since EPDM is hydrocarbon elastomer, oil resistance test failed. All other properties met the requirement specified in SAE.

• Animal cells and systems
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• v.2 no.1
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• pp.1-8
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• 1998

Hepatocyte growth factor (HGF), originally discovered and cloned as a powerful mitogen for hepatocytes, is a four kringle-containing growth factor which specifically binds to membrane-spanning tyrosine kinase, c-Met/HGF receptor. HGF has mitogenic, motogenic (enhancement of cell movement), morphogenic (e.g., induction of branching tubulogenesis), and anti-apoptotic activities for a wide variety of cells. During embryogenesis, HGF supports organogenesis and morphogenesis of various tissues, including liver, kidney, lung, gut, mammary gland, and tooth. In adult tissues HGF elicits an organotrophic function which supports regeneration of organs such as liver, kidney, lung, and vascular tissues. HGF is also a novel member of neurotrophic factor in nervous systems. Together with the preferential expression of HGF in mesenchymal or stromal cells, and c-Met/HGF receptor In epithelial or endothelial cells, the HGF-Met coupling seems to orchestrate dynamic morphogenic processes through epithelial-mesenchymal (or-stromal) interactions for organogenesis and organ regeneration. HGF or HGF gene may well become unique therapeutic tools for treatment of patients with various organ failure, through its actions to reconstruct organized tissue architectures. This review focuses on recently characterized biological and physiological functions integrated by HGF-Met coupling during organogenesis and organ regeneration.

• Journal of Pharmaceutical Investigation
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• v.24 no.1
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• pp.1-9
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• 1994

In order to study systemic peptide delivery through the ocular route, the stabilities of methionine enkephalin (Met-Enk) and $[D-ala^2]-methionine$ enkephalinamide (YAGFM) in the corneal extracts of rabbits were investigated using reversed phase HPLC. Met-Enk was found to be hydrolyzed most rapidly in the corneal epithelium, but YAGFM was relatively stable. Aminopeptidases appeared to contribute over 60% to the degradation of Met-Enk and the degradation rate of Met-Enk followed the first order kinetics. The half-lives of Met-Enk in the extracts of the corneal epithelium and endothelium were 36 and 673 min, respectively. From the effects of enzyme inhibitors, it was found that the application of the mixture of amastatin, thimerosal and EDTA was very useful for the inhibition of peptide degradation.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.8
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• pp.3873-3877
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• 2012

Objective: Colorectal cancer (CRC) and the metabolic syndrome (MetS) are both on the rise in Malaysia. A multi-centric case-control study was conducted from December 2009 to January 2011 to determine any relationship between the two. Methods: Patients with confirmed CRC based on colonoscopy findings and cancer free controls from five local hospitals were assessed for MetS according to the International Diabetes Federation (IDF) definition. Each index case was matched for age, gender and ethnicity with two controls (140: 280). Results: MetS among cases was highly prevalent (70.7%), especially among women (68.7%). MetS as an entity increased CRC risk by almost three fold independently (OR=2.61, 95%CI=1.53-4.47). In men MetS increased the risk of CRC by two fold (OR=2.01, 95%CI, 1.43-4.56), demonstrating an increasing trend in risk with the number of Mets components observed. Conclusion: This study provides evidence fora positive association between the metabolic syndrome and colorectal cancer. A prospective study on the Malaysian population is a high priority to confirm these findings.

• Nutrition Research and Practice
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• v.6 no.1
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• pp.68-77
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• 2012

Flavan-3-ols are a subclass of flavonoids found in a variety of foods including teas. The effects of flavan-3-ols on the risk of metabolic syndrome (MetS) have been investigated, generally focusing on tea catechins or individual flavan-3-ol rich foods, but there is little information on dietary flavan-3-ols intake and risk of MetS in population-based studies. In this cross-sectional study, we examined the association between dietary flavan-3-ols intake and the risk of MetS in Korean adults. Subjects comprised 1,827 men and 2,918 women aged 20-69 years whose data was included in the 2008 Korean National Health and Nutrition Examination Survey. This survey was conducted between January 2008 and December 2008. Total flavan-3-ols intakes were calculated from 24-hour dietary recalls using a flavonoids database. Thirty percent of the male subjects and 24% of the female subjects were reported as having MetS. In the female subjects, flavan3-ols intake was inversely associated with the risk of MetS after adjusting for potential confounders (5th vs. 1st quintile, OR=0.64, 95% CI=0.45-0.91, P for trend=0.384). The main food source of flavan-3-ols was green tea followed by apples and grapes. Among MetS components, flavan-3-ols intake was inversely associated with the risk of high blood pressure after adjusting for potential confounders (5th vs. 1st quintile, OR=0.64, 95% CI=0.45-0.90, P for trend=0.005). No significant association between flavan-3-ols intake and risk of MetS was found in the male subjects. After stratified analysis by obesity (BMI ${\geq}$ 25 or BMI < 25), however, flavan3-ols intake was inversely related to the risk of hypertension in non-obese men. These results suggest that dietary flavan-3-ols intake may have beneficial effects on MetS risk by reducing the risk of hypertension. The effects of flavan-3-ols intake dependent on obesity need further investigation.

• Journal of Biosystems Engineering
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• v.4 no.1
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• pp.76-86
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• 1979

This study was conducted to find out the effects of rainfall occurring during the paddy sun-during process of traditional paddy harvesting operations on the quality of milld rice. Rice varieties used for the experiment were MINEHIJARI variety a japonica and SUWEON 264 vareity , a sister-line of TONG-IL . Sun-drying days after the paddy cutting, times of storm occurrance during sun-drying period, and storm duration were treated as variables. The results is summarised as follows : 1. Brown rice recovery exposed to rainfall during the sun-druing period were ranged 81.6-82.1% and 79.4-80.2% for MINEHIKARI and SUWEON 264 varieties, respectively. which showed negligible effect by rainfall. 2. Milling recovery of MINEHIKARI variety was not affected by storm duration but by the by the sun-drying days after cutting as the sun-drying days increased to eight and four days when the variety met the rainfall one and two times, respectively. The range of milling recoveries of MINEHIKARI variety were 75.18-74.07% and 75.24-73.46% as the variety met the rainfall one and two times, respectively, and it were estimated that up to 0.9% and 1.5% of milling recovery would be reduced by one and two times of rainfall during sun-drying period. 3. The milling recovery of SUWEON 264 variety was affected only by the increase of drying days after cutting when it met one time of rainfall during the sun-drying period, while it was begun to reduce by the storm duration more than 11hours as the drying paddy met two times of rainfall. The milling reveries of the paddy met one and two times of rainfall were ranged 74.24-73.21% and 74.02-72.36% which were estimated to be reduced up to 0.9 % and 1.8% by the increase of the drying days after cutting and storm duration , respectively. 4. The head rice recovery of MINEHIKARI rice variety showed notable decrease as the drying days after cutting increased, and also it was greatly reduced even by the five hours of storm duration when one time of rainfall occurred but it was not affected by storm duration when the rainfall occurred two times. Head rice recoveries of MINEHIKARI met one and two times of rainfall during the sun-drying period were 65. 15 -40.85% and 61.86 - 30.03 %, which showed terrible reduction as much as up to 25% and 35% compared to that which did not met rainfall during the sun-drying process. 5. Head rice recovery or SUWEON 264 variety was very much reduced as the sum-drying days after cutting increased. Storm duration less than five hours during the sun-drying process did not affect on the decrease of head rice recovery when the variety was exposed to one time of rainfall, while storm duration affected considerably on the reduction of head rice recovery of SUWEON 264 variety exposed to two times of rainfall. The range of head rice recovery, 56.43 - 33.94% and 51.28 - 21.03% , for the paddy exposed to rainfall one and two times were evaluated that up to 24% and 37% of reduction in head rice recovery would be brought about compared to the head rice recovery of the sundriedpaddy that did not met the rainfall.

• Journal of Biosystems Engineering
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• v.4 no.1
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• pp.75-75
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• 1979

This study was conducted to find out the effects of rainfall occurring during the paddy sun-during process of traditional paddy harvesting operations on the quality of milld rice. Rice varieties used for the experiment were MINEHIJARI variety a japonica and SUWEON 264 vareity , a sister-line of TONG-IL . Sun-drying days after the paddy cutting, times of storm occurrance during sun-drying period, and storm duration were treated as variables. The results is summarised as follows : 1. Brown rice recovery exposed to rainfall during the sun-druing period were ranged 81.6-82.1% and 79.4-80.2% for MINEHIKARI and SUWEON 264 varieties, respectively. which showed negligible effect by rainfall. 2. Milling recovery of MINEHIKARI variety was not affected by storm duration but by the by the sun-drying days after cutting as the sun-drying days increased to eight and four days when the variety met the rainfall one and two times, respectively. The range of milling recoveries of MINEHIKARI variety were 75.18-74.07% and 75.24-73.46% as the variety met the rainfall one and two times, respectively, and it were estimated that up to 0.9% and 1.5% of milling recovery would be reduced by one and two times of rainfall during sun-drying period. 3. The milling recovery of SUWEON 264 variety was affected only by the increase of drying days after cutting when it met one time of rainfall during the sun-drying period, while it was begun to reduce by the storm duration more than 11hours as the drying paddy met two times of rainfall. The milling reveries of the paddy met one and two times of rainfall were ranged 74.24-73.21% and 74.02-72.36% which were estimated to be reduced up to 0.9 % and 1.8% by the increase of the drying days after cutting and storm duration , respectively. 4. The head rice recovery of MINEHIKARI rice variety showed notable decrease as the drying days after cutting increased, and also it was greatly reduced even by the five hours of storm duration when one time of rainfall occurred but it was not affected by storm duration when the rainfall occurred two times. Head rice recoveries of MINEHIKARI met one and two times of rainfall during the sun-drying period were 65. 15 -40.85% and 61.86 - 30.03 %, which showed terrible reduction as much as up to 25% and 35% compared to that which did not met rainfall during the sun-drying process. 5. Head rice recovery or SUWEON 264 variety was very much reduced as the sum-drying days after cutting increased. Storm duration less than five hours during the sun-drying process did not affect on the decrease of head rice recovery when the variety was exposed to one time of rainfall, while storm duration affected considerably on the reduction of head rice recovery of SUWEON 264 variety exposed to two times of rainfall. The range of head rice recovery, 56.43 - 33.94% and 51.28 - 21.03% , for the paddy exposed to rainfall one and two times were evaluated that up to 24% and 37% of reduction in head rice recovery would be brought about compared to the head rice recovery of the sundriedpaddy that did not met the rainfall.

• Korean Journal of Clinical Laboratory Science
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• v.44 no.3
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• pp.147-154
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• 2012

Metabolic syndrome and homocysteine are associated with increased independent risk factors of cardiovascular disease. We investigated the difference between the degree of obesity, metabolic syndrome risk factors, plasma homocysteine and anthropometric obesity factors. Totally 398 participated in a medical check-up program were selected for this study. Subjects were categorized into three groups according to the number of metabolic syndrome components present as defined by the NCEP-ATP III criteria; Absent (0 criteria, n=124), Pre-MetS (1-2 criteria, n=220) and MetS (${\geq}3$ criteria, n=54). Body mass index (BMI) is a measure used to distinguish between normal weight, overweight and obesity. MetS presented higher homocysteine than Absent (p<.05) and obesity higher than normal weight (p<.01). When Absent+Pre-MetS was used to classify obese or not, obesty presented higher homocysteine than non-obese (p<.05). Further homocysteine levels positively correlated with weight, BMI, waist circumference, hip circumference and waist-hip ratio (WHR). Especially WHR is not only MetS (r=0.378, p<.001) but also Absent+Pre-MetS (r=0.305, p=0.029) significantly positively correlated with homocysteine. The results of our study indicate that homocysteine is related closely to obesity. Although obesity has not been diagnosed with metabolic syndrome, obesity related with increased homocysteine.