• Journal of the Korean Society of Radiology
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• v.14 no.7
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• pp.965-973
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• 2020

The purpose of this study was to quantitatively correlate the change of flow velocity and signal voiding in TOF-MRA. We made our phantom to control the flow velocity, and changed the flow velocity in 16 steps from 8.0 to 127.3 mc/s. The TOF-MRA test was performed using a 3.0T MRI system and the signal intensity was measured by classifying the signal voiding length and image into the In flow, Mid flow, and Out flow. The length of signal voiding was the longest when the flow velocity was 127.3 cm/s and the signal intensity decreased with increasing flow velocity(p<0.05). In flow(-.547) and Mid flow(-.643) were negatively correlated with flow velocitys(p<0.05). In conclusion, it was confirmed that the increase in flow velocity was a major factor causing signal voiding in TOF-MRA. In the future, this study will provide basic data when studying sequences and parameters to reduce signal voiding in models with a high flow velocity.

• Molecules and Cells
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• v.38 no.3
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• pp.195-201
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• 2015

Antibodies are powerful defense tools against pathogens but may cause autoimmune diseases when erroneously directed toward self-antigens. Thus, antibody producing cells are carefully selected, refined, and expanded in a highly regulated microenvironment (germinal center) in the peripheral lymphoid organs. A subset of T cells termed T follicular helper cells (Tfh) play a central role in instructing B cells to form a repertoire of antibody producing cells that provide life-long supply of high affinity, pathogenspecific antibodies. Therefore, understanding how Tfh cells arise and how they facilitate B cell selection and differentiation during germinal center reaction is critical to improve vaccines and better treat autoimmune diseases. In this review, I will summarise recent findings on molecular and cellular mechanisms underlying Tfh generation and function with an emphasis on T cell costimulation.

• Journal of Korea Multimedia Society
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• v.19 no.2
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• pp.360-374
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• 2016

Since WSNs (Wireless Sensor Networks) applied to their application areas such as smart home, smart factory, environment monitoring, etc., depend on sensor data, the sensor data is the most important among WSN components. The resources of each node consisting of WSN are extremely limited in energy, hardware and so on. Due to these limitation, communication failure probabilities become much higher and the communication failure causes data loss to occur. For this reason, this paper proposes 2MC (Maximum/Minimum Compression) that is a method to compress sensor data by selecting circular queue-based maximum/minimum sensor data values. Our proposed method reduces sensor data losses and value errors when they are recovered. Experimental results of 2MC method show the maximum/minimum 35% reduction efficiency in average sensor data accumulation error rate after the 3 times compression, comparing with CQP (Circular Queue Compression based on Period) after the compressed data recovering.

• Animal Systematics, Evolution and Diversity
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• v.12 no.1
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• pp.67-77
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• 1996

Some hydromedusae were collected from the western and southern coasts of Korean Peninsula during May to October, 1995. They were identified into Turritopsis nutricula(McCrady, 1856); Cladonema radiatum Dujardin, 1843; Eirene menoni Kramp, 1953 and Gonionemus vertens A. Agassiz, 1862. Of which the hydromedusa of T. nutricula is preliminary known in Korean waters, and the remainders are new to the Korean fauna.

• Proceedings of the Korean Society of Embryo Transfer Conference
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• 1997.05a
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• pp.9-15
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• 1997

치밀 난구세포로 둘러싸인 소 난자를 $38^{circ}C$. 5% $CO_2$ 배양기에시 5% superovulated cow serum(SCS)이 첨가된 m-TCM 199 medium 으로 $20{\sim}22$ 시간 배양하였으며, 수정능이 획득된 정자와 체외수정하였다. 7일${\sim}$8일경의 수정란을 1.3M methyl cellosolve(MC), 1.1M diethylene glycol(DEG), 1.8M ethylene glycol(EG), 1.6M propylene glycol(PG) 및 1.1M 1,3-butylene glycol(BG) 용액에서 10분간 평형시킨 후 0.25 ml 스트로내에 장전하였다. 스트로를 $0^{\circ}C$의 alcohol bath freezer에 넣고 $-6^{\circ}C$까지 $-1^{\circ}C$/분 속도로 냉각, 식빙 후 10분간 정체시켰으며, $-0.3^{\circ}C$/분 또는 $-0.5^{\circ}C$/분으로 $-30^{\circ}C$까지 냉각 후 스트로를 액체질소에 침지하여 보관하였다. 수정란이 들어있는 스트로를 $30^{\circ}C$ 온수에서 융해하였으며, 수정란을 TCM 199 medium 으로 옮긴 후 5% SCS가 첨가된 TCM 199 medium 에서 48시간 배양하였다. 수정란이 양호한 형태를 유지하며 나중의 발육단계로 진행된 것을 생존한 것으로 간주하였다. 각 종류의 동해방지제에서 동결된 수정란의 일부는 융해 후 동해방지제를 제거하지 않고 직접 비외과적으로 이식하였다. 동결-융해 후 동해방지제의 종류에 따른 탈출배반포 발달율은 EG 50.0%, MC 53.6%, DEG 56.9%, PG 58.0% 그리고 BG 11.5%였다. $-0.3^{\circ}C$/분 또는 $-0.5^{\circ}C$/분 으로 냉각한 수정란의 생존율은 두 그룹간에 유의적인 차이가 없었으나 (P<0.05), 탈출배반포 발달율은 -0.5분 $^{\circ}C$/분(22.6%, 12/53)보다 $-0.3^{\circ}C$/분(64.6%, 31/48) 냉각시에 유의적으로 높았다(P<0.01). 동해방지제의 종류에 따른 수정란의 수태율은 MC 48%(10/21). DEG 30%(3/10), EG 74%(20/27) 및 PG 40%(4/10) 였다. 이러한 결과로 보아 MC, DEG, EG 그리고 PG는 소의 체외수정란의 동결을 위한 동해방지제로서 이용될 수 있음을 보여주었다.

• Journal of Korean Academy of Nursing
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• v.22 no.4
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• pp.476-490
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• 1992

This study was designed to develop and test a structural model for maternal adaptation and family stress in families with mentally handicapped children. A hypothetical model was constructed on the basis of the family stress theory developed by McCubbin etc. The model included 6 theoretical concepts and 11 paths. For the purpose of the model testing, empirical data were collected from May to August, 1992. The subjects of the study constituted 190 mothers of children in five special schools and one private institute in Seoul and Choong Nam. An SPSS PC＋ and PC－LISREL 7.13 computer programs were used for descriptive and covariance structure analysis. The results of the study were as follows. (1) The hypothetical model showed itself a good fit to the empirical data ［Chi - square＝18.35(df＝7, P＝0.005), Goodness of Fit Index＝0.991, Adjusted Goodness of Fit Index＝0.959, Root Mean Square Residual＝0.042), Non Normed Fit Index＝0.90, Normed Fit Index＝0.96］. (2) The results of Hypothesis testing indicated : 1) Social support(${\gamma}$$_{11}$＝.238, T＝2.352), Family functioning(${\gamma}$$_{12}$＝.729, T＝5.957) and Family life event stress(${\gamma}$$_{13}$＝.125) had direct effects on situational definition. 2) Life event stress(${\gamma}$$_{23}$＝.319, T＝3.872) had direct effects on the effect of the handicapped child on the family. Family functioning(${\gamma}$$_{22}$＝-.245) and situational definition($\beta$$_{21}$＝-.335, T＝3.227) had direct effects on the effect of the handicapped child on the family. 3) Situational definition($\beta$$_{31}$＝-.273, T＝3.493), family life event stress (${\gamma}$$_{33}$＝.124, T＝2.169) and the effect of the handicapped child on the family($\beta$$_{32}$＝.264, T＝-3.227) showed the direct effect on the maternal adaptation. The model was supported by the empirical data. Thus it was suggested that the model could be applied to family nursing care with the families with the mentally handicapped. The construction and testing of the comprehensive model seem to be the first trial in Korea.a.a.a.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.12
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• pp.502-509
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• 2020

The aim of this study was to compare the effects of a horseback riding simulator, McKenzie, and gym ball exercises on the Korean-Oswestry Disability Index (K-ODI) and muscle activation in people suffering from chronic low back pain. The study was conducted on 30 adults with a K-ODI of 5 or more and chronic low back pain. This experiment was conducted from May to June 2020. They were randomly divided into the horse-riding exercise group (HEG), McKenzie exercise group (MEG), and the gym ball exercise group (GEG). Each group performed the relevant exercises for six weeks, three times a week. The low back pain was measured with K-ODI, and muscle activation was measured with surface electromyography (SEMG). A paired t-test was conducted to verify the change before and after the experiment in the groups, and a one-way ANOVA was conducted to verify the difference between the three groups. The results of the study showed significant differences before and after the experiment. K-ODI and muscle activity improved (p>.05), and significant differences were also found between the groups (p<.05). This study concluded that horse riding and McKenzie exercises could be effective methods for the treatment of pain and to stabilize the lumbar region in patients with chronic low back pain.

• Communications for Statistical Applications and Methods
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• v.29 no.3
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• pp.373-391
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• 2022

The distribution of observations in most econometric studies with spatial heterogeneity is skewed. Usually, a single transformation of the data is used to approximate normality and to model the transformed data with a normal assumption. This assumption is however not always appropriate due to the fact that panel data often exhibit non-normal characteristics. In this work, the normality assumption is relaxed in spatial mixed models, allowing for spatial heterogeneity. An inference procedure based on Bayesian mixed modeling is carried out with a multivariate skew-elliptical distribution, which includes the skew-t, skew-normal, student-t, and normal distributions as special cases. The methodology is illustrated through a simulation study and according to the empirical literature, we fit our models to non-life insurance consumption observed between 1998 and 2002 across a spatial panel of 103 Italian provinces in order to determine its determinants. Analyzing the posterior distribution of some parameters and comparing various model comparison criteria indicate the proposed model to be superior to conventional ones.

• Journal of the Korean Solar Energy Society
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• v.26 no.3
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• pp.71-78
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• 2006

Thermodynamic irreversibility analysis of an air-to-water heat pump system is analyzed in this study. This analysis shows the distribution of irreversibilities(true losses in thermodynamic sense) through the system components and informs us of a potential improvements with the irreversibility factor decreases. The results show that the largest irreversibilities occur in the motor-compressor unit. The remaining irreversibilities are distributed relatively uniformly through the other parts including utilization system. The increase of performance can be attained through either the improvement of adiabatic efficiency of motor-compressor unit(${\eta}_{mc}$) or the reduction of temperature difference(${\Delta}T$). With the decrease of utilization temperature($T_u$) COPH also increases but the exergetic efficiency decreases. The increase of COPH of about 0.05 can be accomplished with 1K decrease of ${\Delta}T$ or $T_u$.

• Journal of Korean Ophthalmic Optics Society
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• v.13 no.3
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• pp.19-28
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• 2008

Purpose: To understand symptoms and signs in soft contact lens wearers the authors evaluate the attribution of the tear test to the contact lens related symptoms and signs. Methods: Sixty-two healthy soft contact lens wearers (23.95${\pm}$4.38 years old, 18.60${\pm}$16.92 months of prior lens wear) were participated in this study. 3 kinds of tear test and McMonnies' questionnaire test were performed for the soft contact lens wearers and subjective symptoms and objective signs were graded using CCLRU scales during the study period. Results: In this surveys, we found ocular dryness, redness and tiredness are the most common frequent and severe symptoms in soft contact lens wearers. Frequency of the ocular dryness, redness and tiredness are associated with grittiness, burning sensation and foreign body sensation respectively, and severity of the photophobia, foreign body sensation are associated with unstable vision and grittiness and which are associated with score of McMonnies' Questionnaire. Conjunctival redness and limbal redness are major signs but those are not need to be clinical care and rarely occurred corneal and conjunctival staining which are associated with tear break-up-time statistically. Conclusions: Dryness, redness and tiredness are primary common symptoms in Korean soft contact lens wearers. The frequency of those symptoms are increased with the period of soft contact lens wear and those are associated with other symptoms but have no relationship with signs.