• 대한한방부인과학회지
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• 제30권4호
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• pp.45-58
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• 2017

Objectives: The aim of this trial is to investigate the effect of Ginseng and Wild Cultivated Ginseng to Heat pattern subject. Methods: Eighty-nine Subjects were diagnosed as heat pattern by Cold-Heat Patternization and divided into Ginseng group (n=30), Wild Cultivated Ginseng group (n=31) and Placebo group (n=28) in their 1 st visit. In each visit, The researchers measured the subject's facial temperature using the infrared thermometer (Testo 835-T1). After that, The subjects were asked to mark the current score of flushing on the Visual Analogue Scale (VAS) and to complete the Chalder-Fatigue Scale (CFS) in each visit. The subjects took the test drug for one week and returned the remaining drug on the 2nd visit. The trial result was analyzed with one-way ANOVA using SPSS for Windows version 18. Results: 1. Systolic blood pressure was significantly lower in the Ginseng group and Wild Cultivated Ginseng group than in the control group (p=0.021). 2. There was no significant difference in facial temperature between each groups. 3. The current score of flushing showed the greatest decrease in the Ginseng group compared to the other groups but there was no significant difference (p=0.205). 4. The score of Chalder-Fatigue Scale was decreased in all groups but not statistically significant (p=0.180). Conclusions: This study showed that taking Ginseng extract and Wild Cultivated Ginseng extract do not affect to heat-rising reaction to the subjects diagnosed as heat pattern.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제19권1호
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• pp.12-19
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• 2016

Purpose: This study was performed to evaluate the quality of sleep in snoring obese children without obstructive sleep apnea (OSA); and to study the possible relationship between sleep interruption and gastroesophageal reflux (GER) in snoring obese children. Methods: Study subjects included 13 snoring obese children who were referred to our sleep lab for possible sleep-disordered breathing. Patients underwent multichannel intraluminal impedance and esophageal pH monitoring with simultaneous polysomnography. Exclusion criteria included history of fundoplication, cystic fibrosis, and infants under the age of 2 years. Significant association between arousals and awakenings with previous reflux were defined by symptom-association probability using 2-minute intervals. Results: Sleep efficiency ranged from 67-97% (median 81%). A total of 111 reflux episodes (90% acidic) were detected during sleep, but there were more episodes per hour during awake periods after sleep onset than during sleep (median 2.3 vs. 0.6, p=0.04). There were 279 total awakenings during the sleep study; 56 (20.1%) of them in 9 patients (69.2%) were preceded by reflux episodes (55 acid, 1 non-acid). In 5 patients (38.5%), awakenings were significantly associated with reflux. Conclusion: The data suggest that acid GER causes sleep interruptions in obese children who have symptoms of snoring or restless sleep and without evidence of OSA.

• Journal of Korean Neurosurgical Society
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• 제59권1호
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• pp.26-36
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• 2016

Objective : This study investigated whether pyrosequencing can be used to determine the methylation status of the MGMT promoter as a clinical biomarker using relatively old archival tissue samples of glioblastoma. We also examined other prognostic factors for survival of glioblastoma patients. Methods : The available study set included formalin-fixed paraffin-embedded (FFPE) tissue from 104 patients at two institutes from 1997 to 2012, all of which were diagnosed histopathologically as glioblastoma. Clinicopathologic data were collected by review of medical records. For pyrosequencing analysis, the PyroMark Q96 CpG MGMT kit (Qiagen, Hilden, Germany) was used to detect the level of methylation at exon 1 positions 17-39 of the MGMT gene, which contains 5 CpGs. Results : Methylation of the MGMT promoter was detected in 43 (41.3%) of 104 samples. The average percentage methylation was $14.0{\pm}16.8%$ overall and $39.0{\pm}14.7%$ for methylated cases. There was no significant pattern of linear increase or decrease according to the age of the FFPE block (p=0.687). In multivariate analysis, age, performance status, extent of surgery, method of adjuvant therapy, and methylation status estimated by pyrosequencing were independently associated with overall survival. Additionally, patients with a high level of methylation survived longer than those with low methylation (p=0.016). Conclusion : In this study, the status and extent of methylation of the MGMT promoter analyzed by pyrosequencing were associated with overall survival in glioblastoma patients. Pyrosequencing is a quantitative method that overcomes the problems of MSP and a simple technique for accurate analysis of DNA sequences.

• Design & Manufacturing
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• 제13권3호
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• pp.35-40
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• 2019

As the consumer market in the cosmetic, vehicle manufacturing and aerospace industries grows, the demand for manufacturing industries using on injection mold technology. Also, such manufacturing technology of metal machining is expensive, and the shape is limited. Cosmetic cushion fact products are divided into outer relevant to the exterior of the product and inner containers containing the actual contents. In the case of the inner container, it needs to be combined with the upper and lower cases. As environmental regulations are strengthened internationally, the use of a large number of component parts can result in significant losses in recycling and economics. Therefore, this study aims to perform injection molding analysis through injection molding simulation to develop a cushion fact container that can be recycled through the unification of products and materials using polypropylene to cope with environmental regulations. In the case of injection molding conditions, Injection Time(sec): 4.5, Cooling Time(sec): 13, Resin Temperature($^{\circ}C$): 240, and Pressure(MPa): 30 were determined. The results of injection molding simulation according to the two design methods were compared with the sync mark which shows the problem of filling and injection molding.

• 한국컴퓨터정보학회논문지
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• 제23권1호
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• pp.75-84
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• 2018

In this study, the researchers attempted to automate the process of painting the characters on the road surface, which is currently done by manual labor, by using the information and communication technology. Here are the descriptions of how we put in our efforts to achieve such a goal. First, we familiarized ourselves with the current regulations about painting letters or characters on the road, with reference to Road Mark Installation Management Manual of the National Police Agency. Regarding the graphemes, we adopted a new one using connection components, in Gothic print characters which was within the range of acceptance according to the aforementioned manual. We also made it possible for the automated program to recognize the graphemes by means of the feature dots of the isolated dots, end dots, 2-line gathering dots, and gathering dots of 3 lines or more. Regarding the database, we built graphemes database for plotting information, classified the characters by means of the arrangement information of the graphemes and the layers that the graphemes form within the characters, and last but not least, made the character shape information database for character plotting by using such data. We measured the layers and the arrangement information of the graphemes consisting the characters by using the information of: 1) the information of the position of the center of gravity, and 2) the information of the graphemes that was acquired through vertical exploration from the center of gravity in each grapheme. We identified and compared the group to which each character of the database belonged, and recognized the characters through the use of the information gathered using this method. We analyzed the input characters using the aforementioned analysis method and database, and then converted into plotting information. It was shown that the plotting was performed after the correction.

• 한국컴퓨터정보학회논문지
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• 제26권7호
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• pp.19-27
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• 2021

본 논문에서는 영상 속 인물을 탐지하고 얼굴 영역을 검출하는 방법을 제안하며, 이 방법은 2가지 작업으로 구성한다. 첫째, 서로 다른 두 명의 인물을 구분하여 프레임 내 인물의 얼굴 위치를 탐지한다. 빠른 탐지를 위해 영상 내 물체를 실시간으로 검출하는 YOLO(You Only Look Once)를 이용하여 얼굴의 위치를 탐지하고 객체탐지상자로 나타낸다. 둘째, 객체탐지상자를 바탕으로 정확한 얼굴 면적을 검출하기 위해 3가지 영상처리 방법을 제시한다. 각 방법은 검출 도형으로 추정한 영역에서 추출한 HSV 값을 이용하여 인물의 얼굴 영역을 검출하였으며 검출 도형의 크기와 모양을 바꾸어 각 방법의 정확도를 비교하였다. 각 얼굴 검출 방법은 신뢰성 검증을 위해 비교 데이터와 영상처리 데이터로 비교 및 분석하였다. 그 결과 원형, 직사각형, 분할 직사각형 방법 중 분할된 직사각형 방법을 사용했을 때 87%로 가장 높은 정확도를 달성하였다.

• 대한한의학원전학회지
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• 제32권1호
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• pp.29-48
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• 2019

Objectives : The purpose of this study is to investigate which system the FanQie notation of "Taisu(太素)" followed by comparing FanQie notation appearing in "Taisu", with the Sound button(聲紐) and Rhyme system(韻類) of the FanQie notation appearing in the "Qieyun(切韻)" system phonology book and "Guangyun(廣韻)". Methods : Followed by organizing the FanQie list in "Taisu", in comparing this list with the top and bottom characters of FanQie in the "Qieyun" system phonology book and "Guangyun", this study explores the similarity of the system after noting the Sound button and the Rhyme system. Results & Conclusions : 1. Compared to FanQie of "Taisu" with that of "Qieyun" system, the Sound button and Rhyme system were 61.54% identical, and when comparing FanQie of "Taisu" with that of "Guangyun", the Sound button and Rhyme system were 55.45% identical. 2. Comparing FanQie top and bottom letters themselves of the "Taisu" and "Qieyun" system, of the 217 FanQie sound notation Chinese characters, FanQie top and bottom letters of 18 characters were the same, accounting for 8.29%, and when compared to the "Taisu" with the FanQie top and bottom characters of "Guangyun", 15 FanQie top and bottom characters were the same, accounting for 6.91%. 3. Of the total 11,500 characters in "Qieyun", the ratio of FanQie notation Chinese characters in "Taisu" was 1.89%, and among them, nine characters came out in "Taisu" FanQie notation while there was none in "Qieyun". This accounted for 4.15% of 217 FanQie notation sound Chinese characters in "Taisu", demonstrating that this represented a relatively high ratio. 4. Conclusionally "Taisu" was more closely related to "Qieyun" system phonology book than "Guangyun" in FanQie notation, and there is also a possibility that Yang Shangshan has created some FanQie notation by himself or additionally referred to other phonology books that are not "Qieyun" system phonology book.

• 천문학회보
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• 제44권1호
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• pp.42.2-42.2
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• 2019

Turbulence is one of the natural phenomena in molecular clouds. It affects gas density and velocity fluctuation within the molecular clouds and controls the mode and tempo of star formation. However, despite many years of study, the properties of turbulence remain poorly understood. As part of the Taeduk Radio Astronomy Observatory (TRAO) Key Science Program (KSP), "mapping Turbulent properties In star-forming MolEcular clouds down to the Sonic scale (TIMES; PI: Jeong-Eun Lee)", we have fully mapped two star-forming molecular clouds, the Orion A and the Ophiuchus molecular clouds, in 3 sets of lines ($^{13}CO$ J=1-0, $C^{18}O$ J=1-0, HCN J=1-0, $HCO^+$ J=1-0, CS J=2-1, and $N_2H^+$ J=1-0) using the TRAO 14-m telescope. We apply a statistical analysis, Principal Component Analysis (PCA), which can recover an underlying turbulent-power spectrum from an observed P-P-V spectral map. We compare turbulence properties not only between the two clouds, but also between different parts within each cloud. We present the first result of our observation program.

• The Korean Journal of Pain
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• 제34권1호
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• pp.72-81
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• 2021

Background: In the literature, there have been debates as to whether smartphone use has negative effects on physical and mental health. The present study investigated the extent to which smartphone addiction impacts on musculoskeletal pain prevalence among university students. Methods: The questionnaire consisted of three sections: demographic information, the Smartphone Addiction Scale (SAS), and the modified Nordic Musculoskeletal Questionnaire. Results: A total of 249 participants were included in this cross-sectional study. The body parts that were reported with highest prevalence of musculoskeletal pain were the upper back (70.3%), neck (65.9%), and wrists/hands (68.7%). The SAS scores were correlated with duration of smartphone use on a typical day (P = 0.001), duration of owning a smartphone (P = 0.027), and musculoskeletal pain prevalence in the neck (P = 0.001), wrists/hands (P = 0.001), shoulders (P = 0.025), and upper back (P = 0.023). The SAS score was significantly associated with prevalence of musculoskeletal pain in the neck (odd ratio [OR], 1.08; 95% confidence interval [CI], 0.98-1.10; P = 0.002), wrists/hands (OR, 1.07; 95% CI, 0.97-1.09; P = 0.001), and upper back (OR, 1.10; 95% CI, 0.98-1.11; P = 0.033). Conclusions: The findings indicated that the upper back, neck, and wrists/hands have a higher prevalence of musculoskeletal pain among smartphone users, particularly those with a smartphone addiction. Smartphone addiction scores were correlated with duration of smartphone use on a typical day, duration of owning smartphone, and musculoskeletal pain prevalence in the neck, wrists/hands, shoulders, and upper back.

• 한국콘텐츠학회논문지
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• 제21권3호
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• pp.645-652
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• 2021

이 논문에서는 상품의 포장디자인이 단순히 도안에 불과한 것이 아닌 상표로서의 식별력을 가질 수 있음을 인정하여 화제가 되었던 일명 '허니버터아몬드 판결'을 분석하였다. 위 판결에서는 다툼의 대상이 된 등록상표의 식별력 여부와 선사용상표와의 유사성 여부가 쟁점이 되었다. 우선 다툼의 대상이 된 등록상표의 식별력과 관련하여, 법원은 포장 전면 도형 부분의 표현 방법과 전체적인 구도 등의 특수성이 흔히 사용되는 표현 방식과 구분되는 이상 해당 도안은 출처의 식별표지로서 기능할 수 있다고 하였고 특히 과자 등 저관여 제품에서는 포장 전면 도형을 통해 출처를 식별하는 것이 일반적이라는 점도 이를 뒷받침한다는 등의 이유로 해당 등록상표의 식별력을 인정하였다. 한편 선사용상표(과자 '허니버터칩')와는 그 호칭 및 관념상 차이가 있어 그 지배적 인상이 유사하다고 보기 어렵다고 하였다. 위 판결은 상품의 포장디자인도 그 구도와 표현 방식의 독특성을 통해 상표로서의 식별력을 획득할 수 있다고 보아 포장 도안의 상품 표지로서의 기능을 인정한 데 의의가 있다. 다만 독점부당성을 부인하면서도 그에 대한 구체적 설명은 다소 부족하다는 점은 아쉬운 부분이다.