• 제목/요약/키워드: MA Control

검색결과 902건 처리시간 0.026초

"동의보감(東醫寶鑑)"과 "동의수세보원사상초본권(東醫壽世保元四象草本卷)"에 나타난 양생관(養生觀)에 대한 고찰 (A study of preservation of health in the ${\ulcorner}$Dongyi Bogam${\lrcorner}$ and ${\ulcorner}$Dongyi Soose Bowon Sasang Chobongyun${\lrcorner}$)

  • 이수경;이의주;고병희;송일병;정용재
    • 사상체질의학회지
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    • 제14권2호
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    • pp.25-34
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    • 2002
  • To understand characteristic of preservation of health in Sasang constitutional medicine, 1 first study preservation of health In ${\ulcorner}$Dongyi Bogam${\lrcorner}$, and then study preservation of health in the ${\ulcorner}$Dongyi Soose Bowon Sasang Chobongyun${\lrcorner}$ particularly Inherent vitality(命脈實數) and Regimen in ordinary life(生息充補之道) which shows early thought of Lee Je-ma. I acquire relation and difference between ${\ulcorner}$Dongyi Bogam${\lrcorner}$ and Dongyi Soose Bowon Sasang Chobongyun${\lrcorner}$, and conclude as follows. 1. In preservation of health ${\ulcorner}$Dongyi Bogam${\lrcorner}$ says Ups and downs of Qi according to degree, tells congenital health and acquired care of health, grades Jin-In, Ji-In, Seong-In, Hyeon-In according to degree of moral culture, and especially emphasizes managing mind which is based on Taoism. 2. In ${\ulcorner}$Dongyi Soose Bowon Sasang Chobongyun${\lrcorner}$ Dongmu divides human being to Sasangin(Taeyangin, Taeumin, Soyangin, Soeumin) according to Large & small of viscera, and regards as determine lift span and rendition of disease & health according to Inherent vitality which is degree of Small viscera. 3. Inherent vitality of Sasangin is supplemented by Regimen in ordinary life. Because Regimen in ordinary life decreases according to age, Dongmu emphasizes managing mind through an autonomic Knowledge Deed to maintain Regimen in ordinary life. 4. In the way of managing mind ${\ulcorner}$Dongyi Bogam${\lrcorner}$ says Taoist moral culture, but Dongmu emphasized control of knowledge and Deed by Confucian moral culture and the mind of control others through confucian self-control.

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‘쓰가루’사과의 유통용 신선도유지 MA 포장 효과 (Modified Atmosphere Packaging of ‘Tsugaru’Apple(Malus domestica Borkh) for Distribution)

  • 박종대;홍석인;박형우;김동만
    • 한국식품저장유통학회지
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    • 제6권4호
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    • pp.357-364
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    • 1999
  • 수확후 품질이 급속히 저하되어 저장력이 약한 단점 때문에 유통기간이 매우 짧은 '쓰가루' 사과를 대상으로 플라스틱 필름과 에틸렌 흡착제 첨가에 따른 MAP(modified atmosphere packaging)의 품질유지 효과를 비교하였다. 필름 포장내의 $O_2$$CO_2$ 함량은 포장 후 4~6일 후 까지 급격히 변화하였고, 에틸렌 농도도 밀봉 직후 급격히 증가하여 저장 4일 후 40 $\mu\textrm{m}$ 두께의 LDPE 필름 포장구(40LD)에서 2,045 ppm까지 증가한 후 감소하였다. 저장중 품질변화 측정에서 대조구의 중량손실은 저장 60일 후 3.0% 이상이었으나 포장구는 저장 60일 후에도 0.6% 이하의 수준이었다. 저장중 적정산도 및 가용성고형분 함량 변화는 처리구간 유의적인 차이가 없었으나, pH는 대조구와 포장구간에 차이가 있었다 '쓰가루'의 저장중 경도는 저장초기 18일까지 급속히 감소하였으며, 40LD와 40$\mu\textrm{m}$ 두께의 에틸렌 흡착제 첨가 포장구(40LP)는 저장 60일 후 경도가 높게 유지되었다. 저장중 과피색 변화는 색소 분해로 인한 퇴색이 빠르게 진행되었으며, 저장 30일 이후부터 40LP가 저장중 변색이 가장 억제되었다. 외관품질은 저장 30일 후부터 대조구와 포장구가 차이가 났다. 관능검사에서도 대조구에 비해 포장구가 외관과 종합적기호도에서 유의적으로 우수함을 보였다. 이와 같은 결과를 종합해 볼 때 조생종 사과인 '쓰가루'의 유통중 신선도 유지를 위한 포장재료로 40 $\mu\textrm{m}$ 두께의 LDPE 필름의 사용가능성이 있으며 에틸렌 흡착제를 필름안에 같이 처리하면 더욱 효과가 있을 것으로 판단되었다.

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Intravenous patient-controlled analgesia hydromorphone combined with pregabalin for the treatment of postherpetic neuralgia: a multicenter, randomized controlled study

  • Huang, Ying;Xu, Chenjie;Zeng, Tao;Li, Zhongming;Xia, Yanzhi;Tao, Gaojian;Zhu, Tong;Lu, Lijuan;Li, Jing;Huang, Taiyuan;Huai, Hongbo;Ning, Benxiang;Ma, Chao;Wang, Xinxing;Chang, Yuhua;Mao, Peng;Lin, Jian
    • The Korean Journal of Pain
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    • 제34권2호
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    • pp.210-216
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    • 2021
  • Background: Postherpetic neuralgia (PHN) is the most common complication of acute herpes zoster. The treatment of PHN remains a challenge for clinical pain management. Despite the effectiveness of anticonvulsants, antidepressants, and lidocaine patches in reducing PHN, many patients still face intractable pain disorders. In this randomized controlled study, we evaluated whether hydromorphone through intravenous patient-controlled analgesia (IV PCA) was effective in relieving PHN. Methods: Patients with PHN were randomly divided into two groups, one group received oral pregabalin with IV normal saline, another group received oral pregabalin with additional IV PCA hydromorphone for two weeks. Efficacy was evaluated at 1, 4, and 12 weeks after the end of the treatments. Results: Two hundred and one patients were followed up for 12 weeks. After treatment, numerical rating scale (NRS) score of patients in the hydromorphone group was significantly lower than that of the control group, and the difference of NRS scores between the two groups was statistically significant at 4 and 12 weeks after treatment. The frequency of breakthrough pain in the hydromorphone group was significantly lower than that in the control group 1 and 4 weeks after treatment. After treatment, the quality of sleep in the hydromorphone group was significantly improved compared with the control group. The most common adverse reactions in the hydromorphone group were dizziness and nausea, with no significant respiratory depression. Conclusions: IV PCA hydromorphone combined with oral pregabalin provides superior pain relief in patients with PHN, which is worthy of clinical application and promotion.

홍삼·백년초 복합물이 관절염 개선에 미치는 효과 (Effects of red ginseng and Baeknyeoncho complex on the arthritis improvement)

  • 이승현;이창현;김홍준;김영식;신민지;김지현;마상용;이세연;권진;오찬호
    • 대한한의학방제학회지
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    • 제29권2호
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    • pp.81-91
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    • 2021
  • Objectives : This study was conducted to evaluate the efficacy of a complex mixture of natural substances of ginseng and baeknyeoncho on the arthritic rats. Methods : In vitro experiments were conducted to ensure the stability of the complex. After setting toxicity and concentration by MTT assay, the antioxidant effect was measured through DPPH and ABTS radical scavenging activity. To confirm the anti-inflammatory effects of the complex, levels of nitric oxide (NO) and pro-inflammatory cytokines (IL-1β, TNF-α) were measured in LPS-treated macrophage cell lines (RAW264.7). We injected monosodium iodoacetate (MIA) 50 μl (60 mg/ml) into knee joints of rats to induce osteoarthritis. The rats were divided into three groups (normal (n=5), control (n=5), and OR (n=5) group). The control group consumed 2 mg/kg of physiological saline once a day for 4 weeks, and the OR group was mixed at a concentration of 416.5 mg/kg of Baengnyeoncho (O) and 208.25 mg/kg of red ginseng (R) and ingested 1 mL each 5 days a week. Results : This complex increased the DPPH and ABTS radical scavenging rate. The complex decreased NO production and pro-inflammatory cytokine production of macrophages. In the OR group, the secretion of cytokine in serum was decreased. In histopathological examination, the joint tissue of the composite showed less damage to the synovial membrane, cartilage, and fibrous tissue than the control group. Conclusions : As a result of this study, natural complexes have antioxidant, anti-inflammatory and cartilage protection effects. Therefore, we expect the complex to be effective in treating osteoarthritis.

Epidemiological investigation of porcine pseudorabies virus and its coinfection rate in Shandong Province in China from 2015 to 2018

  • Ma, Zicheng;Han, Zifeng;Liu, Zhaohu;Meng, Fanliang;Wang, Hongyu;Cao, Longlong;Li, Yan;Jiao, Qiulin;Liu, Sidang;Liu, Mengda
    • Journal of Veterinary Science
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    • 제21권3호
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    • pp.36.1-36.9
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    • 2020
  • Background: Pseudorabies, also known as Aujeszky's disease, is caused by the pseudorabies virus (PRV) and has been recognized as a critical disease affecting the pig industry and a wide range of animals around the world, resulting in great economic losses each year. Shandong province, one of the most vital food animal-breeding regions in China, has a very dense pig population, within which pseudorabies infections were detected in recent years. The data, however, on PRV epidemiology and coinfection rates of PRV with other major swine diseases is sparse. Objectives: This study aimed to investigate the PRV epidemiology in Shandong and analyze the current control measures. Methods: In this study, a total number of 16,457 serum samples and 1,638 tissue samples, which were collected from 362 intensive pig farms (≥ 300 sows/farm) covered all cities in Shandong, were tested by performing enzyme-linked immunosorbent assay (ELISA) and polymerase chain reaction (PCR). Results: Overall, 52.7% and 91.5% of the serum samples were positive for PRV-gE and -gB, respectively, based on ELISA results. In addition, 15.7% of the tissue samples were PCR positive for PRV. The coinfection rates of PRV with porcine circovirus type 2 (PCV2), porcine reproductive and respiratory syndrome virus, and classical swine fever virus were measured; coinfection with PCV2 was 35.0%, higher than those of the other two viruses. Macroscopic and microscopic lesions were observed in various tissues during histopathological examination. Conclusions: The results demonstrate the PRV prevalence and its coinfection rates in Shandong province and indicate that pseudorabies is endemic in pig farms in this region. This study provides epidemiological data that can be useful in the prevention and control of pseudorabies in Shandong, China.

건조(乾燥)표고버섯의 각종(各種) 용매추출물(溶媒抽出物)의 항산화작용(抗酸化作用)의 효과(效果) (Effects of the Substances Extracted from Dried Mushroom(Lentinus edodes) by Several Organic Solvents on the Stability of Fat)

  • 마상조
    • 한국식품과학회지
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    • 제15권2호
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    • pp.150-154
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    • 1983
  • 몇가지 대표적인 유기용매를 사용하여 열풍건조(풍속 : 2.0m/sec, $50^{\circ}C$)한 표고버섯으로부터 추출한 성분의 식용대두유에 대한 항산화효과를 POV와 TBA-가(價)의 변화로 측정하여 이들 버섯에서의 추출물들의 대두유에 대한 산패억제효과를 보고자 하였다. 그 결과는 아래와 같다. 1. 건조온도 $50^{\circ}C$, 건조공기의 속도 2.0m/sec로 일정하게 유지(維持)된 열풍건조기안에서 20시간 건조 후의 표고버섯의 수분함량은 15.12%(wet basis)였었다. 2. Control 및 각 시료구의 시료의 POV는 저장일수가 14일 후에 각각 $1.36{\pm}0.37,\;1.02{\pm}0.06,\;1.07{\pm}0.06,\;1.27{\pm}0.22$$1.43{\pm}0.01$로서 서로 비슷하였으나 저장일수 56일 경과 후에는 각각 $98.49{\pm}9.49,\;6.38{\pm}0.36,\;3.92{\pm}0.03,\;29.19{\pm}3.58$$65.62{\pm}3.36$으로서 control와 기타 시료구 시료의 POV 사이에는 큰 차이가 있었다. 특히 sample4, control보다 유지의 산패억제효과가 컸음은 주목할만 하다. 3. Control 및 각 시료구 시료의 TBA-가(價)의 변화는 POV와 비슷한 경향을 보여 주었다. 즉 저장일수 14일 경과후의 TBA-가(價)는 $0.153{\pm}0.03,\;0.112{\pm}0.01,\;0.180{\pm}0.05,\;0.165{\pm}0.91$$0.201{\pm}0.01$로서 큰 차이가 없었으나 56일 경과후에는 각각 $0.678{\pm}0.13,\;0.303{\pm}0.06,\;0.410{\pm}0.03,\;0.341{\pm}0.03$$0.302{\pm}0.05$로서 Control와 기타 시료구 시료의 TBA-가(價) 사이에 큰 차이를 보였었다. 한편, POV의 경우와 마찬가지로 ethanol추출물을 혼입(混入)한 시료의 TBA-가(價)는 다른 시료의 TBA-가(價)보다 약간 낮았었다. 4. 결론적으로 표고버섯의 용매추출물을 혼입(混入)한 시료는 저장중의 POV나 TBA-가(價) 증가추세로 볼 때 control보다 산패에 대해서 더 안정성을 보여주었다.

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황폐계류의 사방공작물 시공에 따른 저서성 대형무척추동물상의 변화 - 시공 직후의 변화를 중심으로 - (The Variation of Benthic Macroinvertebrates Caused by Erosion Control Works in a Torrential Stream - Focused on Variation of Benthic Macroinvertebrates Analyzed immediately after Construction Works -)

  • 이도형;이기환;이헌호;마호섭;배관호;김종현
    • 한국환경생태학회지
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    • 제23권4호
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    • pp.353-364
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    • 2009
  • 본 연구는 산지황폐계류에 시공한 사방공작물이 계곡생태계에 미치는 영향을 분석하고자 시공 전후를 기준으로 조사지점별로 저서성 대형무척추동물의 출현종의 변화분석 및 생물학적 수질평가를 실시하였으며, 그 결과는 다음과 같다. 시공 전 출현한 저서성 대형무척추동물의 총 수는 4문 6강 11목 22과 25종 3,086개체였으나 시공 후 조사에서는 4문 6강 10목 17과 19종 1,208개체로 감소하였다. 특히, 직접적인 사방공작물의 시공이 이루어진 조사지점에서는 시공 후 생물종이 전혀 출현하지 않거나, 극소량만이 채집되어 서식종의 현존량을 기초로 하는 다양도 지수, 풍부도 지수, 균등도 지수가 감소 또는 산출되지 않았다. 저서생물의 군집분석 결과 및 저서성 대형무척추동물의 생태점수(ESB)는 모든 조사지점에서 시공전보다 시공 후에 오수생물계열, 환경상태, 수질등급과 같은 계곡환경질이 저하된 것으로 나타났다. 즉, 시공전 상류는 양호 및 다소 양호, 중류는 다소 불량, 하류는 불량 및 매우 불량으로 분석되었으나, 시공 후 상류 일부 지역을 제외한 나머지 수역은 매우 불량으로 분석되었다. 또한 대상 계류의 수질등급의 경우 시공 전에는 $I{\sim}III$등급 사이로 분류되었으나, 시공 후 대조군을 제외하고는 모두 $IV{\sim}V$등급으로 악화되었다 이와 같이 사방공작물의 시공후 모든 조사지점에서 발생한 저서성 대형무척추동물의 서식 환경 파괴는 개체수의 감소와 수질악화로 이어졌다. 이 결과는 사방공작물의 시공 직후에 조사 분석한 것이므로, 향후 장기간의 모니터링을 통하여 시공한 사방공작물의 재해방지 효과와 함께 계류 생태계의 회복과정에 대한 지속적인 연구가 이루어져야 할 것이다.

Effects of Soy Isoflavone on Performance, Meat Quality and Antioxidative Property of Male Broilers Fed Oxidized Fish Oil

  • Jiang, S.Q.;Jiang, Z.Y.;Lin, Y.C.;Xi, P.B.;Ma, X.Y.
    • Asian-Australasian Journal of Animal Sciences
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    • 제20권8호
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    • pp.1252-1257
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    • 2007
  • This study was conducted to determine the effect of dietary soy isoflavone (ISF, 0 and 20 mg/kg) on performance, meat quality and antioxidative property in male broilers. Six replicates of 45 birds (42 d old) were used for each treatment. The birds were fed soybean meal-free diets containing 3% oxidized fish oil (acid value, 6.76 mg potassium hydroxide/g; and peroxide value, 6.18 meq/kg) for 3 wk. The results showed that average daily gain, feed intake, feed conversion and carcass traits were not affected by soy ISF. Compared with the control group, breast muscle color redness value and water holding capacity were increased (p<0.05) by ISF supplementation. The activity of plasma catalase was increased by supplementing with 20 mg ISF/kg diet. In breast muscle, Broilers fed 20 mg ISF/kg had decreased production of malondialdehyde and lactic acid. The ISF supplementation elevated total antioxidative capacity and activities of total superoxide dismutase and glutathione peroxidase. The results indicated that dietary ISF could increase redness and water holding capacity of meat, and antioxidative property of meat in male broilers fed oxidized fish oil diet.

노화 방지를 위한 한약재의 효능 연구 (I) (Age-related Changes in blood Chemistry and Thyroid hormones in Senescence Accelerated Mice(SAM R1 and SAM P6))

  • 김정숙;이제현;마진열;전원경
    • 한국한의학연구원논문집
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    • 제1권1호
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    • pp.401-418
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    • 1995
  • Aging process can be explained by many factors. In this study, we counted complete Blood Cells (CBC) such as WBC, Lymphocytes, Monocytes, Granulocytes, RBC, HGB, and HCT of both SAM P6 and SAM P1 during the aging process. Plasma albumin, glucose, alkaline phosphatase, calcium, creatinine, inorganic phosphate, urea concentrations were also measured at the same time. In addition to these, plasma concentrations of cortisol, total T3, and total T4 were analyzed by Chemiluminescent Immunoassay. There were no change in CBC counts of SAM R1 and SAM P6 during this study. Plasma concentratins of albumin and glucose decreased significantly in SAM R1. However, plasma alkaline phosphatases and creatinine concentration in SAM P6 decreased significantly at 16 week after birth comparing to the control. Total T4 levels were siginificantly increased although cortisol and total T3 concentrations were the same in SAM R1 groups. Especially, the after birth of creatinine, alkaline phosphatase, T4 of SAM P6 at 16 week were significantly different form those of SAM R1. At 12 week after birth, pilose antler extract was given 5g/kg/day p.o. for 0, 7, 14, 21, and 30 days each in both SAM R1 and SAM P6. The RBC, HGB, and HCT levels started to increase significantly from 7 days after the dose at SAM P6 only. Total T4 conectrations were elevated gradually during the study although the antler extract administration did not prevent or inhibit the increase in total T4 concentration during the study. Therefore, the elevation of erythrocytes after administration of the extract needs to be studied in future.

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플로팅 슬래브 설계와 전단연결재의 구조안전성 검토 (Examination for Structural Safety of Floating Slab Design and Shear Connector)

  • 박성재;마창남;이종호;이두화
    • 한국철도학회:학술대회논문집
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    • 한국철도학회 2011년도 정기총회 및 추계학술대회 논문집
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    • pp.374-374
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    • 2011
  • 최근 철도의 도심통과구간이나 선하역사 건설이 증가하고 있어 철도 진동과 이로 인한 2차 소음을 효과적으로 차단할 수 있는 대책이 시급히 필요하다. 지금까지 개발된 기술 가운데 가장 효과적으로 진동을 차단할 수 있는 대책은 스프링을 이용하여 궤도 전체를 하부구조와 분리시키는 플로팅 슬래브궤도 공법으로 이미 국외에서는 플로팅 슬래브궤도의 방진설계와 핵심 구성요소인 방진장치에 대한 원천기술이 확보되어 많은 부설실적을 확보하고 있으나 국내에서는 아직 시스템 설계기술과 관련 구성품 설계기술이 확보되어 있지 못하기 때문에 대부분 국외에서 개발된 시스템을 그대로 도입하고, 핵심 구성품인 방진재료는 모두 수입에 의존하는 등 관련 기술의 자립도가 매우 낮은 실정이다. 그러므로 국내외 시장에서의 기술 경쟁력을 확보하기 위해서는 플로팅 슬래브궤도 시스템 및 구성품의 설계기술을 비롯한 핵심기술의 개발이 시급하다. 본 연구에서는 기존의 연구결과를 바탕으로 시공 중 방진장치를 이용하여 슬래브를 리프팅할 때 인상 시기의 차이나 거치 후의 단차에 의해 발생되는 단면력에 대해 슬래브와 전단연결재의 구조적 안전성을 검토하였다.

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