• Journal of Family Resource Management and Policy Review
• /
• v.11 no.2
• /
• pp.43-65
• /
• 2007

This research aims at finding out how spare time activity, relationships with their children and loneliness affect the satisfaction of life of elderly people who have no spouse. To begin, according to the survey, in the case of elderly people who have no spouse, male elderly people feel more loneliness, lower unification with their offspring, and do less activity in their spare time than female elderly people. The elderly people with a higher educational level, feel less loneliness and have a close relationship with their offspring. When elderly people believe in a religion, they participate in positive activities in their spare time and have a higher satisfaction of life. Secondly, the less the elderly people have for a monthly income, the more they feel a deep sense of isolation. However, if the elderly have a sufficient monthly income, they spend their spare time on positive activities and feel a higher sense of satisfaction in their lives. These results show that economic situation is an important factor for elderly people to maintain good mental health and a good quality of life. Thirdly, the loneliness of elderly people who have no spouse was influenced by whether the elderly people have children or not. If an elderly person loses their spouse through death, they can find themselves in a desperate situation and feeling very isolated. Most elderly people who have no spouse want to live with their offspring and depend on their sons and daughters economically and psychologically. However, the elderly people living alone have lower satisfaction of life because of economic and psychological problems. Therefore, the results shows that the life satisfaction of elderly people who have no spouse was influenced by living with their children and having a close relationship with them. The elderly people who have no spouse feel hopelessness and rely increasingly on their sons and daughters. The elderly people who don't have a sufficient monthly income not only feel more loneliness than other elderly people, but are also restricted in their spare time activities. It proves that the economic situation(monthly income) is also an important factor to maintain personal relationships.

• Journal of Microbiology and Biotechnology
• /
• v.28 no.6
• /
• pp.997-1006
• /
• 2018

As shown during the 2009 pandemic H1N1 (A(H1N1)pdm09) outbreak, egg-based influenza vaccine production technology is insufficient to meet global demands during an influenza pandemic. Therefore, there is a need to adapt cell culture-derived vaccine technology using suspended cell lines for more rapid and larger-scale vaccine production. In this study, we attempted to generate a high-growth influenza vaccine strain in MDCK cells using an A/Puerto/8/1934 (H1N1) vaccine seed strain. Following 48 serial passages with four rounds of virus plaque purification in MDCK cells, we were able to select several MDCK-adapted plaques that could grow over $10^8PFU/ml$. Genetic characterization revealed that these viruses mainly had amino acid substitutions in internal genes and exhibited higher polymerase activities. By using a series of Rg viruses, we demonstrated the essential residues of each gene and identified a set of high-growth strains in MDCK cells ($PB1_{D153N}$, $M1_{A137T}$, and $NS1_{N176S}$). In addition, we confirmed that in the context of the high-growth A/PR/8/34 backbone, A/California/7/2009 (H1N1), A/Perth/16/2009 (H3N2), and A/environment/Korea/deltaW150/2006 (H5N1) also showed significantly enhanced growth properties (more than $10^7PFU/ml$) in both attached- and suspended-MDCK cells compared with each representative virus and the original PR8 vaccine strain. Taken together, this study demonstrates the feasibility of a cell culture-derived approach to produce seed viruses for influenza vaccines that are cheap and can be grown promptly and vigorously as a substitute for egg-based vaccines. Thus, our results suggest that MDCK cell-based vaccine production is a feasible option for producing large-scale vaccines in case of pandemic outbreaks.

• The Journal of Korean Academy of Prosthodontics
• /
• v.39 no.1
• /
• pp.58-70
• /
• 2001

For the successful treatment of complete denture, obtaining a good retention is essential. There are lots of factors affecting denture retention. Denture material, one of those factors affecting denture retention, was the subject of this study, and internal surface treatment also considered for the method of enhancing denture retention. Two resin(Lucitone $199^{(R)}$(heat cured resin) Vertex $CP^{(R)}$(self cured resin)) and two metal($Biosil^{(R)}$(Co-Cr alloy), $Vitallium^{(R)}$(Co-Cr alloy)) denture base materials were used for making test denture base. Newly developed device was used for measuring denture retention. After the retention was measured. We treated internal surface of test denture base with $50{\mu}m\;Al_2O_3$ powder, under 90psi, for 1 minute. Then the retention was measured again. The result was analyzed with K-S test, one-way ANOVA test and independent t-test to deter mine the significant differences as the 95% level of confidence. The results are as follows : In cases of without internal surface treatment, the retention was increased in order of $Vitallium^{(R)},\;Biosil^{(R)},\;Vertex CP^{(R)}$ and Lucitone $199^{(R)}$. Except between Vertex $CP^{(R)}$ and $Biosil^{(R)}$, retention of the other materials was significantly different (p<0.05). After the treatment of internal surface, the retention was increased in order of $Vitallium^{(R)},\;Biosil^{(R)},\;Lucno\;199^{(R)},\;Vertex\;CP^{(R)}$. Except between Lucitone $199^{(R)}$ and Vertex $CP^{(R)}$, $Vitallium^{(R)}$ and $Biosil^{(R)}$ the retention of remaining groups was significantly different each other (p<0.05). In the matter of each material, after the internal surface treatment the retention was increased with Vertex $CP^{(R)},\;Biosil^{(R)}\;and\;Vitallium^{(R)}$ and the value of differences were statistically significant. When we compare the retention of resin and metal denture base, the retention of both denture bases increased significantly with internal surface treatment, and resin denture base showed better retention. As the results show, selecting denture base material could be an important choice of complete denture treatment. To increase denture retention, internal surface treatment can be considered as a possible method.

• Journal of Radiation Protection and Research
• /
• v.29 no.2
• /
• pp.73-90
• /
• 2004

The Reg. Guide 1.109 model was reviewed against its applicability to calculating radionuclide concentrations in agricultural products for operating nuclear facilities and an improved method was proposed. The model was so modified that the radionuclides deposited since the start of operation could be considered in assessing the root uptake. Translocation factors were introduced in the equation for calculating the concentrations in edible parts due to direct plant deposition. Values specific to Korea were set up for the input parameters of the modified model. The concentrations of $^{54}Mn,\;^{60}Co,\;^{90}Sr\;and\;^{137}Cs$ in rice seeds, Chinese cabbage and radish root were calculated for various hypothetical deposition histories using the Reg. Guide 1.109 model and the modified model with parameter values in the guide and those specific to Korea put in alternately. Through comparisons among the results, it could be expected that the use of the modified model with the input of parameter values specific to Korea would result In a more resonable and realistic assessment.

• Korean journal of applied entomology
• /
• v.21 no.2 s.51
• /
• pp.61-67
• /
• 1982

The strawberry cultivar Hokowase showing rapid wilting and death around harvest time was first found in the fold at Woongcheon, Chungnam province in 1974. The fungus, Fusarium oxysporum was isolated frequently from the crown, petiole and root of strawberry plants collected from Woongcheon and was pathogenic to Hokowase. The fungus abundantly produced micro-and macro-conidia and chiamydospore on PSA. The size of micro conidia, macro conidia and Chlamydospores was $5.0\~13.0\times2.5\~3.0,\;12.8\~62.5\times2.5\times50\mu\;and\;7.5\~13.8\times5.5\~12.5\mu$, respectively. Mycelial growth of the fungus was best between $25\~30^{\circ}C$ on PSA. The disease at Woongcheon occurred from the end of March and incidence of the disease increased from the beginning of May reaching $40.2\%$ of diseased Plants at the 1st part of June. In laboratory and field evaluation tests with twelve fungicides, Difolatan, Benlate T and Tospin M showed some control effects against the disease although they did not show ignificant differences in effects compared with that of the non-treatment. The cultivar Yachiyo, Daehak 1, Line 10-2, and Senga Sengana were highly resistant, and Harunoka and Empire were moderate resistant whereas Northwest and Hokowase were highly susceptible to the fungus under field condition.

• Journal of the East Asian Society of Dietary Life
• /
• v.26 no.1
• /
• pp.25-33
• /
• 2016

The study was performed to investigate the effects of whey protein-rich meal substitute added with vitamins, minerals, and lactobacillus powder probiotics on weight loss, body fat, and body composition in 24 female volunteers for 4 weeks. Whey protein-rich meal substitute was consumed with low-fat, high calcium milk (1% fat, 260 mg/200 mL) twice a day. Subjects submitted 3-day diet records and a life-style questionnaire before the study. During the study, subjects were required to turn in a diet record every day and consume the meal substitute formula in the metabolic ward at C university for 4 weeks. Anthropometric measurements were carried out weekly by Inbody 7.0. The dietary intake and anthropometric data were analyzed to compare changes before and after the study by paired t-test with SPSS version 23.0. The subjects were mostly early 20's and either overweight or obese and highly motivated to lose weight. Most of the subjects consumed three meals per day regularly and spent mostly 10~15 minutes for a meal. Their caloric intake was relatively low and decreased from 1,360 kcal at week 0 to 1,100 kcal after 4 weeks. However, total protein intake increased while carbohydrate and fat intakes decreased (p<0.05) after the trial. Nine vitamin intakes after the study improved compared to those before the study (p<0.05). After the study, subjects showed lower body weight (-1.8 kg), body fat (-0.94 kg), percent body fat (-0.86%), as well as waist circumference (-4.52 cm), hip circumference (-0.44 cm), waist hip ratio (-0.05), and triceps skinfold thickness (-2.39 mm) compared to those at week 0 (p<0.05). Muscle mass tended to be less compared to week 0, although there was no significant differences between weeks 0 and 4. In conclusion, diet trial with whey protein-rich meal substitute induced weight loss and positively changed body fat parameters and body composition.

• Spatial Information Research
• /
• v.1 no.1
• /
• pp.39-53
• /
• 1993

A geographical information systems(GIS) was a useful aid in the assessment of urban nonpoint source pollution and the development of a pollution control strategy. The GIS was used for data integration and display, and to provide data for a nonpoint source model. An empirical nonpoint source loading model driven by land use was used to estimate pollutant loadings of priority pollutant. Pollutant loadings were estimated at fine spatial resolution and aggregated to storm sewer drainage basins(sewershedsl. Eleven sewersheds were generated from digital versions of sewer maps. The pollutant loadings of individual land use polygons, derived as the unit of analysis from street blocks, were aggregated to get total pollutant loading within each sewershed. Based on the model output, a critical sewershed was located. Pollutant loadings at major sewer junctions within the critical sewershed were estimated to develop a mi t igat ion strategy. Two approaches based on the installat ion of wet ponds were investigated -- a regional approach using one large wet pond at the major sewer outfall and a multi-site approach using a number of smaller sites for each major sewer junction. Cost analysis showed that the regional approach would be more cost effective, though it would provide less pollution control.

• The Bulletin of The Korean Astronomical Society
• /
• v.37 no.2
• /
• pp.207.1-207.1
• /
• 2012

One of the key aspects of the upcoming Ultra-Fast Observatory (UFFO) Pathfinder for Gamma-Ray Bursts(GRBs) identification will be the UFFO Burst Alert & Trigger Telescope(UBAT), based on a novel space telescope technique. The UBAT consists of coded mask, hopper, and detector module(DM). The UBAT DM consists of YSO crystal arrays, multi-anode photo mulipliers, and readout electronics. We will present the design and construction of the UBAT DM, and the response of the UBAT DM to X-ray sources.

• Korean Journal of Plant Resources
• /
• v.25 no.1
• /
• pp.1-6
• /
• 2012

Atopic dermatitis is a chronic, allergic inflammatory skin disease that is accompanied by pruritic chronic eczema and markedly increased levels of inflammatory cells in endothelial cells. Arctium lappa L. is a popular edible vegetable cultivated in Asia. This study examined the effect of butanol extracts of A. lappa (ALBE) on the expression of adhesion molecule, ICAM-1 and the production of NO-iNOS induced by TNF-alpha in A549 endothelial cells. We also studied the effects of ALBE on the proliferation of keratinocyte. We observed significant inhibition of NO-iNOS production in dose-dependant manners and ALBE at $100\;{\mu}g$/mL suppressed the expression of ICAM-1 in TNF-${\alpha}$-induced A549 cells. In addition, the treatment of ALBE for 48 hrs increased the proliferation of HaCaT keratinocytes. These results support that ALBE has an anti-inflammatory effects for the treatment of atopic dermatitis.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
• /
• 1999.11a
• /
• pp.157-161
• /
• 1999

본 연구에서 직물의 열, 수분 전달특성과 KES-FB의 역학적 특성치, 직물표면의 fractal dimension을 측정하여 주관적 의복 착용 쾌적감을 예측하고자 하였다. 실험의복에 사용된 직물은 면 100% 평직물, 면/PET 혼방직물, 피치가공된 면/PET 혼방직물, PET 100% 평직물, 알칼리 감량가공된 PET 100% 크레이프 직물이었으며, 실험의복의 형태는 긴 소매 셔츠로 하였다. 착용실험은 온도 29$\pm$0.5$^{\circ}C$, 상대습도 75$\pm$2%RH, 기류 0.15m/s를 유지하는 항온항습실에서 실시하였고 36명의 여성 피험자(20-23세)들이 참여하였다. 의복 착용감의 하위 구성차원을 파악하기 위해 실험결과를 요인분석한 결과 5 개의 요인으로 추출되었다. 제 1 요인은 체온상승, 수분특성과 관련이 있는 온열.발한감이었으며, 제 2 요인은 무게ㆍ두께감, 제 3 요인은 회복특성감, 제 4 요인은 표면접촉감, 제 5 요인은 온냉감으로 구성되었다. 직물의 표면특성을 정량화하는 방법으로 도입한 fractal dimension 의 분석값들과 종래의 가장 보편적으로 이용되어 온 KES_FB 의 표면 특성치들이 주관적 착용쾌적감 예측에 얼마나 기여하는지 비교해 본 결과, 표면접촉감은 fractal dimension, 접촉점들의 총면적, 접촉점들의 평균 axis ratio, MMD, SMD와 높은 상관을 나타내었다. 또한 종합적 착용쾌적감에 대해서는 SMD 를 제외한 척도들이 유의한 상관을 보였으며, 그 중에서도 fractal dimension 과 접촉점들의 총면적은 0.8 이상의 높은 상관을 나타내었다. 착용쾌적감을 예측하기 위한 회귀분석결과에서는 fractal dimension 만으로 쾌적감의 74%가 설명되었으며 공기 투과도를 첨가하면 두 변수로 $R^2$=.792가 되었다. 설명되는 누적분산값은 67.18%였다.주관적 평가의 결과와 객관적 평가 결과를 이용해 마직물의 태를 평가하는 산출식을 제시하였다. 태 평가치의 경우 16가지 특성치를 모두 넣는 방법과 stepwise 방법, 또 Kawabatark 사용한 순차적 군 회귀법의 세가지 방법의 회귀식 중 16가지 특성치를 모두 넣는 방법의 결정계수가 가장 높았다.tosterone농도는 107.7$\pm$12.0 pmol／l이었고, 남성의 타액내 농도는 274.2$\pm$22.1 pmol／l이었다. 이상의 결과로 보아 본 연구에서 정립된 EIA 방법은 RIA를 대신하여 소규모의 실험실에서도 활용할 수 있을 것으로 사려된다.또한 상실기 이후 배아에서 합성되며, 발생시기에 따라 그 영향이 다르고 팽창과 부화에 관여하는 것으로 사료된다. 더욱이, 조선의 ${\ulcorner}$구성교육${\lrcorner}$이 조선총독부의 관리하에서 실행되었다는 것을, 당시의 사범학교를 중심으로 한 교육조직을 기술한 문헌에 의해 규명시켰다.nd of letter design which represents -natural objects and was popular at the time of Yukjo Dynasty, and there are some documents of that period left both in Japan and Korea. "Hyojedo" in Korea is supposed to have been influenced by the letter design. Asite- is also considered to have been "Japanese Letter Jobcheso." Therefore, the purpose of this study is to look into the origin of the letter designs in t