• Clinical and Experimental Pediatrics
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• 제50권5호
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• pp.422-429
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• 2007

Measurement of lung function is an integral component of respiratory physiology and of clinical assessment of lung diseases in school age children and adults. Pulmonary function test of infants and children under the age of 2 years have now been standardised and are being used both in research and as an adjunct to clinical management. By contrast, until recegntly, children of preschool age, i.e. between 2-6 years represented a major challenge for pulmonary function test assessment, this particular period commonly being referred to as the 'dark ages' of Pediatric Pulmonology. Measurement of lung function in preschool-aged children is now feasible. However, much work remains to be done in standardizing how these tests are performed, and in understanding the most appropriate role for the various tests in the study of growth and development of the respiratory system and in the clinical management of children in this age group. As the field develops and the knowledge of respiratory physiology in this age group expands, investigation of different and more appropriate algorithm use in preschool children, together with development of more appropriate reference data, may result in improved disease discrimination.

• 한국방사선학회논문지
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• 제17권5호
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• pp.767-773
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• 2023

본 연구에서는 폐용적에 영향을 미치는 관련 인자들과 폐기능 환기장애에 대한 유의성을 평가하고자 하였다. 실험대상으로는 저선량 흉부 CT검사와 폐활량검사를 동시에 수행한 정상 성인 남·여 206명을 선정하였으며 실험방법으로는 저선량 흉부 CT검사로 획득한 폐 CT 영상을 이용하여 폐용적을 딥러닝 기반의 AVIEW LCS 자동진단 프로그램을 이용하여 측정하였다. 그리고 폐활량계를 이용하여 폐기능을 측정한 결과를 획득하였으며 폐용적에 영향을 미치는 관련 인자로 성별 및 BMI를 선정하여 폐용적과의 독립표본 T-test를 통하여 유의성을 평가하고자 하였다. 실험결과 성별에 따른 폐용적의 평가에서 남성의 모든 폐용적이 여성의 모든 폐용적보다 크다는 것을 확인할 수 있었다. 성별 및 폐용적에 대한 각각의 평균값을 이용한 독립표본 T-test 결과 남성이 여성보다 모든 폐용적이 더 크다는 결과는 유의한 결과를 나타내었다(p<0.001). 그리고 BMI 지수에 따른 폐용적의 평가에서 BMI 지수 24 이상의 성인의 모든 폐용적이 BMI 지수 24 미만의 모든 폐용적보다 크다는 것을 확인할 수 있었다. 그러나 BMI 지수 및 폐용적에 대한 각각의 평균값을 이용한 독립표본 T-test 결과 BMI 지수 24 이상이 BMI 지수 24 미만보다 모든 폐용적이 더 크다는 결과는 유의한 결과를 나타내지 않았다(p<0.055). 폐기능 환기장애 유무에 따른 폐용적의 평가에서 폐기능 환기 정상성인의 모든 폐용적이 폐기능 환기 장애성인의 모든 폐용적보다 크다는 것을 확인할 수 있었다. 그리고 폐기능 환기장애 유무 및 폐용적에 대한 각각의 평균값을 이용한 독립표본 T-test 결과 폐기능 환기 정상성인이 폐기능 환기 장애성인보다 모든 폐용적이 더 크다는 결과는 유의한 결과를 나타내었다(p<0.001). 폐용적과 폐활량 검사 결과는 폐 건강을 평가하는데 가장 중요한 지표이며, 이 두 지표를 함께 사용하여 폐 기능을 평가하는 것이 가장 정확한 평가 방법이다. 그러므로 본 연구에서는 폐용적과 폐활량 검사에 대한 향후 유사 연구 시 폐기능 환기 정상 성인과 폐기능 환기 장애 성인에 대한 폐용적 평균값을 제시하여 기초자료로 활용될 것이라고 사료된다.

• Tuberculosis and Respiratory Diseases
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• 제82권4호
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• pp.311-318
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• 2019

Background: Although physical activity is known to be beneficial to lung function, few studies have been conducted to investigate the correlation between physical activity and lung function in dusty areas. Therefore, the purpose of this study is to investigate the correlation between physical activity and lung function in a Korean cohort including normal and COPD-diagnosed participants. Methods: Data obtained from the COPD in dusty areas (CODA) cohort was analyzed for the following factors: lung function, symptoms, and information about physical activity. Information on physical activity was valuated using questionnaires, and participants were categorized into two groups: active and inactive. The evaluation of the mean lung function, modified Medical Research Council dyspnea grade scores, and COPD assessment test scores was done based on the participant physical activity using a general linear model after adjusting for age, sex, smoking status, pack-years, height, and weight. In addition, a stratification analysis was performed based on the smoking status and COPD. Results: Physical activity had a correlation with high forced expiratory volume in 1 second ($FEV_1$) among CODA cohort (p=0.03). While the active group exhibited significantly higher $FEV_1$ compared to one exhibited by the inactive group among past smokers (p=0.02), no such correlation existed among current smokers. There was no significant difference observed in lung function after it was stratified by COPD. Conclusion: This study established a positive correlation between regular physical activity in dusty areas and lung function in participants.

• Journal of Chest Surgery
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• 제28권4호
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• pp.371-375
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• 1995

Surgical resection of lung cancer or other disease is recently required in patients with severely impaired lung function resulting from chronic obstructive pulmonary disease or disease extension. So prediction of pulmonary function after lung resection is very important in thoracic surgeon. We studied the accuracy of the prediction of postoperative pulmonary function using perfusion lung scan with 99m technetium macroaggregated albumin in 22 patients who received the pneumonectomy. The linear regression line derived from correlation between predicting[X and postoperative measured[Y values of FEV1 and FVC in patients are as follows: 1 Y[ml =0.713X + 381 in FEV1 [r=0.719 ,[P<0.01 2 Y[ml =0.645X + 556 in FVC [r=0.675 ,[P<0.01 In conclusion,the perfusion lung scan is noninvasive and very accurate for predicting postpneumonectomy pulmonary function.

• 대한물리의학회지
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• 제7권3호
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• pp.267-274
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• 2012

Purpose : The purpose of this study was to investigate characteristics of the forced pulmonary function test effect by changes in lung function related to postures and by Transverse Abdominis(TrA). Contraction in standing position during forced inspiration and expiration with young female adults. Methods : 10 young female adults were recruited this study. pulmonary Function test was measured with a Master-screen Body (VIASYS Inc., CA, 미국). To check the changes in lung function with different postures, we tested pulmonary function in the standing and supine position each. In the standing position, while the transversus abdominis was activating, we compared the forced inspiration with the forced expiration. Statistical analysis was used Independent t-test to know difference between forced inspiration and expiration of activated TrA. Results : According to the study, the change of pulmonary function were statistically significant difference in the standing compared to the supine position. The contraction of the transversus abdominis causes decrease in the change of forced inspiration and increase in the change of forced expiration. Conclusion : These results indicate that spontaneous contraction of the TrA in standing position helps pulmonary function. And the selective contraction of the transversus abdominis at the end of forced inspiration makes increases in the forced expiration.

• 한국산업보건학회지
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• 제24권2호
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• pp.130-136
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• 2014

Objectives: To evaluate the pulmonary toxicity of Korean Chrysotile(KC), the lung function and the number of fibers in the bronchoalveolar lavage fluid of Sprague-Dawley rats instilled with KC were estimated. Materials: Rats were administered 1 mg KC by a single intratracheal instillation. At each time point(5 days, 5 weeks, 10 weeks), the lung function of the rats was analyzed by pressure transducer and the amount of asbestos in the bronchoalveolar lavage fluid of the rats was calculated by transmission electron microscope equipped with energy dispersive X-ray spectrometer. Results: The lung function of the rats at 5 days after instillation of KC was confirmed to be degraded. However, after 5 weeks the test groups showed a tendency to recover lung function. Still, after 10 weeks the lung function of the test groups had not recovered completely. The number of fibers in the bronchoalveolar lavage fluid of the rats instilled with KC rapidly decreased. At 5 weeks the number of fibers had reduced to approximately 1/2 of that found at 5 days. Over time, at 10 weeks it had rapidly decreased to 1/100 that found at 5 days. Conclusions: Korean chrysotile fibers rapidly decreased in the lungs of rats, but the lung function of rats instilled KC does had not completely recovered by 10 weeks.

• The Journal of Korean Physical Therapy
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• 제36권2호
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• pp.67-70
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• 2024

Purpose: This study investigated the effect of virtual reality and Schroth breathing exercises on the lung function characteristics of normal adults in their 20s. Methods: The subjects were randomly divided into groups with ten people each in the experimental groups, namely the virtual reality breathing exercise group (BBEG) and the Schroth breathing exercise group (SBEG), and the control group. The experimental groups performed each breathing exercise for 4 weeks. Subsequently, pulmonary function test indicators such as the forced vital capacity (FVC) and the forced expiratory volume (FEV1) were measured. Results: In the within-group comparison of the subjects before and after the exercises, there was a significant difference in the FVC and FEV1 (p<0.05), but there was no significant difference in FEV1/FVC. The result of the difference test between groups showed that there was a significant difference in FEV1/FVC after exercise (p<0.05). However, there were no significant differences in the remaining items (p>0.05). Conclusion: Improvement in lung function was seen in both exercise groups, and the changes in FEV1/FVC indicated significant improvement in the lung function of the experimental groups compared to the control group.

• 종양간호연구
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• 제10권1호
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• pp.95-102
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• 2010

Purpose: The aim of this study was to evaluate the effect of a breathing exercise intervention by measuring pulmonary function test (PFT) three times; preoperative, 3rd and 5th day after operation. Methods: This study was designed as a non-equivalent control group pretest-posttest design. A total of 55 patients with lung cancer were recruited from a Chonnam university hospital in Hawsun-gun, Korea from January to December 2008. Results: 'Forced Vital Capacity (FVC)' and 'Forced Expiratory Volume in 1 second $(FEV_1)$' were significantly improved in the experimental group than those in the control group (p<.05). Conclusion: Breathing exercise intervention was found to be effective in improving pulmonary function among lung cancer patients underwent lung lobectomy. Thus, the breathing exercise can be applied in hospitals and communities for patients with lung cancer as one of the nursing intervention modalities for their better postoperative rehabilitation.

• Journal of Chest Surgery
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• 제33권10호
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• pp.798-805
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• 2000

Background : the prediction on changes in the lung function after lung surgery would be an important indicator in terms of the operability and postoperative complications. In order to predict the postoperative FEV1 - the commonly used method for measuring changes in lung function- a comparison between the quantitative CT and the perfusion lung scan was made and proved its usefulness. Material and Method : The subjects included 22 patients who received perfusion lung scan and quantitative CT preoperatively and with whom the follow-up of PFT were possibles out of the pool of patients who underwent right lobectomy or right pneumonectomy between June of 1997 and December of 1999. The FEV1 and FVC were calibrated by performing the PFT on each patient and then the predicted FEV1 and FVC were calculated after performing perfusion lung scan and quantitative CT postoperatively. The FEV1 and FVC were calibrated by performing the PFT after 1 week and after 3 momths following the surgery. Results : There was a significant mutual scan and the actual postoperative FEV1 and FVC at 1 week and 3 months. The predicted FEV1 and FVC(pneumonectomy group : r=0.962 and r=0.938 lobectomy group ; r=0.921 and r=913) using quantitative CT at 1 week postoperatively showed a higher mutual relationship than that predicted by perfusion lung scan(pneumonectomy group : r=0.927 and r=0.890 lobectomy group : r=0.910 and r=0.905) The result was likewise at 3 months postoperatively(CT -pneumonectomy group : r=0.799 and r=0.882 lobectomy group : r=0.934 and r=0.932) Conclusion ; In comparison to perfusion lung scan quantitative CT is more accurate in predicting lung function postoperatively and is cost-effective as well. Therefore it can be concluded that the quantitative CT is an effective method of replacing the perfusion lung scan in predicting lung function post-operatively. However it is noted that further comparative analysis using more data and follow-up studies of the patients is required.

• Journal of Chest Surgery
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• 제28권12호
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• pp.1096-1106
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• 1995

We experienced 7 cases of left single lung transplantation in 14 mongrel dogs and analyzed graft lung function by hemodynamics, blood gas analysis, chest X-ray, biopsy and perfusion lung scan. We performed right pulmonary artery cuff[PA cuff for analysis of graft lung function in 3 cases. The donor lungs were flushed with modified Euro-Collins solution[n=3 or low potassium dextran glucose solution[n=4 and preserved for 4 to 5 hours[n=4 or 24 hours[n=3 at 10o C and implanted to the dogs with similar weight . Assessment of left graft lung was done by occluding the right pulmonary artery for 10 minutes using PA cuff. Assessment for graft lung function was done immediately after an operation and after 3 days, 7days and 3 weeks postoperatively. Four dogs survived for 3days, 7days[2 cases and 3 weeks respectively. Other three dogs expired within 3 hours of reperfusion. Immediate perfusion scans of left lung in four survived dogs after reperfusion were 42.1%, 36% , 11% and 5.9% respectively, and another dog with 4.8% perfusion to left lung was dead due to left atrial thrombi after 3 hours reperfusion. In one case among three acute rejections follow-up perfusion scan was done on 3rd and 11th postoperative day and the result decreased from 36% perfusion immediate postoperatively to 21% and 15% respectively. Three expired dogs postoperatively couldn`t tolerate occlusion of right pulmonary artery with above 40 mmHg of mean pulmonary artery pressure. On the other hand, three survival dogs postoperatively tolerated occlusion of right pulmonay artery with less than 30 mmHg of mean pulmonary artery pressure. and one dog couldn`t tolerate same procedure immediate postopertively but in 2 hours reperfusion later tolerated with 29 mmHg of mean pulmonary artery pressure.In conclusion we couldn`t compare the effect of two flushing solutions but low potassium dextran glucose solution showed relatively safe preservation effect in cases with preservation of more than 20 hours. Also canine left single lung transplantation model with PA cuff indicated useful method for the assessment of graft lung function with effect of lung preservation.