• Tuberculosis and Respiratory Diseases
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• 제74권1호
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• pp.15-22
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• 2013

Background: Differentiating cardiogenic pulmonary edema from other bilateral lung diseases such as pneumonia is frequently difficult. We conducted a retrospective study to identify predictors for cardiogenic pulmonary edema and non-cardiogenic causes of bilateral lung infiltrates in chest radiographs. Methods: The study included patients who had newly developed bilateral lung infiltrates in chest radiographs and patients who underwent echocardiography. Cases were divided into two groups based on the echocardiographic findings: the cardiogenic pulmonary edema group and the non-cardiogenic group. Clinical characteristics and basic laboratory findings were analyzed to identify predictors for differential diagnosis between cardiogenic and non-cardiogenic causes of bilateral chest infiltrates. Results: We analyzed 110 subjects. Predictors of cardiogenic pulmonary edema were higher brain natriuretic peptide (BNP) levels, lower C-reactive protein (CRP) levels on the day of the event (<7 mg/dL), age over 60 years, history of heart disease, and absence of fever and sputum. CRP on the day of the event was an independent factor to differentiate cardiogenic and non-cardiogenic causes of newly developed bilateral chest infiltrates. Also, the validity was comparable to BNP. Conclusion: Clinical symptoms (sputum and fever), medical history (dyslipidemia and heart disease), and laboratory findings (BNP and CRP) could be helpful in the differential diagnosis of patients with acute bilateral lung infiltrates in chest radiographs.

• Tuberculosis and Respiratory Diseases
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• 제72권2호
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• pp.223-227
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• 2012

Pulmonary siderosis, or Welder's lung disease is an occupational lung disease caused by iron-inhalation. Diagnosis of pulmonary siderosis is based on occupational history of the patient, radiologic findings, and pathologic findings of iron-laden macrophages within lung tissue or broncho-alveolar lavage fluid. We observed a case of a 43 years-old welder diagnosed with pulmonary siderosis via thoracoscopic lung biopsy. Sputum culture along with pathology also identified a non-tuberculotic mycobacterial infection with a sputum culture and the pathologic findings. The patient was treated with anti-tubercular medication and cessation of iron-exposure. And his condition improved within a few months.

• Tuberculosis and Respiratory Diseases
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• 제75권3호
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• pp.120-124
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• 2013

Herein, we report a case of multiple systemic arteries to pulmonary artery fistulas without any underlying causes, presenting recurrent hemoptysis. Transcatheter embolization was successfully performed several times on multiple systemic feeding arteries. Multiple systemic arteries to pulmonary fistulas can be a source of uncontrolled bleeding, and embolization may be a reasonable therapeutic option to control the bleeding.

• Tuberculosis and Respiratory Diseases
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• 제45권3호
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• pp.604-608
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• 1998

Von Recklinghausen병에 동반되는 악성종양은 주로 신경섬유육종이지만 드물게는 폐암이 동반되는 경우가 보고되고 있고 ras 유전자가 양 질환의 발생에 영향이 있음이 알려져 있어 앞으로 이에 관한 연구가 필요하리라 생각된다.

• Tuberculosis and Respiratory Diseases
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• 제71권2호
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• pp.139-143
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• 2011

Small bowel metastasis of pleomorphic carcinoma of the lung is very rare. A 58-year-old man was admitted to our hospital with abdominal palpable mass in the right upper quadrant area. He underwent right middle and lower lobectomy for early stage pleomorphic carcinoma of the lung approximately 3 months ago. USG-guided biopsy was performed for abdominal mass. Pathologic examination revealed a metastatic pleomorphic carcinoma from the lung. He received chemotherapy followed by radiation therapy but died due to septic shock caused by intestinal stenosis and adhesion. We report the first case of small bowel metastasis by pleomorphic carcinoma of the lung after curative surgery.

• Tuberculosis and Respiratory Diseases
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• 제52권5호
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• pp.550-556
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• 2002

Microscopic polyangiitis is a systemic small-vessel vasculitis that is associated primarily with necrotizing glomerulonephritis and pulmonary capillaritis. A recurrent and diffuse alveolar hemorrhage due to pulmonary capillaritis is the main clinical manifestation of lung involvement. Recently, and interstitial lung disease that mimics idiopathic pulmonary fibrosis was reported to be rarely associated with microscopic polyangiitis. Here we report two patients with microscopic polyangiitis who showed a honeycomb lung at the time of the initial diagnosis with a brief review of relevant literature.

• Tuberculosis and Respiratory Diseases
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• 제80권4호
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• pp.351-357
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• 2017

In 2011, a cluster of peripartum patients were admitted to the intensive care unit of a tertiary hospital in Seoul with signs and symptoms of severe respiratory distress of unknown etiology. Subsequent epidemiological and animal studies suggested that humidifier disinfectant (HD) might represent the source of this pathology. Epidemiological studies, animal studies, and dose-response analysis demonstrated a strong association between HD use and lung injuries. The diagnostic criteria for HD-associated lung injury (HDALI) was defined on the basis of the clinical, pathological, and radiological attributes of the patients. The clinical spectrum of HDALI appears to range from asymptomatic to full-blown acute respiratory failure, and some patients have required actual lung transplantation for survival. The overall mortality of the exposed population was not significant, although peripartum patients and children who were admitted to the intensive care unit did show high mortality rates. Persistent clinical findings such as diffuse ill-defined centrilobular nodules and restrictive lung dysfunction were observed in some of the survivors. The findings of this review emphasize the importance of assessment of the level of toxicity of chemical inhalants utilized in a home setting, as well as the need to identify and monitor afflicted individuals after inhalational injury.

• Tuberculosis and Respiratory Diseases
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• 제54권5호
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• pp.570-573
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• 2003

폐에 발생하는 육종양암종은 매우 드문 악성 폐종양으로 예후가 좋지 않은 것으로 알려져 있다. 저자들은 운동시 호흡곤란을 주소로 내원한 환자에서 경피적세침폐생검으로 확진한 육종양암종 1예를 경험하였기에 보고하는 바이다.

• Tuberculosis and Respiratory Diseases
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• 제87권1호
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• pp.40-51
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• 2024

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrosing interstitial pneumonia with a very poor prognosis. Accurate diagnosis of IPF is essential for good outcomes but remains a major medical challenge due to variability in clinical presentation and the shortcomings of existing diagnostic tests. Medical history collection is the first and most important step in the IPF diagnosis process; the clinical probability of IPF is high if the suspected patient is 60 years or older, male, and has a history of cigarette smoking. Systemic assessment for connective tissue disease is essential in the initial evaluation of patients with suspected IPF to identify potential causes of interstitial lung disease (ILD). Radiologic examination using high-resolution computed tomography plays a pivotal role in the evaluation of patients with ILD, and prone and expiratory computed tomography images can be considered. If additional tests such as surgical lung biopsy or transbronchial lung cryobiopsy are needed, transbronchial lung cryobiopsy should be considered as an alternative to surgical lung biopsy in medical centers with experience performing this procedure. Diagnosis through multidisciplinary discussion (MDD) is strongly recommended as MDD has become the cornerstone for diagnosis of IPF, and the scope of MDD has expanded to monitoring of disease progression and suggestion of appropriate treatment options.

• 대한영상의학회지
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• 제85권4호
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• pp.714-726
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• 2024

흉부 CT상 폐기종이나 간질성 폐질환의 형태나 범위를 인공지능을 이용하여 자동적으로 객관적으로 진단하는 다양한 알고리즘을 개발되고, 이를 증명하는 연구들이 진행되어 왔다. 흉부 CT상 인공지능을 이용한 폐기종 정량화 연구들을 보면 CT상 폐기종의 상대적인 양이 증가와 폐 기능의 악화와 연관이 있으며, 특히 중심성 폐기종을 중심으로 정량화를 하는 것이 임상 증상이나 만성폐쇄성 폐질환의 사망률을 예측하는 데 도움이 된다고 보고하고 있다. 또한, 간질성 폐질환에서는 인공지능이 CT상 통상성 간질성 폐렴의 형태를 정상, 간유리 음영, 망상형 음영, 벌집 모양, 폐기종, 경화로 분류를 할 수 있고, 인공지능이 흉부영상의학과 전문의와 비슷한 정도로 통상성 간질성 폐렴을 진단(70%-80%) 할 수 있다고 보고했다. 그러나 인공지능의 결과들이 흉부 CT의 스캔 변수들, 재구성 알고리즘, 방사선 선량, 개발된 인공지능 훈련 데이터에 의해 영향을 받으며, 이러한 이유로 아직까지 흉부 CT상 폐기종과 간질성 폐질환의 진단과 정량화는 실제로 일상 업무에서 제한적으로 사용되고 있다. 이 논문에서는 폐기종과 간질성 폐질환의 진단과 정량화를 위해서 인공지능을 사용하고 있는 저자들의 경험을 증례로 소개를 하고, 이 두 질환의 인공지능의 효용성과 제한점에 대해서 언급하고자 한다.