• Journal of Korean Neurosurgical Society
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• 제59권1호
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• pp.62-64
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• 2016

Cerebrospinal fluid leakage may commonly occur during spinal surgeries and it may cause dural tears. These tears may result in hemorrhage in the entire compartments of the brain. Most common site of such hemorrhages are the veins in the cerebellar region. We report a case of hemorrhage, mimicking aneurysmal subarachnoid hemorrhage due to a cerebrospinal fluid leakage following lumbar spinal surgery and discuss the possible mechanisms of action.

• 한국방사선학회논문지
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• 제14권5호
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• pp.715-723
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• 2020

요추 자기공명 검사 시 병변 호발 부위인 Lumbar 4-5번, Sacrum 1번의 축상 영상 검사에서 인접한 두 그룹의 슬라이스 겹침으로 Cross-Talk 인공물이 발생한다. 이로 인해 병변 판독 시 문제점이 발생한다. 본 연구에서는 최적의 분할 TR의 적용을 통해서 Cross-Talk 인공물을 완벽히 제거하고자 한다. 관심 영역은 지방(ROI 1), 척추 기립근 바깥쪽(ROI 2), 척추 기립근 안쪽(ROI 3), 가시돌기(ROI 4)로 나눠 평균화하여 계측하였다. 신호 강도(SI)는 ROI 1의 경우 C4에서 163.43 ± 25.08, ROI 2, ROI 3은 C6에서 각각 67.89 ± 11.75, 69.99 ± 10.91, ROI 4는 C5에서 70.65 ± 27.21을 나타내었다(p<0.000). 신호 대 잡음 비(SNR)는 분할 TR 6에서 SNR 1, 2, 3, 4 값이 각각 135.45 ± 35.90, 56.92 ± 15.90, 58.77 ± 15.59, 54.91 ± 118.95로 나타났다(p<0.000). 대조도 대 잡음비(CNR)는 분할TR 6에서 CNR1, CNR2, CNR3, 값이 각각 78.52 ± 24.11, 76.67 ± 24.38, 80.54 ± 26.33로 나타났다(p<0.000). 시간 대비 최적의 분할 TR 값은 6이며, 이를 T1 축상면 영상에 적용한다면 인공물 저감화에 도움이 되리라고 판단된다.

• 대한수의학회지
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• 제30권4호
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• pp.401-406
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• 1990

A female Holstein calf with five legs and two tails was examined macroscopically and radiographically. The external feature included two normal forelimbs, two normal hindlimbs, a normal tail and each of underdeveloped extra hindlimb and tail, which was attached to the pelvic region. The extra hindlimb consisted of an underdeveloped femur, crural meromelia, duplicated calcaneous, partially duplicated metatarsal bone, three rows of digits with hoofs. This extra hindlimb was connected to an extra os coxa. The cervical and thoracic vertebrae were fused partially. The lumbar, sacral and coccygeal vertebrae were duplicated. This calf is a dipygus associated with pygopagus parasiticus.

• 대한물리의학회지
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• 제11권2호
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• pp.13-16
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• 2016

PURPOSE: The Fukuda test can be used at home and in school to diagnose scoliosis at an early stage and prevent serious curvature of the spine. This study aimed to use the Fukuda test to detect scoliosis. An additional aim was to invoke the national interest in imbalanced postures and habits, which result in scoliosis, by providing data obtained in periodic assessments. METHODS: The study consisted of 35 idiopathic scoliosis patients (22 in right lumbar spinal region and 13 in the left lumbar spinal region). The distance of displacement and angle of displacement were measured following the Fukuda test. A correlation analysis was then used to examine the distance of displacement and angles of displacement and rotation with regard to the direction of the curve in scoliosis. RESULTS: There was a significant negative correlation (p<0.00) between the direction of the curve in scoliosis and the angle of displacement, but there was no correlation between the cobb's angle and distance of displacement or between the cobb's angle and angle of rotation. CONCLUSION: The Fukuda test did not capture changes in spinal curvature such as the cobb's angle, or subsequent changes in the muscles. Thus, the Fukuda test is not suited to examining the direction or status of the thoracic curve in scoliosis patients. Simple methods to objectively measure scoliosis need to be developed.

• Journal of Korean Neurosurgical Society
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• 제61권4호
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• pp.434-440
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• 2018

Objective : The purpose of this study was to find an optimal delivery route for clinical trials of intrathecal cell therapy for spinal cord injury in preclinical stage. Methods : We compared in vivo distribution of Cy5.5 fluorescent dye in the spinal cord region at various time points utilizing in vivo optical imaging techniques, which was injected into the lateral ventricle (LV) or cisterna magna (CM) of rats. Results : Although CM locates nearer to the spinal cord than the LV, significantly higher signal of Cy5.5 was detected in the thoracic and lumbar spinal cord region at all time points tested when Cy5.5 was injected into the LV. In the LV injection Cy5.5 signal in the thoracic and lumbar spinal cord was observed within 12 hours after injection, which was maintained until 72 hours after injection. In contrast, Cy5.5 signal was concentrated at the injection site in the CM injection at all time points. Conclusion : These data suggested that the LV might be suitable for preclinical injection route of therapeutics targeting the spinal cord to test their treatment efficacy and biosafety for spinal cord diseases in small animal models.

• Journal of Korean Neurosurgical Society
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• 제29권4호
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• pp.574-579
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• 2000

Chordomas are rare central nervous system tumors that are found predominantly in the sacrococcygeal(50%) and basiosphenoidal region(35%). Most of the remainder are related to the vertebral bodies and only 1 to 2% of them are known to occur in the thoracic vertebrae. A 15-year-old girl was admitted because of paraparesis. Three months prior to admission, she underwent a lumbar laminectomy at other hospital for the treatment of herniated lumbar disc but paraparesis became rather aggravated after the operation. At admission, MRI showed a low signal T1WI, high signal T2WI mass compressing the cord at T2 vertebral body. The tumor was subtotally removed via costotransversectomy but as the tumor was proven to be a chordoma, a second stage operation via anterior route was followed. At second operation, T2 corpectomy and T1-T3 plate fixation with autogeneous ileac bone graft was performed. Shortly after the operation, preoperative paraparesis disappeared completely and no evidence of tumor recurrence was noticed both clinically and radiologically for next 2 years. Spine surgery at cervicothoracic junction may be technically demanding due to anatomical complexity and hindering large vessels. The authers reviewed this case with special emphasis on the surgical procedure in this region.

• Journal of Ginseng Research
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• 제43권1호
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• pp.58-67
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• 2019

Background: Diabetic neuropathy is one of the most devastating ailments of the peripheral nervous system. Neuropathic pain develops in ~30% of diabetics. Here, we examined the suppressive effect of GS-KG9 on neuropathic pain induced by streptozotocin (STZ). Methods: Hyperglycemia was induced by intraperitoneal injection of STZ. Rats showing blood glucose level > 250 mg/dL were divided into five groups, and treatment groups received oral saline containing GS-KG9 (50 mg/kg, 150 mg/kg, or 300 mg/kg) twice daily for 4 wk. The effects of GS-KG9 on pain behavior, microglia activation in the lumbar spinal cord and ventral posterolateral (VPL) nucleus of the thalamus, and c-Fos expression in the dorsal horn of the lumbar spinal cord were examined. Results: The development of neuropathic pain began at Day 5 and peaked at Week 4 after STZ injection. Mechanical and thermal pains were both significantly attenuated in GS-KG9-treated groups from 10 d after STZ injection as compared to those in the STZ control. GS-KG9 also repressed microglia activation in L4 dorsal horn and VPL region of the thalamus. In addition, increase in c-Fos-positive cells within L4 dorsal horn lamina I and II of the STZ control group was markedly alleviated by GS-KG9. Conclusion: These results suggest that GS-KG9 effectively relieves STZ-induced neuropathic pain by inhibiting microglial activation in the spinal cord dorsal horn and VPL region of the thalamus.

• 한방재활의학과학회지
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• 제18권1호
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• pp.141-151
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• 2008

Objectives : The purpose of this study was to investigate effects of long-term taxi driving posture on the balance of musculoskelectal system. Methods : The author practiced Moire topography by using IBS-2000 for 30 male taxi drivers and general people. Then we measured difference of contour lines, difference of shoulder joint height, interval between vertical baseline of pelvis and vertical baseline of neck, ratio of thoracic curve and lumbar curve, difference of width between right and left through Moire topography. After we statistically analyzed difference of Moire topography's data between long-term employed male taxi drivers and general people. Results : 1. Taxi drivers, difference of contour lines in scapular, lumbar, gluteal region was bigger than general people and significant difference(p<0.05) was observed between subject group. 2. Taxi drivers, diference of shoulder joint height was more large than general people and significant difference(p<0.01) was observed between subject group. 3. Taxi drivers, diference of interval between vertical baseline of pelvis and vertical baseline of neck was more large than general people and significant difference((p<0.05) was observed between subject group. 4. Taxi drivers, ratio of thoracic curve was more large than general people and ratio of lumbar curve was more less than general people and significant difference(p<0.05) was observed between subject group. Conclusions : According to above results long-term taxi driving posture might cause musculoskelectal system unbalance.

• 한국임상수의학회지
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• 제28권1호
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• pp.154-158
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• 2011

A 8-year-old female Shih-tzu dog (weighting 4.5 kg) with history of both hindlimb lameness and cervical mass was presented to Veterinary Teaching Hospital, Gyeongsang National University. In physical examination, ataxia, kyphosis, back pain and cervical mass were identified. Marked periosteal new bone formation of the fourth lumbar vertebra and soft tissue opacity mass of cervical region were observed in survey radiographs. Transverse computed tomography (CT) scan obtained at the lumbar and cervical lesions shown a well defined multilobulated bony mass and partially destructive lytic lesions the fourth lumbar vertebral body and a enlarged retropharyngeal lymph node with heterogeneous contrast enhancement and moderately enhancing left tonsillar mass. Neoplastic squamous epithelium which have developed vessel and lymphocyte infiltration in surrounding tissue were confirmed based on histopathologic examination. Based on the diagnostic findings the dog was diagnosed as a cervical lymph node metastases of tonsillar squamous cell carcinoma.

• 한방재활의학과학회지
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• 제23권4호
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• pp.169-176
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• 2013

Objectives To investigate correlation between anthropometric data (neck circumference (NC), waist circumference (WC), body mass index (BMI), and body shape indexes) and radiological parameters of lumbosacrum. Methods The data of college students living in Seoul (n=24) were analyzed retrospectively. Anthropometric data of NC, WC, and BMI were measured. Lumbar spine X-ray film was taken to measure lumbar lordotic angle, Ferguson's angle. To evaluate body shape of participants, three indexes of neck-to-waist ratio (NWR), neck-to-height ratio (NHR), and waist-to-height ratio (WHR) were used. Anthropometric data's correlations with radiological parameters of lumbosacrum were investigated. Results Anthropometric data of NC, WC, and BMI had no significant correlation with radiological parameters of lumbosacrum. NWR had significant positive correlation with lumbar lordotic angle and Ferguson's angle. NHR and WHR had no significant correlation with radiological parameters of lumbosacrum. Conclusions The results suggest that NWR-related fat distribution in neck has significant correlation with radiological parameters of lumbosacrum regardless of obesity.