• The Korean Journal of Food And Nutrition
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• v.30 no.6
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• pp.1348-1358
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• 2017

To enhance the physiological activity of the Rhynchosia volubilis (RV), R. volubilis (RVHE-A) and R. volubilis-added herbal powder (RVHE-B) were fermented with a solid state culture of Hericium erinaceum mycelia (HE). The total isoflavone contents of the non-fermented RV-A ($489.9{\mu}g/g$) and RV-B ($571.1{\mu}g/g$) were remarkably increased in fermented RVHE-A ($1,836.4{\mu}g/g$) and RVHE-B ($1,276.7{\mu}g/g$). In particular, aglycone isoflavones such as daidzein and genistein were significantly higher in the RVHE-A than any other sample. When hot-water (HW) and EtOH extracts (E) were fractionated from the RV and RVHE, both extracts from the RVHE-A were higher than those from the RV-A in total polyphenol and flavonoid contents. However, the RVHE-B-HW showed a lower polyphenol and flavonoid content level than did RV-B-HW. RVHE-A-HW and -E also had more potent ABTS radical scavenging activity than any extract from the non-fermented RV and other ferments (RVHE-B). In the meanwhile, RVHE-A-HW potently stimulated the production of macrophage activation-related cytokines such as $TNF-{\alpha}$, IL-6 and IL-12 ($841.7{\pm}71.3pg/mL$, $3.9{\pm}0.1ng/mL$, $179.3{\pm}30.2pg/mL$) from peritoneal macrophage more than RV-A-HW ($92.5{\pm}1.5pg/mL$, $0.1{\pm}0.0ng/mL$, $37.4{\pm}5.4pg/mL$) as well as RVHE-B-HW ($557.0{\pm}21.3pg/mL$, $1.8{\pm}0.0ng/mL$, $90.0{\pm}10.0pg/mL$). However, all the EtOH extracts did not show significant activity. In addition, the RVHE-A-HW showed a significantly higher intestinal immune system modulating activity through Peyer's patch and GM-CSF production than did any other extract from RV and RVHE-B. In conclusion, these results suggest that the fermented R. volubilis with H. erinaceum mycelia possesses a possible use as an industrial application as functional food or material.

• Journal of Korean society of Dental Hygiene
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• v.10 no.3
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• pp.523-530
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• 2010

Objectives : In order to provide basic data necessary for developing oral health education plane for school continued oral health education by understanding knowledge and activities of oral health. Methods : This study was performed against 324 students at 5th grade of 2 elementary schools in Iksan-si, Jellabuk-do selected through convenience sampling, who were in mixed dentition period that might experience dental caries of permanent tooth. Results : As results, For the knowledge level on oral health by questions, it was found that the case that the elementary school students had correct knowledge on oral health was 'chocolates, snacks, and candies were foods that might often cause dental caries' and 95.8% of the students recognized it well. It was found that for 'must do toothbrushing before going to bed', 'during toothbrushing, I clean my tongue', and 'Proper time necessary for toothbrushing is about 3 minutes', 89.3%, 93.2%, and 89.3% of the students knew the, respectively. When oral health knowledge level by groups was divided into 3 groups and observed, they were classified into Low (0-4 points), Mid (5-7 points), and High (8-10 points). It was found that the knowledge level of each group was High 64.1%, Mid 33.9%, and Low 2.0% and it was identified that the high group took the largest ratio. It was suggested also for oral health knowledge level depending on their father's academic background that there was a statistically significant difference in the group higher than university graduate(p<.05). It was found for oral health knowledge level depending on parents' dental condition that an answer that both parents were good was high and there was a statistically significant difference. But post-analysis resulted that there was no apparent difference among groups. It was found that the ratio of respondents who answered for toothbrushing method 'toothbrush should be moved and rotated downward for the upper teeth and upward for the lower teeth to clean the teeth and gum' were 33.2% of male students and 29.4% of female students and showed statistically significant difference (p<0.05). It was found also that the ratio of respondents who answered to use a toothbrush for about 3 months' were 29.4% of male students and 25.5% of female students and showed statistically significant difference (p<0.05). Conclusions : Oral health program through the elementary school students and their parents for the development of proper oral health care education programs continue to be made should be considered.

• The Journal of the Korea Contents Association
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• v.18 no.7
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• pp.313-321
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• 2018

This study was conducted to investigate the oral health perception according to the actual condition of oral hygiene products management in 222 college students in Daegu and Kyungbuk province (p<0.05). The subjects in the study were 43 men (19.4%) and 50 women (22.5%) with two toothbrushes (p<0.05), and the major subjects were 2 tooth brushes The subjects were 18 (8.1%) and 75 subjects (33.8%) were subjects of science major (p<0.001). Among the subjects who did not carry a toothbrush, 72(32.4%) were male and 46 (20.7%) were female. The number of subjects who did not carry the male was higher (p<0.05) The subjects were as follows: 83 (37.4%), and 21. Oral health awareness was 3.031 times higher than that of male (p<0.001), and the major group was 2.57 times higher than that of the general population (p<0.001). Subjects who did not sterilize the toothbrush had 0.459 times lower oral health perception (p<0.05). In order to establish and evaluate the oral health policy of university students in Korea, only the objective oral health status is used as an index. However, it is necessary to study and reflect the variables affecting oral health awareness as much as the oral health awareness reflects not only oral health condition but also socioeconomic variables and the effect of variables on oral health.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.4
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• pp.245-253
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• 2018

This study investigated 2,088 economically active workers aged 20 to 65 years selected from the sixth Korea National Health and Nutrition Examination Survey to evaluate the relationship between chronic diseases and oral health behaviors among economic workers and examine the risk factors for oral diseases. The results of the study were as follows. Dental caries were related to subjective oral health status, toothache experience, orthodontic treatment experience, chewing problems, speaking problems, oral examination, and dental clinic use. Periodontal disease was associated with oral health status, toothache experience, orthodontic experience, and chewing and speaking problems. The risk factors for chronic diseases and oral health behavior were as follows. Hypertension, 1.37 times; obesity, 1.48 times; diabetes, 1.5 times; low HDL-cholesterol, 1.31 times; hepatitis A antibody, 1.53 times higher. Health status was found to be 1.70 times higher in dental caries and 2.10 times higher in periodontal disease. The tooth experience was 1.30 times higher in dental caries and 1.35 times higher in periodontal disease. Problems chewing were 1.76 times for dental caries and 1.78 times for periodontal disease. The possibility of dental caries and periodontal disease was 1.44 times higher. Smokers were 1.61 times more likely to have dental caries and 1.63 times more likely to have periodontal disease. These results suggest that periodontal diseases increase the risk of chronic diseases and oral health behavior increases the risk of dental caries and periodontal disease. Although dental caries seem to have a lower risk of becoming a chronic disease if only oral health care is good, it is considered that both chronic disease and oral health care are important for periodontal disease.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.41
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• pp.49.1-49.8
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• 2019

Background: The purpose of this study was to review the clinical features of oromaxillofacial infections in patients presenting to a hospital emergency ward, to identify the key factors affecting the requirement for hospitalization, and the potential risk factors predisposing to a prolonged length of hospital stay. Methods: A retrospective medical record review of the 598 patients treated for oromaxillofacial infection from 2013 to 2017 at the oral and maxillofacial surgery department, Yangsan Pusan National University Hospital, was conducted. The following information was collected from each patient: sex, age, past medical history, site of infection, etiology, admission or outpatient care, level of C-reactive protein (mg/dL), fascial spaces involved, treatment method, and duration of hospitalization. Chi-squared tests were used to identify risk factors, which were further analyzed using multivariable logistic regression. Results: A total of 606 patients were eligible for inclusion in the study, of which eight were excluded due to having incomplete charts; thus, 598 patients were included: 55% were male, mean patient age was 47.1 ± 19.9 years, and 12.9% of patients were diabetic. Furthermore, 71.2% of patients had infection originating in the mandible; the most common tooth of origin was lower posterior, and 29.8% of patients were hospitalized. Risk factors for hospital admission were elderly patients with concurrent disease, elevated C-reactive protein level, and multiple-space infection in the oromaxillofacial area. The duration of hospitalization was correlated with both diabetes and age. Conclusions: The requirement for hospital admission is determined by the severity of the infection; even severe infections, once treated with appropriate surgery, have no relation to the length of hospital stay. The important risk factors for increased duration of hospitalization are diabetes mellitus and older age. The understanding of risk factors associated with a prolonged hospital stay during the treatment of oromaxillofacial infection will aid in treatment planning as well as highlight the importance of adequate diabetes control in patients at risk of such infection.

• The korean journal of orthodontics
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• v.23 no.1 s.40
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• pp.75-88
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• 1993

Recent reports indicate that shorter etching times than 60 seconds can be adopted without affecting the bond strength and clinical disadvantages. The purpose of this in vitro study was to compare the shear bone strength and to measure depth of etch at different etching time length. One hundred and eight extracted bovine lower central incisors were embedded each in a tooth cup with cold-cure acrylic resin. The facial surfaces of the teeth were ground wet with 600-, 800-, 1000-, and 1200-grit Sic papers, and finally polished with a water slurry of extrafine silicon carbide powder, washed with tap water, and dried with hot air. Nine groups of nine prepared teeth were etched with a commercial($38\%$ phosphoric acid solution) for 0, 5, 10, 15, 20, 30, 60, 90, and 120 seconds, respectively, rinsed with tap water, and dried with hot air. One conditioned teeth from every group was selected randomly for the scanning electron microscopic examination, and the remaining eight teeth of the groups were used for measuring the push shear bond strength after bonding brackets and immensing them in the $36.5^{\circ}C$ water for 24 hours. Another nine groups of three teeth were used for measuring the depth of etch and surface roughness with a surface profilometer. after pieces of adhesive tape of 3mm inner diameter positioned on the ground enamel surfaces, and etched with the above mentioned. The data obtained form the above expeiments were analysed statistically with one way ANOVA and Dunkan's multiple range test with the $95\%$ confidence level. The results and conclusion of the study were as follows; 1. The results of shear bond strength for the given experimental etching times were not statistically different, but showed the tendency of decreasing shear bone strength after over 60 seconds etching times. 2. On the scanning election microscopic examination, it was observed that the morphological patterns of etched enamel surface for 5 to 20 seconds were similar and consitent, and those for 30 to 120 seconds showed increasing over-etched patterns depending on the length of etching times. 3. The depth of etch was increased almost proportionally by the length of etching times, but it was not associated with the shear bond strength. 4. The surface roughness increased depending on the length of etching times, but it was not associated with the shear bond strength. 5. This experiment indicated that proper etching time with $38\%$ phosphoric acid solution is in the range of 5 to 30 seconds.

• Journal of the korean academy of Pediatric Dentistry
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• v.43 no.3
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• pp.237-245
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• 2016

This study aimed to identify the characteristics of jaw cysts among children and adolescents treated at the Kyung Hee University Dental Hospital from 2005 to 2015. A retrospective observational study was conducted of 269 jaw cysts diagnosed in 253 patients. The following variables were recorded: gender, age, prevalence and location of lesions, clinical symptoms and treatment. Statistical analyses were performed using the SPSS (version 20.0). Our results suggest that the cysts are slightly more prevalent in males. Cystic lesions of the jaws in children are predominantly odontogenic and developmental in origin. Dentigerous cysts predominate in developmental cysts and the most frequent diagnosis is radicular cysts in inflammation cysts. The most common location of the cysts is in the mandible, particularly the lower molar region. In numerous cases, the patients have no clinical symptoms. Most cysts were surgically enucleated with tooth extraction. Furthermore, our findings demonstrate that the characteristics of jaw cysts in children are distinctive and differ in several respects from the corresponding distribution of jaw cysts in adult population. Therefore, knowledge of the clinical, radiological and histopathological behavior of jaw cysts and periodic radiographic examination are key factors for early diagnosis and adequate treatment of jaw cysts in children.

• Journal of the korean academy of Pediatric Dentistry
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• v.35 no.4
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• pp.731-736
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• 2008

Odontogenic keratocyst is classified as a developmental odontogenic cyst and is believed to arise from cell rests of the dental lamina. It accounts for 3% to 11% of all jaw cysts and they occur twice as often in the mandible as in the maxilla. Histologically, the cysts are lined by stratified, keratinizing, squamous epithelium. Daugther cysts or microcysts are often observed microscopically. The recurrence rate has been reported variously, but is known by its high recurrence rate. These lesions are more common in males than in females, occur over a wide age range and are typically diagnosed during the 2nd and 3rd decade. The diagnosis depends on the cyst’s microscopic features and is independent of its location and radiographic appearances. This cyst is a radiolucent lesion that is often multiloculated, has a smooth or scalloped border. The cyst is characteristically located in the body and ramus of the mandible, and often occurs in conjunction with an impacted tooth. This case report describes an odontogenic keratocyst on the lower right molar area of an 8-year-old girl. The cyst was removed under the general anaesthesia, and is being checked regularly for any recurrences.

• The korean journal of orthodontics
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• v.35 no.6 s.113
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• pp.433-442
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• 2005

The purpose of this study was to evaluate and compare the shear bond strength of orthodontic brackets depending on the variety of adhesives and whether saliva exists, by using self-etching primer (SEP). Groups were divided according to the type of adhesive into resin adhesive (Trans bond XT) and resin-modified glass ionomer cement (Fuji Ortho LC). One group of resin adhesive used XT primer after etching with 37% phosphoric acid, and the other group used self-etching primer. One group of resin-modified glass ionomer cement only used etching for bonding, and the other group used SEP. Each of the groups were also classified by whether saliva was contaminated or not. and then the shear bond strength was measured. The results showed that when using resin adhesive, the shear bond strength of SEP was lower than the XT primer. In the resin-modified glass ionomer cement groups, the shear bond strength which depends on the priming method, did not have a meaningful difference statistically When saliva was contaminated, the group which used SEP, regardless of the adhesive variety, had a greater shear bond strength than the normal priming group. From these results, SEP showed a shear bond strength that is possible to be used clinically, regardless of the adhesive variety. It can especially be clinically useful to use SEP to bond brackets even on tooth surfaces contaminated with saliva, because it offers the appropriate bonding strength as well as shorter treatment time and easy application.

• The Journal of Korean Academy of Prosthodontics
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• v.28 no.2
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• pp.1-28
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• 1990

The severe atrophic edentulism with poor neuromuscular control militates against successful conventional denture therapy. To such situation, a prescribing of dental implant treatment has been considered with some probability. Implant materials used as a trial for dental implants includes metals, plastic polymers and ceramics. The purpose of this study was to observe histologic response in osseointegration process at titanium implant-tissue interface based on biocompatibility at specific period of sequential natures which were divided into a half month, one, month, two months, three months and immediate as a base line. In this study, unilateral lower left premolar and molar teeth were extraced in three dogs. After allowing to heal for 6 months, three kinds of osseointegrated implant, $Br{\aa}nemark$, Corevent and kimplant(a prototype of SNU implant study)were inserted in each dog respectively according to the above sequence from front to back. The specimens were taken from those dogs at the same time since implant were inserted quite reverse order of the specified periods, and decalcified and processed for histologic examination for the light microscopy and the electron microscopy. The microscopic histologic findings at the interface between titanium implants and tissue were interpretated as follows : A. Light microscopic findings : a. Immediate : Implant were surrounded by compact bone and spongy bone. Microcrak was observed in the superficial bone tissue. Osteocytes were disappeared and bone lacunae were observed as a vacant space in some parts. In the contacting with the spongy bone, bone trabeculae and bone marrow were in contact with the implant. b. A half Month : Osteoblasts exist as a monolayer in th inner bone trabeculae and do bone additiocn. Osteoblasts&inflammatory cells were observed in some parts. c. One Month : The presence of osteoclasts decreased. Osteoblasts did active bone fromation, and bone marrow was in contact with the implant in the many places. d. Two Months : Bone formation was advanced in comparison with the b and c. The presence of osteoclsts was not observed. e. Three Months : The superficial bone tissue contacted with the implants was entirely composed by the compact bone. B. Electron microscopic findings : a. A half month and one month group : In the parts of the active bone formation, osteoblasts with the well developed endoplasmic reticulum and Golgi apparatus were arranged in the monolayer. In the parts of the bone resorption, ruffled border was well developed and many osteoclasts with the well-developed golgi apparatus, mitochondria, vacuole, vesicle and lysosome were existed. b. Three months group : No osteoblasts were observed in the superficial bone tissue. Bone matrix with collaen fiber was observed. c. No significant dirrerence in the histologic findings was observed in $Br{\aa}nemark$, Core-vent and kimplant.